Lock and key - Factbites

Lock and key - Factbites
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Topic: Lock and key

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	Enzyme - Wikipedia, the free encyclopedia
		In 1958 Daniel Koshland suggested a modification to the "lock and key" model.
		Enzymes are very specific and it was suggested by Emil Fischer in 1890 that this was because the enzyme had a particular shape into which the substrate(s) fit exactly.
		Enzymes are usually specific as to the reactions they catalyze and the substrates that are involved in these reactions.
	en.wikipedia.org /wiki/Enzyme (2947 words)

	Under Lock and Key - Wikipedia, the free encyclopedia
		Under Lock and Key is the 3rd album by heavy metal band Dokken, released on November 9, 1985.
		The album has sold over three million copies in the US and more than six million copies worldwide.
		This page was last modified 11:50, 17 February 2006.
	en.wikipedia.org /wiki/Under_Lock_and_Key (141 words)

	Howstuffworks "How Lock Picking Works"
		On your key ring you might have several keys for the house, one or two more for the car and a few for the office or a friend's house.
		Your key ring is a clear demonstration of just how ubiquitous lock technology is: You probably interact with locks dozens of times every week.
		Keys are one of the most basic and essential machines we use every day.
	www.howstuffworks.com /lock-picking.htm (202 words)

	CELLULAR RESPIRATION How Cells Obtain Energy To Sustain Life
		LOCK and KEY MODEL OF ENZYME AND SUBSTRATE
		(b) The lock-and-key model of enzyme function: The lock-and-key model is a hypothesis to explain how proteins act as efficient and specific catalysts.
	www.umbc.edu /bioclass/biol100a/Lecture6/Lecture6_files/slide0018.htm (40 words)

	Enzymes
		Enzymes are organic catalysts that speed up a chemical reaction by lowering the energy of
		Enzymes must have the best environmental conditions to operate most efficiently.
		Enzymes can be synthetic (build up) or hydrolytic (breakdown..digest)
	www.troy.k12.ny.us /thsbiology/skinny/skinny_enzymes.html (135 words)

	Carboxypeptidase
		Three hydrogen bonding and electrostatic interactions are critical for the enzyme to recognize the terminal amino acid in the peptide chain.
		The residues Arg 145 and Tyr 248 from the enzyme form hydrogen bonds with the protein.
		This is a molecular model of the unbound carboxypeptidase A enzyme.
	www.chemistry.wustl.edu /~edudev/LabTutorials/Carboxypeptidase/carboxypeptidase.html (1052 words)

	Under lock and key
		The Lock and Key stay in constant radio communication (up to 50 feet, or 15 meters) to determine user identity and location relative to the computer.
		It consists of a radio transceiver (called a "Lock") that plugs into the computer and a discrete wireless radio transmitter (called a "Key") worn by the user.
		I suggested using the same card for unlocking the proximity locks on secured doors so that users would have to remove the cards from the readers and keep it with them when they left their desks so that they could open any doors along the way.
	www.networkworld.com /newsletters/dir/2002/01297751.html (665 words)

	NewsForge Keeping email under lock and (public) key
		The simplest arrangement might be giving the key (we'll see in a short while how to export it) to one or more officers of your company, and the passphrase to another.
		Key size: The longer your key, the more secure your archive it will be, but the slower things will run.
		For added security, the secret key can be split in two or more pieces, in such a way that only with all the pieces the archive can be opened.
	software.newsforge.com /software/05/06/27/1614233.shtml?tid=152&tid=78 (1722 words)

	UNDER LOCK AND KEY
		Non-English Usage: "UNDER LOCK AND KEY" is also a word in the following language with the English translation in parentheses.
		Adjective: restrained, constrained; imprisoned;Verb: pent up; jammed in, wedged in; under lock and key, under restraint, under hatches; in swaddling clothes; on parole; in custody, doing time; (prisoner); cohibitive; coactive; (compulsory).
		Adjective: imprisoned; in prison, in quod, in durance vile, in limbo, in custody, doing time, in charge, in chains; under lock and key, under hatches; on parole.
	www.websters-online-dictionary.org /definition/UNDER+LOCK+AND+KEY (313 words)

	Official George Lynch Website - Under Lock and Key Recording
		For the album, "Under Lock And Key," there are tonal textures that are the results of the use of the Roland GR-707.
		Above is the TS-808 that has been present for most of Lynch's recording career, as was used during the 1985 recording of Dokken's "Under Lock And Key" album.
		Official George Lynch Website - Under Lock and Key Recording
	www.georgelynch.com /rigs/studiorigs/underlockstudio.html (583 words)

	MuscatineJournal.com
		Made by Humboldt-based C&K Manufacturing Inc., the valve lock consists of a red and white hardened steel cap combined with a metal backplate, valve sleeve, a weatherproof stainless steel tubular padlock and a special key.
		Monday morning, drug task force officials and Dave Christianson, inventor and manufacturer of the "Tanks-A-Lok" anhydrous ammonia tank valve lock, distributed 94 of the devices, free of charge, to representatives of the Nichols Agriservice LLC, Sweetland Ag Tech and UAP Midwest fertilizer dealerships in Muscatine County.
		The cost of the tank locks were paid for through a $300,000 federal drug task force grant sponsored by U.S. Sen. Tom Harkin and channeled through the Iowa Governor's Office of Drug Control Policy, Christianson said.
	www.muscatinejournal.com /articles/2005/08/16/news/doc430202bf9dd65108068986.txt (716 words)

	Under Lock and Key
		To obtain the highest rating with regard to key control, key blanks must not be available from a second source and must be protected by law.
		A new standard provides guidance to those who specify the cylinder locks on doors and should increase the confidence of the owners and occupants who depend on such locks.
		Recently, master key duplication has received increased attention, in part due to a broadly publicized paper by digital security expert Matt Blaze, who described how the number of theoretical key changes to decode the master key is reduced for a person who possesses a key that belongs to the master key system.
	www.usglassmag.com /backissues/0306/Lock.html (1264 words)

	Under lock and key - Elizabeth Farrelly - www.smh.com.au
		Under lock and key - Elizabeth Farrelly - www.smh.com.au
		As for uncertainty, Australand's disgruntlement seems to be more about the opposite, namely Clover's insistence on not bending the rules to suit.
		Back under the old regime, when city development rules behaved like bits of old knicker-elastic, Crotty sounded positively relaxed.
	www.smh.com.au /news/Elizabeth-Farrelly/Under-lock-and-key/2005/03/28/1111862318077.html (1369 words)

	IT Architect Keeping PKI Under Lock and Key October 5, 2000
		When the secret key is entered into the system to verify a signature or to encrypt data, steps must be taken to ensure that the key is not exposed longer than absolutely necessary to complete the task.
		If this key is compromised by an intruder, the intruder could then issue certificates for fictitious identities, which would be trusted by all PKI users (because the certificates would carry a legitimate signature).
		Ideally, the secret key should be stored offline in a secondary storage device, such as a diskette, or in a hardware token that can be inserted in the network device when needed.
	www.networkmagazine.com /article/NMG20001004S0015 (1650 words)

	Record Store Geek: Under Lock & Key
		This simple technique uses a modified key to open most any key-based lock.
		Locks are everywhere, but are they doing their job?
		* A pdf guide to lock bumping along with an hour long video on the subject.
	www.recordstoregeek.com /2005/09/under-lock-key.php (127 words)

	MIM Notes Under Lock & Key no. 173 (November 1, 998): Brutality and framings within prison, more censorship, 5% struggle in South Carolina
		I remember reading MIM Notes (beginning of this year /end of last year), Under Lock and Key and the Comrade stated that we are laboratory mice in a big ass laboratory, just being used for experiments.
		I'm telling you, don't think for a second that these KKKlowns do not keep an eye on the "Under Lock and Key" portion of MIM Notes.
		Under prison rules, since we are not charged or convicted of breaking any prison rules, we are entitled to recreation and showers once a day, all of our private property, access to the phones, and access to the legal and educational library.
	www.etext.org /Politics/MIM/ulk/ulk/ulk173.html (2659 words)

	Under Lock and Key RAIL Radio Program
		This is Under Lock and Key The death penalty is defeated again in Massachusetts Black cops speak up for revolutionary prisoner Mumia Abu Jamal And Mumia describes torture on death row Welcome to Under Lock and Key, news and commentary about prisons from the Revolutionary Anti-Imperialist League.
		All of the speakers stressed voting as a key to activism against the death penalty.
		A brutal killing of a young boy last year was turned into a key argument behind the need for the death penalty.
	www.etext.org /Politics/MIM/ma/radio/radio04-23-99.html (1596 words)

	Enzyme Practice Quiz/AP Biology
		The “lock and key” model of enzyme action illustrates that a particular enzyme molecule (1) forms a permanent enzyme-substrate complex (2) may be destroyed and resynthesized several times (3) interacts with a specific type of substrate molecule (4) reacts at identical rates under all conditions
		An enzyme is generally named by adding ____ to the end of the name of the _____.
		Compounds similar in shape to an enzyme's substrate, that can compete with the substrate molecules by binding with the active site of the enzyme are said to be _______________.
	www.ekcsk12.org /science/apbio/enzymeqz.html (1338 words)

	Mailing List complex-science@necsi.org Message 3278
		1) The lock-and-key model of Emil Fischer proposed in 1890,
		2) The induced-fit model proposed by Daniel E. Koshland, Jr.
		enzymes and their substrates seems consistent with both of the following
	necsi.org:8100 /Lists/complex-science/Message/3278.html (661 words)

	active site of an enzyme
		After binding of the enzyme to the substrate is initiated, a conformational change in the shape of the active site which results in a new shape of the active site that is complementary to the shape of the substrate.
		In the induced fit model of enzyme-substrate binding, the shape of the active site of the unbound enzyme is not the exact complement of the shape of the substrate.
		This is so illustrated to indicate that the enzyme can recognize the substrate based, at least in part, on its shape.
	academic.brooklyn.cuny.edu /biology/bio4fv/page/active_.htm (176 words)

	Enzymes as Catalysts
		Organ specific enzymes with slight amino acid differences- They have the same activity and are easily separated using biochemical techniques.
		Enzyme is a biological catalyst which increases the rate of chemical reactions.
		Enzyme is working on the substrate (job) until you have 100 % employment.
	www.hartnell.cc.ca.us /faculty/asteinhardt/mywebs/EnzymeMetabolism.htm (1295 words)

	15
		That is because the enzyme has multiple subunits and the enzyme's activity varies in a way we will discuss.
		Enzymes generally have Km values that are close to the physiological concentrations of their substrates.
		The model requires that the enzyme have at least two subunits that are all in the same conformation.
	nsm1.utdallas.edu /bio/DGray/Syllabi/Fall_03/3361GG15.htm (1581 words)

	Cells: Structure and function, Chapter 2
		This 'key' is the substrate for that enzyme.
		It can be shown that proteins, and therefore enzymes, are held in their correct 3-D structure by a combination of a few strong chemical bonds and very many weak chemical bonds.
		The enzymes for aerobic respiration are located in the mitochondria, so the first step in the process is the entry of the pyruvate from glycolysis into these mitochondria.
	www.biologie.uni-hamburg.de /b-online/library/cat-removed/u3aos12.html (2174 words)

	Molecule Illustrations
		The enzyme is unaltered during the reaction and is free to catalyze the breakdown of another substrate molecule.
		In the simplified "sandwich model" of a cell membrane, a phospholipid bilayer is sandwiched between two layers of protein.
		In the "fluid mosaic model" of membrane structure, the membrane is a fluid phospholipid bilayer in which protein (glycoprotein) molecules are either partially or wholly embedded.
	waynesword.palomar.edu /molecu1.htm (2598 words)

	Enzymes - Lock&Key
		Smaller keys, larger keys, or incorrectly positioned teeth on keys (incorrectly shaped or sized substrate molecules) do not fit into the lock (enzyme).
		In the graphic on the left, the substrate is represented by the magenta molecule, the enzyme protein is represented by the green and cyan colors.
		The induced-fit theory assumes that the substrate plays a role in determining the final shape of the enzyme and that the enzyme is partially flexible.
	www.elmhurst.edu /~chm/vchembook/571lockkey.html (635 words)

	Enzyme Quiz
		Enzymes influence chemical reactions in living systems by (1.) providing the substrate required for the reaction to occur (2.) affecting the rate at which reactions occur (3.) absorbing water released when polymers are formed (4.) combining with excess hydrogen to form gaseous wastes
		peroxide (4.) enzyme in the breakdown of hydrogen peroxide
		In enzyme controlled reactions, the role of certain vitamins such as niacin is to act as (1.) an enzyme (2.) a substrate (3.) a coenzyme (4.) a polypeptide
	www.ekcsk12.org /science/regbio/enzymequiz.html (1517 words)

	Lock And Key Analogy - Super Locks Guide
		The lock - and - key analogy in biology draws a correspondence between the fitting of a key in a lock and the stereospecific fit between bio-molecules...
		To use the lock and key analogy, the greater the number of keys, the more difficult it is to find the correct key to fit into the lock that protects the...
		In this context it is useful to extend the lock - and - key analogy of biological interactions [Rastetter, 1983,Gilbert and Greenberg, 1984].
	www.superlocksguide.com /lock-and-key-analogy.html (671 words)

	lock-and-key model - definition from Biology-Online.org
		A model used to suggest the mode of operation of an enzyme in which the substrate fits into the active site of the protein like a key into a lock.
	www.biology-online.org /dictionary/lock-and-key_model (48 words)

	EnzymeLecture.doc
		Lock and Key Model In this model the enzyme recognizes a shape or region of a substrate.
		The key to an enzyme’s activity is its shape!
		The more enzyme and substrate, the faster the rate of reaction.
	ghs.gresham.k12.or.us /science/winters/Text/Anatomy/EnzymeLecture.doc (308 words)

	An Inquiry Laboratory Activity for Biology
		Students read about catalysts and enzymes in the textbook, we discuss in class the "lock-and-key" model for enzyme/substrate, and the chemical makeup and structure of enzymes.
		This activity has been traditionally used as the focal point of our unit on enzymes since it demonstrates the difference between an inorganic catalyst and an enzyme, shows that enzymes are not "used up" in a reaction, and vividly shows the conditions under which enzymes work best or don't work at all.
		After some thinking, they realized that since enzymes are contained in cells, grinding must open up the cells and the enzymes are then free to react with the substrate.
	www.accessexcellence.org /AE/AEC/AEF/1994/contolini_inquiry.html (1129 words)

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