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Topic: Locus (genetics)

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	Finch Genetics -FinchInfo.com-
		The locus is the position that a given gene occupies on a chromosome.
		The genotype or genetic makeup for this bird, therefore is single-factor for white breast, single-factor for purple breast.
		The expression of a genotype in the appearance of an organism; the observed trait.
	www.finchinfo.com /genetics (1656 words)

	Locus - Wikipedia, the free encyclopedia
		Locus (genetics), the position of a gene (or other significant sequence) on a chromosome.
		Locus (mathematics), the set of points satisfying a particular condition, often forming a curve of some sort.
		In the classics, literature or theology, locus (or locus classicus) marks the first appearance of a phrase or the definitive passage that is authoritative for an idea.
	en.wikipedia.org /wiki/Locus (232 words)

	Basic Population Genetics [M.Tevfik Dorak]
		Genetic distance is a measurement of genetic relatedness of samples of populations (whereas genetic diversity represents diversity within a population).
		The estimate is based on the number of allelic substitutions per locus that have occurred during the separate evolution of two populations.
		For the genetic loci subject to natural selection, the evolutionary rate is not the same for each population and therefore UPGMA should be avoided for the analysis of such loci (including the HLA genes).
	dorakmt.tripod.com /genetics/popgen.html (5059 words)

	Tetrahymena Genetics (Site not responding. Last check: 2007-10-16)
		As in other eukaryotes, genetic linkage maps of loci in individual chromosomes are constructed by exploiting the fact that meiotic crossing over generates recombinant genotypes with a frequency which, in the linear portion of the range, is roughly proportional to physical distance [see any genetics textbook, e.g.
		For certain natural genetic polymorphisms in surface antigen (serotype), extremely biased initial amplification of one particular allele (in the absence of differential vegetative replication) is sufficient to explain the observed appearance of lack of assortment [27]
		By analogy to well established genetic observations in Paramecium [30], it has been proposed that in these variants the altered cytoplasm in which a new MAC differentiates can hereditarily determine the state of expression of the serH locus in the asexual clone that carries descendants of that MAC.
	www.ciliate.org /genetics.shtml (7530 words)

	Locus (genetics) - Wikipedia, the free encyclopedia
		In biology and evolutionary computation, a locus is a fixed position on a chromosome, such as the position of a gene.
		Gene mapping is the process of determining the locus for a particular biological trait.
		For example, the locus of gene OCA1 may be written "11q14-q21", meaning it is on the long arm of chromosome 11, somewhere in the range of sub-band 4 of band 1, and sub-band 1 of band 2.
	en.wikipedia.org /wiki/Locus_(genetics) (280 words)

	Angelfish Genetics
		Since mutations are random in the genetic code and the proper code is very specific, useful mutations of a major proportion are rather unlikely.
		Recessive: When different alleles occur at the same locus and one of the alleles is not expressed in the presence of the other, the non-expressed trait is considered recessive.
		Dominant: When different alleles occur at the same locus and one of the alleles is not expressed in the presence of the other, the expressed trait is considered dominant.
	www.angelsplus.com /genetics.htm (2188 words)

	Nigerian Dwarf Color Genetics
		Genetically, an animal that is buckskin with so much white spotting that it's difficult to determine the animal's pattern is every bit as much a buckskin as the animal with no white spotting at all.
		Browns produced by the B locus differ from the tans produced at the Agouti locus in that the brown coloration is found only in areas of the coat that would otherwise be fl, and that the brown is chocolate-brown, not yellow or red-brown.
		Almost all red goats are red due to alleles at the Agouti locus or to unknown modifier genes, not due to the Brown locus.
	members.cox.net /foxcroft/genetics.htm (4135 words)

	Population Genetics (Stanford Encyclopedia of Philosophy)
		Population genetics is a field of biology that studies the genetic composition of biological populations, and the changes in genetic composition that result from the operation of various factors, including natural selection.
		In the one-locus case, we saw that in a large randomly mating population, there is a simple relationship between the frequencies of the gamete types and of the zygotic genotypes that they form.
		By contrast, quantitative genetics does not directly deal with gene frequencies; the aim is to track the phenotype distribution, or moments of the distribution such as the mean or the variance, across generations.
	plato.stanford.edu /entries/population-genetics (9394 words)

	Kidd Lab - Publications
		Genetic and physical mapping and population studies of a fibronectin receptor Beta-Subunit-like sequence on human chromosome 19.
		Genetic and physical mapping of the Treacher Collins syndrome locus with respect to loci in the chromosome 5q3 region.
		Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus (PAH) in a global representation of populations.
	info.med.yale.edu /genetics/kkidd/pubs.html (6545 words)

	Heritage Alpaca Sale (Site not responding. Last check: 2007-10-16)
		Comprehension of basic genetic principles is crucial, however, to the understanding of more complicated issues such as inheritance of genes coding for fleece color and patterns.
		Fellow alpaca breeder Dr. Patricia Craven explained to readers in Basic Molecular Mechanisms in Genetics (2000): "A gene is a sequence of DNA which encodes a single protein." Once a gene is identified as contributing to a particular trait, scientists label its locus for the simple purpose of communication.
		Since true pinto spotting is often the result of a recessive genetic mechanism in mammals, we may assume that both alleles (forms of the gene) at the Spotting locus must code for the pinto pattern in alpacas.
	www.alpacaheritage.com /genetics2.html (1833 words)

	AFRMA - Rat Genetics, part 1
		Genetics is not some mystical system for predicting the color of animals, nor is it an elaborate mathematical equation which can only be solved by a brilliant scientist.
		Each locus is responsible for a distinctive effect on the pigment in the coat, and all the loci taken together “spell out” what the rat will look like.
		This locus causes pigment to be globbed together in big clumps instead of being distributed in the normal, even manner.
	www.afrma.org /ratgenpart1.htm (1898 words)

	The Learning Center - Genetics 401
		Locus - Gene pairs in all life forms are always connected in a particular order.
		It is very important to understand that while each locus accepts only two alleles, there may be several types of alleles which may fit at that locus.
		Remember that in most cases, both alleles at that locus must be mutated for the appearance of the animal to be altered.
	www.vmsherp.com /LCGenetics401.htm (1014 words)

	The Individualist: Locus
		A locus is the place on a chromosome where a specific gene is located, a kind of address for the gene.
		The chromosomal locus of a gene might be given as "9q34.1".
		For example, the locus of gene OCA1 might be given as 11q14-q21, meaning it is on the long arm of chromosome 11, somewhere in the range of sub-band 4 of band 1, and sub-band 1 of band 2.
	www.dadamo.com /wiki/wiki.pl/Locus (427 words)

	Genetics
		The strongest genetic association found in this study was between allelic variation in alpha-tubulin, a gene involved in the formation of cortical microtubules, and earlywood microfibril angle.
		The present first multi-gene association genetic study in forest trees has shown the feasibility of candidate gene strategies to dissect complex adaptive traits, provided that genes belonging to key pathways and appropriate statistical tools are used.
		We performed an unbiased genetic screen for mutations that permit the survival of cells being competed due to haploinsufficiency for RpL36.
	barf.jcowboy.org /genetics.xml (5430 words)

	Human Genetics - Population Genetics
		Genetic polymorphisms often are detrimental to the homozygote, but they allow others of the species to survive.
		Population genetics is concerned with gene and genotype frequencies, the factors that tend to keep them constant, and the factors that tend to change them in populations.
		For the MN blood group locus there can be little doubt that the conditions for Hardy-Weinberg equilibrium are met in the human population, at least the population in London where the sample was taken.
	www.uic.edu /classes/bms/bms655/lesson13.html (3937 words)

	Model Horse Reference -- Genetic Glossary
		An allele is a segment of "genetic instructions" that affect a trait or characteristic.
		The locus that is masked, or overridden, is referred to as the Hypostatic locus.
		That is, the genetic material "crosses over" in groups and blocks of amino acids (rather than completely randomly) and the linked alleles are very likely to be transferred to the offspring together as a "team".
	www.mhref.com /color/genetics/glossary.html (969 words)

	Department of Genetics (Site not responding. Last check: 2007-10-16)
		Molecular basis of the pleiotropic phenotype of mice carrying the hypervariable yellow (Ahvy) mutation at the agouti locus.
		Insertion of an Alu SINE in the human homologue of the Mlvi-2 locus.
		A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion.
	www.med.upenn.edu /genetics/labs/kazazian/references.html (1577 words)

	Basic Genetics
		My genetics pages are based on books, journal articles, personal observations and other web pages.
		Here are some of these references, first general mammalian genetics, then dogs, including a breakdown by breed, and finally references and web pages on other mammals.
		These are the refereces used in writing the pages on basic genetics, multiple-locus genetics, and canine color genes, as well as more pages to come.
	bowlingsite.mcf.com /Genetics/Genrefs.html (611 words)

	Site Template -- Geneology
		The Agouti locus controls the formation of the Agouti protein, that in turn is one of the mechanisms that controls the replacement of eumelanin with phaeomelanin in the growing hair.
		Dominant fl (K) is epistatic to whatever is found at the Agouti locus (simply means that it causes the Agouti allele to act differently from what it normally would), however; "e/e" is dominant to "K" at the E locus.
		If the dog is E/E or E/e at the E locus, and at the K locus, it is "k/k" the distribution of eumelanin and phaeomelanin will be determined solely by the Agouti alleles present.
	www.acdgenetics.caviesrule.com (4635 words)

	Basic Genetics
		I will assume it is at a separate locus K, with K being dominant fl, epistatic to anything at the A series, while kk allows the A series to show through.
		Functionally we can consider that the A locus determines where eumelanin and phaeomelanin are produced, the K locus allows only eumelanin to be produced if E is at the E locus, but ee at the E locus overrides that to allow only phaeomelanin production.
		K at the K locus is epistatic to the A locus, but ee (pure recessive at the E locus) is epistatic to both the A and the K locus.
	bowlingsite.mcf.com /Genetics/BasGen2.html (1560 words)

	Color Genetics
		A locus (loci for plural) is an address or a location where two genes live on a chromosome pair.
		The other locus is called the Agouti locus and its' two genes are responsible for determining whether the horse will be a bay or fl.
		In coat color genetics, when dominant genes are present they are usually visible to us (except in the case of solid red horses) and are given precedence over recessive genes.
	www.lattefarms.com /colorgenetics.html (2398 words)

	Cat Fanciers: Color Genetics
		If you are interested in the genetics of different colors and in what colors are theoretically possible, read section B. Section B is more technical.
		Dilution is a mutation at the (D) locus; dilution is recessive to dense coloration.
		All of these theories seek to explain the genetic factors that apparently suppress the synthesis of pigment after a certain point in the growth of the hair shaft.
	www.fanciers.com /other-faqs/color-genetics.html (3447 words)

	Locus - EvoWiki (Site not responding. Last check: 2007-10-16)
		In genetics, a locus is a gene's location on a chromosome.
		A locus can be occupied by one of a number of alleles for the gene.
		This page is part of the EvoWiki encyclopedia of genetics and molecular biology.
	wiki.cotch.net /wiki.phtml?title=Locus (112 words)

	Epigenetic inheritance at the agouti locus in the mouse - Nature Genetics
		Epigenetic inheritance at the agouti locus in the mouse
		Thus epigenetic inheritance may not be an uncommon occurrence in mammals, although it may be difficult to distinguish from genetic inheritance: variable expressivity and incomplete penetrance are frequent features of genetic syndromes, but their basis is poorly understood.
		Brink, R.A. A genetic change associated with the R locus in maize which is directed and potentially reversible.
	www.nature.com /ng/journal/v23/n3/full/ng1199_314.html (3147 words)

	Genetics
		Micronuclear (germline) genetics Mendelian genetics Inducible conjugation variants Mapping genetically the MIC genome 3.
		Genetics of the macronucleus DNA rearrangements during macronuclear differentiation Phenotypic assortment Coassortment Mapping genetically and molecularly the MAC genome 4.
		Special topics of MAC genetics Sexual maturity Mating type differentiation Genetics of the ribosomal RNA gene (rDNA) MAC DNA replication and copy number control 5.
	www.lifesci.ucsb.edu /~genome/Tetrahymena/genetics.htm (7567 words)

	Sigi's Sauhaufen/Genetics Page
		Note that the abbreviations and letters used for the genetic factors are sometimes different in foreign literature, however, that doesn't change the basics of the inheritence at all, the literature is just not unique in the way it names the factors.
		If two genes on one locus are the same, then the animal is homocygote (breeds true) for this trait.
		The genotype is the genetical buildup (the genetic appearance) of an animal with all genes, recessive and dominant (see above).
	www.sigissauhaufen.de /geneticsengl.html (1725 words)

	4 Basic Genetics
		However, the height of the dog, the ears, the hip rating, the missing premolar, and the double rear decals are probably not single-gene traits, but rely on the interaction of several pairs of genes, with perhaps some influence from the environment.
		An example in dogs is recessive yellow, ee, in which recessive yellow, although a recessive at its own locus, can hide whatever the dog carries at the A locus and the proposed K (dominant fl) locus.
		Many genetic diseases, especially those that can be traced to an inactive or wrongly active form of a particular protein, are inherited in a simple recessive fashion.
	www.riospitbull.com /4_basic_genetics.htm (2378 words)

	Myriad Genetics Publishes Major Obesity Gene Locus
		The statistical support for this linkage is extensive and unparalleled in obesity genetics research, demonstrating the Company's ability to successfully apply its suite of innovative linkage analysis tools to a complex genetic disease.
		The authors conclude that, given the magnitude of the LOD score, at 11.3, and because almost half of the families with severe obesity in this study are linked to this region, this gene could explain a significant percentage of severe obesity.
		Steven C. Hunt, Ph.D., Professor of Medicine and Head of Cardiovascular Genetics at the University of Utah School of Medicine, added, "These interesting results could not have been obtained without the cooperation of many Utah families, for which we are sincerely grateful.
	www.myriad.com /news/release/279363 (755 words)

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