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Topic: Long QT syndrome

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	Long QT Syndrome and Brugada Syndrome
		Catecholaminergic Polymorphic VT The proteins involved in the Long QT Syndrome consist of two of the potassium "channels" which regulate the behaviour of potassium ions moving from the inside to the outside of the cell.
		Long QT 1-3 comprises 95% of all cases of congenital Long QT Syndrome.
		Long QT 1 and 2 are due to mutations in potassium channels, whereas Long QT 3 is as a result of mutation in sodium channels.
	www.c-r-y.org.uk /long_qt_syndrome.htm (1388 words)

	Long QT syndrome - Wikipedia, the free encyclopedia
		The long QT syndrome (LQTS) is a heart disease in which there is an abnormally long delay between the electrical excitation (or depolarization) and relaxation (repolarization) of the ventricles of the heart.
		The QT interval is measured from the Q point to the end of the T wave.
		The syndrome is characterized by Long QT syndrome with ventricular arrhythmias, periodic paralysis and skeletal developmental abnormalities as clinodactyly, low-set ears and micrognathia.
	en.wikipedia.org /wiki/Long_QT_syndrome (1989 words)

	dreddyclinic.com - Long QT syndrome (LQTS)
		Long QT syndrome (LQTS) is a congenital disorder characterized
		Long QT syndrome is rare and often goes undiagnosed or misdiagnosed as a seizure disorder, such as epilepsy.
		While genetic testing for long QT syndrome has been available on a limited basis for a number of years, a more commercially available genetic screening test for long QT syndrome was expected to be introduced in the summer of 2004.
	www.dreddyclinic.com /findinformation/ll/longqtsyndrome.htm (2151 words)

	Long QT syndrome: Facts and details from Encyclopedia Topic (Site not responding. Last check: 2007-11-03)
		Andersen-tawil syndrome, also called andersen syndrome and long qt syndrome 7 is a form of long qt syndrome....
		Jervell and lange-nielsen syndrome is a condition that causes profound hearing loss and arrhythmia, it is a type of long qt syndrome....
		Wolff-parkinson-white syndrome (wpw) is a syndrome of pre-excitation of the ventricles due to an accessory pathway known as the bundle of kent....
	www.absoluteastronomy.com /encyclopedia/l/lo/long_qt_syndrome1.htm (3096 words)

	Selected Encyclopedia of Heart Diseases and Conditions (Site not responding. Last check: 2007-11-03)
		An abnormally long interval between the Q and the T wave (see the section on ECG) called "long QT syndrome," is another common type of arrhythmia and can occur from a variety of both inherited and non-inherited problems.
		This is a form of long QT syndrome (see cardiac arrhythmia and ECG) that is inherited as an autosomal dominant trait.
		The long QT interval results from abnormal electrical conduction in the heart and can lead to brief loss of consciousness (syncope) and sudden death.
	www.hhmi.org /biointeractive/vlabs/cardiology/content/cg/encyclopedia.html (1751 words)

	Genaissance - Long QT Syndrome (Site not responding. Last check: 2007-11-03)
		At least one group of researchers believes that long QT syndrome is a cause of sudden infant death syndrome (SIDS) [2].
		Possibly, there are other genes involved in long QT syndrome or the current methods of detecting genetic variants may not be comprehensive enough [3].
		Prolongation of the QT interval and the sudden infant death syndrome.
	www.genaissance.com /pharmacogenomics/longQT_Syndrome.asp (2028 words)

	Sudden Arrhythmia Death Syndromes (SADS) Foundation.
		The QT interval is a quantity measured on the electrocardiogram (ECG or EKG).
		In the long QT syndrome, the duration of repolarization is longer than normal, thus, the QT interval is prolonged.
		This is manifest on the electrocardiogram (ECG, EKG) by a prolonged QT interval.
	www.sads.org /LQTS.html (2928 words)

	ABC News: For the Faint of Heart: Living with Long QT Syndrome (Site not responding. Last check: 2007-11-03)
		Long QT syndrome is a fairly rare heart condition, affecting about 1 in 6,000 people.
		While two-thirds of all patients with long QT syndrome have a genetically inherited form of the disease, there are about 50 medications, such as some antidepressants, antibiotics, antihistamines and cholesterol-lowering drugs, that are known to cause the condition in otherwise "healthy" people.
		Long QT syndrome is a problem in the heart's electrical wiring.
	abcnews.go.com /Health/Healthology/story?id=729251 (523 words)

	s000626c - Long QT Syndrome - Congenital & Acquired
		Long QT syndrome is an inherited disease that few years ago was still called "idiopathic" as the underlying causes were unknown.
		Abstract: The idiopathic long QT syndrome is a congenital disease characterized by prolongation of the QT interval and by stress-induced syncopal episodes caused by the development of "torsades de pointes".
		In the case of the acquired long QT syndromes, the therapeutic challenge is to maintain the prolonged repolarization but to interrupt the arrhythmogenic cascade.
	www.emory.edu /WHSCL/grady/amreport/litsrch99/s000626c.html (6297 words)

	Find long QT syndrome treatment options and information at Mayo Clinic
		The Long QT Syndrome Clinic and Sudden Death Genomics Laboratory at Mayo Clinic in Rochester have one of the most comprehensive programs internationally for families affected with this condition.
		Treatment for long QT syndrome depends on what type of LQTS the patient has.
		Long QT syndrome (LQTS) is a rare, and sometimes fatal, heart rhythm disorder that is often present from birth.
	www.mayoclinic.org /long-qt-syndrome (323 words)

	BBC - Health - Conditions - Long QT syndrome
		Long QT syndrome is a disorder of the electrical system of the heart and one of a range of conditions that cause unexplained sudden death in a young person.
		The QT interval is the time it takes for depolarisation and repolarisation of the ventricles of the heart.
		In long QT syndrome, the duration of repolarisation (or recharging of the electrical system after each heart beat) is longer than normal.
	www.bbc.co.uk /health/conditions/longqt1.shtml (450 words)

	Heart Arrhythmias and Long QT Syndrome
		Long QT syndrome refers to a condition in which there is an abnormally long QT interval on the electrocardiogram.
		It can be inherited ("congenital long QT") or induced by drugs or abnormal levels of the salts normally found in the blood, such as potassium and magnesium ("acquired long QT").
		Some people, despite having a normal QT interval under normal conditions, may develop a prolonged QT and associated rhythm abnormalities when taking certain medications; this tendency may also be inherited, and is the subject of our research effort.
	www.qtdrugs.org /info-center/QT-interval.htm (366 words)

	Long QT Syndrome: Adult Onset Genetic Disease Program at The University Hospital, Newark, NJ
		Long QT Syndrome is an autosomal dominant condition, and through mutation scanning (a blood test) geneticists can determine if and where there is a gene mutation.
		If Long QT Syndrome is known to occur in the family, a person should strongly consider having the genetic test.
		Because of its serious implications, it is particularly important for families with inherited Long QT Syndrome to discuss test results and their implications with an experienced genetic counselor along with a cardiologist with experience in Long QT Syndrome management, and to perhaps seek counseling support by a mental health professional.
	www.theuniversityhospital.com /adultgenetics/long.htm (417 words)

	Long QT syndrome - OhioHealth
		In some people with long QT syndrome, fainting spells are triggered by sudden bursts of adrenaline in the body, such as are experienced during intense exercise or emotional upset.
		In inherited long QT syndrome, the heart may be likened to a "ticking time bomb" and it's largely unknown whether the "bomb" is a dud or about ready to detonate with just the right (or wrong) trigger.
		Families with inherited long QT syndrome may find it helpful to talk to a cardiologist with expertise in diagnosing and treating long QT syndrome, a genetics counselor, a psychiatrist or psychologist as well as other families with the condition.
	www.ohiohealth.com /bodymayo.cfm?xyzpdqabc=0&id=6&action=detail&ref=1242 (3054 words)

	~Amanda's Web Site~ - Long Qt Syndrome
		Thus, in those with an elongated QT interval, sometimes referred to as "long QT syndrome," there is prolongation of the resting pause of the heart.
		Long QT syndrome may lead to irregular heart rhythms (arrhythmias), potentially resulting in a sudden loss of consciousness (or syncope) due to insufficient blood supply to the brain and sudden death.
		The principle abnormality to be identified is a prolonged QT interval relative to the heart rate, determined by an increase in the calculated QTc interval, and the appearance of bifidT-waves.
	myweb.ecomplanet.com /COAT1407/mycustompage0004.htm (2116 words)

	Long QT Syndrome - Recognizing the Signs and Symptoms
		Long QT syndrome often goes unnoticed in patients because it rarely presents easily recognizable symptoms.
		However, as high as 40% of people diagnosed with long QT syndrome are asymptomatic at the time of their diagnosis.
		Since over 75% of long QT syndrome carriers are identified through EKG analysis, it is critical that their EKG be evaluated properly.
	www.long-qt-syndrome.com /recognize_lqts.html (684 words)

	ALL ABOUT LONG QT SYNDROME
		The frequency of Long QT is unknown but it appears to be a common cause of sudden and unexplained death in children and young adults.
		The principal abnormality to be identified is a prolonged QT interval relative to the heart rate, determined by an increase in the calculated QTc interval, and the appearance of bifidT-waves.
		Long QT is commonly inherited by autosomal-dominant transmission.
	www.mydr.com.au /default.asp?Article=3063 (1757 words)

	eMedicine - Long QT Syndrome : Article Excerpt by: Ali A Sovari, MD
		Background: Long QT syndrome (LQTS) is a congenital disorder characterized by a prolongation of the QT interval on ECG and a propensity to ventricular tachyarrhythmias, which may lead to syncope, cardiac arrest, or sudden death.
		The QT interval on the ECG, measured from the beginning of the QRS complex to the end of the T wave, represents the duration of activation and recovery of the ventricular myocardium.
		QT intervals corrected for heart rate (QTc) longer than 0.44 seconds are generally considered abnormal, though a normal QTc can be slightly prolonged in female individuals (up to 0.46 sec).
	www.emedicine.com /med/byname/long-qt-syndrome.htm (623 words)

	BBC - Health - Ask the doctor - Long QT syndrome (Site not responding. Last check: 2007-11-03)
		Long QT syndrome is a rather unusual rhythm problem of the heart.
		People with long QT syndrome may have no symptoms at all and be perfectly healthy between attacks, when the QT interval may be normal.
		For a few whose long QT interval trips them into potentially deadly fibrillation of the ventricles, it's necessary to implant a special type of tiny defibrillator into the chest to shock them back into a normal rhythm.
	www.bbc.co.uk /health/ask_the_doctor/longqtsyndrome.shtml (775 words)

	Long QT Syndrome
		Long QT syndrome may be inherited from your parents.
		Inherited long QT syndrome is caused by defects on at least 6 genes.
		Long QT syndrome may also be a result of certain medications.
	www.mamashealth.com /syndrome/qt.asp (279 words)

	Long QT Syndrome: Chromosomal and Genetic Abnormalities: Merck Manual Home Edition
		Long QT syndrome is an abnormality of the heart's electrical system, (see Abnormal Heart Rhythms: Introduction) which may cause loss of consciousness or sudden death.
		In most adults, long QT syndrome is caused by use of a drug or a disorder.
		Some people with long QT syndrome are also born deaf.
	www.merck.com /mmhe/sec23/ch266/ch266i.html (341 words)

	What is Long QT Syndrome?
		Long QT syndrome is a disruption in the heart’s normal rhythms that can cause fainting during prolonged or strenuous activity, or during extreme excitation.
		Though long QT is quite rare, overlooking the possibility of its presence can lead to tragic consequences.
		When long QT has been undiagnosed, the best protection for children is to have trained professionals present who know how to use a portable defibrillator.
	www.wisegeek.com /what-is-long-qt-syndrome.htm (607 words)

	Long QT Syndrome
		Long QT Syndrome (LQTS) is a disorder of the electrical system that triggers the heartbeat, and regulates the muscle contractions that pump the body's blood supply.
		In Long QT Syndrome, the interval between Q and T is longer than normal.
		People with this syndrome are susceptible to an abnormally rapid heart rhythm (arrhythmia) called "torsade de pointes." When this occurs, the heart muscle cannot contract effectively, and the normal volume of blood is reduced to the body and - most important - to the brain.
	www.hrspatients.org /patients/heart_disorders/long_qt_syndrome.asp (576 words)

	Long QT syndrome - MayoClinic.com (Site not responding. Last check: 2007-11-03)
		Long QT syndrome (LQTS) is a disorder of the heart's electrical system.
		Treatment for long QT syndrome may involve limiting your physical activity, avoiding certain medications or taking medications to prevent the development of a chaotic heart rhythm.
		Some people with long QT syndrome also need an implantable device to control the heart's rhythm and prevent against sudden death.
	www.mayoclinic.com /health/long-qt-syndrome/DS00434 (216 words)

	QTsyndrome.ch - Stories Of The Heart
		We need to get the public and medical profession to learn about long QT syndrome, I think because long QT syndrome is supposed to be a rare heart condition, that most doctors think they wont come across it, and so choose to ignore that it is out there.
		While Kara was in the hospital with her newfound diagnosis of Long QT syndome, it was a remarkable coincidence that the genetic markers for some forms of LQT were found.
		The diagnosis eventually became Long QT syndrome and her hospitalization lasted four months with that time being divided among the special care unit, the cardiology unit, and the pediatric unit where she was a rehab patient.
	www.qtsyndrome.ch /stories.html (4266 words)

	Long QT Syndrome (Site not responding. Last check: 2007-11-03)
		Long QT syndrome (LQTS) is an inherited disease that affects sodium and potassium channels in the heart, leading to abnormal functioning in the heart's electrical system.
		In a postmortem investigation, her older sister was found to have a prolonged QT interval on resting electrocardiogram.
		Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate: implications for gene-specific therapy.
	www.arabmedmag.com /issue-31-01-2004/cardiology/main02.htm (2087 words)

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