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Topic: Loop diuretic


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In the News (Sun 12 Oct 08)

  
  Use of inhaled loop diuretics for treating allergen-induced nasal reactions - Patent 5392767
Loop diuretics, particularly their well known representative furosemide, are effective drugs for the treatment of allergen-induced nasal reactions, if a solution of the loop diuretic is nebulized into the nostrils.
Loop diuretics are for instance bumetanid, ethacrynic acid, etolozine or piretanide, torasemide, indacrinon, azosemide, besides furosemide.
To investigate whether furosemide, one of the typical representatives of the loop diuretics has a protective activity on the allergic reactions in the nasal mucosa a double-blind, placebo-controlled, randomized crossover study on the effect of inhaled furosemide on the response to nasal allergen challenge was performed.
www.freepatentsonline.com /5392767.html   (1366 words)

  
  Loop diuretic - Wikipedia, the free encyclopedia
Loop diuretics are diuretics that act on the ascending loop of Henle in the kidney.
Loop diuretics act on the Na-K-2Cl symporter in the thick ascending limb of the loop of Henle to inhibit sodium and chloride reabsorption.
Loop diuretics also cause vasodilation of the veins and of the kidney's blood vessels, mechanically causing a decrease in blood pressure.
en.wikipedia.org /wiki/Loop_diuretic   (489 words)

  
 GUIDELINE 12: USE OF DIURETICS IN CKD
Loop diuretics are primarily bound to albumin, which is reduced in patients with uremia and the nephrotic syndrome.
Diuretic resistance in CKD may be due to an independent cause of increased tubular reabsorption of sodium, such as nephrotic syndrome, heart failure, cirrhosis, or use of non-steroidal anti-inflammatory agents.
In patients with specific conditions causing increased sodium reabsorption, the response to a loop diuretic is attenuated in relationship to the severity of the underlying disease, and substantially higher doses of furosemide may be necessary to achieve a diuresis.
www.kidney.org /professionals/kdoqi/guidelines_bp/guide_12.htm   (5902 words)

  
 Diuretic - Wikipedia, the free encyclopedia
Diuretics also decrease the extracellular fluid (ECF) volume, and are primarily used to produce a negative extracellular fluid balance.
Some diuretics, such as acetazolamide, help to make the urine more alkaline and are helpful in increasing excretion of substances such as aspirin in cases of overdose or poisoning.
The antihypertensive actions of some diuretics (thiazides and loop diuretics in particular) are independent of their diuretic effect.
en.wikipedia.org /wiki/Diuretic   (379 words)

  
 Loop diuretics: from the Na-K-2Cl transporter to clinical use -- Shankar and Brater 284 (1): 11 -- AJP - Renal ...
limb of the loop of Henle (66, 69, 70).
response to loop diuretics in the edematous disorders is characterized
by displacing the diuretic from urinary albumin (56, 57).
ajprenal.physiology.org /cgi/content/full/284/1/F11   (6633 words)

  
 Medicines - Loop diuretics (e.g. furosemide/frusemide)
Loop diuretics are most commonly used to relieve the symptoms of heart failure, such as breathlessness, swollen feet and ankles, and tiredness.
The loop diuretics furosemide and bumetanide need to be taken with care in pregnancy or breastfeeding, while torasemide is not considered suitable.
Loop diuretics are usually taken first thing in the morning, and then sometimes in the early afternoon, so that the increased urine production they cause doesn't interfere with sleep.
www.bupa.co.uk /health_information/html/medicine/loop_diuretics.html   (862 words)

  
 Loop Diuretics   (Site not responding. Last check: 2007-09-19)
Loop diuretics are more potent than thiazide diuretics.
Loop diuretics are also used to reduce water accumulation caused by other diseases.
Loop diuretics and digitalis-containing products should only be used under the direct supervision of a doctor trained in their use.
www.kroger.com /hn/Drug/Loop_Diuretics.htm   (1170 words)

  
 [No title]
After sodium is passed on by the proximal tubule, loop diuretics act on it in the inside passage of the loop of Henle - thus the name "loop" diuretics.
Loop diuretic effectiveness is not just from the amount of drug that makes it to the kidney, but also from how long the drug stays there to do its thing.
The effectiveness of loop diuretics is also related to the amount of sodium in the kidney's loop of Henle.
www.chfpatients.com /text/diuretic_resistance.txt   (1289 words)

  
 Diuretics - diuretic medications
Diuretics - class of drugs that increase the volume of urine (diuresis) by promoting the excretion of salts (especially sodium and potassium) and water via the kidneys.
Diuretics are used to reduce the oedema due to salt and water retention in disorders of the kidneys, heart, or liver.
The use of diuretics can result in potassium deficiency; this is corrected by the simultaneous administration of a potassium supplement or by adding another diuretic with a potassium-sparing effect, such as amiloride or triamterene.
www.mecsinc.com /category-diuretics.htm   (200 words)

  
 Loop Diuretics - Patient UK   (Site not responding. Last check: 2007-09-19)
Loop diuretics are mainly used to treat heart failure.
Loop diuretics are a common treatment for heart failure.
Loop diuretics are also used to treat other conditions which cause fluid to build up in the body such as certain liver and kidney disorders.
www.patient.co.uk /showdoc/27000313   (620 words)

  
 diuretics
Because loop and thiazide diuretics increase sodium delivery to the distal segment of the distal tubule, this increases potassium loss (potentially causing hypokalemia) because the increase in distal tubular sodium concentration stimulates the aldosterone-sensitive sodium pump to increase sodium reabsorption in exchange for potassium and hydrogen ion, which are lost to the urine.
Because this class of diuretic has relatively weak effects on overall sodium balance, they are often used in conjunction with thiazide or loop diuretics to help prevent hypokalemia.
Potassium-sparing, aldosterone-blocking diuretics (e.g., spironolactone) are used in secondary hypertension caused by hyperaldosteronism, and sometimes as an adjunct to thiazide treatment in primary hypertension to prevent hypokalemia.
cvpharmacology.com /diuretic/diuretics.htm   (1823 words)

  
 loop - Search Results - MSN Encarta
The downtown area, known locally as the Loop (from the fact that it is encircled by elevated railway tracks), has been undergoing rapid change and...
Möbius Strip, surface that can be formed by taking a long, rectangular strip of paper, rotating the ends 180° with respect to one another, and...
Diuretic, chemical compound that increases the flow of urine and thus eliminates accumulations of water in cells, tissues, blood, and organs.
ca.encarta.msn.com /loop.html   (152 words)

  
 Diuretics - Drug Comparisons - Compare Drugs - DrugDigest
Diuretics work by increasing the amount of salt and water eliminated by the kidneys, thus reducing blood pressure and work load on the heart.
Diuretic treatment usually starts with low doses that are increased if necessary to increase urine output and reduce body weight.
Of the combination diuretics, all are typically taken once daily except for triamterene and hydrochlorothiazide which is taken once or twice daily.
www.drugdigest.org /DD/Comparison/NewComparison/0,10621,33-9,00.html   (917 words)

  
 10% Off Pet Diuretic Treatments - Spironolactone & Furosemide for Dogs and Cats
A diuretic is any drug that aids in ridding your pet's body of excess fluid, which can accumulate as a result of heart or lung disease.
Furosemide is a diuretic used in the treatment of congestive heart failure, pulmonary edema, kidney disease, high blood pressure and edema.
Spironolactone is a potassium sparing diuretic used in the treatment of congestive heart failure (CHF) and ascites (fluid in the abdomen).
www.fabuloussavings.com /online/us/petmedicine/2/diuretics   (350 words)

  
 MedlinePlus Drug Information: Diuretics, Loop (Systemic)   (Site not responding. Last check: 2007-09-19)
Loop diuretics are given to help reduce the amount of water in the body.
Loop diuretics may also be used for other conditions as determined by your doctor.
In general, diuretics are not useful for normal swelling of feet and hands that occurs during pregnancy.
www.nlm.nih.gov /medlineplus/druginfo/uspdi/202205.html   (2449 words)

  
 diuretic
Diuretics are useful in a number of conditions that may be related to total body water volume, peripheral resistance, or production of fluids within the body.
Loop diuretics are useful in the treatment of hyperkalaemia, as discussed below.
Loop diuretics (which result in a relatively high degree of potassium loss) may be used to lower mild hyperkalaemia.
faculty.swosu.edu /scott.long/phcl/diuretic.htm   (3607 words)

  
 Medscape Search: diuretic
Loop diuretics are a common class of drug used in the treatment of chronic conditions such as chronic heart failure (CHF) and renal failure.
Furosemide, a short-acting loop diuretic, may have a greater influence on heart rate variability and fluid balance than azosemide, a long-acting loop diuretic in patients with mild to moderate chronic congestive heart failure.
The objective of this study was to determine the impact of diuretics on the mortality rate of critically ill patients with acute renal failure.
search.medscape.com /uslclient/searchMedscape.do?queryText=diuretic   (911 words)

  
 Diuretics
Potassium wasting associated with diuretics is directly dependent on the amount of additional sodium retained in the tubule and the plasma concentration of aldosterone.
Osmotic diuretics are used primarily to reduce tissue (usually CNS or renal tubule) edema and to expand circulatory volume.
Loop diuretics produce a potent but short-lived diuresis that is not limited by dehydration.
education.vetmed.vt.edu /Curriculum/VM8784/diuretics.htm   (615 words)

  
 Use of diuretics in cardiovascular diseases: (1) heart failure -- Shah et al. 80 (942): 201 -- Postgraduate Medical ...
and hydrogen ions in the ascending loop of Henle.
Diuretics are the mainstay of therapy for symptomatic chronic
Diuretics and beta blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension.
pmj.bmjjournals.com /cgi/content/full/80/942/201   (2574 words)

  
 Intravenous or enteral loop diuretics for preterm infants with (or developing) chronic lung disease
An increase in phosphaturia is observed with all diuretics.
Diuretics are useful to treat pulmonary edema due to congestive heart failure and to treat systemic hypertension, a common complication of BPD.
Because of the long half-life of loop diuretics in immature infants, a prolonged washout period is required to eliminate all diuretic effect before initiating a study or between exposures in a cross-over study.
www.nichd.nih.gov /cochrane/brion2/brion.HTM   (11607 words)

  
 GearProfiles.com
It belongs to the group of saluretics and to be exact is a loop diuretic.
A very important characteristic which must be absolutely monitored with loop diuretics is the reabsorbtion of potassium ions, sodium ions, and chloride ions.
Extreme caution is advised when athletes who are already substantially drained and dehydrated continue their loop diuretic treatment with a "make it or die atti-tude," or even continue the intake altogether with a completely reduced liquid intake.
www.gearprofiles.com /lasix.php   (575 words)

  
 OhioLINK ETD: HAMED, EHAB
Loop diuretics offer great advantages in treating edematous states associated with congestive heart failure, liver cirrhosis and kidney failure owing to their intense diuretic effect.
Evidences suggested the diuretic effect can be exaggerated by careful control of the rate at which loop diuretics are made available to the urinary tubules.
While providing comparable diuretic and saliuretic effects to that of immediate release formulation, extended release bumetanide formulation can offer the advantage of avoiding the initial, unpleasant and intense diuretic effect experienced with immediate release formulations.
www.ohiolink.edu /etd/view.cgi?ucin1037205224   (338 words)

  
 Numark | Loop Diuretics
Digitalis refers to a family of plants commonly called foxglove that contain digitalis glycosides, chemicals with actions and toxicities similar to the prescription drug digoxin.
Liquorice may enhance the side effects of potassium-depleting diuretics, including loop diuretics.
Loop diuretics and liquorice should be used together only under careful medical supervision.
www.numarkpharmacists.com /hn/Drug/Loop_Diuretics.htm   (1249 words)

  
 Mechanisms and management of diuretic resistance in congestive heart failure -- De Bruyne 79 (931): 268 -- Postgraduate ...
of diuretic resistance in the heart failure population is unknown.
thereby antagonise the natriuretic response to loop diuretics.
Diuretic efficacy of high dose furosemide in severe heart failure: bolus injection versus continuous infusion.
pmj.bmjjournals.com /cgi/content/full/79/931/268   (2444 words)

  
 A diuretic that is not from the sulphur compound
A diuretic that is not from the sulphur compound
Thiazide and spironolactone containing diuretics should not be used, and other thiazides-like drugs such as amiloride, chlorthalidone, xipamide, triamterene and acetazolamide are best avoided where a patient is allergic to sulphonamide (sulpha) drugs.
Another loop diuretic, Burinex (bumetanide), does not have this contraindication listed in the comprehensive database I looked it up in, so it should be OK, but the loop diuretic Torem (torasemide) should not be taken by patients who are hypersensitive to sulphonylureas, which are used to lower blood glucose in diabetes.
www.netdoctor.co.uk /ate/diabetes/201550.html   (376 words)

  
 Failure of the Loop Diuretic Torasemide to Improve Renal Function of Hypoxemic Vasomotor Nephropathy in the Newborn ...   (Site not responding. Last check: 2007-09-19)
Failure of the Loop Diuretic Torasemide to Improve Renal Function of Hypoxemic Vasomotor Nephropathy in the Newborn Rabbit -- DUBOURG et al.
Eades SK, Christensen ML 1998 The clinical pharmacology of loop diuretics in the pediatric patient.
Shilliday IR, Quinn KJ, Allison MEM 1997 Loop diuretics in the management of acute renal failure: a prospective, double blind, placebo-controlled, randomized study.
www.pedresearch.org /cgi/content/full/47/4/504   (2960 words)

  
 Upregulation of Na+ transporter abundances in response to chronic thiazide or loop diuretic treatment in rats -- Na et ...
Therefore, this study was undertaken to elucidate the molecular basis of the adaptive mechanisms in long-term use of diuretics.
to chronic infusion of a loop diuretic (furosemide) or a thiazide
Loop diuretic infusion increases thiazide-sensitive Na /Cl -cotransporter abundance: role of aldosterone.
ajprenal.physiology.org /cgi/content/full/284/1/F133   (5345 words)

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