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Topic: Lymphadenopathy

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	Epidemiologic Notes and Reports Persistent, Generalized Lymphadenopathy among Homosexual Males
		There are many known causes of generalized lymphadenopathy including viral infections (e.g., hepatitis B, infectious mononucleosis, cytomegalovirus infection, rubella), tuberculosis, disseminated Mycobacterium avium-intracellulare, syphilis, other bacterial and fungal infections, toxoplasmosis, connective tissue disorders, hypersensitivity drug reactions, heroin use, and neoplastic diseases (including leukemia and lymphoma) (2).
		Although these cases have been identified and defined on the basis of the presence of lymphadenopathy, this finding may be merely a manifestation of an underlying immunologic or other disorder that needs to be characterized further.
		An analysis of trends in incidence for lymphadenopathy over the past several years is being conducted to determine whether this syndrome is new and whether homosexual males are particularly affected.
	www.cdc.gov /mmwr/preview/mmwrhtml/00001096.htm (916 words)

	Lymphadenopathy
		Since lymphadenopathy can be associated with a wide range of disorders spanning relatively benign medical problems such as streptococcal pharyngitis to life-threatening diseases such as malignancies, the discovery of enlarged nodes represents an important physical finding that demands a systematic evaluation.
		Lymphadenopathy may represent an increase in the number and size of lymphoid follicles with proliferation of lymphocytes as a response to a new antigen.
		Immunologic conditions that cause lymphadenopathy can be secondary to clearly identified antigens, as in serum sickness, or a response to an insect bite, or the lymphadenopathy may be secondary to antigenic stimulation in conditions where the antigen has not been identified.
	www.ncbi.nlm.nih.gov /books/bv.fcgi?rid=cm.chapter.4456 (2506 words)

	Lymphadenopathy and AIDS- New Treatments, May 2, 2008
		Lymphadenopathy may be the only clinical finding or one of several nonspecific findings, and the discovery of swollen lymph nodes will often raise the specter of serious illness such as lymphoma, acquired immunodeficiency syndrome or metastatic cancer or AIDS associated swollen glands.
		Lymphadenopathy refers to nodes that are abnormal in either size, consistency or number.
		Because generalized lymphadenopathy almost always indicates that a significant systemic disease is present, the clinician should consider the diseases listed in Table 4 and proceed with specific testing as indicated.
	www.medical-library.org /journals2a/Lymphadenopathy2.htm (498 words)

	Lymphadenopathy: Differential Diagnosis and Evaluation - October 15, 1998 - American Academy of Family Physicians
		he cause of lymphadenopathy is often obvious: for example, the child who presents with a sore throat, tender cervical nodes and a positive rapid strep test, or the patient who presents with an infection of the hand and axillary lymphadenopathy.
		Lymphadenopathy may be the only clinical finding or one of several nonspecific findings, and the discovery of swollen lymph nodes will often raise the specter of serious illness such as lymphoma, acquired immunodeficiency syndrome or metastatic cancer.
		A subset of patients will either have unexplained lymphadenopathy after the initial clinical evaluation or have a presumptive diagnosis that is made in the "diagnostic" or "suggestive" branches of the algorithm and is not confirmed by test results or by the clinical course.
	www.aafp.org /afp/981015ap/ferrer.html (2998 words)

	Lymphadenopathy - Lucile Packard Children's Hospital
		Lymphadenopathy is the term for swelling of the lymph nodes - the bean-shaped organs found in the underarm, groin, neck, chest, and abdomen that act as filters for the lymph fluid as it circulates through the body.
		Lymphadenopathy can occur in just one area of the body, such as the neck, or it may be generalized, with lymph node enlargement in several areas.
		In addition to a complete medical history and physical examination, diagnostic procedures for lymphadenopathy may include a lymph node biopsy in which a sample of tissue is removed from the lymph node and examined under a microscope.
	www.lpch.org /diseaseHealthInfo/HealthLibrary/ent/lymphpathy.html (587 words)

	Mayo Clinic Proceedings
		Lymphadenopathy may be a part of a complex case presentation, or the clinical cause may be straightforward.
		Lymphadenopathy is common and affects patients of all ages.
		The differential diagnosis of lymphadenopathy of unknown origin is similar to that of fever of unknown origin or an elevated erythrocyte sedimentation rate, in that most cases are due to an infection, a malignancy, or an immune disorder.
	www.mayoclinicproceedings.com /inside.asp?AID=1493&UID= (5133 words)

	Generalised Lymphadenopathy - Patient UK
		Lymphadenopathy is one of the most common clinical problems encountered in paediatrics.
		For proper assessment of generalised lymphadenopathy it is necessary to familiarise oneself with what is normal at a particular age.
		Superior vena cava syndrome - insidious compression of the superior vena cava (SVC) from mediastinal lymphadenopathy, presenting with cough, wheezing and respiratory tract obstruction.
	www.patient.co.uk /showdoc/40000271 (1802 words)

	CIGNA - Lymphadenopathy, Angioimmunoblastic with Dysproteinemia
		Angioimmunoblastic Lymphadenopathy with Dysproteinemia (AILD) is a progressive immune system disorder possibly caused by viral infections, chronic stimulation of immune responses or drug treatments prescribed for other conditions.
		Angioimmunoblastic Lymphadenopathy with Dysproteinemia (AILD) is characterized by acute onset with fever, chills, sweating, general discomfort, weight loss, and/or skin rashes.
		Dermatopathic Lymphadenopathy, also known as Lipomelanic Reticulosis, is characterized by lymph node enlargement with over-production of cells known as histiocytes and macrophages containing fat and the fl pigment known as melanin.
	www.cigna.com /healthinfo/nord439.html (1059 words)

	eMedicine - Angioimmunoblastic Lymphadenopathy With Dysproteinemia : Article by Noah S Scheinfeld
		AILD is a type of peripheral T-cell lymphoma that is clinically characterized by high fever and generalized lymphadenopathy that sometimes has cutaneous involvement.
		A deletion mutant of the LMP1 oncogene of EBV is associated with the evolution of angioimmunoblastic lymphadenopathy into B immunoblastic lymphoma.
		For example, immunoblastic lymphadenopathy presented as an acute abdomen and mixed bacteremia with Eikenella corrodens and group C streptococci infection.
	www.emedicine.com /derm/topic932.htm (4110 words)

	Assessing Lymphadenopathy - Patient UK
		Assessing Lymphadenopathy - Patient UK PatientPlus articles are written for doctors and so the language can be technical.
		The cause of lymphadenopathy is often obvious and is usually a result of benign infectious causes.
		Localized lymphadenopathy should prompt a search for an adjacent precipitating lesion and an examination of other nodal areas to rule out generalised lymphadenopathy.
	www.patient.co.uk /showdoc/40001828 (786 words)

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