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Topic: Lymphoblastic lymphoma

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	Lymphoblastic lymphoma : Cancerbackup
		Lymphoblastic lymphoma is a very rare form of non-Hodgkin lymphoma in adults, accounting for less than 3 in 100 cases overall.
		Lymphoblastic lymphoma is very similar to the condition acute lymphoblastic leukaemia (ALL).
		New treatments for lymphoblastic lymphoma are being researched all the time, and you might be invited by your doctor to take part in a clinical trial to compare a new treatment against the best available standard treatment.
	www.cancerbackup.org.uk /Cancertype/Lymphomanon-Hodgkin/TypesofNHL/Lymphoblastic (1124 words)

	Lymphoma - Wikipedia, the free encyclopedia
		Lymphoma is a variety of cancer that originates in lymphocytes or, more rarely, of histiocytes.
		Lymphomas are part of the broad group of diseases called hematological neoplasms.
		Traditionally, Lymphoma is classified as Hodgkin's lymphoma, discovered by Thomas Hodgkin in 1832, and non-Hodgkin's lymphoma (all other types of lymphoma).
	en.wikipedia.org /wiki/Lymphoma (511 words)

	ACS :: What Is Non-Hodgkin Lymphoma in Children?
		Lymphomas are most often classified by how the cancer cells look under the microscope (their size and shape) and their pattern of growth within the lymph node.
		Most cases of lymphoblastic lymphoma develop from T cells in the thymus and form a mass in the anterior mediastinum (the area behind the breast bone).
		Lymphoblastic lymphoma can spread very quickly to the bone marrow, other lymph nodes, the surface of the brain, and/or the membranes that surround the lungs and heart.
	www.cancer.org /docroot/CRI/content/CRI_2_4_1x_What_is_childhood_non_Hodgkins_lymphoma_9.asp (1760 words)

	HON Mother & Child Glossary, Childhood Cancers: Lymphoma
		Lymphoma is divided into Hodgkin's disease (or Hodgkin's lymphoma) and non-Hodgkin's disease.
		The most common symptom of lymphoma is a painless swelling in the lymph nodes in the neck, underarm, or groin.
		Lymphoma risk increases with decreasing immune function, such as that caused by acquired immune deficiency syndrome (AIDS) or exposure to certain infectious agents.
	www.hon.ch /Dossier/MotherChild/child_cancer/cancer_lymphoma.html (502 words)

	Lymphoma Information Network - Lymphoblastic Lymphoma
		Lymphoblastic lymphoma is a form of lymphoma which occurs mainly in children and adolescents, where it accounts for about half of childhood lymphomas.
		Under the newest WHO lymphoma classification, lymphoblastic lymphoma is either determined to be a precursor T cell neoplasm or a precursor B cell neoplasm depending on the type of lymphatic cells that are cancerous.
		The chief biologic difference is that lymphoblastic leukemias are predominantly B-cell diseases, unlike the extra-medullary, mostly T-cell lymphoblastic lymphomas.
	www.lymphomainfo.net /nhl/types/lbl.html (352 words)

	Lymphoblastic Lymphoma
		The significance of CD79a coexpression in T-cell lymphoblastic lymphoma and the association between lymphoblastic lymphoma and Langerhans cell histiocytosis are discussed.
		Lymphoblastic lymphoma is a neoplasm of precursors lymphoid cells morphologically indistinguishable from those of acute lymphoblastic leukemia.
		Because the differential diagnosis of ES and lymphoblastic lymphoma can be difficult and the differential diagnostic value of leukocyte antigens and immunoglobulin heavy chain gene rearrangement studies have not been fully evaluated, we conducted a more extensive investigation on 33 (21 soft tissue and 12 intraosseous) ES cases.
	www.thedoctorsdoctor.com /diseases/lymphoma_lymphoblastic.htm (2245 words)

	Childhood Non-Hodgkin's Lymphoma: (Site not responding. Last check: 2007-10-23)
		Lymphoma (Hodgkin's and non-Hodgkin's) is the third most common childhood malignancy, and non-Hodgkin's lymphoma (NHL) accounts for approximately 7% of cancers in children less than 20 years of age.
		Lymphoblastic lymphomas are usually positive for the enzyme terminal deoxynucleotidyl transferase (TdT) and have a T-cell immunophenotype.
		Patients with lymphoblastic lymphoma with >25% malignant cells in the bone marrow are usually considered to have leukemia and may be appropriately treated on leukemia clinical trials.
	www.acor.org /cnet/62808.html (8598 words)

	Childhood Non-Hodgkin's Lymphoma Treatment - National Cancer Institute
		While lymphomas in adults are more commonly of low or intermediate grade, almost all that occur in children are high grade and can be classified into 1 of 4 categories: (1) lymphoblastic lymphomas; (2) Burkittâs and Burkittâs-like lymphoma/small noncleaved B-cell lymphoma; (3) diffuse large cell lymphomas (B T null); and (4) anaplastic large cell lymphoma.
		Nearly 75% of patients with lymphoblastic lymphoma have an anterior mediastinal mass and may present with symptoms of dyspnea, wheezing, stridor, dysphagia, or swelling of the head and neck.
		About 10% to 15% of lymphoblastic lymphomas have non-T immunologic characteristics (for example, common acute lymphocytic leukemia antigen [CD10]-positive precursor B-cell phenotype).[3] Chromosomal abnormalities are not well characterized in patients with lymphoblastic lymphoma.
	www.nci.nih.gov /cancertopics/pdq/treatment/child-non-hodgkins/HealthProfessional/page2 (1295 words)

	Lymphoma, non-Hodgkin's, childhood: Treatment - Health Professional Information [NCI PDQ] - SJMMC, Ann Arbor, Michigan ...
		Lymphoma (Hodgkin’s and non-Hodgkin’s) is the third most common childhood malignancy, and non-Hodgkin’s lymphoma (NHL) accounts for approximately 7% of cancers in children less than 20 years of age.[2,3] In the United States, there are about 800 new cases of NHL diagnosed each year.
		CNS disease in lymphoblastic lymphoma is defined by criteria similar to that used for acute lymphocytic leukemia, i.e., white blood cell count 5/µL or greater with malignant cells.
		Patients with stage III or stage IV lymphoblastic non-Hodgkin’s lymphoma have long-term survival rates from 75% to 90% as reported by the German Cooperative Group (BFM).[1,2,3] Because of the complexities of optimal therapeutic regimens, and the possibility of toxic side effects, patients should be offered the opportunity to enter into a clinical trial.
	www.sjmercyhealth.org /14426.cfm (5952 words)

	Childhood non-Hodgkin's lymphoma
		While lymphomas in adults are more commonly of low or intermediate grade, almost all that occur in children are high grade and can be classified into 1 of 4 categories: 1) Burkitt's and Burkitt's-like lymphoma/small noncleaved B cell lymphoma; 2) lymphoblastic lymphomas; 3) diffuse large cell lymphomas (B,T,null); and 4) anaplastic large cell lymphoma.
		In stage II non-Hodgkin's lymphoma, disease extent is a single tumor with regional node involvement, two or more tumors or nodal areas on one side of the diaphragm, or a primary gastrointestinal tract tumor (resected) with or without regional node involvement.
		Patients with lymphoblastic lymphoma with greater than 25% malignant cells in the bone marrow are usually considered to have leukemia and may be appropriately treated on leukemia clinical trials.
	cancerweb.ncl.ac.uk /cancernet/100915.html (6325 words)

	Similar Outcomes of Autologous or Allogeneic Transplants for Lymphoblastic Lymphoma
		Lymphoblastic lymphoma is a subset of non-Hodgkin's lymphoma (NHL) which has many of the characteristics of acute lymphoblastic leukemia (ALL), including bone marrow and central nervous system involvement.
		Lymphoblastic lymphoma is relatively rare comprising 2% of all cases of NHL and occurs predominantly in male young adults.
		This study does not address the issue of whether patients with lymphoblastic lymphoma should receive a transplant in first remission or reserve this therapy for only those who relapse ie approximately 50% of patients.
	professional.cancerconsultants.com /oncology_nhl_news.aspx?id=29652 (897 words)

	Childhood T-Cell Lymphoblastic Lymphoma: Intensive Chemotherapy Is Effective, Without Use of High-Dose Radiation Therapy
		T-cell lymphoblastic lymphoma (T-LBL), a type of cancer of the blood, is the most common childhood lymphoma.
		Childhood T-cell lymphoblastic lymphoma is a type of non-Hodgkin’s lymphoma, or cancer of the blood, that can occur in children.
		Because relapses of lymphoma often occur in the brain, moderate doses of radiation therapy to the head were used preventatively.
	patient.cancerconsultants.com /nhl_cancer_news.aspx?id=18390 (538 words)

	Lymphoblastic Lymphoma - My Child Has - Children's Hospital Boston
		Lymphoblastic lymphoma is a type of non-Hodgkin's lymphoma, a cancer in the lymphatic system.
		Most cases of lymphoblastic lymphoma involve the T-cells in the thymus, and usually become evident with a mass in the chest and swollen lymph nodes.
		Lymphoblastic lymphoma tends to spread quickly to the bone marrow, lymph nodes, and sometime, to the surface of the brain and the membranes that surround the lungs and heart.
	www.childrenshospital.org /az/Site1258/mainpageS1258P0.html (1721 words)

	eMedicine - Lymphoma, Lymphoblastic : Article by Joseph M Tuscano, MD
		Background: Lymphoblastic leukemias/lymphomas are neoplasms of precursor T cells and B cells, or lymphoblasts.
		In 30-50% of patients, the lymphoblasts infiltrate bone marrow, causing ineffective hematopoiesis.
		Admit patients with lymphoblastic lymphoma (LBL) for neutropenic fever, symptomatic anemia, or thrombocytopenia.
	www.emedicine.com /med/topic1364.htm (3991 words)

	NCI: Childhood Non-Hodgkinâs Lymphoma
		Childhood non-Hodgkin’s lymphoma is a disease in which malignant (cancer) cells form in the lymph system.
		In stage I childhood non-Hodgkin’s lymphoma, cancer is found in a single area or lymph node outside of the abdomen or chest.
		In stage IV childhood non-Hodgkin’s lymphoma, cancer is found in the bone marrow, brain, or spinal cord.
	www.jamesline.com /cancertypes/listing/index.cfm?action=Display&ID=258002 (3098 words)

	Lymphoblastic Lymphoma
		Lymphoma is a general term for malignancies of lymphocytes or, more rarely, of histiocytes.
		Mimi was diagnosed 10 days later with T cell lymphoblastic lymphoma, which is hard to fight because it started in the lymph nodes rather than bone marrow.
		Diagnosed with lymphoblastic lymphoma on November 22, Rachel was noticeably coughing from more than a simple cold before parents Brenda and Ken Young took her...
	health.mongabay.com /cancer/Lymphoblastic_Lymphoma.html (1158 words)

	Non-Hodgkin's lymphoma (Site not responding. Last check: 2007-10-23)
		Non-Hodgkin's lymphomas are cancers of lymphoid tissue (lymph nodes, spleen, and other organs of the immune system).
		For most patients, the cause is unknown, but lymphomas may develop in people with suppressed immune systems as a result of organ transplantation, for instance.
		Burkitt's tumor is an example of a high-grade lymphoma.
	www.healthscout.com /ency/1/000581.html (221 words)

	Lymphoblastic lymphoma : Cancerbackup
		In ALL, the abnormal lymphocytes are mainly in the blood and bone marrow, whereas in lymphoblastic lymphoma they are generally in the lymph nodes or thymus gland.
		The upper half of the body is above the sheet of muscle underneath the lungs (the diaphragm), and the lower half is below the diaphragm.
		Stage 3 Lymphoma is present in lymph nodes in both the upper and lower parts of the body (ie in lymph nodes both above and below the diaphragm).
	www.cancerbackup.org.uk /Cancertype/Lymphomanon-Hodgkins/TypesofNHL/Lymphoblastic (1124 words)

	Adult non-Hodgkin's lymphoma
		Other types of aggressive non-Hodgkin's lymphoma are anaplastic large-cell lymphoma, adult T-cell lymphoma/leukemia, mantle cell lymphoma, intravascular lymphomatosis, angioimmunoblastic T-cell lymphoma, angiocentric lymphoma, intestinal T-cell lymphoma, primary mediastinal B-cell lymphoma, peripheral T- cell lymphoma, lymphoblastic lymphoma, post-transplantation lymphoproliferative disorder, true histiocytic lymphoma, primary central nervous system lymphoma, and primary effusion lymphoma.
		To treat certain types of non-Hodgkin's lymphoma that spread to the brain, chemotherapy may be put into the fluid that surrounds the brain through a needle in the brain or back (intrathecal chemotherapy).
		Treatment of adult non-Hodgkin's lymphoma depends on the stage of the disease, the histology and grade of the disease, and the patient's age and general health.
	cancerweb.ncl.ac.uk /cancernet/200066.html (2857 words)

	Runx1 deficiency predisposes mice to T-lymphoblastic lymphoma.
		In order to examine the hypothesis that decreased gene dosage of RUNX1 may be a critical event in the development of leukemia, we treated chimeric mice generated from Runx1(lacZ/lacZ) embryonic stem (ES) cells that have homozygous disruption of the Runx1 gene with N-ethyl-N-nitrosurea (ENU).
		We observed an increased incidence of T-lymphoblastic lymphoma in Runx1(lacZ/lacZ) compared to wild-type chimeras, and confirmed that the tumors were of ES cell origin.
		Our results therefore suggest that deficiency of Runx1 can indeed predispose mice to hematopoietic malignancies.
	acutemyeloidleukemia.researchtoday.net /archive/2/7/129.htm (227 words)

	Lymphoblastic Lymphoma (Site not responding. Last check: 2007-10-23)
		B lymphoblastic lymphoma accounts for 40 % of adult and 40% of all childhood lymphomas
		T lymphoblastic lymphoma accounts for 5 % of adult and 20% of all childhood lymphomas
		As general indicators B cell types have better prognosis than T cell types; also the more immature the B cell precursor was when maturation arrested and it became abnormal the better the prognosis.
	www.mcevoy.demon.co.uk /Medicine/Pathology/Haematology/WBC_Diseases/LblastLoma.html (245 words)

	Lymphoma Symptoms, Signs and Pictures : Doctor-Reviewed Information at Healthline.com
		Hodgkin's lymphoma is a malignancy (cancer) of lymph tissue found in the lymph nodes, spleen, liver, and bone marrow.
		A brain lymphoma is a type of malignancy (cancer).
		Burkitt lymphoma is a lymph gland tumor classified as a non-Hodgkin's type of lymphoma.
	www.healthline.com /channel/lymphoma.html (405 words)

	What Are The Different Types Of Lymphoma?
		In most cases the type of lymphoma is less important than the grade and stage of a particular lymphoma.
		Many types of lymphoma have traits that overlap with one another so it is often difficult to group them into definite categories.
		Burkitt's lymphoma is also seen in other parts of the world, but in most of these cases a virus doesn't seem to be involved.
	www.ehealthmd.com /library/lymphoma/NHL_types.html (699 words)

	Lymphoma, non-Hodgkin's, childhood: Treatment - Health Professional Information [NCI PDQ] -- Recurrent Childhood ... (Site not responding. Last check: 2007-10-23)
		Levine JE, Harris RE, Loberiza FR Jr, et al.: A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma.
		Kobrinsky NL, Sposto R, Shah NR, et al.: Outcomes of treatment of children and adolescents with recurrent non-Hodgkin's lymphoma and Hodgkin's disease with dexamethasone, etoposide, cisplatin, cytarabine, and l-asparaginase, maintenance chemotherapy, and transplantation: Children's Cancer Group Study CCG-5912.
		Gentet JC, Patte C, Quintana E, et al.: Phase II study of cytarabine and etoposide in children with refractory or relapsed non-Hodgkin's lymphoma: a study of the French Society of Pediatric Oncology.
	www.webmd.com /hw/nonhodgkins_lymphoma/ncicdr0000062808-recurrent-childhood-lymphoblastic-lymphoma.asp (410 words)

	MedlinePlus Medical Encyclopedia: Non-Hodgkin's lymphoma
		Non-Hodgkin's lymphomas can be slow-growing (low-grade) or rapidly growing (high-grade) cancer.
		The average survival is 6 to 8 years for patients with low-grade lymphoma.
		The outcome for patients with high-grade lymphoma depends upon the response to chemotherapy or other treatment, and the type of high-grade lymphoma.
	www.nlm.nih.gov /medlineplus/ency/article/000581.htm (551 words)

	Childhood Non-Hodgkin's Lymphoma: (Site not responding. Last check: 2007-10-23)
		The specific type of lymphoma is determined by how the cells look under a microscope.
		In stage I childhood non-Hodgkin's lymphoma, cancer is found in a single area or lymph node outside of the abdomen or chest.
		In stage IV childhood non-Hodgkin's lymphoma, cancer is found in the bone marrow, brain, or spinal cord.
	www.acor.org /cnet/258002.html (3951 words)

	Lymphoma, non-Hodgkin's, childhood: Treatment - Health Professional Information [NCI PDQ] -- Stage I and II Childhood ... (Site not responding. Last check: 2007-10-23)
		Overall survival is greater than 80% with aggressive leukemia-like therapy.[1,2,3,4] A clinical trial to address duration of therapy compared 9 weeks of doxorubicin, cyclophosphamide, vincristine, prednisone (CHOP) chemotherapy with 9 weeks of CHOP chemotherapy plus 24 weeks of maintenance therapy.
		Hvizdala EV, Berard C, Callihan T, et al.: Lymphoblastic lymphoma in children--a randomized trial comparing LSA2-L2 with the A-COP+ therapeutic regimen: a Pediatric Oncology Group Study.
		Lymphoma, non-Hodgkin's, childhood: Stage I and II Childhood Lymphoblastic Lymphoma
	www.webmd.com /hw/nonhodgkins_lymphoma/ncicdr0000062808-stage-i-and-ii-childhood-lymphoblastic-lymphoma.asp (407 words)

	My Online Lymphoblastic Lymphoma Journal Index
		Lymphoblastic Lymphoma is an acute (sudden onset) type of leukemia; while it affects children primarily, it is not unheard of for an adult to contract it.
		Leukaemia of the lymphoid cells is called acute lymphoblastic (lymphphatic) leukemia.
		I was diagnosed with the T-cell form of this cancer in October, 2002.
	www.geocities.com /lymphomafighter (276 words)

	Medical Dictionary: Lymphoblastic lymphoma - WrongDiagnosis.com
		Lymphoblastic lymphoma is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Lymphoblastic lymphoma, or a subtype of Lymphoblastic lymphoma, affects less than 200,000 people in the US population.
		They list Lymphoblastic lymphoma as a "rare disease".
	www.wrongdiagnosis.com /medical/lymphoblastic_lymphoma.htm (189 words)

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