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	Lymphoma Information Network - Follicular Lymphomas
		This lymphoma is rich in small-cleaved cells, which know how to voyage in the blood and are often found there as well as in the marrow and liver.
		Though these lymphomas are also indolent (low grade in the Working Formulation), the increased percentage of large cells is associated with a reduced average survival.
		Large-cell follicular lymphoma is classified as an intermediate-grade lymphoma, and the patients may benefit from the inclusion of an anthracycline in their chemotherapy.
	www.lymphomainfo.net /nhl/follicular.html (737 words)

	Lymphoma - Wikipedia, the free encyclopedia
		Lymphoma is a variety of cancer that originates in lymphocytes or, more rarely, of histiocytes.
		Lymphomas are part of the broad group of diseases called hematological neoplasms.
		Traditionally, Lymphoma is classified as Hodgkin's lymphoma, discovered by Thomas Hodgkin in 1832, and non-Hodgkin's lymphoma (all other types of lymphoma).
	en.wikipedia.org /wiki/Lymphoma (529 words)

	Hematopathology: Diffuse Large B-Cell Lymphomas (Site not responding. Last check: 2007-10-29)
		Aggressive histology means that many of the lymphoma cells are highly atypical: large and irregular, with vesicular nuclei and prominent nucleoli.
		Diffuse mixed lymphomas may originate from follicular center cells (by the way, low grade follicular lymphoma has a slightly different name that includes the word "cleaved": follicular small-cleaved and large cell).
		Another soft indication of a follicular center cell origin (and perhaps transformation from a folliclar lymphoma) is the presence of small-cleaved cells interspersed among the large cells (images).
	pleiad.umdnj.edu /hemepath/diffuse_large/diffuse_large.html (528 words)

	Mantle Cell Lymphoma
		Mantle cell lymphoma (MCL) is a distinct type of non-Hodgkin's lymphoma (NHL) characterized by the t(11;14)(q13;q32), in which the ccnd1 gene is juxtaposed with the immunoglobulin heavy chain gene, resulting in up-regulation of cyclin D1.
		Mantle cell lymphoma (MCL) is a B-cell neoplasm with a relatively aggressive clinical course.
		Mantle cell lymphoma (MCL) is a distinct clinicopathologic entity of non-Hodgkin's lymphoma, characterized by a monotonous proliferation of small to medium-sized lymphocytes with co-expression of CD5 and CD20, an aggressive and incurable clinical course, and frequent t(11;14)(q13;q32) translocation.
	www.thedoctorsdoctor.com /diseases/lymphoma_mantlecell.htm (10310 words)

	Lymphoma, Mantle-Cell - Lymphocytic Lymphoma, Diffuse, Poorly-Differentiated - information page with HONselect
		Broader term(s): - Lymphoma, Diffuse - Lymphoma, Non-Hodgkin - Lymphoma - Neoplasms
		Broader term(s): - Lymphoma, Non-Hodgkin - Lymphoma - Neoplasms
		Bevacizumab + CHOP-Rituximab in Untreated Mantle Cell Lymphoma
	www.hon.ch /HONselect/RareDiseases/EN/C04.557.386.480.300.725.500.html (368 words)

	Adult non-Hodgkin's lymphoma
		Splenic marginal zone lymphoma is an indolent lymphoma that is marked by massive splenomegaly and peripheral blood and bone marrow involvement, usually without adenopathy.[50,51] This type of lymphoma is otherwise known as splenic lymphoma with villous lymphocytes, an uncommon variant of B-cell chronic lymphocytic leukemia.
		Diffuse large B-cell lymphoma is the most common of the non-Hodgkin's lymphomas, comprising 30% of newly-diagnosed cases.[7] Most patients present with rapidly enlarging masses, often with symptoms both locally and systemically (designated B symptoms with fever, recurrent night sweats, or weight loss).
		Burkitt's lymphoma/diffuse small noncleaved cell lymphoma typically involves younger patients and represents the most common type of pediatric non-Hodgkin's lymphoma.[129] These aggressive extranodal B-cell lymphomas are characterized by translocation and deregulation of the c-myc gene on chromosome 8.
	cancerweb.ncl.ac.uk /cancernet/100066.html (14061 words)

	Malignant Lymphoma Diffuse Small Cell of the Lymph Node
		Malignant Lymphoma Diffuse Small Cell of the Lymph Node
		•Grossly, in common with all lymphomas, the affected gland is enlarged and appears firm and homogenous in consistency.
		•Histologically, the node architecture is replaced by uniform small cells which are apparently composed entirely of a nucleus with little cytoplasm.
	radiology.uchc.edu /eAtlas/HEM/1875.htm (235 words)

	Prognostic Factors in HIV-Related Diffuse Large-Cell Lymphoma: Before Versus After Highly Active Antiretroviral Therapy (Site not responding. Last check: 2007-10-29)
		The diagnostic criteria used to determine lymphoma subtype were based on the Lukes and Collins classification system for malignant lymphomas.17 Thus, for this study, the Lukes and Collins diffuse large cleaved, large noncleaved, and B immunoblastic subtypes were considered as DLCL.
		Differences in baseline lymphoma characteristics and HIV-related characteristics between the patients treated in the HAART and pre-HAART eras were compared using the t test or 2 test for continuous or categoric variables, respectively.
		Although both HIV-related (CD4 cell count) and lymphoma-related (attainment of complete remission and IPI score) factors were independently predictive of survival in the pre-HAART era, only lymphoma-related factors were independently prognostic for survival in the HAART era.
	www.hivdent.org /medical/medPFHR1105.htm (2353 words)

	BCL2 Overexpression Associated With Chromosomal Amplification in Diffuse Large B-Cell Lymphoma -- Monni et al. 90 (3): ...
		In contrast, the role of gene amplification in activation of oncogenes in non-Hodgkin's lymphomas is poorly characterized.
		The translocation is found in 70% to 85% of follicular lymphomas and in 20% to 30% of diffuse large-cell lymphomas.
		Lymphoma with t(14; 18) translocation was used as a positive control (P) and cases with loss of 18 (gels I and II) and normal 18 (gel III) were used as negative controls (N).
	www.bloodjournal.org /cgi/content/full/90/3/1168 (5226 words)

	2002 Educational Forum on Lymphoma Aggressive NHL: Diffuse Large B-Cell, Lymphoblastic, Burkitt's
		It may be that the patients with grade 3a follicular center cell lymphoma fit perhaps better into the low grade categories, those with grade 3b into the high grade category.
		For example, in recurrent large cell lymphoma, if we use this, that's as compared to using, say, ESHAP chemotherapy for six cycles or six months or DHAP or whatever chemotherapy regimen that people actually have to go through for a long period of time.
		There is a study in the central nervous system lymphomas, which are commonly associated with EB virus, and this is the marker for EB virus here, where people are using drugs like ganciclovir, which is an antiviral drug, to treat these lymphomas.
	www.hairlossadvisor.com /hairlossadvisor/12815.htm (10909 words)

	Lymphoma Information Network - Mantle Cell Lymphoma
		Mantle cell lymphoma (MCL) is a B-cell lymphoma that has previously been called diffuse small-cleaved cell lymphoma.
		Mantle cell lymphoma is an aggressive non-Hodgkin's lymphoma that historically been resistant to current standard chemotherapeutic approaches.
		Abstract: Mantle Cell Lymphoma, Campo E. et al., Semin Hematol.
	www.lymphomainfo.net /nhl/types/mantle.html (944 words)

	Malignant Lymphoma Diffuse Small Cell of the Lymph Node
		Malignant Lymphoma Diffuse Small Cell of the Lymph Node
		•Grossly, in common with all lymphomas, the affected gland is enlarged and appears firm and homogenous in consistency.
		•Histologically, the node architecture is replaced by uniform small cells which are apparently composed entirely of a nucleus with little cytoplasm.
	pathweb.uchc.edu /eAtlas/HEM/1873.HTM (297 words)

	Mantle cell lymphoma
		It is assumed that the malignant cells correspond to newly made normal lymphocytes that travel from the bone marrow and reside in primary lymphoid follicles, and in the mantle zones of secondary follicles in the lymph nodes and spleen.
		Mitotic rate is low in the small variant, but increases in the mixed and blastic variants, and recurrences are often accompanied by gradual increase of cell size and cell proliferative fraction (speed of proliferation).
		Mantle cell lymphoma is usually widespread at diagnosis into the lymph nodes, spleen, bone marrow (up to 90%), peripheral blood, and extranodal sites, particularly the Waldeyer’s ring (the ring of adenoid, palatine and lingual tonsils at the back of the mouth) or the gastrointestinal tract.
	www.geocities.com /~vera_b/mcl/mcl.html (3317 words)

	Diffuse small cleaved-cell lymphoma: a heterogeneous disease with distinct immunobiologic subsets.
		Diffuse small cleaved-cell lymphoma: a heterogeneous disease with distinct immunobiologic subsets.
		PURPOSE AND METHODS: Diffuse small cleaved-cell lymphoma (DSCL) is a relatively uncommon non-hodgkin's lymphoma (NHL) in the United States and has not been the subject of recent in-depth study of factors predictive of outcome.
		Neither a history of low-grade lymphoma nor the presence of residual immunologically detectable follicles influenced outcome (P =.93 and.97, respectively).
	www.medscape.com /medline/abstract/1634915 (272 words)

	eMedicine - Lymphoma, Mantle Cell : Article Excerpt by: M Rashid Abbasi, MD
		Background: Mantle cell lymphoma (MCL) is recognized in the Revised European-American Lymphoma and World Health Organization classifications as a distinct clinicopathologic entity.
		MCL was not recognized by previous lymphoma classification schemes; it was frequently categorized as diffuse small-cleaved cell lymphoma (by the International Working Formulation) or centrocytic lymphoma (by the Kiel classification).
		Pathophysiology: MCL is a lymphoproliferative disorder derived from a subset of naive pregerminal center cells localized in primary follicles or in the mantle region of secondary follicles.
	www.emedicine.com /med/byname/lymphoma-mantle-cell.htm (468 words)

	eMedicine - Lymphoma, Mantle Cell : Article by M Rashid Abbasi, MD
		In bone marrow sections, neoplastic cells may infiltrate in a focal, often paratrabecular or diffuse pattern.
		In this small series, the response rate was 81% (complete response rate of 31%) and the median progression-free survival was 20.4 months (95% confidence interval, 17.3-23.6).
		Rosenwald A, Wright G, Wiestner A, et al: The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma.
	www.emedicine.com /med/topic1361.htm (4395 words)

	Sloan-Kettering - Pediatric Lymphomas: Non-Hodgkin's Lymphoma
		The form of non-Hodgkin's lymphoma that develops in children differs from the form that develops in adults based on a difference in the grade of tumor.
		Low-grade (slow growing) types of lymphoma include: small lymphocytic lymphoma; follicular lymphoma; mucosal-associated lymphoma tissue; marginal zone lymphoma; monocytoid B-cell lymphoma (which accounts for 30 to 40 percent of all lymphomas found); and cutaneous T-cell lymphoma.
		The diagnosis of a lymphoma is made by excisional biopsy, a surgical procedure in which a portion of the enlarged lymph node or other suspected areas (known as a "mass") is removed, so that the cells in the mass can be examined.
	www.mskcc.org /mskcc/html/12452.cfm (381 words)

	Human, Mouse, Rat Tissue Microarray (TMA) Slides \| Normal, Tumor, and Diseased \| Frozen and Formalin-fixed for ...
		Diffuse B small non-cleaved cell lymphoma with necrosis
		Diffuse B-large cleaved cell lymphoma of lower jaw
		A common concern in the use of TMAs is related to the ability of a small tissue core to accurately reflect data about large tumor specimens.
	www.imgenex.com /single_tissue_slide.php (1625 words)

	Medical Dictionary: Small cleaved-cell, diffuse lymphoma - WrongDiagnosis.com - WrongDiagnosis.com
		Small cleaved-cell, diffuse lymphoma is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Small cleaved-cell, diffuse lymphoma, or a subtype of Small cleaved-cell, diffuse lymphoma, affects less than 200,000 people in the US population.
		Terms that may be interchangeable with Small cleaved-cell, diffuse lymphoma:
	www.wrongdiagnosis.com /medical/small_cleaved_cell_diffuse_lymphoma_printer.htm (220 words)

	The t(14;18) Is Associated with Germinal Center-derived Diffuse Large B-Cell Lymphoma and Is a Strong Predictor of ...
		The t(14;18) Is Associated with Germinal Center-derived Diffuse Large B-Cell Lymphoma and Is a Strong Predictor of Outcome -- Barrans et al.
		Romaguera J. E., Pugh W., Luthra R., Goodacre A., Cabanillas F. The clinical relevance of t(14;18)/BCL-2 rearrangement and DEL 6q in diffuse large cell lymphoma and immunoblastic lymphoma.
		Stein K., Hummel M., Korbjuhn P., Foss H. D., Anagnostopoulos I., Marafioti T., Stein H. Monocytoid B cells are distinct from splenic marginal zone cells and commonly derive from unmutated naïve B cells and less frequently from postgerminal center B cells with polyclonal transformation.
	clincancerres.aacrjournals.org /cgi/content/full/9/6/2133 (4354 words)

	Clinical Relevance of BCL2, BCL6, and MYC Rearrangements in Diffuse Large B-Cell Lymphoma -- Kramer et al. 92 (9): 3152 ...
		Diffuse large B-cell lymphoma (DLCL) is characterized by a marked degree of morphologic and clinical heterogeneity.
		In 93 patients, lymphoma presented with lymphadenopathy, and these were classified as primary nodal.
		small cells; and in five, it could not be determined.
	www.bloodjournal.org /cgi/content/full/92/9/3152 (6435 words)

	Malignant Lymphoma Diffuse SCC type of the Lymph Node
		•In contrast to the small round cell lymphoma, this particular nuclear morphology shows a deep indentation that appears to make the nucleus curve around itself.
		•Follicular small cleaved cell lymphoma is one of the most common non-Hodgkins lymphomas in the United States, representing approximately 40-50% of all diagnosed cases.
		•Histologically, there is a tendency for the entire node to be replaced by follicles composed primarily of small cells, with scanty cytoplasm and characteristically cleaved appearing nuclei.
	pathweb.uchc.edu /eAtlas/HEM/1877.HTM (233 words)

	New Treatment Regimen May Improve Mantle Cell Lymphoma: Presented at ASH
		MCL is a non-Hodgkin's B-cell lymphoma sometimes called diffuse small-cleaved cell lymphoma, intermediate differentiation lymphoma or centrocytic lymphoma.
		Jurczak said therapeutic response is being monitored at 6 weeks and 3 months followed by 3-month intervals for up to 2 years to assess time to progression.
		In most patients, white blood cell and platelet counts decreased in the first 4 to 5 weeks after being treated with Y-Ibritumomab tiuxetan, with cytopenias lasting an average of 8 to 10 weeks.
	www.docguide.com /dg.nsf/PrintPrint/66221E15058FC2E3852570D70065F40C (637 words)

	The National Cancer Registry, Ireland
		squamous cell carcinoma in situ with questionable stromal invasion
		Paget's disease and infiltrating duct carcinoma of breast
		lymphoma, mixed small cleaved and large cell, follicular
	www.ncri.ie /data.cgi/html/icdo2morphs.shtml (66 words)

	Diffuse small noncleaved-cell, non-Burkitt's lymphoma in adults: a high- grade lymphoma responsive to ProMACE-based ...
		Diffuse small noncleaved-cell, non-Burkitt's lymphoma in adults: a high- grade lymphoma responsive to ProMACE-based combination chemotherapy [published erratum appears in J Clin Oncol 1996 Jun;14(6):1969] -- Longo et al.
		Diffuse small noncleaved-cell, non-Burkitt's lymphoma in adults: a high- grade lymphoma responsive to ProMACE-based combination chemotherapy [published erratum appears in J Clin Oncol 1996 Jun;14(6):1969]
		Burkitt lymphoma in adults: a prospective study of 72 patients treated with an adapted pediatric LMB protocol
	www.jco.org /cgi/content/abstract/12/10/2153 (579 words)

	Burkitt's Lymphoma (malignant lymphoma, small non-cleaved) (Site not responding. Last check: 2007-10-29)
		Note: "Starry sky" pattern is not pathognomonic for Burkitt's lymphoma and may be observed in other highly proliferative lymphomas.
		This term is suggested for those high grade lymphomas in which cell size and nuclear morphology are intermediate between large cell and Burkitt's lymphomas.
		Tumor cells express B cell-associated antigens, are usually negative for CD5 and CD10, and may or may not express SIg.
	wwwpathnet.medsch.ucla.edu /educ/lecture/pathrev/Burkitt.htm (184 words)

	[Peliosis hepatitis during intestinal lymphomatous polyposis treated with chemotherapy and radiotherapy. Regression ...
		We report a case of regressive peliosis hepatis, which occurred in a 55 year-old woman with diffuse intestinal lymphomatous polyposis in remission after treatment with chemotherapy and radiotherapy, and which was cleared after one month treatment with erythromycin.
		The Warthin-Sarry stain, performed to identify a specific agent such as Rochalimaea quintana and henselae, was negative, and the polymerase chain reaction technique could not be performed.
		The observation and the regressive cases recently reported elsewhere, suggest that appropriate antibiotic treatment should be proposed when peliosis hepatis occurs.
	www.aegis.com /aidsline/1996/feb/M9620626.html (412 words)

	AIDS-Related Diffuse Small Cleaved Cell Lymphoma Cancer Related Definition
		AIDS-Related Diffuse Small Cleaved Cell Lymphoma Cancer Related Definition
		Nutrtion Guide Home > NCI Cancer Thesaurus > AIDS-Related Diffuse Small Cleaved Cell Lymphoma
		Synonyms: AIDS-Related Diffuse Small Cleaved Cell Lymphoma, AIDS Associated Diffuse Small Cleaved Cell Lymphoma, AIDS Related Diffuse Small Cleaved Cell Lymphoma, AIDS-Associated Diffuse Small Cleaved Cell Lymphoma
	www.thenutritionguide.com /nci/7803.html (116 words)

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