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Topic: MLL


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  Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene -- Dobson et al. 19 (5): ...   (Site not responding. Last check: 2007-11-07)
Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene
Fusion of lacZ with Mll exon 8 by homologous recombination
(1997) MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).
embojournal.npgjournals.com /cgi/content/full/19/5/843   (5806 words)

  
 MLL Telecom   (Site not responding. Last check: 2007-11-07)
MLL Telecom is strongly committed to protecting the privacy of consumers of its interactive products and services.
The purpose of this MLL Telecom privacy policy is to inform you what kinds of information we may gather about you when you visit MLL Telecom, how we may use that information, whether we disclose it to anyone, and the choices you have regarding our use of, and your ability to correct, the information.
MLL Telecom may have to provide such information in response to legal process, such as a court order or subpoena, or in special cases such as a physical threat to you or others.
www.mlltelecom.com /privacy.htm   (635 words)

  
 Mechanisms of MLL gene rearrangement: site-specific DNA cleavage within the breakpoint cluster region is independent of ...
SAR assays of the germline and episomal MLL bcr.
a 4 kb HindIII fragment from the murine MLL bcr was transfected
(A) Hybridization of undigested genomic DNA from Jurkat (lane 1) and a clone harboring the murine MLL bcr episome (clone muC-6, lane 2) to the 0.2 HB MLL cDNA probe.
hmg.oxfordjournals.org /cgi/content/full/10/22/2481   (7118 words)

  
 Leukemia in Infants -- Felix and Lange 4 (3): 225 -- The Oncologist
Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia.
The t(11;16)(q23;p13) translocation in myelodysplastic syndrome fuses the MLL gene to the CBP gene.
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23).
theoncologist.alphamedpress.org /cgi/content/full/4/3/225   (7171 words)

  
 Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis -- Daser and Rabbitts 18 (9): 965 -- ...
Approximately 5%-10% of all MLL translocations are therapy-related leukemias.
The MLL protein is a multidomain molecule with regions of homology to diverse proteins.
Dobson, C.L., Warren, A.J., Pannell, R., Forster, A., and Rabbitts, T.H. Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.
www.genesdev.org /cgi/content/full/18/9/965   (5994 words)

  
 MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the ...
MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein -- Xia et al.
Corepressors and coactivators may both bind to wild-type MLL; the equilibrium of binding may be influenced by other factors that ultimately determine the function of MLL at a particular target gene locus.
For leukemogenic MLL fusion proteins, the equilibrium of binding may be altered, resulting in the aberrant regulation of MLL target genes.
www.pnas.org /cgi/content/full/100/14/8342   (4572 words)

  
 Mercantile Leasing Limited   (Site not responding. Last check: 2007-11-07)
MLL has emerged as a major player in the leasing industry offering products ranging from Finance Leases to Variable Rate Leases.
MLL's growth over the years can largely be attributed to the dedicated customer care and a superior IT system.
MLL is a Quoted Public Company with limited liability incorporated on 20th January 1982.
www.mll.lk   (134 words)

  
 Welcome to Metropolitan Living Ltd (MLL)   (Site not responding. Last check: 2007-11-07)
MLL has been created to enable MHP to undertake genuine mixed tenure development and to generate profit.
MLL has responsibility for building homes for outright sale on projects where the Trust is building homes for rent and shared ownership.
MLL's first three projects are all in the Midlands where we have been very successful in securing large sites, but where the scope for social renting is more limited than in London.
www.mhp-online.co.uk /mll_html   (282 words)

  
 MLL Telecom
MLL Telecom is experienced in providing solutions throughout the public sector, particularly in rural and remote areas.
MLL Telecom has provided managed wireless bandwidth services to the telecommunications industry for over ten years.
MLL Telecom provide a comprehensive range of broadband managed wireless access solutions for data and voice service providers.
www.mlltelecom.co.uk   (180 words)

  
 t(11;14)(q23;q24) Generates an MLL-Human Gephyrin Fusion Gene along with a de facto Truncated MLL in Acute Monoblastic ...
Southern blot of DNA was digested with BamHI and probed with the 0.9-kb fragment of the MLL gene.
The MLL gene was truncated in intron 9, and the 3' sequence was replaced by the chromosome 14 genome sequence, AL049835.3.
MLL and the COOH terminus of the human gephyrin homologue.
cancerres.aacrjournals.org /cgi/content/full/61/6/2665   (4573 words)

  
 Apoptotic Stimuli Initiate MLL-AF9 Translocations that Are Transcribed in Cells Capable of Division -- Betti et al. 63 ...
In each case, the location of MLL containing DNA was determined using a Southern blot with a probe to the MLL BCR.
MLL cleavage on exposure to a range of apoptotic agents (10).
Thus MLL cleavage is not restricted to malignant cells.
cancerres.aacrjournals.org /cgi/content/full/63/6/1377   (4696 words)

  
 Childhood Acute Lymphoblastic Leukemia With the MLL-ENL Fusion and t(11;19)(q23;p13.3) Translocation -- Rubnitz et al. ...
MLL gene and the presence of the MLL-ENL fusion transcript.
Behm FG, Raimondi SC, Frestedt JL, et al: Rearrangement of the MLL gene confers a poor prognosis in childhood acute lymphoblastic leukemia, regardless of presenting age.
Thirman MJ, Levitan DA, Kobayashi H, et al: Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23; p13.1) in acute myeloid leukemia.
www.jco.org /cgi/content/full/17/1/191   (3031 words)

  
 MLL-ENL Causes a Reversible and myc-dependent Block of Myelomonocytic Cell Differentiation -- Schreiner et al. 61 (17): ...
For comparison, the hybridization pattern of the endogenous MLL gene was determined in mouse 32D cells.
Genomic DNA of md11cells (Lanes 1 and 3) or of 32D cells (Lanes 2 and 4) was digested with either BamHI (left panel) or KpnI (right panel), blotted, and hybridized with a probe corresponding to the 5' end of the MLL-ENL cDNA.
MLL fusion proteins, the cooperation apparently augments the
cancerres.aacrjournals.org /cgi/content/full/61/17/6480   (4786 words)

  
 Leukemia Proto-Oncoprotein MLL Forms a SET1-Like Histone Methyltransferase Complex with Menin To Regulate Hox Gene ...
MLL dimerization and oligomerization (26, 40, 52, 54, 68).
to the incidence and/or phenotypes of MLL leukemias (7, 34,
MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein.
mcb.asm.org /cgi/content/full/24/13/5639   (6933 words)

  
 The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation -- Birke ...
Ernst,P., Wang,J., Huang,M., Goodman,R.H. and Korsmeyer,S.J. (2001) Mll and creb bind cooperatively to the nuclear coactivator creb-binding protein.
Dobson,C.L., Warren,A.J., Pannell,R., Forster,A. and Rabbitts,T.H. (2000) Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.
Yamamoto,K., Hamaguchi,H., Nagata,K., Kobayashi,M. and Taniwaki,M. (1997) Tandem duplication of the MLL gene in myelodysplastic syndrome-derived overt leukemia with trisomy 11.
nar.oxfordjournals.org /cgi/content/full/30/4/958   (5167 words)

  
 The Lacrosse Equipment Superstore
The MLL will expand to four new cities in 2006: Chicago, Denver, Los Angeles and San Francisco.
Hiller resigned the position and is moving on to coach the MLL expansion franchise located in Chicago.
Hiller was named MLL Warrior Coach of the Year in 2005 and 2002.
www.lax.com   (2165 words)

  
 Baltimore Bayhawks   (Site not responding. Last check: 2007-11-07)
In their win was a reflection of what made the Bayhawks so dominant this season- rock solid, aggressive defense that stifles opponents into submission, and an offense as talented and unselfish as any ever assembled on a lacrosse field.
Baltimore’s victory was also due in no small part to Post-Season MVP player-coach Gary Gait’s 6 goal performance that sapped the spirit from an athletic Long Island defense and their stalwart goalkeeper, Greg Cattrano.
At the last whistle, it was the Bayhawks, 15-9 over the Lizards, hoisting the Steinfeld Trophy in front of 6,829 MLL fans.
www.baltimorebayhawks.com   (354 words)

  
 Cooperativity in Transcription Factor Binding to the Coactivator CREB-binding Protein (CBP). THE MIXED LINEAGE LEUKEMIA ...
Binding of MLL to KIX Measured by ITC-- To determine the thermodynamic parameters of MLL binding to the KIX domain of CBP, a 19-mer peptide that encompasses residues
Shown is the MLL19 peptide sequence encompassing the core region of the minimal activation domain from human (h) MLL (24), in alignment with analogous regions from mouse (m) and the pufferfish Takifugu rubripes (p) MLL and the human paralogue MLL2.
Do MLL and c-Myb Act Synergistically in Vivo?-- Both MLL and c-Myb are essential for normal blood cell development and appear to have similar roles in this process.
www.jbc.org /cgi/content/full/277/45/43168   (5781 words)

  
 Long Island Lizards
The award was given to Polanco by MLL Founder Jake Steinfeld and Dave Morrow, at the MLL Awards Banquet last Saturday.
Polanco was also named to the All-MLL Team, along with Lizards midfielder Blake Miller, while veteran defenseman Pat McCabe was named the New Balance Sportsman of the Year.
However, the Lizards were unable to defeat the Baltimore Bayhawks (12-2), who won their second title with a 15-9 win over the Lizards in front of 6,829 fans at Nickerson Field on the campus of Boston University on Sunday afternoon.
www.longislandlizards.com   (337 words)

  
 From the Cover: Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia -- Strick ...
From the Cover: Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia -- Strick et al.
The bottom map represents an enlargement of the 8.3-kb BamHI MLL BCR, which is involved in all MLL chromosome translocations.
The absence of MLL cleavage in topo II-resistant
www.pnas.org /cgi/content/full/97/9/4790   (5487 words)

  
 Granulocytic Sarcoma in MLL-Positive Infant Acute Myelogenous Leukemia : Fluorescence in Situ Hybridization Study of ...
MLL rearrangements were found in 9 (22.5%) of the 40 patients
MLL rearrangements are present in 70 to 80% of acute lymphoblastic
Mathew S, Behm F, Dalton J, Raimondi S: Comparison of cytogenetics, Southern blotting, and fluorescence in situ hybridization as methods for detecting MLL gene rearrangements in children with acute leukemia and with 11q23 abnormalities.
ajp.amjpathol.org /cgi/content/full/159/6/2011   (2602 words)

  
 Major League Lacrosse
Under Daye, Cannons players were named MLL Defensive Player of the Week five times.
Major League Lacrosse (MLL), the premier professional outdoor lacrosse league, announced today its Expansion Draft rules, according to MLL Commissioner David Gross.
MLL CHAMPIONS CUP WINNERS — U13 & U15
www.majorleaguelacrosse.com   (276 words)

  
 Multimedia Learning Lab :: Index
The MLL is open to all UA Faculty, Staff, and Students.
All MLL clients must agree to the MLL Policies to use our resources.
Faculty members can reserve the MLL for their classes and request workshops.
mll.arizona.edu   (84 words)

  
 Chris Massey Named MLL Offensive Player of the Week
Chris Massey, a Garden City native, was named MLL Offensive Player of the Week after scoring a career high five goals, including the game-winner, and adding one assist to lead the Lizards to their second straight win, a 19-14 decision over Philadelphia.
While the MLL has a number of "Weekend Warriors," such as stockbrokers, teachers, accountants and even actors, Massey is the only lawyer to ever play in Major League Lacrosse.
He worked at Bressler for the last two summers, and passed both the New York and New Jersey Bar exams during the 2004 MLL season.
www.antonnews.com /gardencitylife/2005/07/01/sports   (292 words)

  
 Concurrency Abstracts   (Site not responding. Last check: 2007-11-07)
In particular we show that the cut-free proofs of MLL theorems are in a natural bijection with the binary logical transformations of the corresponding operations on the category of Chu spaces on a two-letter alphabet.}
We define a notion of proof function analogous to the notion of truth function, determining a transformation between functors, and show that the transformation denoted by a proof net is dinatural if and only if the proof net is sound, namely acyclic and connected.
Proof functions are of independent interest as a 2-valued model of MLL with MIX.
boole.stanford.edu /abstracts.html   (9620 words)

  
 MLL - Management Learning Laboratories
During the past three decades, Management Learning Laboratories (MLL) has provided comprehensive recreation needs assessment to leisure organizations.
These community-wide surveys have provided valuable baseline information about the recreation behavior of the community members, information about the future recreation needs of the community, information on the public opinion about recreation and leisure, and a map of the recreation-related behavior of the members of the community.
We also encourage you to try our collection of Free Research Resources and download our printable Brochures.
www.m-l-l.com   (142 words)

  
 /// MLL Internships Page ///
They may be paid or unpaid, although most internships available to students are unpaid.
Undergraduate and graduate students may earn 3 upper-level credits by registering for MLL 430 or MLL 790 for Winter, Spring, or Summer 1998 and completing 120 hours of approved internship work.
(N.B. MLL 430 may not be applied towards the requirements of the major).
www.umbc.edu /mll/intern.html   (533 words)

  
 SNP linked to Gene (geneID:4297)   (Site not responding. Last check: 2007-11-07)
SNP are linked from gene MLL via the following methods:
Asn [N] Variations in genomic region of MLL
Click here to turn on the view of snp from GenBank.
www.ncbi.nlm.nih.gov /SNP/snp_ref.cgi?locusId=4297   (48 words)

  
 Welcome to LaxPower   (Site not responding. Last check: 2007-11-07)
Lizards Fall to Bayhawks in MLL Championship, 15-9
In the News: Charlies Murphy Dies; Dingman Reinstated
Long Island Upsets Boston in MLL Semifinal, 19-14
www.laxpower.com   (929 words)

  
 Rochester Rattlers
CASEY POWELL NAMED ALL-PRO & OFFENSIVE PLAYER OF THE YEAR
CASEY POWELL WINS MLL OFFENSIVE PLAYER OF THE WEEK
Casey Powell has 15 goals and 19 assists in his last five games -- all Rochester wins.
www.rochesterrattlers.com   (48 words)

  
 Boston Cannons
ALL YOU NEED TO KNOW ABOUT THIS WEEKEND
Through teamwork and selflessness, the 2005 Boston Cannons fought their way to the best record in both MLL and team history.
Putting no one player above another, the Cannons truly embody the word TEAM.
www.bostoncannons.com   (96 words)

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