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Topic: Macrocephaly

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	Pediatric Macrocephaly
		Infants who come to attention because of macrocephaly and are found to have chronic subdural hematoma must be managed as suspected victims of child abuse.
		The imaging investigation of macrocephaly in infancy is problematic.
		Despite the expense and the requirement for monitored sedation, MR imaging is the modality of choice for investigation of macrocephaly.
	www.ohsu.edu /neurosurgery/conditions/macrocepahly.shtml (702 words)

	MedFriendly.com: Macrocephaly
		Macrocephaly is a rare condition in which the head is abnormally large.
		Compare macrocephaly to microcephaly, which is a rare condition in which the head is abnormally small.
		Macrocephaly is diagnosed by examining the size of the head.
	www.medfriendly.com /macrocephaly.html (1564 words)

	Macrocephaly - Definition, Description, Demographics, Causes and symptoms, Diagnosis, Treatment, Prognosis, Prevention
		Macrocephaly is usually diagnosed by the pediatrician during a physical examination.
		Medical care for children with macrocephaly focuses on management of specific symptoms such as developmental delays and mental retardation and treatment of the primary diagnosis responsible for the macrocephaly.
		Macrocephaly is often present at birth or is a result of conditions that are present at birth.
	www.healthofchildren.com /M/Macrocephaly.html (1192 words)

	Macrocephaly - Children's Healthcare of Atlanta
		Characteristic signs of elevated intracranial pressure are MacEwen's (cracked pot sound on thumping the head), prominent frontotemporal scalp veins, bulging anterior fontanel, impaired upward gaze (sunsetting eyes), unilateral or bilateral sixth cranial nerve paresis, papilledema and, later in the course, alteration of the level of consciousness.
		Macrocephaly associated with primary abnormalities of bone such as achondroplasia and rickets are recognized primarily by the characteristic body habitus and/or laboratory abnormalities.
		From a neurosurgical standpoint the key to evaluation of the infant or child with macrocephaly and suspected intracranial or cranial pathology is diagnostic imaging.
	www.choa.org /default.aspx?id=921 (490 words)

	CIGNA - Macrocephaly, Cutis Marmorata Telangiectatica Congenita Syndrome
		Macrocephaly, cutis marmorata telangiectatica congenita syndrome (M-CMTC) is a very rare, complex disorder of the skin and other organ systems that is probably the result of unpredictable, (sporadic, random) mutations.
		Infants born with macrocephaly, cutis marmorata telangiectatica congenita (M-CMTC) are abnormally large at birth (somatic overgrowth or macrosomia) and have an abnormally large head (macrocephaly) and/or brain (megalencephaly).
		Sturge-Weber syndrome is a rare inherited disorder characterized by the presence of a capillary vascular malformation (port wine stain) typically affecting the upper face and area around the eyes occurring in association with vascular malformations of the lining of the brain (leptomeninges) and eye that leads to glaucoma.
	www.cigna.com /healthinfo/nord1166.html (1507 words)

	Bannayan-Zonana Syndrome
		This report presents a sporadic patient with macrocephaly, lipomas, hemangiomas, and lymphangiomas who died of cardiac and respiratory failure due to progressive cervicomediastinal arteriovenous fistulous hemangiomas at the age of 9 years.
		Familial macrocephaly with mesodermal hamartomas is described as a distinct syndrome in nine individuals from four families.
		Macrocephaly with normal ventricular size, mental retardation, central nervous system vascular malformations, intestinal polyposis, skeletal abnormalities, and thyroid tumors were the most common systemic featues.
	www.thedoctorsdoctor.com /diseases/bannayan_zonana_syndrome.htm (2343 words)

	Macrocephaly (Site not responding. Last check: 2007-10-30)
		Macrocephaly in the neonatal period is defined as a head circumference that measures greater than the second standard deviation above the mean for gestational age (Table 283.1).
		Race and sex should be considered before making the diagnosis of macrocephaly.
		Table 283.1— Macrocephaly: upper limits of normal head circumference for gestational age.
	pediatricneuro.com /alfonso/pg283.htm (51 words)

	Melanie D (Site not responding. Last check: 2007-10-30)
		determined that macrocephaly at birth is a significant risk factor for the later development of autism, with an odds ratio of 5.44.
		By studying this homogenous group of children with autism and macrocephaly and their non-autistic macrocephalic parents, we should be able to identify the part of the brain that causes their autism.
		Macrocephaly is due to an increase in ground substance, as opposed to an increase in the number of neurons.
	www.missouri.edu /~mde6cb/melanie_d.htm (2263 words)

	Macrocephaly in NF1
		Macrocephaly, which is relatively common, has been considered a nonspecific finding in NF1.
		For practical purposes, macrocephaly may be defined as a condition where head circumference is above the 97th percentile (> + 2 SD) for age and sex.
		They suggested that macrocephaly in NF1 has a postnatal onset because, in children between two and six years of age, head circumference increased from the 48th to the 77th percentile, at which level it remained in all the older patients.
	herkules.oulu.fi /isbn9514271394/html/x1232.html (1200 words)

	CIGNA - Cutis Marmorata Telangiectatica Congenita
		A few individuals may have other symptoms such as a detached retina of the eye, high blood pressure (hypertension), abnormal placement of the urinary opening (meatus) on the underside of the penis (hypospadias), and/or growth deficiencies.
		Sturge-Weber syndrome is a rare inherited disorder characterized by the presence of a port wine colored birthmark (angioma) on the facial area and intracranial abnormalities that are present at birth (congenital).
		Macrocephaly with cutis haemangioma and syndactyly-a distinctive overgrowth syndrome.
	www.cigna.com /healthinfo/nord1000.html (1910 words)

	Indian Pediatrics - Editorial
		It is characterized by macrocephaly and early onset white matter degeneration.
		Macrocephaly is present at birth or develops during the first year of life.
		Macrocephaly is present at birth or, more commonly, develops within the first year of life in all patients.
	www.indianpediatrics.net /jan2005/jan-60-63.htm (1226 words)

	Macrocephaly
		Smith’s book of recognizable patterns of human malformations lists macrocephaly as a frequent finding in 27 syndromes and as an occasional finding in 16 more.
		Macrocephaly during the neonatal period results from enlargement of any component or “space” of the head.
		Scout film for CT of the brain demonstrates subgaleal hemorrhage extending to the neck.
	pediatricneuro.com /alfonso/pg284.htm (323 words)

	Welcome to Macrocephaly-cmtc site (Site not responding. Last check: 2007-10-30)
		This is described as having cherry red macules, megalencephaly with hemifacial and segmental overgrowth, macrosomia, and cutis marmorata telangiectasia congenital of the trunk,and visceral and subcutaneous cavernous hemangiomas.
		The Macrocephaly is accompanied by MRI findings of CNS dysgenesis with protrusion of the cerebellar tonsils through the foremen magnam lumbar syrinx, and hydrops of the optic nerves.
		Cutis marmorata telegiectatica congenital (CMTC) is a condition characterized by cutis marmorata, which is congenital generalized or segmental "marbled" or "mottled" skin appearance caused by prominent capillaries and veins, and vascular lesions characterised as telangiectasias, which resemble spider angiomas, and venous dilatation or phlebectasias.
	www.macrocephaly-cmtc.com (174 words)

	bz-update.html
		AB: Bannayan-Riley-Ruvalcaba syndrome (BRRS) is an autosomal dominant condition of macrocephaly in combination with lipomas/hemangiomas, hypotonia, developmental delay, and a lipid myopathy.
		AB: Bannayan-Zonana syndrome is a rare disorder characterized by macrocephaly and multiple soft tissue and visceral hamartomas.
		AB: The muscle biopsy results from 14 children with macrocephaly and hypotonia/weakness were correlated with clinical findings compatible with any of the autosomal dominant macrocephaly syndromes.
	www.indiana.edu /~pietsch/bz-update.html (1527 words)

	WFTV.com - Health Centers - Increased Head Circumference
		Symptoms associated with this condition?include vomiting, eyes deviating downward, and irritability.
		Benign familial macrocephaly (family tendency toward large head size)
		Macrocephaly is usually discovered by the health care provider during a routine well-baby exam.
	www.wftv.com /encyclopedia/6864272/detail.html (561 words)

	Bannayan's syndrome (www.whonamedit.com)
		Harris and William R. Smith, Oklahoma, in 1960 described a mother and four of her seven children with the trias of macrocephaly, pseudopapilledema, and multiple haemangiomas.
		Bannayan in 1971 described a single case with macrocephaly and multiple lipomas and haemangiomas.
		Ruvalcaba, S. Myhre, and David W. Smith, paediatricians, Seattle, in 1980 described two patients with macrocephaly, intestinal polyposis and spotted pigmentation of the shaft of penis.
	www.whonamedit.com /synd.cfm/1276.html (243 words)

	Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour ...
		Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations -- Butler et al.
		Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
		Macrocephaly is also seen in 20% of patients with autism.
	jmg.bmjjournals.com /cgi/content/full/42/4/318 (2816 words)

	Temporal Lobe, Autism, and Macrocephaly -- Bigler et al. 24 (10): 2066 -- American Journal of Neuroradiology
		Growth plots by age for total temporal lobe white matter and gray matter, fusiform gyrus white and gray matter, and parahippocampal gyrus white and gray matter.
		The nature of the relationship of structure, development, and age was tested by either a linear or quadratic fit.
		In autism with macrocephaly, temporal lobe structures are proportional
	www.ajnr.org /cgi/content/full/24/10/2066 (5292 words)

	Arch Neurol -- Abstract: Macrocephaly with head growth parallel to normal growth pattern: neurological, developmental, ...
		Arch Neurol -- Abstract: Macrocephaly with head growth parallel to normal growth pattern: neurological, developmental, and computerized tomography findings in full-term infants, August 1980, Pettit et al.
		Macrocephaly with head growth parallel to normal growth pattern: neurological, developmental, and computerized tomography findings in full-term infants
		Fifteen infants with macrocephaly had a head growth pattern parallel to 2
	archneur.ama-assn.org /cgi/content/abstract/37/8/518 (199 words)

	Health Topics
		Symptoms associated with this condition include vomiting, eyes deviating downward, and irritability.
		Macrocephaly is usually discovered by the health care provider during a routine well-baby exam.
		The medical history will be obtained and a physical examination performed.
	www.netwellness.org /ency/article/003305.htm (511 words)

	[No title]
		The March 1988 notice of the rating decision informed the appellant that he was granted service connection for "traumatic brain disease." In July 1990, the appellant submitted a claim for increased compensation for the residuals of being struck by lightning.
		He specifically noted five diagnoses: (1) Post-traumatic cephalgia; (2) macrocephaly; (3) low back syndrome with spondylolysis and stable grade I spondylolisthesis; (4) non-obstructive communicating hydrocephalus, age indeterminate with no change over six months; and (5) possible isodense bilateral frontal subdural hematomas.
		Determine whether claims for service- connection for any of the following are duplicative of claims already granted or previously denied: (1) Post-traumatic cephalalgia; (2) macrocephaly; (3) low back syndrome with spondylolysis and grade I spondylolisthesis; (4) non-obstructive communicating hydrocephalus; and (5) possible isodense bilateral frontal subdural hematomas.
	www.va.gov /vetapp/files1/9401192.txt (1541 words)

	Macrocephaly, multiple lipomas, and hemangiomas definition - Medical Dictionary definitions of popular medical terms
		Macrocephaly, multiple lipomas, and hemangiomas definition - Medical Dictionary definitions of popular medical terms
		Macrocephaly, multiple lipomas, and hemangiomas: Bannayan syndrome, a genetic disease characterized by macrocephaly (enlarged head), multiple lipomas (benign fatty tumors) and hemangiomas (benign blood vessel tumors).
		The macrocephaly occurs without enlargement of the cerebral ventricles.
	www.medterms.com /script/main/art.asp?articlekey=20165 (280 words)

	Medical Symptom: Macrocephaly - CureResearch.com (Site not responding. Last check: 2007-10-30)
		Macrocephaly: Macrocephaly is listed as an alternate name or description for symptom Swollen head.
		For a medical symptom description of 'Macrocephaly', the following symptom information may be relevant to the symptoms: Swollen head (symptom).
		However, note that other causes of the symptom 'Macrocephaly' may be possible.
	www.cureresearch.com /symptom/macrocephaly_printer.htm (122 words)

	Health and Medical Information produced by doctors - MedicineNet.com
		After a second CT scan at 14 months and only slight head growth, the neurosugen felt that a shunt was not needed, said that he'd grow out of it, declared him Macrocephaly and turned him back over to his pediatrion.
		(4) Macrocephaly: The neurosurgeon says he has macrocephaly, that is just a big head due to a big brain.
		Although this might conceivably be due to the brain just normally being big, we are concerned about the macrocephaly.
	www.medicinenet.com /script/main/ques.asp?qakey=13241 (621 words)

	Prospective Evaluation of the Brain in Asymptomatic Children with Neurofibromatosis Type 1: Relationship of ...
		Prospective Evaluation of the Brain in Asymptomatic Children with Neurofibromatosis Type 1: Relationship of Macrocephaly to T1 Relaxation Changes and Structural Brain Abnormalities -- Steen et al.
		Prospective Evaluation of the Brain in Asymptomatic Children with Neurofibromatosis Type 1: Relationship of Macrocephaly to T1 Relaxation Changes and Structural Brain Abnormalities
		display macrocephaly in the absence of hydrocephalus, we sought
	www.ajnr.org /cgi/content/abstract/22/5/810 (396 words)

	Macrocephaly - New Treatments, May 2, 2006
		Here we have again a big differential of macrocephaly, large head, macrocefaly.
		You will notice that when I talked about macrocephaly I didn’t really say anything about hydrocephalus, because that will come under CSF circulation and that’s not really big encephalus
		Obstructive hydrocephalus can be due to a congenital problem, like aqueductal stenosis.
	www.ccspublishing.com /journals5a/macrocephaly.htm (708 words)

	Macrocephaly traced in Burnt City, Iran (Site not responding. Last check: 2007-10-30)
		From the Persian Journal: Macrocephaly Traced in Burnt City, Iran.
		The latest excavations in the archaeological site of Burnt City, in Sistan-Baluchistan has led to the discovery of a five-thousand-year old female skeleton which shows traces of macrocephaly.
		According to head of the anthropology team in the Burnt City, Farzad Forouzanfar, the discovered skull has a very thick shell, which shows that the woman has died of macrocephaly.
	www.mirabilis.ca /archives/002866.html (110 words)

	Definition of macrocephaly - Merriam-Webster Online Dictionary
		Click here to search for another word in the Merriam-Webster Online Dictionary.
		Learn more about "macrocephaly " and related topics at Britannica.com
		See a map of "macrocephaly " in the Visual Thesaurus
	www.m-w.com /dictionary/macrocephaly (41 words)

	Porencephaly Information Page: National Institute of Neurological Disorders and Stroke (NINDS)
		Diagnosis is usually made before an infant reaches his or her first birthday.
		Symptoms of porencephaly include delayed growth and development, spastic hemiplegia (slight or incomplete paralysis), hypotonia (low muscle tone), seizures (often infantile spasms), and macrocephaly (large head) or microcephaly (small head).
		Children with porencephaly may have poor or absent speech development, epilepsy, hydrocephalus (accumulation of fluid in the brain), spastic contractures (shrinkage or shortening of the muscles), and mental retardation.
	www.ninds.nih.gov /disorders/porencephaly/porencephaly.htm (441 words)

	Hannah June Tangen's Homepage - Macrocephaly, Asthma, Gerd, Reflux, large head, Dysphagia (Site not responding. Last check: 2007-10-30)
		HI my name is Hannah June and I was born on November 9, 1999 and as I am sure you heard, I came a little early!!
		I was diagnosed with Macrocephaly, Dysphagia, Reflux and Asthma but the only issue that still bothers me is my Asthma.
		I now do nebulizer treatments as needed and I take Zyrtec and Singulair for allergies which seems to really help!
	www.jefftangen.com /hannah/index.html (134 words)

	Infants Health Forum - Hydrocephalus, Macrocephaly, Subdural Hematoma... (Site not responding. Last check: 2007-10-30)
		Infants Health Forum - Hydrocephalus, Macrocephaly, Subdural Hematoma...
		Medical Questions-> Health Forums -> Infants Health -> Hydrocephalus, Macrocephaly, Subdural Hematoma...
		I am a young mother (19) of one, a little boy who will be a year old on 1/30/04.
	ehealthforum.com /health/topic7145.html (942 words)

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