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Topic: Macromolecule

In the News (Fri 25 Apr 14)

Literally speaking, a macromolecule is a large molecule, and may be a protein, a lipid, a nucleic acid, or a polysaccharide (i.e., a starch).
Carbon nanotubes are macromolecules, as are the larger sheets of graphite.
A macromolecule may achieve its size through being a single polymeric chain, or it may be composed of multiple smaller units that are noncovalently bound.
www.ebroadcast.com.au /lookup/encyclopedia/ma/Macromolecule.html   (209 words)

 Macromolecule - Wikipedia, the free encyclopedia
A macromolecule is a large molecule with a large molecular mass, but generally the use of the term is restricted to polymers and molecules which structurally include polymers.
The term macromolecule is also sometimes used to refer to aggregates of two or more macromolecules held together by intermolecular forces rather than by chemical "bonds".
According to IUPAC recommendations the term macromolecule is reserved for an individual molecule, and the term polymer is used as to denote a substance composed of macromolecules.
en.wikipedia.org /wiki/Macromolecule   (404 words)

 Wel-Come to Cosmo Films.com
This statement fails in the case of certain macromolecules for which the properties may be critically dependent on fine details of the molecular structure.
The largest constitutional unit contributed by a single monomer molecule to the structure of a macromolecule or oligomer molecule may be described as either monomeric, or by monomer used adjectivally.
In an isotactic macromolecule, the configurational repeating unit (see Definition 1.16) is identical with the configurational base unit.
cosmofilms.com /bopp/PolyDictionaryContent.html   (4181 words)

 Highbeam Encyclopedia - Search Results for macromolecule
macromolecule MACROMOLECULE [macromolecule] term that may refer either to a crystal such as a diamond, in which the atoms are identical and held by covalent bonds (see chemical bond) of equal strength, or to one of the units that compose a polymer.
Macromolecules such as proteins and nucleic acids are vital to
Macromolecule Production & Economics Conference to Be Held February 27-28, San Diego, CA.
www.encyclopedia.com /SearchResults.aspx?Q=macromolecule   (307 words)

 A Comparison of the Macromolecule Content in Boiled Brassica oleracea versus Steamed Brassica oleracea
Macromolecule analysis was completed using Benedict’s, Barfoed’s, Selivanoff’s, Bial’s and Iodine test for carbohydrates, paper chromatography for photosynthetic pigment identification and the Bradford Assay for total protein concentration.
The water from the boiling process was also analyzed to either support or refute the hypothesis that macromolecule content of boiled broccoli would be lower then the content in steamed broccoli due to macromolecule loss to the water used in the boiling process (Bale, Amanda et al.).
What we can show is evidence of lost macromolecules as a result of the boiling process, as shown by the positive results in both the carbohydrate tests and the Bradford assay of the water from the boiling process.
www.msu.edu /course/lbs/145/luckie/inquiriesF2004/broccoli.html   (1108 words)

Mobility is an intrinsic property of the macromolecule, depending only on its charge and frictional properties.
For a real macromolecule in solution, both the actual net charge q and the frictional factor f will be difficult to ascertain.
Figure 16.20  A region of a macromolecule with its surrounding cloud of counterions.
www.union.edu /PUBLIC/PHYDEPT/newmanj/2000/electrophoresis.htm   (1657 words)

 Interdependence in Macromolecule Synthesis: Evidence for Design
Macromolecules in the cell such as DNA, RNA, and proteins are interdependent for mutual synthesis.
Macromolecule synthesis in the cell is a very efficient process, far exceeding the efficiency of laboratory synthesis.
From an organic soup of small molecules and macromolecules to a primitive living organism is a giant step.
www.creationresearch.org /crsq/articles/14/14_1/enzymes/enzymes.html   (4244 words)

 Macromolecule   (Site not responding. Last check: 2007-10-13)
A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
http://www.iupac.org/reports/1996/6812jenkins/molecules.html1.1 A macromolecule is a molecule composed of a very large number of atoms.
The integral domains of crystals and metals, while composed of very large numbers of atoms joined by molecule-like bonds, are rarely referred to as "macromolecules." The term "macromolecule" is sometimes used to refer to aggregates of two or more macromolecules held together by intermolecular forces rather than by chemical bonds.
macromolecule.iqnaut.net   (389 words)

 Detection of analytes in aqueous environments - Patent 6794195
The indicator macromolecule of claim 1, wherein the indicator component monomer is selected from the group consisting of a lanthanide chelate and a polyaromatic hydrocarbon.
The indicator macromolecule of claim 1, wherein the analyte detected is selected from the group consisting of a vicinal diol; an.alpha.-hydroxy acid, a.beta.-keto acid oxygen; carbon dioxide; zinc, potassium, hydrogen, or carbonate ions; a toxin; a mineral; and a hormone.
The macromolecule of claim 44, wherein the macromolecule is capable of detecting the presence or concentration of an analyte.
www.freepatentsonline.com /6794195.html   (10618 words)

 Cylindrical macromolecule and photometer and magnetometer using the same - Patent 5933791   (Site not responding. Last check: 2007-10-13)
In the macromolecule, the hexagonal structure is repeated both horizontally and vertically, i.e., in both axial and circumferential directions of the macromolecule, to form a cylindrical structure.
In the photometer, a macromolecule having a feature of an insulating material is adopted such that an intensity of infrared light is measured according to a photoconductive effect thereof.
In accordance with the present invention, the elastic constant of the cylindrical macromolecule in the direction vertical to the axis of the carbon tube is as small as those of copper and aluminum.
www.freepatentsonline.com /5933791.html   (5891 words)

 Photochemical Internalization - A novel technology for improving macromolecule-based treatment   (Site not responding. Last check: 2007-10-13)
Macromolecules are widely acknowledged to have a large potential as therapeutic agents, and numerous clinical trials both with gene, protein and oligonucleotide therapy are underway.
Since most macromolecules are unable to pass directly through the cell membrane, inefficient delivery of macromolecules to the cell interior has constituted a severe obstacle for realising the therapeutic potential of large classes of macromolecules.
Although most macromolecules can be taken into the cell efficiently by the process of endocytosis, molecules taken up in this way will as a rule be trapped inside endocytic vesicles, finally being degraded in lysosomes before they have been able to exert a biological effect.
www.pcibiotech.com /technology   (227 words)

 INHALE THERAPEUTIC SYSTEMS INC (Form: 10-K, Received: 03/29/1999 17:09:20)
Approximately 30 macromolecule drugs are approved for marketing in the United States and approximately 120 additional macromolecule drugs are in human clinical trials, many for chronic and subchronic diseases.
In addition, Inhale believes that some macromolecules may be inactivated by nebulization and that many dry powder systems do not provide the protection needed for long-term stability that may be needed for macromolecule formulations.
Through its work with numerous macromolecules, Inhale is developing an extensive body of knowledge on aerosol dry powder formulations, including knowledge relating to powder flow characteristics and solubility within the lung, as well as physical and chemical properties of various excipients.
www.shareholder.com /common/edgar/906709/1047469-99-12122/99-00.html   (16898 words)

 macromolecule — Infoplease.com
Glossary of Chemical Terms - M - macromolecule · manometer · matter · meniscus · metabolite · metal ·; metalloid · meteorite · meter · methanogenic · methylated · micromolar · microscopic · mitochondrion · mixture · molality · molarity · mole · molecule ·; monomer · monooxygenase · monosaccharide
Transdermal macromolecule drug delivery: human trials show this non-invasive, alternative drug delivery method may provide a pain-free,......
A rheological and morphological model for blends of flexible and rigid macromolecules.
www.infoplease.com /ce6/sci/A0831044.html   (257 words)

 International Union of Pure and Applied Chemistry
A macromolecule (see Definition 1.1), the structure of which essentially comprises the repetition of more than one type of constitutional unit (see Definition 1.14), or a macromolecule the structure of which comprises constitutional units not all connected identically with respect to directional sense.
A macromolecule (see Definition 1.1) that comprises constitutional units (see Definition 1.14) connected in such a way that adjacent constitutional units are joined to each other through three or four atoms, two on one side and either one or two on the other side of each constitutional unit.
A macromolecule (see Definition 1.1) that comprises constitutional units (see Definition 1.14) connected in such a way that adjacent constitutional units are joined to each other through more than four atoms, more than two on at least one side of each constitutional unit.
www.iupac.org /reports/1996/6812jenkins/molecules.html   (2949 words)

 [No title]
Degradation of polysaccharides amyA cytoplasmic alpha-amylase 10 2.1.3 Macromolecule metabolism
Degradation of proteins, peptides, glyco" dcp dipeptidyl carboxypeptidase II 10 2.1.4 "Macromolecule metabolism
Polysaccharides - (cytoplasmic)" slyD FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) 10 2.2.09 "Macromolecule metabolism
www.ihes.fr /~materials/genomes/Ecoli/genelist.txt   (15212 words)

 Title page for ETD etd-03252005-122230
There is particular emphasis on incorporation of stimuli responsive materials into multi-layer thin film constructs with the main goal being fabrication of highly functional materials with tunable release characteristics.
Chapter 2 illustrates the progression of controlled macromolecule release from hydrogel and microgel materials and sets up the scope of this thesis work.
These model experiments could prove useful in design of tunable macromolecule drug release from functionally modified microgels and could aid in the tailored design of peptide-loaded microgel thin films.
etd.gatech.edu /theses/available/etd-03252005-122230   (237 words)

 Spectroscopic Assessment of Alterations in Macromolecule and Small-Molecule Metabolites in Human Brain After Stroke -- ...
Lactate signal declined over time, whereas the macromolecule peaks, especially those at 0.9 and 1.3 ppm, were greatest in the subacute period.
Note the spatial correlation of the lesion and regions of greatest lactate and 1.3-ppm macromolecule signal increase and of NA decrease.
Discrimination of metabolite from lipid and macromolecule resonances in cerebral infarction in humans using short echo proton spectroscopy.
stroke.ahajournals.org /cgi/content/full/32/12/2797   (3634 words)

 INHALE THERAPEUTIC SYSTEMS (Form: 10-K, Received: 03/23/1998 15:51:37)
In addition to Pfizer, Baxter and Lilly, the Company is engaged in early stage feasibility and preclinical research and development collaborations with Centeon L.L.C. (a joint venture of Hoechst AG and Rhone-Poulenc Rorer, Inc.) on alpha-1 proteinase inhibitor for genetic emphysema and Genzyme Corporation on gene vectors for lung diseases.
In addition to developing a pulmonary delivery system for macromolecules, Inhale is investigating opportunities of leveraging its technology for small molecules where there is a clear, demonstrable need for an alternative drug delivery system and where the Company's existing technology can be applied without significant modification.
The initial screening determinant for the feasibility of pulmonary delivery of any systemic macromolecule drug is pulmonary bioavailability, which measures the percentage of the drug absorbed into the bloodstream when delivered directly to the lungs.
www.shareholder.com /common/edgar/906709/1047469-98-10980/98-00.html   (16961 words)

 Tumor Accumulation of Macromolecule Drug Carriers   (Site not responding. Last check: 2007-10-13)
As a result, proteins and other macromolecules move more easily into tumors than normal tissue; the lack of a functioning lymphatic system around tumors also slows down clearance.
The authors stress that their results are not universally applicable, because individual properties of a macromolecule and the structure of the tumor tissue affect uptake and retention.
Still, their method could be used to optimize almost any macromolecule, including antibodies, cytokines, and antioangiogenic drugs.
www.acs.org /portal/a/c/s/1/feature_pro.html?id=c373e90a4f596c128f6a17245d830100   (446 words)

 macromolecule struct Reference
macromolecule_get_one_steric)(struct macromolecule *thee, ionlist *ions, int type, int pos, char mode)
Coordinate vector for the center of the macromolecule (Cartesian in
double(* macromolecule::macromolecule_get_one_steric)(struct macromolecule *thee, ionlist *ions, int type, int pos, char mode)
mccammon.ucsd.edu /isim/html/structmacromolecule.html   (391 words)

 ATP reduces macromolecule permeability of endothelial monolayers despite increasing [Ca2+]i -- Noll et al. 276 (6): ...
ATP reduces macromolecule permeability of endothelial monolayers despite increasing [Ca2+]i -- Noll et al.
Dual role of cGMP in modulation of macromolecule permeability of aortic endothelial cells.
Neuropeptide Y reduces macromolecule permeability of coronary endothelial monolayers.
ajpheart.physiology.org /cgi/content/full/276/6/H1892   (4629 words)

 macromolecule class
Class representing a generic macromolecule and an interface.
To be able to handle different macromolecule types function pointers are used (which replace virtual abstract functions and inheritance in Clean OO-C) Function Documentation
Gives maximum cylindrical radius of a PQR-based macromolecule for a cylinder centered at {0.0,0.0,0.0}.
mccammon.ucsd.edu /isim/html/group__macromolecule.html   (1992 words)

 BC Online: 5A - Reversible Binding 1
In fact, binding and subsequent release of a ligand might be the sole function of the macromolecule (example myoglobin binding oxygen).
M is free macromolecule, L is free ligand, and ML is macromolecule-ligand complex
In a typical ITC experiment, a solution of a ligand (a small molecule or a macromolecule) is titrated against a solution of a binding partner (e.g.
employees.csbsju.edu /hjakubowski/classes/ch331/bind/olbindderveq.html   (4894 words)

 macromolecule.h File Reference
Data members and function declarations for class macromolecule.
Gives maximum spherical radius of a PQR-based macromolecule for a sphere centered at {0.0,0.0,0.0}.
Born_shift (macromolecule *thee, double xshift, double yshift, double zshift)
mccammon.ucsd.edu /isim/html/macromolecule_8h.html   (744 words)

FSRI's Macromolecule Permeability Through A Microfluidic Demineralized Bone Tissue experiment will examine the flow of extravascular nutrient fluids through...
Strategic Research Institute is pleased to announce the upcoming Peptides and Therapeutic Proteins: New Opportunities for Macromolecule Development, Delivery...
“We are using DNA to build structural constraints that control the movement and shape of an attached macromolecule, RNA.â€?.
www.mongabay.com /igapo/biotech/macromolecule.html   (163 words)

 Overview of the AutoTools Suite.
Setting the number of grid points in each direction (which has to be an even number) and the spacing between the points.
If no macromolecule has been selected, it is not possible to write a grid parameter file and the user gets a warning message to that effect.
Likewise, the types of the maps to be calculated must be set before the grid parameter file is written and a warning message to this effect appears if the types have not been set.
www.scripps.edu /~sanner/python/adt/autotoolsoverview.html   (1762 words)

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