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| | DARE abstract990495 (Site not responding. Last check: 2007-10-26) |
 | | IIT decreased the number of macrovascular events (OR=0.55, 95% CI: 0.35,0.88, P=0.015) but had no significant effect on the number of patients developing macrovascular disease (OR=0.72, 95% CI: 0.44,1.17, P=0.22) or on macrovascular mortality (OR=0.91, 95% CI: 0.31,2.65, P=0.93). |
 | | The 6 studies were similar in quality; all scored full marks for explicit entry criteria, similarity of baseline characteristics, adequacy of follow-up, and intention-to-treat analyses; the method of randomization was unclear in 3 of the studies. |
 | | IIT decreases the extent of early macrovascular disease in young individuals with type 1 diabetes but has no effect on the number of patients affected or on macrovascular mortality. |
| nhscrd.york.ac.uk /online/dare/990495.htm (862 words) |
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