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Topic: Macules

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In the News (Fri 22 Jun 18)

  Acquired bilateral nevus of Ota-like macules
Acquired bilateral nevus of Ota-like macules were first described in 1984 as blue-brown or slate-gray, small patches that occurred on the lateral sites of the forehead, temples, upper eyelids, malar areas, root of the nose, and ala nasi, without ocular or mucosal pigmentation [1].
The macules are most often seen in women of Asian descent and usually appear in the fourth or fifth decade [2].
Acquired bilateral nevus of Ota-like macules are differentiated from bilateral nevus of Ota by the later age of onset and the lack of conjunctival, mucosal, and tympanic membrane involvement [1].
dermatology.cdlib.org /114/NYU/NYUtexts/0315051.html   (517 words)

 NYU SoM - Dept. of Dermatology
Numerous tan-to-medium-brown macules and patches that measured 2 mm to 6 cm in diameter were present on the face, trunk, and extremities, with an increased density of smaller macules in the axillae and groin.
Although blue-red macules are characterized by their color and pseudoatrophic macules by their anetoderma-like appearance, there is considerable overlap between the two entities.
Blue-red macules have been observed in patients as young as five years of age, and pseudoatrophic macules may be present at birth.
www.med.nyu.edu /dermatology/sem_conf/111505-4.html   (895 words)

 American Vitiligo Research Foundation   (Site not responding. Last check: 2007-10-04)
The typical vitiligo macule is chalk white in color, has convex margins (as if the white areas were flowing into normally pigmented skin), is 5mm to 5cm or more in diameter, and is round, oval, or elongated in shape.
The focal type is characterized by one or more macules on a single site; in some cases, this may be an early evolutionary stage of one of the other forms of the disease.
The segmental type, which is uncommon, is characterized by one of several macules on one hand or one side of the body.
www.avrf.org /PAGES-LEVEL2/vit_questions.html   (862 words)

A macule is a non infiltrated mark which differs in colour from adjacent skin.
Pigmentary macule — varying in size,their colour ranging from ochre to dark brown,corresponding to melanin hyperpigmentation in the epidermis (e.g.freckles).
Achromic macules — are white marks varying in shape and size which results from a decrease in the melanin content of the epidermis (e.g.
www.acneshoot.com /macules.htm   (210 words)

 Idiopathic Eruptive Macular Pigmentation
IEMP is characterized by asymptomatic, pigmented macules involving the neck, trunk, and proximal extremities.
It is characterized by asymptomatic, pigmented macules involving the neck, trunk, and proximal limbs.
Idiopathic eruptive macular pigmentation is a rare condition characterized by asymptomatic pigmented macules involving the neck, trunk, and proximal portions of the extremities.
www.thedoctorsdoctor.com /diseases/iemp.htm   (1045 words)

 Oral Erythematous Macule and Erosion
Three common red, flat lesions in the mouth are (1) the erythematous macule and erosion, (2) the purpuric macule, and (3) the granulomatous stage of the inflammatory hyperplasia.
The usual sites for erythematous macules are on the front and the side of the tongue, the floor of the mouth, the back of the palate, the cheek, and the wet surfaces of the lips.
Your dentist will help you to determine whether the lesion is a (1) traumatic erythematous macule, (2) purpuric macule of oral sex, (3) palatal bruising because of severe coughing or severe vomiting, (4) macular hemangioma, (5) atropic candidiasis, (6) mononucleosis and histoplasmosis, (7) herpangina, (8) erythroplakia, and (9) squamous cell carcinoma.
www.softdental.com /diseases/erythematous_macule_and_erosion.html   (578 words)

 Final Diagnosis -- Case 190
The brown to fl, freckle-like hyperpigmented macules of PJS are commonly found on the buccal mucosa, nose, lips, and skin of the perioral and perianal regions.
Although the presence of mucocutaneous melanocytic macules is considered an important diagnostic criterion for PJS, a number of studies suggest that they are unreliable indicators, being present in only 80-90% of patients (Brigg, et al).
The absence of these macules in post-pubertal patients may mislead clinicians who rely upon a simple visual inspection of the skin to confirm a suspicion of PJS (Erbe).
path.upmc.edu /cases/case190/dx.html   (708 words)

 Ash Leaf Spots - New Treatments, May 2, 2006   (Site not responding. Last check: 2007-10-04)
The lance ovate hypopigmented macule (ash leaf macule) is the characteristic lesion of tuberous sclerosis.
The ash leaf macule may be seen in the general population; therefore it is considered only a tertiary criterion for tuberous sclerosis.
The ash leaf macules are not depigmented but hypopigmented, with functional melanocytes remaining in the affected areas that are normal in number but have smaller melanosomes and melanin content.
www.ccspublishing.com /journals3a/ash_leaf_macules.htm   (489 words)

 NF1 as a clinical entity
The presence and nature of the main diagnostic signs – café-au-lait macules, freckles, neurofibromas and Lisch nodules – in several population or clinical studies from different countries were recently evaluated by Pöyhönen (2000a).
The macules are not seen in newborns, but increase both in number and in size with age.
In the Northern Finnish study (Pöyhönen 2000a), macules were seen in all patients under 30 years of age, but in only 75% of those aged over 60 years.
herkules.oulu.fi /isbn9514271394/html/x302.html   (1530 words)

 Principles of Pediatric Dermatology - Chapter 29 : ERYTHEMAS AND URTICARIA
Skin lesions initially appear as erythematous blotchy macules, papules or pustules mainly on the trunk, face and proximal parts of the limbs.
The clinical picture varies from scanty urticarial lesions and pigmented flat macules with irregular edges that appear after scratching of the skin.
The lesions are in the form of itchy macules around 4mm in diameter, lightly pigmented appearing after rubbing or scratching of the skin surface.
www.drmhijazy.com /english/chapters/chapter29.htm   (3056 words)

 Acne Scarring
Macules or "pseudo-scars" are flat, red or reddish spots that are the final stage of most inflamed acne lesions.
After an inflamed acne lesion flattens, a macule may remain to "mark the spot" for up to 6 months.
Atrophic macules are usually fairly small when they occur on the face, but may be a centimeter or larger on the body.
skincare.drworkmd.com /acneScarring.html   (2015 words)

Initial lesions tend to be vaguely defined hypopigmented or erythematous macules, i.e., indeterminate.
Skin lesions are nonanesthetic and include macules and papules, progressing to nodules; and generalized thickening, especially of the ears, face, extremities, and buttocks.
Skin lesions are anesthetic and include well-demarcated macules and plaques that range from less than one cm to large enough to cover most of a body area.
www3.baylor.edu /~Charles_Kemp/leprosy.htm   (1048 words)

 Diagnosis in Dermatology
Same as macule but exceeding 1 cm in diameter.
Erythematous macules are common in inflammatory diseases of the superficial dermis, such as allergies.
Petechiae are pin-point macules caused by haemorrhage of less than 1 cm in diameter.
www.rvc.ac.uk /review/Dermatology/Lesions/macules.htm   (101 words)

 The spectrum and evolution of phenotypic findings in PTEN mutation positive cases of Bannayan-Riley-Ruvalcaba syndrome ...
haemangioma, or intestinal polyp), and penile macules in males.
macules of the penile shaft were first detected at the age of
Penile macules are perhaps the most distinctive and potentially valuable diagnostic feature of this syndrome.
jmg.bmjjournals.com /cgi/content/full/38/1/52   (4119 words)

 Macules definition - Medical Dictionary definitions of popular medical terms   (Site not responding. Last check: 2007-10-04)
Macules: Small circumscribed changes in the color of skin that are neither raised (elevated) nor depressed.
Dermatologists (and other physicians) call small flat skin spots on the skin macules, as opposed to papules which are small solid bumps that rise up above the surrounding skin and vesicles which are small blisters that contain fluid (before they burst).
The word macule comes from the Latin macula meaning a small spot or blemish.
www.medterms.com /script/main/art.asp?articlekey=14073   (179 words)

 Common hyperpigmentation disorders in adults: Part I. Diagnostic approach, Cafe au Lait Macules, diffuse ...
Cafe au lait (coffee with milk) macules can be congenital, or they may develop in childhood.
Cafe au lait macules may be a sign of neurofibromatosis.
Consultation with a geneticist may be prudent because neurofibromatosis is an autosomal dominant condition, although spontaneous mutations cause 50 percent of cases.
www.findarticles.com /p/articles/mi_m3225/is_10_68/ai_110488908   (873 words)

 Pigmentary Diseases - New Treatments, May 2, 2006
Papulosquamous lesions are the most common presentation and present initially as a reddish macule, which evolves into either a hypopigmented or a hyperpigmented superficial scaly plaque.
Cafe au lait macules are well-circumscribed, 0.2- to 10-cm, uniform, well-circumscribed, brown macules with irregular margins.
Epidermal hypermelanosis in patients with melasma appears tan-to-brown on physical examination, and the macules are accentuated by a Wood's lamp.
www.ccspublishing.com /journals3a/pigmentary_diseases.htm   (1505 words)

 DermAtlas: Online Dermatology Image Library dermatology image,neurofibromatosis,café au lait spot,neurofibromatosis, ...   (Site not responding. Last check: 2007-10-04)
The patient has a history of a segmental distribution of café-au-lait macules and freckling involving the right abdomen and right inguinal area, which were first noted at six months of age.
The microdeletion was present in a mosaic pattern in the café-au-lait spot macules, but was absent from normal skin as well as peripheral blood.
This 12-year-old girl had multiple café au lait macules and a large spongy subcutaneous tumor of the right side of the face.
dermatlas.med.jhmi.edu /derm/result.cfm?Diagnosis=83   (1951 words)

 Oral melanotic macules in patients infected with human immunodeficiency virus.
Oral melanotic macules in patients infected with human immunodeficiency virus.
In two patients the macules appeared during the administration of zidovudine.
Two of these macules also contained Epstein-Barr virus, and in one case normal oral mucosa was examined and also contained Epstein-Barr virus in the epithelial cells.
www.aegis.com /aidsline/1991/apr/M9140280.html   (511 words)

 The Use of Lasers in the Pediatric Population
Port wine stains (PWSs) are congenital vascular malformations composed of ectatic capillary-like vessels in the papillary dermis that occur in 0.3% of newborns.
Café au lait macules (CALMs) are benign hyperpigmented areas, present at birth in 2% of all newborns (up to 1/3 of fl neonates).
The exact etiology of the macules is unknown.
www.skintherapyletter.com /2005/10.8/2.html   (2069 words)

 Treatment For Macules Caused By Acne - Amazing Acne Guide   (Site not responding. Last check: 2007-10-04)
Researchers have discovered a tiny, unseen parasite that is believed to be a major cause of acne and other skin problems.
Here is the latest information on treatment for macules caused by acne.
Macules are essentially the final stage of most inflamed acne lesions.
www.amazingacneguide.com /treatment-for-macules-caused-by-acne.html   (517 words)

 eMedicine - Tinea Versicolor : Article Excerpt by: Craig G Burkhart, MD, MPH   (Site not responding. Last check: 2007-10-04)
Background: Tinea versicolor is a common, benign, superficial cutaneous fungal infection usually characterized by hypopigmented or hyperpigmented macules and patches on the chest and the back.
In the case of hypopigmentation, tyrosinase inhibitors (resulting from the inhibitory action of tyrosinase of dicarboxylic acids formed through the oxidation of some unsaturated fatty acids of skin surface lipids) competitively inhibit a necessary enzyme of melanocyte pigment formation.
In hyperpigmented macules in tinea versicolor, the organism induces an enlargement of melanosomes made by melanocytes at the basal layer of the epidermis.
www.emedicine.com /derm/byname/tinea-versicolor.htm   (618 words)

 What is Acne?   (Site not responding. Last check: 2007-10-04)
Macule—A macule is the temporary red spot left by a healed acne lesion.
A macule may persist for days to weeks before disappearing.
When a number of macules are present at one time they can contribute to the "inflamed face" appearance of acne.
www.skincarephysicians.com /acnenet/acne.html   (1130 words)

Tinea versicolor (also called pityriasis versicolor) is a mild, chronic, superficial fungal infection of the skin caused by Malassezia furfur.
The disease is usually asymptomatic and it typically involves the upper trunk particularly in young individuals living in warm, humid environment.
The typical lesions of TV consist of hypopigmented to brownish, well-defined, small, round to oval macules with fine, powdery scales on their surface.
dermind.tripod.com /tv.htm   (758 words)

 Indian Pediatrics - Editorial
Skin examination revealed three hypopigmented macules resembling ash leaves.
Ash leaf macule on the anterior aspect of right shoulder.
Hypopigmented macules are seen in 50% of <2 year old.
www.indianpediatrics.net /june2002/june-593.htm   (199 words)

 Laugier-Hunziker syndrome: an important differential diagnosis for Peutz-Jeghers syndrome -- Lampe et al. 40 (6): 77 -- ...
Figure 1 Photograph of the proband demonstrating multiple lenticular hyperpigmented macules on his lips as well as small melanotic macules on his fingerpulps.
macules of 2–5 mm diameter which can be slate to dark
Pigmented macules are a common finding on skin examination.
jmg.bmjjournals.com /cgi/content/full/40/6/e77   (1974 words)

 DermAtlas: Online Dermatology Image Library dermatology image,cytomegalovirus infection (CMV),blueberry muffin lesions
disseminated 0.5-1 cm reddish purple macules and papules
This term newborn was covered with reddish purple 0.5-1 cm nonblanching macules and papules.
On exam he was found to have microcephaly and hepatomegaly.
dermatlas.med.jhmi.edu /derm/result.cfm?Diagnosis=-407168790   (832 words)

 Macule - Wikipedia, the free encyclopedia
It is flat and can only be seen and not felt.
The macule is noted by a change in color of the skin.
It may be brown, blue, red or exhibit a lesser pigment or an absence of pigment.
en.wikipedia.org /wiki/Macule   (86 words)

 Get Rid of Pimples Naturally, Home Remedy for Acne   (Site not responding. Last check: 2007-10-04)
Atrophic macules, a form of scarring most common in Caucasians, are soft with a slightly wrinkled base.
Blood vessels just below the surface of the scar may make them appear purplish when they are recent, but this discoloration may fade over time to a pale ivory.
Atrophic macules are usually small when they occur on the face, but may be a centimeter or larger elsewhere on the body.
www.acnesource.org /facts_acne-scars_atrophic-macules.htm   (90 words)

 Clinical Trial: Effect of Cold Air Cooling on the Incidence of Post Inflammatory Hyperpigmentation Following Laser ...
We assumed that epidermal cooling may minimize the non-specific injury to the epidermis caused during laser irradiation, leading to the decreased incidence of post inflammatory hyperpigmentation.
Treatment of acquired bilateral nevus of Ota-like macules (Hori's nevus) using a combination of scanned carbon dioxide laser followed by Q-switched ruby laser.
Raulin C, Grema H. Single-pass carbon dioxide laser skin resurfacing combined with cold-air cooling: efficacy and patient satisfaction of a prospective side-by-side study.
clinicaltrials.gov /ct/show/NCT00287001   (361 words)

 IngentaConnect Pigmented penile macules   (Site not responding. Last check: 2007-10-04)
There are two opposing schools of thought regarding the management of pigmented penile macules.
Allan and Spitz, as well as Pack and Davis, are of the opinion that almost all pigmented naevi present on the palms, soles and genitalia are junctional naevi and have a higher incidence of malignant change and, therefore, should be removed.
The purpose of this paper is to review the literature regarding the natural history, risk of melanoma development on the penis and the management of cases presenting with pigmented penile macules.
www.ingentaconnect.com /content/rsm/std/2004/00000015/00000011/art00002   (238 words)

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