
	Where results make sense

Topic: Malignant hyperthermia

Related Topics

Neuroleptic malignant syndrome

Creatine

Rhabdomyolysis

Allergic reactions during anaesthesia

Postoperative nausea and vomiting

Creatine Phosphokinase

Creatine kinase

Myocarditis

Leptospirosis

Immunodeficiency

Carnegie, Pennsylvania

Latex allergy

Muscle

Anesthesia

Drugs

In the News (Sun 6 Dec 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Malignant Hyperthermia - Health EncyclopediaNews Story - WMAQ \| Chicago
		Malignant hyperthermia is an inherited disease that causes a rapid rise in body temperature (fever) and severe muscle contractions when the affected person?undergoes general?anesthesia.
		Malignant hyperthermia is often noted for the first time after a patient is given anesthetic drugs during a surgical procedure.
		Malignant hyperthermia is an autosomal dominant trait, meaning it requires only one parent carrying the disease for a child to?inherit the condition.
	www.nbc5.com /encyclopedia/6861832/detail.html (792 words)

	Malignant hyperthermia - Wikipedia, the free encyclopedia
		Malignant hyperthermia (MH or MHS for "malignant hyperthermia syndrome", or "malignant hyperpyrexia due to anesthesia") is a life-threatening condition resulting from a genetic sensitivity of skeletal muscles to volatile anaesthetics and depolarizing neuromuscular blocking drugs that occurs during or after anaesthesia.
		Malignant hyperthermia is caused in a large proportion (25-50%) of cases by a mutation of the ryanodine receptor (type 1) on sarcoplasmic reticulum (SR), the organelle within skeletal muscle cells that stores calcium (Gillard et al., 1991).
		Research into malignant hyperthermia was limited until the discovery of "porcine stress syndrome" in pigs, a condition in which stressed pigs develop "pale, soft, exudative" flesh (a manifestation of the effects of malignant hyperthermia) rendering their meat unmarketable at slaughter.
	en.wikipedia.org /wiki/Malignant_hyperthermia (979 words)

	Malignant hyperthermia - quetiapine fumarate with malignant hyperthermia
		Malignant hyperthermia (MH or MHS for "malignant hyperthermia syndrome") is a life-threatening condition resulting from a genetic sensitivity of skeletal muscles to volatile anaesthetics and depolarizing neuromuscular blocking drugs that occurs during or after anaesthesia.
		The dog malignant hyperthermia result is excessive release of calcium, which is reabsorbed into the SR in a futile cycle; this process consumes large amounts of ATP (adenosine triphosphate), the main cellular energy carrier, and generates the excessive heat (hyperthermia) that is the hallmark of the disease.
		Research into malignant hyperthermia was limited until the discovery of "porcine malignant hyperthermia dupuis stress syndrome" in pigs, a condition in which stressed pigs develop "pale, soft, exudative" flesh (a manifestation of the effects of malignant hyperthermia) rendering their meat unmarketable at slaughter.
	www.medicalgeo.com /Med-Diseases-M---Mu/Malignant-hyperthermia.html (1086 words)

	Lifespan's A - Z Health Information Library - Malignant hyperthermia (Site not responding. Last check: 2007-10-14)
		Malignant hyperthermia is an inherited disease that causes a rapid rise in body temperature (fever) and severe muscle contractions when the affected person undergoes general anesthesia.
		Malignant hyperthermia is often noted for the first time after a patient is given anesthetic drugs during a surgical procedure.
		Malignant hyperthermia is an autosomal dominant trait, meaning it requires only one parent carrying the disease for a child to inherit the condition.
	www.lifespan.org /adam/healthillustratedencyclopedia/1/001315.html (591 words)

	AllRefer Health - Malignant Hyperthermia (Hyperpyrexia - Malignant, Hyperthermia - Malignant)
		Malignant hyperthermia is a group of inherited muscle problems characterized by muscle breakdown following certain stimuli -- such as anesthesia, extremes of exercise (particularly in hot conditions), fever, or use of stimulant drugs.
		Malignant hyperthermia is inherited as an autosomal dominant trait (it requires only one affected parent for a child inherit the condition).
		Malignant hyperthermia is often noted for the first time during administration of anesthesia.
	health.allrefer.com /health/malignant-hyperthermia-info.html (415 words)

	FASEB Breakthroughs in Bioscience - Making Anesthesia Safer: Unraveling the Malignant Hyperthermia Puzzle
		Because malignant hyperthermia occurs uncommonly and unpredictably, the manufacturer of dantrolene and its clinical research manager begin a multiple center study by enlisting anesthesiologists from 65 institutions in the United States and Canada.
		In the developed world, malignant hyperthermia hotlines are established and staffed by anesthesiologists who volunteer their time to provide continuous expert medical advice to medical professionals confronted with malignant hyperthermia crises, which could occur anywhere that anesthetic agents are given.
		All pig malignant hyperthermia is linked to the presence of a cysteine rather than an arginine amino acid produced by the mistaken substitution of a C (cytosine) for a T (thymine) nucleic acid in the pig DNA.
	opa.faseb.org /pages/PublicEducators/mh (4674 words)

	Malignant hyperthermia after anaesthesia
		Malignant hyperthermia occurs once in 15 000 cases in children (up to 2 years of age) and once in 50 000 cases in adults (more than 50 years of age) after undergoing common anaesthesia.
		Pathogenesis of malignant hyperthermia is explained with abnormal circulation of calcium in muscle cells - the endoplasmatic reticulum releases a great amount of the ion and the diffusion back is reduced.
		The switch-on substances for malignant hyperthermia are all inhalatory anaesthetics, muscle relaxants (especially suxinylcholin), amid local anaesthetics, possibly ketamin, stress reactions.
	www.med.primasoft.bg /versions/englishpages/medical_science/articles/malignant_hyperthermia.htm (576 words)

	Malignant hyperthermia - SJMMC, Ann Arbor, Michigan MI
		Malignant hyperthermia is a rare, inherited (genetic) disorder that is potentially fatal.
		People with a family history of malignant hyperthermia or a medical history that includes conditions such as Duchenne muscular dystrophy, neuroleptic malignant syndrome, and other diseases that affect the muscles should be considered at risk and should be tested.
		People at risk of malignant hyperthermia may have a family history of unexplained death during anesthesia, an unexpected serious complication during anesthesia, breakdown of muscle tissue during exercise, muscle disorders, heatstroke, or heat intolerance.
	www.sjmercyhealth.org /16643.cfm (425 words)

	Medical Dictionary: Malignant hyperthermia - WrongDiagnosis.com
		Malignant hyperthermia: usually inherited reaction to general anesthesia manifested as a sudden, rapid rise in temperature, hypermetabolism, and skeletal muscle rigidity; mutation is in the calcium release channel of skeletal muscle sarcoplasmic reticulum.
		Malignant hyperthermia : usually inherited reaction to general anesthesia manifested as a sudden, rapid rise in temperature, hypermetabolism, and skeletal muscle rigidity; mutation is in the calcium release channel of skeletal muscle sarcoplasmic reticulum.
		Malignant hyperthermia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
	www.wrongdiagnosis.com /medical/malignant_hyperthermia.htm (421 words)

	malignant hyperthermia (Site not responding. Last check: 2007-10-14)
		Malignant mesothelioma is a disease that is caused by exposure to asbestos and is fatal.
		Malignant Hyperthermia (MH) is a lifethreatening, acute pharmacogenetic...
		Malignant melanoma (MM) is a malignant neoplasm of epidermal melanocytes.
	cash-in-now.com /malignant-hyperthermia (4405 words)

	JS Online:Test would help detect malignant hyperthermia
		If a malignant hyperthermia survivor has one of 16 mutations the test detects - and roughly a third are expected to - then scientists should be able to tell if his or her relatives inherited the condition.
		Malignant hyperthermia occurs when certain anesthesia drugs - including a family of inhaled gases, such as isoflurane and sevoflurane, that are top choices for children - trigger a life-threatening attack in a genetically susceptible patient.
		Malignant hyperthermia once killed most victims, but today death is rare because anesthesiologists watch for early signs and usually reverse symptoms with quick use of a drug called dantrolene.
	www.jsonline.com /alive/news/mar04/212901.asp (945 words)

	NMSIS - Neuroleptic Malignant Syndrome Information Service (Site not responding. Last check: 2007-10-14)
		Hyperthermia may be observed in patients with thyrotoxicosis and pheochromocytoma, which can be distinguished from NMS by the absence of rigidity.
		Volatile anesthetics and succinylcholine are associated with malignant hyperthermia during surgery, which can be confused with NMS if neuroleptics are administered.
		Central dopamine hypoactivity and the pathogenesis of the neuroleptic malignant syndrome.
	www.nmsis.org /general_information.shtml (2652 words)

	Malignant hyperthermia and the otolaryngologist - Original Article Ear, Nose & Throat Journal - Find Articles
		Malignant hyperthermia is a rare disorder that can occur in patients who are sensitive to certain agents used in general anesthesia.
		Although malignant hyperthermia has been well described in the literature, there continue to be conflicting recommendations from different sources regarding its prevention.
		In addition to reviewing the prevention, diagnosis, and management of malignant hyperthermia, we also report our experience in anesthetizing a patient who had a history of malignant hyperthermia--a case that illustrates the uncertainty that can complicate the management of such patients.
	www.findarticles.com /p/articles/mi_m0BUM/is_6_82/ai_104081129/pg_2 (396 words)

	Official Dantrium Intravenous FDA information, side effects and uses.
		Experimental results in malignant hyperthermia susceptible swine show that prophylactic administration of intravenous or oral dantrolene prevents or attenuates the development of vital sign and blood gas changes characteristic of malignant hyperthermia in a dose related manner.
		Dantrium Intravenous should be administered by continuous rapid intravenous push as soon as the malignant hyperthermia reaction is recognized (i.e., tachycardia, tachypnea, central venous desaturation, hypercarbia, metabolic acidosis, skeletal muscle rigidity, increased utilization of anesthesia circuit carbon dioxide absorber, cyanosis and mottling of the skin, and, in many cases, fever).
		The effective dose to reverse the crisis is directly dependent upon the individual's degree of susceptibility to malignant hyperthermia, the amount and time of exposure to the triggering agent, and the time elapsed between onset of the crisis and initiation of treatment.
	www.drugs.com /pro/dantrium_intravenous.html (3305 words)

	Malignant Hyperthermia Specialised Areas
		It is therefore important that everyone caring for a woman at risk of malignant hyperthermia, or the partner of a man susceptible to malignant hyperthermia, knows that the risk is there.
		However, it is thought to be important to reduce the stress to the body during labour for women and babies at risk of malignant hyperthermia.
		When a woman susceptible to malignant hyperthermia starts in labour, her lead maternity carer should notify the operating theatre and the on-call specialist anaesthetist.
	www.midcentral.co.nz /hospital/Mal-Hyper/MalH-Spec_copy(1).htm (1066 words)

	Hyperthermia Treatment Page
		Hyperthermia has since inhabited a strange in-between land of having its value recognized, and being used sporadically in some cancer centers, while ignored or underutilized by most oncologists around the country, and largely unknown to the public.
		Another source claims that "in all clinical studies hyperthermia has been shown to improve local control to some extent and has never worsened it." Despite difficulties in increasing human tumor temperatures, recent clinical trials have shown that a combination of hyperthermia with radiation is superior to radiation alone in controlling many human tumors.
		Hyperthermia improves the therapeutic index of TBI (total body irradiation), not only by increased neoplastic cell kill, but also by inhibiting the expression of radiation induced damage to the normal cell population.
	www.redblufftumor.com /hyperthermia.htm (1567 words)

	Malignant Hyperthermia
		This unusual reaction, malignant hyperthermia, occurs in genetically predisposed patients, who have a disease of their skeletal muscle, which may otherwise be clinically silent.
		This reaction is known as malignant neuroleptic syndrome.
		Willner was on the advisory board of the Malignant Hyperthermia Association of the United States and has published research and clinical papers about these conditions.
	www.bergenneurology.com /malignant_hyperthermia.htm (157 words)

	Malignant hyperthermia: update on susceptibility testing.
		Malignant hyperthermia (MH) is a pharmacogenetic clinical syndrome that manifests as a hypermetabolic crisis when a susceptible individual is exposed to an anesthetic triggering agent.
		Detection of a novel ryanodine receptor subtype 1 mutation (R328W) in a malignant hyperthermia family by sequencing of a leukocyte transcript.
		Caffeine and halothane sensitivity of intracellular Ca2+ release is altered by 15 calcium release channel (ryanodine receptor) mutations associated with malignant hyperthermia and/or central core disease.
	www.tripdatabase.com /spider.html?itemid=284426 (337 words)

	InteliHealth:
		Malignant hyperthermia occurs when a rare, inherited muscle abnormality causes a severe and sometimes fatal reaction to a dose of anesthetics.
		Although malignant hyperthermia most often occurs during or after surgery, it can occur wherever anesthetic medications are used, such as in emergency rooms, dental offices, surgeons' offices and intensive care units.
		Symptoms of malignant hyperthermia usually occur within the first hour after a medication that can trigger the disorder is administered, although the symptoms can be delayed for up to 12 hours.
	www.intelihealth.com /IH/ihtIH/WSIHW000/9339/24695.html (1412 words)

	CIGNA - Neuroleptic Malignant Syndrome
		Neuroleptic malignant syndrome is a rare but potentially life-threatening reaction to the use of almost any of a group of antipsychotic drugs or major tranquilizers (neuroleptics).
		Some clinicians believe that neuroleptic malignant syndrome may be related to malignant hyperthermia, a genetic disorder characterized by an abnormal reaction to anesthesia drugs.
		Malignant hyperthermia is a genetic disorder characterized by an abnormal response to muscle relaxants and general anesthesia drugs.
	www.cigna.com /healthinfo/nord763.html (1870 words)

	Malignant hyperthermia (Site not responding. Last check: 2007-10-14)
		Malignant hyperthermia is a peculiar disorder of muscle metabolism which is known to occur in man, swine, and many other mammalian species.
		What happens in malignant hyperthermia is termed an "uncoupling" of oxidative phosphorylation.
		The metabolic energy plant is turned on to its maximum setting, but largely (but not completely) divorced from the normal "connection" to muscular motor activity.
	netpet.batw.net /articles/mh.html (288 words)

	CIGNA - Malignant Hyperthermia
		Malignant hyperthermia is an autosomal dominant genetic condition caused by an abnormality in one of several genes that regulate the release of calcium from muscle.
		The incidence of malignant hyperthermia is not known because many people who have it are not aware of the diagnosis until they have an adverse reaction to anesthesia.
		Malignant hyperthermia is diagnosed by the caffeine/halothane contracture test (CHCT) that is also known as the in vitro contracture test (IVCT).
	www.cigna.com /healthinfo/nord8.html (1837 words)

	Malignant hyperthermia (Disease)... Fort Lauderdale, Florida (Site not responding. Last check: 2007-10-14)
		Malignant hyperthermia can be brought on in susceptible people by anesthesia, extremes of exercise (particularly in hot conditions), fever or use of stimulant drugs.
		Episodes of malignant hyperthermia may be prevented by giving dantrolene sodium before anesthesia.
		For an episode of malignant hyperthermia, antipyretics (fever-reducing medications such as acetaminophen) and a cooling blanket can help reduce acutefever.
	www.browardhealth.org /17508.cfm (666 words)

	Carilion - Malignant Hyperthermia
		Malignant Hyperthermia (MH) is an inherited disorder in which affected individuals do not react appropriately to certain general anesthetia drugs such as halothane, cyclopropane, and the muscle relaxant succinylcholine.
		Malignant Hyperthermia is inherited as an autosomal dominant trait.
		Once a person is diagnosed with Malignant Hyperthermia, their relatives should be tested to determine if they also have the disorder.
	www.carilion.com /kbase/htm/nord/8/nord8.htm (410 words)

	Malignant Hyperthermia
		Malignant Hyperthermia may be related to abnormally high levels of calcium in muscle tissue (sarcoplasmic tissue).
		Malignant Hyperthermia patients should be certain that the drug dantrolene sodium is available at a hospital where they are to undergo surgery.
		Scientists studying Malignant Hyperthermia are attempting to develop a less invasive diagnostic test for this disorder and are also trying to develop more effective therapies for the syndrome.
	hw.healthdialog.com /kbase/nord/nord8.htm (1461 words)

Try your search on: Qwika (all wikis)