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Topic: Mammalian

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In the News (Wed 17 Jul 19)

  Mammalian Biology - Elsevier
Its scope covers all aspects of mammalian biology, such as anatomy, morphology, palaeontology, taxonomy, systematics, molecular biology, physiology, neurobiology, ethology, genetics, reproduction, development, evolutionary biology, domestication, ecology, faunistics, wildlife biology, conservation biology, and the biology of zoo mammals.
To qualify for publication, a manuscript must contribute to the understanding of mammalian biology by presenting either new and original research data (as a full article or in short communication format) or a thorough review of a particular topic of mammalogical research.
Due to its wide range of topics, Mammalian Biology is primarily of interest to scientists working on the listed various fields of mammalogy but also to biologists and zoologists in general as well as to veterinarians and medical scientists.
www.elsevier.com /wps/find/journaldescription.cws_home/701782/description   (287 words)

  Extinction: A Climate Change Mammalian Population Collapse Mechanism
Application of modern reproductive physiology principles to the global mammalian extinctions at the end of the last ice age, which occurred during general greenhouse conditions and climatic oscillations, accounts for the elimination of primarily large mammals, and coeval dwarfing and skeletal abnormalities.
This paper outlines the sensitivity of mammalian reproduction systems to environmental heat, shows how heat is causing embryo failure, and explores the role of climatic warming in the global mammalian extinctions of 12,000-10,000 years ago, of which we are but the survivors.
Global mammalian extinctions of primarily large mammals, dwarfing, and skeletal abnormalities occurred during the abrupt and radical climate oscillations of the Pleistocene-Holocene transition at the end of the last ice age.
filebox.vt.edu /artsci/geology/mclean/Dinosaur_Volcano_Extinction/pages/grhskill.html   (6321 words)

 International Mammalian Genome Society Bylaws
The International Mammalian Genome Society provides opportunities for association and conference among students of mammalian genetics, encourages communication and publication of scientific knowledge, promotes education and research in mammalian genetics, and facilitates interaction between workers in mammalian genetics and related disciplines.
Mammalian Genome is the official journal of the Society and is published, owned and managed by Springer Verlag.
The editors of the IMGS journal Mammalian Genome are not eligible for election to President or Vice President of the IMGS.
www.imgs.org /bylaws.shtml   (2325 words)

 Prion - Wikipedia, the free encyclopedia
This "specificity" phenomenon may explain why transmission of prion diseases from one species to another (such as from sheep to cows or from cows to humans) is a rare event.
The mammalian prion proteins do not resemble the prion proteins of yeast in their amino acid sequence.
Nonetheless, the basic structural features (formation of amyloid fibers and a highly specific barrier to transmission between species) are shared between mammalian and yeast prions.
en.wikipedia.org /wiki/Prion   (1493 words)

 Comparative Mammalian Brain Collections
Also available are examples of stained sections from a wide variety of brains of special interest, including Humans, Chimpanzees, Monkeys, various Rodents and Carnivores, California Sealion, Florida Manatee, Big Brown Bat, American Badger, American Raccoon, Yellow Mongoose, Zebra, Cow, and the Atlantic Bottlenose Dolphin.
At any rate, we request that you identify them as from the University of Wisconsin and Michigan State Comparative Mammalian Brain Collections, as well as from those at the National Museum of Health and Medicine.
Also, we request that you refer to the Web Site where you obtained them, as well as the fact that preparation of all these images and specimens have been funded by the National Science Foundation, as well as by the National Institutes of Health.
www.brainmuseum.org   (255 words)

 Theoretical Biology and Medical Modelling | Full text | Size control in growing yeast and mammalian cells
In a recent publication it was claimed that cultured mammalian cells, in contrast to yeasts, maintain a constant size distribution in the population without a size checkpoint.
For example, mammalian cells can certainly grow without entering S phase [6]; and the very large cells of early embryos only develop a size control after a number of cycles [13].
The mammalian cells situation is far more difficult, but there is reasonable hope that it can be solved by methods of tracking individual cells such as fibroblasts by a semi-automatic method and measuring their dry mass by interferometry [15].
www.tbiomed.com /content/1/1/12   (2106 words)

 Mammalian Myotube Dedifferentiation Induced by Newt Regeneration Extract.
To investigate the causes underlying the lack of cellular plasticity in mammalian cells, we examined the effect of an extract derived from newt regenerating limbs on terminally differentiated mouse C2C12 myotubes.
Although cellular dedifferentiation has been demonstrated in newts, terminally differentiated mammalian cells are normally thought to be incapable of reversing the differentiation process (16, 17).
Based on the observation that newt myotubes reenter S phase when stimulated with serum or thrombin, whereas mammalian myotubes are refractory to these treatments (30-32), it was suggested that mammalian myotubes were intrinsically incapable of responding to dedifferentiation signals.
www.euchromatin.org /McGann01.htm   (2042 words)

 American Zoologist: Osmotically responsive genes: The mammalian osmotic response element (ORE)   (Site not responding. Last check: 2007-10-09)
Hyperosmotic accumulation of organic osmolytes is transcriptionally regulated: e.g., betaine in bacteria (e.g., Escherichia coli), glycerol in yeast (e.g., Saccharomyces cerevisiae), betaine in plants (e.g., Spinacea oleracea L.) and sorbitol, betaine, and inositol in cells of the mammalian renal medulla.
Renal medullary cells, among mammalian cells, are uniquely exposed to hyperosmotic stress; in these cells, hyperosmotic stress results in accumulation of sorbitol as one of the predominant osmolytes.
While mammalian extracellular fluid is strictly regulated at about one third the salt concentration of seawater (full-strength seawater == 1,000 mosmol), cells in the kidney of virtually any mammal are routinely exposed to two- to three-fold the salinity of seawater.
www.findarticles.com /p/articles/mi_qa3746/is_200109/ai_n8987493   (1377 words)

 Euchromatin as an Extensile Force within Mammalian Cell Nuclei.
Extremes of chromatin compaction and small nuclear size are often found within cells with a high degree of heterochromatin and reduced nuclear activity, such as mature erythrocytes, granulocytes, lymphocytes, and spermatids [1].
Certain mammalian cells are capable of a reversible nuclear enlargement and contraction in vitro, such as in T-lymphocytes during and after exposure to a mitogen such as phytohemagglutinin (PHA).
Euchromatin 10 nm microfibrils are a dynamic extensile force within the mammalian cell nucleus [11].
www.euchromatin.net /Hovsepian03.htm   (1541 words)

 Mammalian diving reflex -- Facts, Info, and Encyclopedia article   (Site not responding. Last check: 2007-10-09)
Mammalian diving reflex -- Facts, Info, and Encyclopedia article
This reflex puts the body into energy saving modus to maximize the time that can be spent under water.
This reaction is similar to the body's reaction to cold water (The act of wetting something by submerging it) dousing.
www.absoluteastronomy.com /encyclopedia/m/ma/mammalian_diving_reflex.htm   (243 words)

 Products - M-PER Mammalian Protein Extraction
Choose the complete cell lysis reagent with a detergent formulation that dissolves cell membranes at low concentrations, does not denature protein and is compatible with downstream assays.
For extraction with M-PER Reagent and Brand P lysis buffer, the cell suspensions were shaken for 5 minutes.The cell debris was removed by centrifugation at 13,000 rpm for 5 minutes and the supernatants were assayed for protein concentration by the BCA Method.
Mammalian FM2 cells were transiently transfected with a reporter construct containing the luciferase gene.
www.piercenet.com /Products/Browse.cfm?fldID=06010420   (416 words)

 Brain-Development Timeline For Mammalian Species   (Site not responding. Last check: 2007-10-09)
Key Component In Mammalian Telomere Maintenance Found (November 20, 2000) -- Research into telomere maintenance is at the forefront of the biomedical investigation of aging and cancer.
Gene Mutation Upsets Mammalian Biological Clock (April 24, 2000) -- Researchers have pinpointed the cause of a genetic mutation that switches a hamster's biological clock to a 20-hour day from the normal 24-hour...
The new model is an outgrowth of a mathematical equation first determined and reported in 1995 by Darlington, a behavioral statistician and professor of psychology, and Finlay, professor and chair of the Cornell Department of Psychology.
www.sciencedaily.com /releases/2001/07/010711060444.htm   (1096 words)

 Mammalian Phylogeny
The Mammalian tree below was redrawn from cladograms and information in the University of Arizona Tree of Life Web Site, from notes on mammalian diversity from the Berkeley Museum of Vertebrate Zoology and from a paper on mammalian phylogeny that appeared in
This last work was based on the analysis of both nuclear and mitochondrial genes and verifies mammalian groupings suggested by previous molecular analysis.
Mammalian mitogenomic relationships and the root of the eutherian tree
www.whozoo.org /mammals/mammalianphylo.htm   (232 words)

 Melvin DePamphilis Lab - Current Research in DNA Replication
Therefore, we have focused our attention on how mammalian cells determine where they will initiate DNA replication, and how this process is regulated through changes in the ORC/chromatin complex.
In mammalian cells, the affinity of Orc1 for chromatin is cell cycle dependent.
To this end, we are identifying the factors that regulate ORC binding and dissociation from chromosomes and the factors that determine sequence-specific binding of Orc proteins.
depamphilislab.nichd.nih.gov /current_research_DNA.html   (1457 words)

 Amazon.ca: Books: Mammalian Neuroendocrinology   (Site not responding. Last check: 2007-10-09)
Mammalian Neuroendocrinology presents a concise examination of how the nervous and endocrine systems interact to regulate physiological processes.
Mammalian Neuroendocrinology is excellent for students and professionals in neuroendocrinology, neuroscience, endocrinology, reproduction studies, and animal sciences.
Uses a comparative mammalian approach with rodents, domesticated ungulates, and primates, either human or monkey.
www.amazon.ca /exec/obidos/ASIN/0849387574   (301 words)

 Live-Cell Microscopy Environmental Control for Mammalian Specimens
The ability to observe and quantify mammalian live-cell phenomena is made possible largely due to the recent advancements in technological tools for imaging.
Because the correlation between in vitro and in vivo phenomena is paramount for mammalian live-cell biology, it is of the utmost importance to accurately simulate the host conditions of the isolated specimen during live-cell microscopy.
Therefore, it follows that the accuracy of the data and thus the strength of the data's support should not be weakened through the data acquisition process.
www.bioptechs.com /lc_basics.html   (2305 words)

 American Zoologist: Mammalian feeding motor patterns   (Site not responding. Last check: 2007-10-09)
The relative uniformity of the mammalian jaw-closer motor patterns during this chewing behavior, as characterized by electromyography (EMG), is striking.
In contrast to the relative uniformity in motor patterns, the anatomical diversity of jaw systems is impressive and probably reflects the adaptation to diet.
Part 3 concentrates on the area of ontogeny of the mammalian feeding patterns, and in part 4, the influence of occlusal forces on the masticatory motor pattern is discussed.
www.findarticles.com /p/articles/mi_qa3746/is_200112/ai_n9005447   (1359 words)

 Mammalian septin Sept2 modulates the activity of GLAST, a glutamate transporter in astrocytes -- Kinoshita et al. 9 ...
Hsu, S.C., Hazuka, C.D., Roth, R., Foletti, D.L., Heuser, J. and Scheller, R.H. (1998) Subunit composition, protein interactions, and structures of the mammalian brain sec6/8 complex and septin filaments.
Kartmann, B. and Roth, D. (2001) Novel roles for mammalian septins: from vesicle trafficking to oncogenesis.
Surka, M.C., Tsang, C.W. and Trimble, W.S. (2002) The mammalian septin MSF localizes with microtubules and is required for completion of cytokinesis.
www.genestocellsonline.org /cgi/content/full/9/1/1   (5715 words)

 Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in ...
The purpose of the present investigation was to determine whether mammalian target of rapamycin (mTOR)-mediated signalling and some key regulatory proteins of translation initiation are altered in skeletal muscle during the immediate phase of recovery following acute resistance exercise.
Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein synthesis.
A direct linkage between the phosphoinositide 3-kinase-akt signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
jp.physoc.org /cgi/content/full/553/1/213   (5705 words)

 Mammalian Meiotic Telomeres: Protein Composition and Redistribution in Relation to Nuclear Pores -- Scherthan et al. 11 ...
Mammalian Meiotic Telomeres: Protein Composition and Redistribution in Relation to Nuclear Pores -- Scherthan et al.
the protein composition of mammalian meiotic telomeres is undetermined.
Shore, D., and Nasmyth, K. Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements.
www.molbiolcell.org /cgi/content/full/11/12/4189   (7588 words)

 Capture of DNA Sequences at Double-Strand Breaks in Mammalian Chromosomes -- Lin and Waldman 158 (4): 1665 -- Genetics
MAMMALIAN genomes suffer a variety of types of damage each day.
a mammalian chromosome is the most complete such study to date.
of microsatellites at DSBs in a mammalian genome (
www.genetics.org /cgi/content/full/158/4/1665   (4917 words)

 Mammalian Expression Vectors
Contains SV40 promoter and enhancer sequences resulting in strong expression of CAT in many mammalian cells.
Designed to promote constitutive expression of cloned DNA inserts in mammalian cells.
Protocol: pCI and pSI Mammalian Expression Vectors, TB206
www.promega.com /vectors/mammalian_express_vectors.htm   (411 words)

 Functional Genomics of Sleep and Circadian Rhythm: Invited Review: Regulation of mammalian circadian clock genes -- ...
Mammalian circadian clock genes and the effect of mutations on period length in constant darkness and on the corresponding protein
Rapid down-regulation of mammalian Period genes during behavioral resetting of the circadian clock.
Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.
jap.physiology.org /cgi/content/full/92/3/1348   (6023 words)

 Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System -- Baumann and Pham-Dinh 81 (2): 871 -- ...
NI-35/250 proteins are transmembrane proteins enriched in mammalian myelin CNS and oligodendrocytes (105).
Mammalian species acquire their full complement of cortical neurons during the first half of gestation.
In the mammalian cortex, both neurons and glia arise from the proliferating neuroepithelial cells of the telencephalic ventricular
physrev.physiology.org /cgi/content/full/81/2/871   (10087 words)

 The spatio-temporal organization of DNA replication sites is identical in primary, immortalized and transformed ...
Based on the number, size, shape and distribution of fluorescent foci, the replication sites were classified into five major types of patterns, which were similar in all cell lines.
Stability and nuclear distribution of mammalian replication protein A heterotrimeric complex.
Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesis.
jcs.biologists.org /cgi/content/full/115/21/4037   (7871 words)

 Hot Topics! Stable Expression of Mammalian Cells with Constructs that Synthesize siRNAs
Interest in RNA interference (RNAi), a phenomenon in which introduction of dsRNA leads to gene-specific silencing, has recently exploded due to its widespread use in gene function studies.
Because siRNAs seem to be capable of distinguishing between target mRNAs with a single base mismatch, stably expressed siRNAs may be able to knockdown expression of mutant alleles of oncogenes or tumor suppressor genes without affecting expression of the wild-type allele.
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells.
www.ambion.com /techlib/hottopics/pSUPER_04242002.html   (882 words)

 Key Component In Mammalian Telomere Maintenance Found   (Site not responding. Last check: 2007-10-09)
The association of Ku with the mammalian telomere was, though, a surprising discovery.
Ku works at the mammalian telomere in a functionally distinct manner from its action at double stranded breaks.
Understanding the surprising association of Ku with the mammalian telomere is a primary step in understanding the delicate balance of cellular growth control and the aberrations which lead to cancer.
www.sciencedaily.com /releases/2000/11/001120073646.htm   (453 words)

 G1N10 GenElute Mammalian Genomic DNA Miniprep Kit
The GenElute Mammalian Genomic DNA Purification Kit provides a simple and convenient way to isolate pure, high molecular weight DNA from a variety of mammalian sources.
Mammalian cells and tissues are lysed with a chaotropic salt
DNA is bound to the spin column membrane and the remaining lysate is removed by centrifugation.
www.sigmaaldrich.com /catalog/search/ProductDetail?ProdNo=G1N10&Brand=SIGMA   (180 words)

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