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Topic: Mastocytosis


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In the News (Thu 21 Aug 08)

  
 MedFriendly.com: Mastocytosis
Mastocytosis is an uncommon condition in which there is an abnormal increase in mast cells in various organs, most commonly the skin.
Mastocytosis in childhood is usually mild and the children tend to outgrow it.
Patients with mastocytosis are often advised by their doctors to avoid substances that lead to the release of mast cell mediators, which are types of chemicals that can cause allergic reactions.
www.medfriendly.com /mastocytosis.html   (4979 words)

  
 Mastocytosis
Mastocytosis is usually mild in children and they often outgrow it.
Mastocytosis was originally described by E. Nettleship and W. Tay.
Symptoms of mastocytosis in the stomach and intestine are: diarrhea and stomach pain.
www.mamashealth.com /masto.asp   (330 words)

  
 THE MERCK MANUAL--SECOND HOME EDITION, Mastocytosis in Ch. 185, Allergic Reactions
Mastocytosis is an abnormal accumulation of mast cells in the skin and sometimes in various other parts of the body.
Mastocytosis develops when mast cells increase in number and accumulate in tissues over a period of years.
If mastocytosis affecting the skin is suspected, a sample of skin tissue is removed and examined under a microscope for mast cells.
www.merck.com /mrkshared/mmanual_home2/sec16/ch185/ch185e.jsp   (568 words)

  
 Mastocytosis - systemic and diffuse Mastocytosis
Mastocytosis is a proliferation of Mast Cells in the skin and often in organs throughout the body.
Mastocytosis is a disorder characterized by mast cell proliferation and accumulation within various organs, most commonly the skin.
A form of mastocytosis in which the entire skin is thickened and leathery with generalized reddening and intense pruritus (itching) due to widespread infiltration of the skin with mast cells.
www.cosmeticsdiary.com /mastocytosis.htm   (663 words)

  
 Mastocytosis, NIAID Fact Sheet   (Site not responding. Last check: 2007-10-09)
Mastocytosis is a disorder in both children and adults.
The diagnosis of systemic mastocytosis is made when an increased number of abnormal mast cells is found during an examination of your bone marrow.
In cases in which mastocytosis is malignant, cancerous, or associated with a blood disorder, steroids and/or chemotherapy may be necessary.
www.niaid.nih.gov /factsheets/masto.htm   (737 words)

  
 Mast Cell Disease
Mastocytosis is a disease characterized by excessive accumulation of mast cells in different tissues and symptoms caused by the release of mast cell mediators.
Because of the association of mastocytosis with hematologic disease, plasma levels were measured for soluble KIT (sKIT) and soluble interleukin-2 receptor alpha chain (sCD25), which are known to be cleaved in part from the mast cell surface and are elevated in some hematologic malignancies.
Mastocytosis is a term used for a group of disorders characterized by abnormal growth and accumulation of tissue mast cells (MC) in one or more organ systems.
www.thedoctorsdoctor.com /diseases/mast_cell_disease.htm   (11126 words)

  
 NORD - National Organization for Rare Disorders, Inc.
Mastocytosis is a rare disorder characterized by abnormal accumulations of mast cells in skin, bone marrow, and internal organs such as the liver, spleen and lymph nodes.
Cases beginning during adulthood tend to involve the inner organs in addition to the skin whereas, during childhood, the condition is often marked by skin manifestations with minimal or no organ involvement.
The course and prognosis of mastocytosis in these patients are determined by this associated hematologic disorder.
www.rarediseases.org /search/rdbdetail_abstract.html?disname=Mastocytosis   (264 words)

  
 Mastocytosis Pediatric Information and Parent Support   (Site not responding. Last check: 2007-10-09)
It is our goal to provide a place where parents and caregivers of children with mastocytosis can come to learn, find support, and discover a safe place for their children to interact with other masto kids.
Mastocytosis is a rare disease whose cause remains unknown.
The symptoms of mastocytosis are caused by the excessive amounts of chemicals interacting with body tissue.
www.mastokids.org   (297 words)

  
 Mastocytosis
Mastocytosis is the term for a group of disorders caused by too many "mast cells".
Systemic mastocytosis is caused by the accumulation of mast cells in the tissues and can affect organs such as the liver, spleen, bone marrow, and small intestine.
An array of drugs is used to treat the symptoms of mastocytosis, including antihistamines (to prevent mast cell release of chemicals), and anticholinergics (to relieve intestinal cramping).
www.aocd.org /skin/dermatologic_diseases/mastocytosis.html   (668 words)

  
 Mastocytosis -- Facts, Info, and Encyclopedia article   (Site not responding. Last check: 2007-10-09)
Another sign of this disorder is high levels of certain mast-cell chemicals and proteins in a person's (The fluid (red in vertebrates) that is pumped by the heart) blood and sometimes in the (Liquid excretory product) urine.
Mast cells express a cell surface receptor termed c-kit ((Click link for more info and facts about CD117) CD117), which is the (A cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response) receptor for scf (stem cell factor).
No one is sure how many people have either type of mastocytosis, but mastocytosis generally has been considered to be an " (Click link for more info and facts about orphan disease) orphan disease" (orphan diseases affect 200,000 or fewer people in the United States).
www.absoluteastronomy.com /encyclopedia/m/ma/mastocytosis.htm   (945 words)

  
 Association of the Q576R polymorphism in the interleukin-4 receptor {alpha} chain with indolent mastocytosis limited to ...   (Site not responding. Last check: 2007-10-09)
Mastocytosis is often associated with activating mutations in Kit, the receptor for stem cell factor.
Clinical correlates of the presence of the Asp816Val c-kit mutation in the peripheral blood mononuclear cells of patients with mastocytosis Cancer.
Analysis of the surface expression of c-kit and occurrence of the c-kit Asp816Val activating mutation in T cells, B cells, and myelomonocytic cells in patients with mastocytosis.
www.bloodjournal.org /cgi/content/full/98/3/880   (1714 words)

  
 Olive Claysons Mastocytosis Help and Info page   (Site not responding. Last check: 2007-10-09)
Mast cell disease also called Mastocytosis is a condition where there is an increased number of mast cells in various organs.
The treatment for Mastocytosis is: HI blockers (antihistamines), H2 Blocker (such as cimetidine and ranitidine), Gastrocrom or Ketotifen (mast cell stabilizers--Ketotifen available in Mexico and Canada, not in the US) Aspirins or anti-inflammatory drugs (These can cause a severe attack-caution needed) Prednisone for malabsorption, or flare ups, Epinephrine for severe attacks, PUVA for the lesions.
Mastocytosis is a rare disease that many health care professionals are unfamiliar with.
www.inet-1.com /~ocsons   (1214 words)

  
 Introduction: Mastocytosis - WrongDiagnosis.com
Mastocytosis: Mastocytosis is a group of disorders in both children and adults caused by the presence of too many mast cells in a person's body.
Researching symptoms of Mastocytosis: Further information about the symptoms of Mastocytosis is available including a list of symptoms of Mastocytosis, or alternatively return to research other symptoms in the symptom center.
Statistics and Mastocytosis: Various sources and calculations are available in statistics about Mastocytosis, prevalence and incidence statistics for Mastocytosis, and you can also research other medical statistics in our statistics center.
www.wrongdiagnosis.com /m/mastocytosis/intro.htm   (288 words)

  
 Clinical Trial: Cause and Natural Course of Pediatric-Onset Mastocytosis
This study will evaluate children with mastocytosis, a disease of excessive mast cells in tissues such as skin and bone marrow, to identify the cause of the disease and describe its course.
Mastocytosis in infants and children is an unusual disease characterized by an excess of mast cells in tissues.
In pediatric onset mastocytosis, disease is usually localized to the skin and disease is considered to be of limited duration.
clinicaltrials.gov /ct/show/NCT00050193   (877 words)

  
 Mastocytosis: What It Is and How It's Diagnosed and Treated -- familydoctor.org   (Site not responding. Last check: 2007-10-09)
When an adult gets mastocytosis, a bone marrow biopsy may be needed to look for other blood diseases that might come along with the mastocytosis.
The best treatment for mastocytosis may be to stay away from the things that seem to trigger your symptoms.
Because mastocytosis can cause a severe allergy reaction in some people, it's a good idea to keep an emergency kit with you at all times so you can give yourself medicine to stop a bad reaction.
familydoctor.org /441.xml   (732 words)

  
 Mastocytosis   (Site not responding. Last check: 2007-10-09)
Mastocytosis - The distribution and quantitation of dermal mast cells have been studied in histological preparations from patients with mastocytosis.
MASTOCYTOSIS ``Mastocytosis is a disorder in both children and adults that is caused by the presence of too many mast cells in a person's body.
Chee-won Oh Mastocytosis, NIAID Fact Sheet ``Mastocytosis is a disorder in both children and adults that is caused by the presence of too many mast cells in a person's body.
www.edae.gr /mastocytosis.html   (1870 words)

  
 eMedicine - Mastocytosis, Systemic : Article by Koyamangalath Krishnan, MD, FRCP
The clinical symptoms and signs of systemic mastocytosis are due to the accumulation of these clonally derived mast cells in different tissues, including bone marrow, skin, the GI tract, the liver, and the spleen.
Diagnosis is mastocytosis, and morphology is abnormal mast cell infiltrate.
Diagnosis is mastocytosis, morphology is mast cell infiltrate, and the organ is the lymph nodes.
www.emedicine.com /med/topic1401.htm   (3844 words)

  
 Soluble stem cell factor receptor (CD117) and IL-2 receptor alpha chain (CD25) levels in the plasma of patients with ...
Systemic mastocytosis is a disease of mast cell proliferation that may be associated with hematologic disorders.
Mastocytosis is characterized by an increase in tissue mast cells, particularly in the skin, bone marrow, lymph nodes, liver,
Clinical correlates of the presence of the Asp816Val c-kit mutation in the peripheral blood mononuclear cells of patients with mastocytosis.
www.bloodjournal.org /cgi/content/full/96/4/1267   (4860 words)

  
 Paediatric mastocytosis -- Carter and Metcalfe 86 (5): 315 -- Archives of Disease in Childhood
Mastocytosis in infants and children is an unusual disease characterised
Mastocytosis and atopy: a study of 33 patients with urticaria pigmentosa.
Mastocytosis in infants and children: recognition of patterns of skin disease.
adc.bmjjournals.com /cgi/content/full/86/5/315   (2870 words)

  
 Mastocytosis FAQ   (Site not responding. Last check: 2007-10-09)
Mastocytosis is a rare disease characterised by an increase in mast cells number [1].
The cells react to 'triggers' (in food, for example) by releasing chemicals, which cause symptoms that depend on the part of the body where the mast cells are.
Mastocytosis was originally described by E. Nettleship (hence one of the German names, 'Nettleshipsche Krankheit') and W. Tay under the heading of 'Rare forms of Urticaria' in the British Medical Journal, 1869.
www.tbm.tudelft.nl /webstaf/ivob/masto/mastofaq.htm   (1276 words)

  
 Oklahoma Mastocytosis Society - Medical Information
Mastocytosis is a rare disorder that affects both children and adults.
The disease is presently divided into four categories: (1) Indolent Mastocytosis (the most common form); (2) Mastocytosis with an associated hematologic disorder; (3) Aggressive Mastocytosis; and (4) mast cell leukemia.
Mastocytosis is a rare incurable disease that can only be controlled symptomatically with the correct combination of medications and reduction of triggers.
www.okmastocytosis.org /medical.htm   (846 words)

  
 Mastocytosis definition - Medical Dictionary definitions of popular medical terms
Mastocytosis: A condition characterized by infiltration of mast cells into the tissues of the body.
Diffuse mastocytosis (also called diffuse cutaneous mastocytosis) -- The entire skin is thickened and leathery with generalized reddening and intense pruritus (itching) due to widespread infiltration of the skin with mast cells.
Medications for diffuse and systemic mastocytosis may include antihistamines, drugs to reduce stomach acid, migraine headache drugs for headache, and cromolyn for bowel symptoms.
www.medterms.com /script/main/art.asp?articlekey=32728   (372 words)

  
 FDG Positron Emission Tomography in Patients with Systemic Mastocytosis -- Zettinig et al. 179 (5): 1235 -- American ...
In this patient, aggressive systemic mastocytosis was associated with chronic myelomonocytic leukemia.
Diagnostic criteria and classification of mastocytosis: a consensus proposal.
Mastocytosis: magnetic resonance imaging patterns of marrow disease.
www.ajronline.org /cgi/content/full/179/5/1235   (1499 words)

  
 Urticaria pigmentosa (mastocytosis). DermNet NZ
Urticaria pigmentosa is the name given to a type of mastocytosis, in which there are brown patches on the skin due to abnormal collections of mast cells.
Rarely, systemic mastocytosis is due to malignancy and results in a form of leukaemia.
Telangiectasia eruptiva macularis perstans (TEMP) is a rare form of mastocytosis in which diffuse red patches occur associated with overlying telangiectasia (dilated capillaries).
dermnetnz.org /colour/urticaria-pigmentosum.html   (666 words)

  
 Oklahoma Mastocytosis Society
Mastocytosis is a rare disease in search of a cure.
Although the cause of Mastocytosis remains unknown to us, the disease results in a proliferation of mast cells in the skin and often in organs throughout the body.
The Oklahoma Mastocytosis Society is directly affiliated with The Mastocytosis Society, Inc., an international self-help and support group for sufferers of the disease, as well as for their families and caregivers.
www.okmastocytosis.org   (151 words)

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