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Topic: Matthew Meselson


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In the News (Fri 25 Dec 09)

  
 [No title]
Matthew Meselson and Franklin Stahl invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.
In the fall of 1960, Meselson accepted the position of associate professor of molecular biology at Harvard University, where he is currently the Thomas Dudley Cabot Professor of the Natural Sciences.
In 1957, Stahl and Meselson developed the technique of density gradient centrifugation and used it to prove that DNA was replicated in a semi-conservative way, as predicted by Watson and Crick in their 1953 paper.
www.dnaftb.org /dnaftb/concept_20/con20bio.html   (1180 words)

  
 Harvard Gazette: Matthew Meselson wins 2004 Lasker Award
In the 1990s, Meselson and his wife, medical anthropologist Jeanne Guillemin, visited the site with an investigative team, and showed that the deaths were actually caused by a cloud of anthrax released from a suspected biological weapons facility.
Currently, Meselson, along with Julian Perry Robinson of the University of Sussex in England, co-direct an effort to establish an international treaty that prohibits biological and chemical weapons.
Meselson and his colleagues theorize that the advantage of sex may lie in its ability to reduce what he calls "genetic parasites." These are pieces of DNA that multiply on their own and can cause genetic damage.
www.news.harvard.edu /gazette/2004/09.30/01-meselson.html   (1103 words)

  
 Meselson, Matthew Stanley   (Site not responding. Last check: 2007-10-20)
US molecular biologist who, with Franklin Stahl, confirmed that replication of the genetic material DNA is semiconservative (that is, the daughter cells each receive one strand of DNA from the original parent cell and one newly replicated strand).
Meselson was born in Denver, Colorado, and studied physical chemistry at the California Institute of Technology.
Meselson has also investigated the molecular biology of nucleic acids, the mechanisms of DNA recombination and repair, and the processes of gene control and evolution.
www.cartage.org.lb /en/themes/Biographies/MainBiographies/M/Meselson/1.html   (231 words)

  
 The Lasker Foundation | 2004 Special Achievement Award
Matthew Meselson has deciphered fundamental biological problems and has helped to prevent the manufacture and spread of biological and chemical weapons.
In 1958, Meselson (then a graduate student of Linus Pauling at the California Institute of Technology in Pasadena) and Franklin Stahl showed that DNA duplication produces two identical daughter molecules, each containing one parental and one newly formed strand.
Meselson and his colleagues have provided strong evidence that rotifers of the Class Bdelloidea, a group of tiny aquatic invertebrates, have evolved for tens of millions of years without sex - a conclusion that challenges current evolutionary thinking.
www.laskerfoundation.org /awards/library/2004sa_cit.shtml   (1252 words)

  
 [No title]   (Site not responding. Last check: 2007-10-20)
Meselson, whose trip to SE Asia had been financed by the leftist MacArthur Foundation, collected bees' feces (droppings) far away from any war zone, examined the material by electron microscopy and other methods, not surprisingly found some toxins in it, and not surprisingly found no man-made toxins attributable to Soviet weapons.
Meselson's attack zeroed in on the investigative work of a three-man team of CBW experts from the State and Defense department stationed in Thailand from Nov. 1983 to Oct. 1985.
Meselson said that the bees' "cleansing" flight was too high to be seen, but the Thai told US officials that he actually saw an estimated 10,000 bees in flight.
www.textfiles.com /drugs/beefeces   (1569 words)

  
 The Scientist : Chemist With A Conscience
Last month, the dapper and indefatigable Meselson was at it again, hosting a series of meetings with three top-ranking Soviet scientists from a biological weapons plant who challenged the Reagan administration’s view of an anthrax outbreak nine years ago in the Soviet city of Sverdlosk.
Meselson chose to concentrate on biological warfare, then an area in which the U.S. was waging a research and development contest with the Soviet Union.
At the time, Meselson’s only knowledge of the issue came from a CIA telephone call inviting him to attend a briefing to be held later that month on yellow rain.
www.the-scientist.com /article/display/8448   (1977 words)

  
 Cape Cod Times: World law sought for germ war (October 22, 2001)
Rather, Meselson is talking about international law - a law that would consider individuals who engage in biological warfare guilty of a "crime against humanity," and hence subject to arrest in any nations backing the law.
Meselson also thinks it is too soon to reject the possibility that domestic rather than foreign terrorists may be responsible for the anthrax incidents.
Meselson also is involved in an effort by the Department of Defense to collaborate with Russian scientists in reducing potential threats from biological weapons.
www.capecodonline.com /special/terror/terrornews/worldlaw22.htm   (780 words)

  
 Anthrax
By 1991, when Matthew began recruiting the Sverdlovsk team, I was well immersed in the details of this new problem and had made several trips to the Soviet Union, although none with the purpose and potential of this foray.
Matthew's commitment to discovering the Sverdlovsk epidemic's cause goes back to 1980, when he was consulted by the CIA after news of the event leaked to the West.
Matthew Meselson and U. government BW experts at the army's Dugway Proving Ground, who better understood the basic aerodynamics involved in such estimates, reckoned that as little as a gram of aerosolized anthrax, with its trillion spores, could have caused the Sverdlovsk outbreak.
partners.nytimes.com /books/first/g/guillemin-anthrax.html   (3725 words)

  
 Dept of MCB, Harvard U: Faculty and Research - Meselson
Meselson, M. Explorations in the land of DNA and beyond.
Meselson (2003) Oocyte nuclear DNA content and GC proportion in rotifers of the anciently asexsual Class Bdelloidea.
Measurements of the genome size of the monogonont rotifer Brachionus plicatilis and of the bdelloid rotifers Philodina roseola and Habrotrocha constricta.
www.mcb.harvard.edu /Faculty/Meselson.html   (878 words)

  
 Undermining Terrorism : Speakers : Matthew S. Meselson
Matthew Stanley Meselson is the Thomas Dudley Cabot Professor of the Natural Sciences and a member of the BCSIA Board of Directors.
Meselson is a member of the National Academy of Sciences, the American Academy of Arts and Sciences, the American Philosophical Society, the Academie des Sciences (Paris), the Academia Sanctae Clarae (Genoa), the Royal Society (London), the Institute of Medicine, and the Council on Foreign Relations.
Meselson is presently a member of the Committee on International Security and Arms Control of the U.S. National Academy of Sciences.
www.ksg.harvard.edu /terrorism/people/meselson_matthew.html   (268 words)

  
 Harvard Sussex Program -- Matthew Meselson   (Site not responding. Last check: 2007-10-20)
Matthew Meselson, Thomas Dudley Cabot Professor of the Natural Sciences at Harvard University, teaches and conducts research in the Department of Molecular and Cellular Biology, and is also Faculty Chair for CBW Studies at the Belfer Center for Science and International Affairs.
Since 1963, Meselson has had an interest in chemical and biological defense and arms control and has served as a consultant on these subjects to various government agencies.
Meselson has served on the Council of the National Academy of Sciences and the Council of the Smithsonian Institution.
www.fas.harvard.edu /~hsp/matt.html   (272 words)

  
 Anthrax expert Matthew Meselson speaks out
In 1992-93, Harvard Professor Matthew Meselson investigated the largest known outbreak of inhalation anthrax in history, which occurred in the Soviet Union in 1979.
Meselson and his co-researchers documented the deaths of 66 people, and found 11 who survived.
In the wake of cases of anthrax being sent through the mail in 2001, Meselson addressed what information being released through the news media was accurate and what should be questioned.
www.researchmatters.harvard.edu /story.php?article_id=330   (248 words)

  
 "An Evolutionary Scandal"
Meselson and Mark Welch studied four genes in four species of bdelloids.
Cabot professor of the natural sciences Matthew Meselson and David Mark Welch, Ph.D. '99, have found evidence that bdelloid rotifers, a class of multicelled animals, have survived for 50 million to 100 million years without sexual reproduction.
A different type of hypothesis to account for the predominance of sex, one that Meselson's laboratory is currently exploring, holds that sex somehow purges the genome of deleterious mutations.
www.harvardmagazine.com /on-line/1100113.html   (722 words)

  
 Why Meiosis?
The objective of Matthew Meselson’s research is to understand why, and why the loss of these processes usually leads to early extinction.
Meselson is a member of the U.S. National Academy of Sciences, the Institute of Medicine, the American Academy of Arts and Sciences, the American Philosophical Society, the Académie des Sciences, the Accademia Sanctae Clarae, the Royal Society, the Russian Academy of Sciences and the Council on Foreign Relations.
A MacArthur Foundation fellow, Meselson has served on the Council of the National Academy of Sciences, the Council of the Smithsonian Institution and the Arms Control and Non-Proliferation Advisory Board to the Secretary of State, and presently serves on the Committee on International Security and Arms Control of the U.S. National Academy of Sciences.
www.rockefeller.edu /lectures/050903.php   (391 words)

  
 Harvard Gazette: Anthrax expert Matthew Meselson speaks
Matthew Meselson: 'There are about a half dozen labs in the U.S. where people are licensed to work with disease-causing anthrax.' (Staff photo by Jon Chase)
Matthew Meselson, Thomas Dudley Cabot Professor of the Natural Sciences, has been raising his voice in opposition to biological and chemical weapons since 1963.
Meselson co-directs the Harvard Sussex Program on Chemical and Biological Weapons Armament and Arms Limitation, an organization that has drafted a new international treaty on the production and use of such weapons.
www.news.harvard.edu /gazette/2001/11.08/01-meselson.html   (1246 words)

  
 Battling Bioterrorism  -  Harvard Magazine (January-February 2002)
The fact that a nearby military-research facility was the source of the aerosolized spores was rumored but not proven until the 1990s, when Guillemin and a team led by her husband, Cabot professor of the natural sciences Matthew Meselson, gathered enough information about the incident to document its epidemiology.
Biologist Matthew Meselson, encountering unaccustomed interest in his expertise on anthrax, advocated public-health measures and basic research to combat terrorism.
Meselson urged a three-pronged public-health response to the threat of biological weapons: prevention, shielding, and treatment.
www.harvard-magazine.com /on-line/010222.html   (678 words)

  
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David Mark Welch and Matthew Meselson reported a test of the bdelloid rotifers that suggests asexual evolution.
So, David Mark Welch and Matthew Meselson from Harvard university were using DNA sequence analysis and chromosome mapping to test this supposition.
Meselson found these asexual characteristics in the four bdelloid genes that he studied.
www.whozoo.org /Intro2001/Explorations/MJS_bdelloids.doc   (846 words)

  
 The Harvard Crimson :: News :: The Presidency: Clip and Save Part II
Meselson, who began his career as a research fellow at Cal Tech, has long been associated with the government's development of chemical and biological warfare.
Diplomacy comes into light because Meselson must work closely with the very people he is trying to undo in Washington; that he has accomplished as much as he has in limiting chemical and biological warfare is something of a miracle.
At present, Meselson is conducting a study of nerve gas for the American Association of University Professors.
www.thecrimson.com /printerfriendly.aspx?ref=354478   (2085 words)

  
 TIME.com: Abuzz over Bees -- Jun. 13, 1983 -- Page 1
Meselson, an authority on chemical weaponry, based his hypothesis on studies of tiny samples of yellow rain collected in Southeast Asia.
Meselson admits, however, that the origin of the toxins is not easily explained, though he noted that the poison might be produced by fungi that often grow on bee excrement.
In any case, Meselson says, the bee theory "opens up the realm of natural explanations for yellow rain in a way not previously done." The problem for the Government was that with international relations at stake, there was still so much room for scientific controversy.
www.time.com /time/magazine/article/0,9171,952023,00.html   (576 words)

  
 MBL :: Inside the MBL :: News :: Publications / Databases
Meselson received a $25,000 honorarium and a statuette of the Winged Victory of Samothrace at an awards ceremony held on October 1, in New York City.
In the years that followed, Meselson and Stahl carried out what is now known in the scientific world as the Meselson-Stahl experiment; in 1958 they showed that DNA duplication produces two identical daughter molecules, each containing one parent and one newly formed strand.
Meselson currently co-directs the Harvard Sussex Program, a collaborative effort between Harvard University and the University of Sussex, which promotes communication and training in support of informed public policy regarding chemical and biological warfare.
www.mbl.edu /inside/what/news/publications/labnotes/2004/04_fall03.html   (874 words)

  
 Matthew Meselson - Wikipedia, the free encyclopedia
He also demonstrated the enzymatic basis of a process by which cells recognize and destroy foreign DNA, and discovered methyl-directed mismatch repair, which enables cells to repair mistakes in DNA.
In 1963 Meselson served as a resident consultant in the US Arms Control and Disarmament Agency, since then he has been involved in chemical and biological weapons disarmament policy formation as a consultant and through the Harvard Sussex Program, a disarmament think-tank.
In 1992-94, he investigated and reported on the Sverdlovsk anthrax leak, a 1979 bio-warfare mishap in the Soviet Union that resulted in the deaths of 64 persons.
en.wikipedia.org /wiki/Matthew_Meselson   (423 words)

  
 Anthrax at Sverdlovsk, 1979
Meselson's doubts were increased by the account given by an American professor, fluent in Russian, who was living in Sverdlovsk at the time on a fellowship, who reported he had not seen anything extraordinary happen there in April 1979.
For Meselson, the fact that the U.S. accusations regarding the "yellow rain" toxins were eventually found to be unsubstantiated (in part through investigations with which Meselson was associated) likely only bolstered his doubts about the anthrax hypothesis coming from the same intelligence agencies.
Meselson was doubtful about the thoroughness of a 1980 U.S. study on the incident, but also felt the Soviets had not provided a satisfactory explanation, either.
www.gwu.edu /~nsarchiv/NSAEBB/NSAEBB61   (5592 words)

  
 A half DNA ladder is a template for copying the whole.
While Meselson and Stahl were doing their experiments, I was isolating the enzyme that synthesizes DNA, called DNA polymerase.
Matt Meselson and Frank Stahl in Oregon on a walk in the Cascade Mountains, 1984.
Matt Meselson is a Professor in the Department of Molecular and Cellular Biology at Harvard University.
www.dnaftb.org /dnaftb/text/20/index.html   (2929 words)

  
 ASA Newsletter - Article 01-6a
Meselson that we reprint this article with an update from him to precede the reprint.
Meselson described the size and source of a plume of anthrax spores in Sverdlosk in 1979.
Meselson has been at Harvard long enough to be classified a true New Englander and this evening his true New England spirit was tested to the max.
www.asanltr.com /newsletter/01-6/articles/016a.htm   (1776 words)

  
 Classics: Meselson and Stahl: The art of DNA replication -- Davis 101 (52): 17895 -- Proceedings of the National ...
Matthew Meselson and Franklin Stahl's experiments on the replication
Meselson and Stahl's experiment on the pages of many a syllabus.
a professor at the University of Oregon (Eugene, OR), and Meselson
www.pnas.org /cgi/content/full/101/52/17895   (1069 words)

  
 HSP-Matt
He is Chair of CBW Studies and a member of the Board of Directors of the Belfer Center for Science and International affairs at the Kennedy School of Government at Harvard.
Meselson has served on the Council of the National Academy of Sciences, the Council of the Smithsonian Institution, and the Arms Control and Nonproliferation Advisory Board of the US Secretary of State.
He is presently a member of the Committee on International Security and Arms Control of the US National Academy of Sciences and of the Editorial Board of the American Scholar.
www.sussex.ac.uk /Units/spru/hsp/matt.html   (272 words)

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