Maximum lifespan - Factbites

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Topic: Maximum lifespan

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	Longevity Report 91
		As a measure of lifespan extension I have used both the mean average and maximum lifespan of the experimental animals (or cohort), relative to the controls, known as the cohort mean and maximum lifespan, respectively.
		Cohort maximum lifespans — if measured by the age of the last survivor - are subject to high random scatter or uncertainty, since only one animal defines the maximum age from a relatively small group.
		A species maximum lifespan is typically defined against a reference population of millions of animals, whereas the number in the experimental cohort only defines the cohort lifespan.
	mcp.longevity-report.com

	Cellular aging (the Hayflick limit) and species longevity: a unification model based on clonal succession.
		In particular, it links the PDLs (population doubling limit) observed for various species to their mean lifespan; it explains the slow decline in PDL as a function of age of the donor; it establishes a thermodynamically stable maximum lifespan for a disease-free population; and it can explain why tissue transplants outlive donors or hosts.
		A model is presented which proposes a specific cause-and-effect relationship between a limited cell division potential and the maximum lifespan of humans and other mammals.
		In this model, the cells of these beds are proposed to exist in an ordered hierarchy which establishes a specific sequence for cell divisions throughout the organism's lifespan.
	www.arclab.org /medlineupdates/abstract_3600044.html (272 words)

	SIGNAMAX - 10/100 Managed Fiber Converters
		Equipped with Link Fault Signaling (LFS) and Loopback Testing capabilities, they extend the enterprise LAN configuration range up to 60 km while simultaneously minimizing downtime expense and extending the lifespan and reach of existing copper-based managed switches.
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	www.signamax.cz /index.php?typ=SXA&showid=107 (395 words)

	The free radical theory of aging
		The goal of all research on the free radical theory is to slow aging and increase maximum lifespan.
		One main problem with the free radical theory is the failure of antioxidants administered as dietary supplements, like vitamins E and C, to significantly increase maximum lifespan.
		By eliminating free radicals from cells through genetic means and dietary restriction, laboratories have extended the maximum age of laboratory animals.
	www.physics.ohio-state.edu /~wilkins/writing/Samples/shortmed/nelson/radicals.html (732 words)

	Longevity Report 91
		As a measure of lifespan extension I have used both the mean average and maximum lifespan of the experimental animals (or cohort), relative to the controls, known as the cohort mean and maximum lifespan, respectively.
		Cancer mortality rate rises, with time, as a quintic, approximately, from age 20 years, suggesting that the mutation rate is constant or rises slowly throughout adult life and that cancers are the result of, on average, 5 independent mutations.
		Chromium’s anti-glycation, glucose-regulatory action is mediated entirely via the protein insulin (a hormone); chromium, therefore, is a proteonomic cofactor with a single target protein, unlike the enzymic cofactors, which, typically, operate in conjunction with number of target enzymes.
	mcp.longevity-report.com (732 words)

	BBL - Longevity Records of North American Birds
		The maximum longevity record cannot be longer than the time span that researchers have been studying that species, and the lifespan of the bands used on birds was shorter than the lifespan of the birds for some species.
		While no bander goes out to study the maximum lifespan of a species as the only reason for their banding, every bander can contribute to this information.
		Records are constantly updated as new encounters are received by BBL and all records listed have been verified by BBL staff.
	www.pwrc.usgs.gov /bbl/homepage/longvrec.htm (732 words)

	Longevity Report 91
		A species maximum lifespan is typically defined against a reference population of millions of animals, whereas the number in the experimental cohort only defines the cohort lifespan.
		There are three fundamental problems with using species maximum lifespan as such a gerontological yardstick.
		Why not the select the phylum, order, class, genus, strain or even - as seems most likely - the individual
	mcp.longevity-report.com (732 words)

	Dinosaurs: Facts and Fiction
		Their possible maximum age can be estimated from the maximum lifespans of modern reptiles, such as the 66-year lifespan of the common alligator ( Alligator mississippiensis) and the impressive lifespan of a Black Seychelles Tortoise ( Geochelone (Aldabrachelys) sumeirei).
		One specimen of this now-extinct species, which was an adult when captured, lived a record 152 years in captivity (1766-1918) and had an accidental death.
	www.scienceviews.com /dinosaurs/dinofacts.html (732 words)

	Longevity Report 91
		Second, use of the species maximum lifespan assumes that aging is a constant across a species.
		In order of decreasing probability and increasing lifespan, we can expect dietary cofactor precursors to yield a mean average lifespan increase of at least:
		Primates, including humans and fruit bats, have lost the ability to synthesise ascorbic acid due to the high amounts in their fruit-rich diet.
	mcp.longevity-report.com (732 words)

	Idle Current Biasing - Why 70 percent?
		As long as the maximum plate dissipation for a tube is not exceeded at idle or under all signal levels from zero signal to maximum clip, it is operating in the "safe operating area" for that tube.
		It is important that the tube amp designers take it upon themselves to provide biasing and safe operating area information in the tech manual for the amplifier and insure that the design doesn't greatly exceed tube operating parameters if they want to insure a decent tube lifespan.
		The maximum average squarewave dissipation is around 24.8W, again within the safe operating area of the tube, and decreases to zero at full power squarewave output.
	www.aikenamps.com /Why70percent.html (732 words)

	Human Calorie Restriction: Frequently Asked Questions
		However as of this writing, there is no reliable evidence to support the notion that anything besides CR is capable of retarding biological aging or extending maximum lifespan in adult mammals.
		In a groundbreaking study, his team at UCLA were able to show that implementing CR gradually, with especial care to ensuring the nutritional adequacy of the animals&; diet, led to gains in lifespan in adult organisms proportionately similar to those observed in weanlings.
		By contrast, the goal of CR is slower aging and extended lifespan.
	www.cron-web.org /cronfaq.htm (1804 words)

	CAN YOU LIVE FOREVER?
		nd this book, HOW TO LIVE THE LONGEST LIFE POSSIBLE, is designed to help you to live to your Maximum Potential Lifespan, healthy, attractive, and youthful.
		So lifestyle practices are well established as major determinants of how long we can expect to live within our 120 year maximum, and also of the quality of that life.
		As of this writing, the longest lived person in the United Stated was Carrie White, who was born on November 18, 1874 and died on February 14, 1991 at the age of 116 years, 88 days.
	www.longestlife.com /forever.htm (1804 words)

	Free Radical Theory of Aging (hydrogen peroxide precursor)
		While mice with elevated catalase levels in the nucleus and cytoplasm experienced small increases in lifespan, animals that produced catalase in their mitochondria were found to experience a 20 percent increase in average and maximum lifespan and had healthier heart tissue.
		Hydrogen peroxide is produced during metabolism and is a precursor of free radicals that lead to cell damage, which causes the generation of even more free radicals.
		This adds credence to the theory that the mitochondria are a major source of free radicals generated as a byproduct of energy production.
	www.smartbodyz.com /Free-Radical-Theory-Aging-Hydrogen-Peroxide.htm (438 words)

	Talk:1 E9 s - Wikipedia, the free encyclopedia
		This says 120 years = estimated maximum human lifespan, but Jeanne Calment died at age 122.
		One could increase the 'estimate' to 125 years, or cite the lifespan of Jeanne Calment, which would be more precise.
		This page was last modified 06:22, 22 January 2006.
	en.wikipedia.org /wiki/Talk:1_E9_s (88 words)

	Scientific American: Lifespan
		Life span is defined as the observed age at death of an individual; maximum lifespan is the highest documented age at death for a species.
		Although such an extreme age at death is exceedingly rare, the maximum life span of humans has continued to increase because world records for longevity can move in only one direction: higher.
		From time to time we are told of a new highest documented age at death, as in the celebrated case of Madame Jeanne Calment of France who died at the age of 122.
	www.sciam.com /print_version.cfm?articleID=00079189-31B6-1CE5-93F6809EC5880000 (255 words)

	THE CRAN ARCHIVES -- MARCH 1998
		I think many of those practicing CRAN do so with their main focus on MAXIMUM lifespan rather than MEAN lifespan, but I am more convinced that the benefits of the latter rather than the former will follow from CRAN.
		It may be of interest that a sharp battle has just been fought in the UK with victory for those who have a different scientific interpretation of the data and, presumably, victory also for the meat interests.
		Practicing CRAN means that my appetite is usually pretty sharp, and I don't need to be making efforts to make things taste better.
	www.benbest.com /CRAN/cran_9803.html (14350 words)

	Praise to the forgotten blackcurrant
		The antioxidants found in blackcurrants also play an important role in helping to slow down the ageing process - they may not increase lifespan, but they can increase the chances of living to the maximum lifespan.
		While the Welsh-grown blackcurrant is no longer commonly used in foods, health experts say the "forgotten fruit" it is even healthier than the highly-praised blueberry, offering almost four times the vitamin C found in oranges and a wealth of health-promoting antioxidants that fight everything from flu and cold sores to cancer and heart disease.
		The health-giving properties of blackcurrants are mainly due to the fruit's high source of anthocyanins - the dark colour of blackcurrants reflects its high anthocyanin content - which can guard against flu and cold sore viruses.
	www.newstarget.com /009526.html (488 words)

	1963 CHEVROLET CORVAIR PICKUP
		It is also tested for ozone humidity fading and lightfastness for maximum lifespan, adding resale value to your CHEVROLET CORVAIR PICKUP.
		For maximum comfort it may also be can be rubber latex or polyethylene backed as an option, providing extra heat insulation and reducing road noise at the same time.
		Your new CORVAIR PICKUP replacement carpet is an excellent reproduction of the carpets used in most domestic vehicles from the 1950s through 1973.
	www.autocarpetonline.com /CHEVROLET_CORVAIR_PICKUP_1963_CARPET__2600-3573.html (508 words)

	Longevity Report 91
		The dosage extrapolations are from the amounts that have had either extended lifespan or, in the absence of definitive lifespan data, had the maximum physiological effects on animals (where possible, humans).
		, independently of cell division; reducing and combating cellular stress, by maintaining adequate coenzyme levels, will not only slow the rate of cell division (through lowering the requirement for damaged tissue repair and proliferation) but may actually extend the number of cell divisions permitted before the Hayflick limit is reached.
		Livers subjected to the stress of long-term chronic hepatitis or cirrhosis exhibit accelerated telomere shortening
	mcp.longevity-report.com (508 words)

	EN World - Morrus' D&D / d20 News & Reviews Site - The Haruspex [15 level and 10 level (new)]
		The haruspex' lifespan is equal to the maximum age for her race, plus the maximum die roll possible, all multiplied by 5.
		Haruspex - augur, goetia, seer, sibyl - the magus, medium, ovate, witch and warlock - a thousand names in a hundred languages for that mage who combines both druidic and arcane power into something more.
		If the haruspex and the target have a common language, she can generally force the target to perform as she desires within the limits of it's abilities.
	www.enworld.org /showthread.php?t=83850 (1784 words)

	Harbour Porpoise
		Those in western Greenlandic waters have a maximum life span of 15 years, whilst in British and Californian waters the lifespan is 24 years.
		The lifespan of the porpoises differs depending on where they are situated.
		Harbour porpoises are upper trophic level predators whose main food type differs with their locality.
	uk.geocities.com /l_jg/porpoise.html (129 words)

	Particle System
		Also, allowing a particle to be born with a negative lifespan seems kind of cruel, so I changed your check to be "if {$life <= 0} {set life 10}".
		All together, these variables include such things as total particles, yaw angle, pitch angle, number of particles emitted per frame, start and end colors, lifespan, speed, force factors, and a whole bunch of random inputs to impact all of the above.
		Currently, the GUI only exposes the maximum number of particles, wind, and gravity effects.
	wiki.tcl.tk /3252 (672 words)

	1973 BUICK APOLLO 2 DOOR CARPET
		It is also tested for ozone humidity fading and lightfastness for maximum lifespan, adding resale value to your BUICK APOLLO.
		For maximum comfort it may also be can be rubber latex or polyethylene backed as an option, providing extra heat insulation and reducing road noise at the same time.
		Your new APOLLO replacement carpet is an excellent reproduction of the carpets used in most domestic vehicles from the 1950s through 1973.
	www.autocarpetonline.com /BUICK_APOLLO_1973_CARPET__864-694.html (672 words)

	Calorie Restriction (CR) Mimetics: What is a CR Mimetic?
		Here we demonstrate that CR initiated in 19-month-old mice begins within 2 months to increase the mean time to death by 42% and increase mean and maximum lifespans by 4.7 (P = 0.000017) and 6.0 months (P = 0.000056), respectively.
		The efficacy of such compounds would, upon safe and successful testing in animal subjects, pave the way for substantial increases in human lifespan.
		This may, then, allow the organism to "eat normally" and enjoy a longevous lifespan.
	www.crmimetic.com (676 words)

	L-Carnosine Antiaging Miracle Alternative Health Supplement
		These experiments revealed that carnosine at a daily dose of 100 mg/kg of body weight was able to extend the mean lifespan of the mice by 20% but had no effect on the maximum lifespan.
		The brain membranes of animals treated with carnosine were characterized by a lower malonic dialdehyde (MDA) level, both initial (decreased by 35%) and that produced at 90 min of lipid peroxidation induced by ferric ions and ascorbic acid (by 30%) [10].
		Analysis of these data shows that carnosine acts as a true antioxidant protector rather than as an anabolic drug; the weight of the animals treated with carnosine was not significantly different from that of the control animals (table).
	www.ethosplan.com /antiaging.asp (1821 words)

	Longevity Report 91
		Cohort maximum lifespans � if measured by the age of the last survivor - are subject to high random scatter or uncertainty, since only one animal defines the maximum age from a relatively small group.
		Most longevity experiments on mammals are done on rodents (rats or mice); lifespan experiments on insects tend to be done on fruit flies.
		In each case, to qualify here as anti-aging, the life-extending cofactors have to have been tested against a control group of animals receiving a normal diet, comparable to our modern diet.
	www.cryonics-europe.org /lr/lr91.htm (1821 words)

	BioMarker Pharmaceuticals, Inc. Technology
		The ability of CR to retard aging and extend maximum lifespan in mammals was first clearly addressed by Dr. Clive McCay, a nutritionist at Cornell University in 1930's.
		Francis Peyton Rous showed that reducing food intake inhibited tumors in rodents.
		The history of caloric restriction research dates back to the 1910's.
	www.biomarkerinc.com /html/technology.htm (566 words)

	Brook Trout Salvelinus fontinalis
		Their relatively short lifespan (typically five years maximum) and slow growth rates contribute to their generally small size.
		Brook trout, along with lake trout, belong to the "char" sub-group of salmonine fishes that is distinct from the "true" trout and salmon.
		Aggregations of spawning brook trout can often be observed in small tributaries and along lake shorelines, with solitary females seen digging and remaining within the perimeter of shallow nests, and numerous males looking for an opportunity to dart into these nests to fertilize eggs deposited by the resident female.
	fish.dnr.cornell.edu /nyfish/Salmonidae/brooktrout.html (504 words)

	Common Kestrel
		On average, in the wild, a Kestrel will live for 18 months, around half dying in their first year and only just over 1/3rd surviving long enough to breed once, the maximum lifespan in the wild is around 10 years, which is very rare.
		The male Kestrel is distinguished from the female, by the grey colouration of the head.
		Kestrels "hover" facing into the wind, so they are moving through the air, but staying stationary with respect to the ground, this is called "wind-hovering".
	www.btinternet.com /~pauldfrost/kestrel.html (974 words)

	A proposed refinement of the mitochondrial free radical theory of aging
		A difficulty that has dogged the free radical hypothesis from early days is the very modest increase in maximum lifespan which results, in mammals, from antioxidant therapy(2).
		The peroxidation and polymerisation of the lipid molecules of the inner mitochondrial membrane by free radicals is substantially not repaired.
		His idea was that a major mechanism of aging might be the accumulation of damage to macromolecules, inflicted by free radicals (that is, molecules which carry an unpaired electron).
	www.oxygentimerelease.com /A/Therapies/Germanium/p5.htm (4019 words)

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In the News (Sun 27 Dec 09)