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Topic: Mean cell hemoglobin


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In the News (Sat 17 Aug 19)

  
  Complete blood count - Wikipedia, the free encyclopedia
The cells that circulate in the bloodstream are generally divided into three types: white blood cells (leukocytes), red blood cells (erythrocytes), and platelets or thrombocytes.
In the past, counting the cells in a patient's blood was performed manually, by viewing a slide prepared with a sample of the patient's blood under a microscope (a blood film, or peripheral smear).
Mean cell hemoglobin concentration (MCHC) - the average concentration of hemoglobin in the cells.
en.wikipedia.org /wiki/Blood_cell_count   (957 words)

  
 Mean cell hemoglobin concentration definition - Medical Dictionary definitions of popular medical terms
Mean cell hemoglobin concentration: The average concentration of hemoglobin in a given volume of blood.
The MCHC is a calculated value derived from the measurement of hemoglobin and the hematocrit.
(The hemoglobin value is the amount of hemoglobin in a volume of blood while the hematocrit is the ratio of the volume of red cells to the volume of whole blood.) The normal range for the MCHC is 32 - 36%.
www.medterms.com /script/main/art.asp?articlekey=9995   (221 words)

  
 Sickle Cell Review for clinicians
Sickle cell diseases are a group of inherited hemoglobin disorders characterized by chronic hemolytic anemia, a heightened susceptibility to infections, end-organ damage, and intermittent episodes of vascular occlusion causing both acute and chronic pain.
The factors that favor sickle cell formation include deoxygenation of the hemoglobin molecule, increased percentage of Hb S in the red blood cell, increased mean cell hemoglobin concentration which is a function of red cell hydration, low pH, and increased temperature, and blood stasis.
During sequestration episodes sickle cells are trapped in the spleen, causing rapid fall in the hemoglobin level and enlargement of the spleen.
www.scinfo.org /prod05.htm   (3163 words)

  
 University of Miami School of Medicine - Glossary - CBC
Hemoglobin is the protein molecule within red blood cells that carries oxygen and gives blood its red color.
Normal range for hemoglobin is different between the sexes and is approximately 13 - 18 grams per deciliter for men and 12 - 16 for women (international units 8.1 - 11.2 millimoles/liter for men, 7.4 - 9.9 for women).
This is a calculated volume derived from the hemoglobin measurement and the hematocrit.
www.med.miami.edu /glossary/art.asp?articlekey=9982   (420 words)

  
 Full blood count Article, Fullbloodcount Information   (Site not responding. Last check: 2007-11-02)
Mean cell volume (MCV) - the average volume of the red cells,measured in femtolitres.
Mean cell hemoglobinconcentration (MCHC) - the average concentration of hemoglobin in the cells.
Monocytes - This is raised in glandular fever.
www.anoca.org /cells/white/full_blood_count.html   (590 words)

  
 University of Miami School of Medicine - Glossary - Mean cell hemoglobin
Mean cell hemoglobin: The average amount of hemoglobin in the average red cell.
The mean cell hemoglobin (MCH) is a calculated value derived from the measurement of hemoglobin and the red cell count.
(The hemoglobin value is the amount of hemoglobin in a volume of blood while the red cell count is the number of red blood cells in a volume of blood.) The normal range for the MCH is 27 - 32 picograms.
www.med.miami.edu /glossary/art.asp?articlekey=9992   (106 words)

  
 NORMAL REFERENCE VALUES FOR HEMATOLOGICAL PARAMETERS,
The objective of this study was to determine the values of hematological parameters, red cell indices and Hb A2 and Hb F levels in normal Saudi children, living in the Central province of Saudi Arabia.
Hematological parameters, red cell indices, and hemoglobin types (Hb A2 and Hb F) were estimated, and the children were divided into 15 groups depending on the age.
Mean cell volume and mean cell hemoglobin also showed slight increases, while mean cell hemoglobin concentration remained more or less constant.
www.kfshrc.edu.sa /annals/213_214/01-035.htm   (667 words)

  
 Phenotypic Variability in Sickle Cell Disease
Fetal hemoglobin, as its name implies is the primary hemoglobin present in the fetus from mid to late gestation (Higgs et al, 1989).
These cells would be prone to sickling, and could occlude the microcirculation, blocking the flow of cells that normally might have made it across the circulatory narrows.
Reduction in overall hemoglobin concentration due to absent alpha genes is not the only mechanism by which alpha-thalassemia reduces the formation of dense and irreversibly sickled cells.
dwb.unl.edu /Teacher/NSF/C10/C10Links/sickle.bwh.harvard.edu/sickle_heterogeniety.html   (4610 words)

  
 Lab FAQ
It measures your white blood cells (WBC), red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), platelets (PLT), the size of the red cells (MCV), as well as the mean cell hemoglobin (MCH) and mean cell hemoglobin concentration (MCHC).
The hematocrit, mean cell hemoglobin, and mean cell hemoglobin concentration are various ways we measure your red cell count.
If your red blood cells or hemoglobin are very low, you may feel tired or become short of breath.
www.hoacny.com /html/lab_faq.html   (603 words)

  
 TKAS -- Lebelo et al. (2001)
White blood cell counts (WBCC) were determined by diluting the blood with Shaw's fluid (1:20) in a standard white blood cell pipette (Shaw, 1930) and the same procedure was followed as for the red blood cell count (Shaw, 1930; Hesser, 1960).
An additional explanation for the inability to show a significant change in packed cell volumes between the hypoxic group and healthy fish may have been the use of MS 222 as an anesthetic and heart puncture as a means for obtaining blood.
The effect of increased packed cell volume on apparent blood viscosity, as occurred in the disease group, was determined by comparing the apparent blood viscosity of the diseased group at its original mean packed cell volume of 40% to healthy striped bass at their mean packed cell volume of 30%.
www.emporia.edu /kas/trans104/lebelo/lebelo.htm   (4100 words)

  
 Information   (Site not responding. Last check: 2007-11-02)
Hemoglobin concentration is a more precise term than hemoglobin since the amount of hemoglobin per unit volume (L) is measured.
Hematocrit is measured by the direct reading of a blood-filled tube that has previously been centrifuged, or it is calculated from the hemoglobin by an electronic cell counting device.
The MCH classifies hypochromic (iron deficiency anemia, thalassemia) and normochromic (anemia of chronic disorders, anemia of renal disease).
www.aum.iawf.unibe.ch /HemoSurf/Demo_E/Info/PaRB.htm   (645 words)

  
 eMedicine - Macrocytosis : Article Excerpt by: Wendy Brick, MD
The amount of hemoglobin in the cell increases proportionately, so the mean cell hemoglobin concentration (MCHC) remains within normal limits.
Patients with hepatic disease and obstructive jaundice have a macrocytosis that is secondary to increased cholesterol and/or phospholipids deposited on the membranes of circulating RBCs.
The macrocytosis associated with COPD is attributed to excess cell water that is secondary to carbon dioxide retention.
www.emedicine.com /med/byname/macrocytosis.htm   (609 words)

  
 ipedia.com: Full blood count Article   (Site not responding. Last check: 2007-11-02)
However, with certain abnormal cells in the blood, they may be identified incorrectly, and not be as accurate as a manual count.
By multiplying the percentage, with the total number of white blood cells, an estimate of the absolute number of each type of white cell can be obtained.
Hemoglobin - The amount of hemoglobin in the blood, expressed in grams per liter.
www.ipedia.com /full_blood_count.html   (637 words)

  
 Diagnose-Me: Condition: A High White Count
The white blood cell count is done routinely as part of a complete blood count and further studies are usually needed if abnormalities are discovered through this test.
However, a low white blood cell count will make an individual susceptible to infectious diseases or allow multiplication of organisms within the body which are normally kept in check by the immune system.
White blood cells are composed primarily of neutrophils, monocytes and lymphocytes.
www.diagnose-me.com /cond/C276368.html   (649 words)

  
 Phenotypic Variability in Sickle Cell Disease
People with sickle cell trait would have a better chance of surviving an outbreak of malaria and passing their genes (for sickle and normal hemoglobin) to the next generation when they have children.
In contrast, splenomegaly is common in patients with sickle cell disease in India, while the spleens of most patients in the Americas are small and poorly functional (due to recurrent splenic infarctions).
Sickle cell disease in India exists mainly in the tribal populations, who to this day remain relatively isolated from the country's mainstream society.
sickle.bwh.harvard.edu /sickle_heterogeniety.html   (5261 words)

  
 Repertoire Magazine (An MDSI Publication)
In addition, a CBC may include a red cell distribution width (RDW), mean platelet volume (MPV) and a differential exam of the quality and quantity of white blood cells, notes the ASCLS.
While simply counting cells doesn’t fully describe their quality, these tests are more descriptive of the red blood cell population.
For instance, an MCV of 90 could signify that all of the patient’s cells are 90 femtoliters in volume, or it could suggest a range between 85 and 95.
www.medicaldistribution.com /repnew/viewarticle.asp?articleno=1630&issueid=131   (730 words)

  
 ASCLS - Laboratory Testing - Hematology Tests
Hemoglobin is a large complex protein made up of globin chains and heme found inside the red cells.
When looking at red cells, it is the hemoglobin that gives the cell its red color so less than adequate hemoglobin is known as hypochromia.
Cells whose granules stain bright red orange are called eosinophils and are part of the allergic response.
www.ascls.org /labtesting/labcbc.asp   (3437 words)

  
 Norwich Hep C page   (Site not responding. Last check: 2007-11-02)
HEMOGLOBIN (HGB) Hemoglobin is the main transport of oxygen and carbon dioxide in the blood.
Due to its use of red blood cells in its calculation, MCH is not as accurate as MCHC in its diagnosis of severe anemias.
W.B.C. (White Blood Cell Count) The white blood cell's main function is to fight infection, defend the body by phagocytosis against invasion by foreign organisms, and to produce, or at least transport and distribute, antibodies in the immune response.
www.norwich-hepc.org.uk /bloodpanel.html   (4799 words)

  
 morphology
Nucleated Erythrocytes: Nucleated red blood cells are commonly observed in regenerative anemias, but may also be observed in non-anemic or non-regenerative anemic states such as lead poisoning, hypoxia, or myeloproliferative disease in cats.
A target cell and a folded cell are seen in the center.
Leptyctes have a cell membrane that is thin and flimsy.
www.vetmed.auburn.edu /distance/clinpath/morphol   (1421 words)

  
 The District of Columbia Academy of Veterinary Medicine
The hemoglobin concentration is probably the most accurate (and the red cell count the least accurate) of the three analytes needed to calculate the red cell indices.
That is to say, the hemoglobin multiplied by 3 should approximate the hematocrit or the hematocrit divided by 3 should approximate the hemoglobin.
For example a buffy coat that is 3% of the microhematocrit tube represents a 50,000 white blood cell count/µl, 10,000 cells from the first percent and 20,000 cells for each of the remaining two percents.
www.dcavm.org /02nov.htm   (6019 words)

  
 Hemathology Unit - Laboratory 1 -  Pathology 6000 Laboratory - Department of Pathology - UCHSC   (Site not responding. Last check: 2007-11-02)
Scatter-plot B plots the size determination (the same as in scatter-plot A) on the y-axis against another side scatter determination (“lobularity”) on the x-axis as a means of differentiating the various white cell populations.
Use the scatter plot on the right side to determine where normal peripheral white blood cells are on scatter-plot A on the screen and on your print-out.
Figure 3 shows where normal peripheral white blood cells are on scatter-plot A. For interest’s sake, it also shows where they are on scatter-plot B. Note that the absolute counts for the white blood cells on the screen are fled out.
www.uchsc.edu /pathology/6000/hemlab1.htm   (1092 words)

  
 July 2004 Queries and Comments - College of American Pathologists   (Site not responding. Last check: 2007-11-02)
One hospital spins a hematocrit and then manually replaces all hemoglobin parameters, such as hemoglobin, mean corpuscular hemoglobin, and mean corpuscular hemoglobin count, with asterisks so those results are unavailable.
Lipemia interferes with the accurate determination of hemoglobin, or Hb, by spectroscopy on most hematology analyzers, but it does not generally interfere with determinations (especially impedance based) of red blood cell count, white blood cell count, and platelet count.
Since hematology analyzers measure mean cell volume, RBC, and Hb, and determine hematocrit, mean cell hemoglobin, and mean cell hemoglobin concentration, an inaccurate Hb affects the hematology result and those derived from it.
www.cap.org /apps/docs/cap_today/q_and_a/qa_07_04.html   (1257 words)

  
 Sulfentrazone (122836-35-5). Adverse Effects. Fluoride Action Network Pesticide Project.
The microcytosis may have arisen from the inhibition of heme synthesis as indicated by the presence of brown to yellow/brown pigmentation in hepatocytes and reticuloendothelial cells of the liver.
hemoglobin, hematocrit, mean cell volume, and mean cell hemoglobin.
during first 5 weeks of study; decreased hemoglobin, hematocrit, mean cell volume, mean cell hemoglobin and mean cell hemoglobin concentration, and increased absolute liver weights and alkaline phosphatase levels, and microscopic changes in the liver and spleen (pigmented sinusoidal microphages in the liver, swollen centrilobular hepatocytes and pigmented reticuloendotheli al cells in the spleen)
www.fluoridealert.org /pesticides/epage.sulfentrazone.htm   (2721 words)

  
 Laboratory Evaluation of Anemia
Hemoglobin (gm/dl) 13.5 - 17.5 11.5 - 15.5
Mean Cell Volum (MCV) (fl) 80.0 - 95.0
The cytomatic classification of the red blood cells will give us very important information for the first step in diagnosing the type of anemia we are investigating.
www.pitt.edu /AFShome/m/a/mazst19/public/html/leoa.html   (320 words)

  
 Journal of Perinatal & Neonatal Nursing: The complete blood count: physiologic basis and clinical usage.(Hematologic ...   (Site not responding. Last check: 2007-11-02)
The complete blood count is one of the most frequently ordered laboratory tests in medicine.
The components are the red blood cell count, hemoglobin, hematocrit, red blood cell indices (including the mean cell volume, mean cell hemoglobin, mean cell hemoglobin concentration, and red cell distribution width), reticulocyte count, white blood cell count and differential, and platelet count.
To aid in understanding the multiple uses of the complete blood count, the article discusses the function, life cycle, and physiology of the various cell components.
www.highbeam.com /library/doc0.asp?DOCID=1P1:29090308&refid=ip_encyclopedia_hf   (241 words)

  
 List of medical abbreviations - Wikipedia, the free encyclopedia
ASGUS Atypical squamous glandular cells of undetermined significance
The following are considered dangerous, non-standard abbreviations because their meanings could be easily misunderstood.
The Latin origin of the abbreviations is given in italics.
en.wikipedia.org /wiki/List_of_medical_abbreviations   (234 words)

  
 Chapter 1   (Site not responding. Last check: 2007-11-02)
percentage of red blood cells in whole blood.
*Mean Cell Hemoglobin and Mean Cell Hemoglobin Concentration -
essential component of enzymes concerned in hemoglobin synthesis and bone formation.
faculty.dbcc.cc.fl.us /thomasn/chapter_1.htm   (329 words)

  
 eMedicine - Macrocytosis : Article by Wendy Brick, MD
In acute or severe anemia, the volume of hemoglobin in the blood is inadequate to provide appropriate oxygenation of the tissues.
Macrocytosis in patients with COPD is attributed to excess cell water secondary to carbon dioxide retention.
Nucleated RBCs, teardrop cells, decreased and/or large platelets, and immature WBCs are often present in myelophthisic disease and leukemias.
www.emedicine.com /med/topic1381.htm   (2771 words)

  
 Diagnose-Me: Complete Blood Count
A set of measurements that are generally determined by specially designed machines that analyze the different components of blood in less than a minute.
Normal range varies slightly between laboratories but is generally between 4,300 and 10,800 cells per cubic millimeter.
Normal range for hemoglobin is different between the sexes and is approximately 13 - 18 gm/dl for men and 12 - 16 for women (international units 8.1 - 11.2 millimoles/liter for men, 7.4 - 9.9 for women).
www.diagnose-me.com /glossary/G1492.html   (674 words)

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