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Topic: Mefenamic acid

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	Mefenamic acid Information on Healthline
		Mefenamic acid is used to reduce pain caused by various conditions including menstruation.
		Mefenamic acid is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby.
		Mefenamic acid should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart.
	www.healthline.com /multumcontent/mefenamic-acid (797 words)

	Spherical Agglomeration of Mefenamic Acid and Nabumetone to Improve Micromeritics and Solubility: A Technical Note
		Mefenamic acid (2.5 g) was dissolved in 40 mL dimethylformamide (DMF) by gentle warming and the solution was added with stirring to 400 mL distilled water contained in the agglomerating vessel.
		Mefenamic acid (2.5 g) was dissolved in 40 mL DMF by gentle warming and then cooled to 25ºC. A solution of 0.1% wt/vol of hydroxypropylmethyl cellulose (HPMC) in distilled water (30 mL) was then added to it with stirring.
		Mefenamic acid in the aliquot was assayed spectrophotometrically at 285 nm.
	www.aapspharmscitech.org /view.asp?art=pt070248 (1780 words)

	Mefenamic acid - Wikipedia, the free encyclopedia
		Mefenamic acid is a non-steroidal anti-inflammatory drug used to treat pain, including menstrual pain.
		Mefenamic acid decreases inflammation (swelling) and uterine contractions by a still unknown mechanism.
		Mefenamic acid is known to cause an upset stomach, therefore it is recommended to take prescribed doses together with food or milk.
	en.wikipedia.org /wiki/Mefenamic_acid (302 words)

	Mefenamic (UK PID)
		Mefenamic acid was used as a tocolytic in a double blinded randomised human study.
		Constriction of the ductus arteriosus in utero is a pharmacological consequence arising from the use of prostaglandin synthesis inhibitors during pregnancy, as is inhibition of labour, prolongation of pregnancy, and suppression of renal function.
		The averages of mean daily concentrations of mefenamic acid in maternal plasma and milk were 0.94 microg/ml and 0.17microg/ml, respectively, corresponding to a milk:plasma ration of 0.18.
	www.intox.org /databank/documents/pharm/mefena/ukpid07.htm (1915 words)

	Mefenamic Acid Indications (Site not responding. Last check: 2007-10-08)
		The analgesic efficacy of mefenamic acid is documented for inflammatory and non-inflammatory pain.
		Mefenamic acid is one of the drugs of choice for dysmenorrhea (alongside with fenamaten, ibuprofen and naproxen).
		Whether mefenamic acid should be used for other acute pain or fever is controversial as there are other better tolerated analgesics (e.g.
	www.infomed.org /100drugs/mefaind.html (170 words)

	Synthesis and analgesic activity of N-arylhydrazone derivatives of mefenamic acid
		The hydrazide derivative of mefenamic acid (9) (Scheme 1) was prepared according to the previously described methods (7-8).
		All new N-arlyhydrazone derivatives of mefenamic acid (11-22) were initially evaluated for analgesic activity using the acetic acid induced mice abdominal constrictions test and the results are shown in Table 2.
		Since these 7 compounds showed more analgesic activity in comparison to mefenamic acid, we decided to evaluate their anti-inflammatory profile by using the carrageenan induced rat paw edema test and the results are summarized in Table 3.
	www.ualberta.ca /~csps/JPPS8(3)/A.Shafiee/mefenamic.htm (2212 words)

	Ponstan
		Mefenamic acid is used to relieve pain and inflammation in a wide range of musculoskeletal conditions, including rheumatoid arthritis, muscular pain and traumatic pain such as sprains, fractures and dislocations.
		Mefenamic acid should not be used in combination with painkilling doses of aspirin or any other NSAID taken by mouth, eg ibuprofen, as this increases the risk of side effects on the stomach and intestines.
		Mefenamic acid tablets, capsules and paediatric oral suspension are available without a brand name, ie as the generic medicine.
	www.netdoctor.co.uk /medicines/100002100.html (1522 words)

	Indomethacin Drug Information, Professional
		Fenoprofen, ibuprofen, indomethacin, mefenamic acid, and naproxen may also be taken prior to and during menstruation to prevent migraine associated with menstruation.
		Indomethacin is chemically related to the pyrroleacetic acid derivatives sulindac and tolmetin and to the pyranoindoleacetic acid derivative etodolac.
		This medication is chemically related to the indoleacetic acid derivative indomethacin and to the pyrroleacetic acid derivatives sulindac and tolmetin.
	www.drugs.com /MMX/Indomethacin.html (3922 words)

	Bioline International Official Site (site up-dated regularly)
		Maximum absorbance of the adduct was obtained at a Comparative analysis of two brands of mole fraction of 0.5 for the reagent solution mefenamic acid capsules by the official (Figure 5) and the absorbance was found to decrease at a lower or higher mole fractions.
		Comparative analysis of two brands of mefenamic acid capsules by the official titrimetric method and the new method is shown in Table 1.
		Diazo coupling of mefenamic acid with the reagent produced bathochromic shift in the absorption spectm of the reaction mixtures (Figure 2) relative to the absorption spectrum of mefenamic acid alone (Figure 1).
	www.bioline.org.br /request?pr02003 (2726 words)

	Mefenamic acid (Site not responding. Last check: 2007-10-08)
		Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs).
		Mefenamic acid binds the prostaglandin synthetase receptors COX-1 and COX-2, inhibiting the action of prostaglandin synthetase.
		Mefenamic acid is rapidly absorbed after oral administration.
	www.mongabay.com /health/medications/Mefenamic_acid.html (672 words)

	mefenamic acid
		Mefenamic acid passes into breast milk and may harm a nursing baby.
		Mefenamic acid may increase the sensitivity of your skin to sunlight.
		Mefenamic acid is available with a prescription under the brand name Ponstel.
	hw.healthdialog.com /kbase/multum/d00285a1.htm (1361 words)

	Drug Information: Mefenamic Acid (Print Version)
		If you experience any of the following symptoms, stop taking mefenamic acid and call your doctor: stomach pain, heartburn, vomiting a substance that is bloody or looks like coffee grounds, blood in the stool, or fl and tarry stools.Keep all appointments with your doctor and the laboratory.
		Mefenamic acid is used to relieve mild to moderate pain, including menstrual pain (pain that happens before or during a menstrual period).
		Mefenamic acid is in a class of medications called NSAIDs.
	www.nlm.nih.gov /medlineplus/print/druginfo/medmaster/a681028.html (970 words)

	Mefenamic Acid
		Mefenamic acid is a nonsteroidal anti-inflammatory and analgesic drug (trade name Ponstel) used to treat mild pain (especially menstrual cramps).
		Mefenamic acid is absorbed from the gastrointestinal tract.
		Mefenamic acid is extensively bound to plasma proteins.
	www.greatvistachemicals.com /pharmaceutical_intermediates/mefenamic_acid.html (190 words)

	ADCO-MEFENAMIC ACID 250 mg CAPSULES; ADCO-MEFENAMIC ACID 50 mg/5 mL SUSPENSION
		Mefenamic acid is used for the relief of mild to moderate pain in acute and chronic conditions including: pain of traumatic, arthritic or muscular origin; dysmenorrhoea; headache and dental pain.
		Mefenamic acid is used for the treatment of post traumatic conditions such as pain, swelling and inflammation, for a maximum period of five days.
		Mefenamic acid is contra-indicated in patients with peptic ulceration or having a history of gastro-intestinal bleeding and or inflammatory bowel disease.
	www.intekom.com /pharm/adcock/a-mefena.html (532 words)

	Ponstan mefenamic acid at discount prices from Canadian Online Pharmacy
		Ponstan (mefenamic acid) is used to relieve mild to moderate pain in patients 14 years of age and older for up to 7 days.
		Ponstan (mefenamic acid) should be used with extreme caution in patients with asthma, peptic ulceration, gastro-intestinal bleeding and recurrent episodes of diarrhea.
		Ponstan (mefenamic acid) is only to be used by the patient for whom it is prescribed.
	www.candrugstore.com /SiteMap/Ponstan_mefenamic_acid.htm (923 words)

	Medbroadcast Drug Info
		Mefenamic acid may prolong stomach bleeding caused by ASA.
		However, mefenamic acid itself appears to be less likely than ASA to cause stomach bleeding.
		Mefenamic acid should be taken under close medical supervision by people prone to irritation of the stomach and intestines, particularly those who have had a stomach ulcer, bloody stools, or diverticulosis or other inflammatory disease of the stomach or intestines (such as ulcerative colitis or Crohn's disease).
	www.medbroadcast.com /drug_info_details_pf.asp?brand_name_id=258 (1312 words)

	Treatment of menorrhagia during menstruation: randomised controlled trial of ethamsylate, mefenamic acid, and ...
		mefenamic acid and tranexamic acid was associated with a significant
		Fraser IS, Pearse C, Shearmann RP, Elliott PM, McIpveen J, Mokham R. Efficacy of mefenamic acid in patients with a complaint of menorrhagia.
		The effect of danazol, mefenamic acid, norethisterone and a progesterone impregnated coil on endometrial prostaglandin levels in women with menorrhagia.
	bmj.bmjjournals.com /cgi/content/full/313/7057/579 (3024 words)

	Mefenamic Acid - Drugs & Vitamins - Drug Library - DrugDigest
		Generic meclofenamate capsules are available, but generic mefenamic acid capsules are not yet available.
		It is especially important not to use meclofenamate or mefenamic acid during the last 3 months of pregnancy unless specifically directed to do so by your health care provider.
		Meclofenamate or mefenamic acid may cause problems in the unborn child or complications during delivery.
	www.drugdigest.org /DD/DVH/Uses/0,3915,413\|Mefenamic+Acid,00.html (991 words)

	Mefenamic Acid
		If you have an allergy to another nonsteroidal anti-inflammatory drug (NSAID), mefenamic acid, or any other part of the medicine.
		This medicine is used for the treatment of mild to moderate pain, inflammation, and fever; rheumatoid arthritis and osteoarthritis; and dysmenorrhea.
		Mefenamic acid reduces inflammation and pain by blocking production and release of chemicals that produce it.
	www.umm.edu /altmed/ConsDrugs/MefenamicAcidcd.html (540 words)

	SPIMACO Products
		Each Mafepain tablet contains 500mg mefenamic acid B.P. Action: Mafepain, mefenamic acid is a non-steroidal anti-inflammatory agent with analgesic and antipyretic effect.
		The diarrhoea has been investigated in some patients who have continued this drug in spite of its continued presence; these patients were found to have associated proctocolitis.
		In some cases reversible haemolytic anaemia has occurred with continuous administration of mefenamic acid for 12 months or longer.
	www.spimaco.com.sa /products/mafepain.html (459 words)

	Mefenamic Acid Drug Information
		Antirheumatic, nonsteroidal anti-inflammatory-Diclofenac; Diflunisal; Etodolac; Fenoprofen; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamate; Nabumetone; Naproxen; Oxaprozin; Phenylbutazone; Piroxicam; Sulindac; Tenoxicam; Tiaprofenic Acid; Tolmetin
		Studies in animals have not shown that fenoprofen, floctafenine, flurbiprofen, ibuprofen, ketoprofen, nabumetone, phenylbutazone, piroxicam, tiaprofenic acid, or tolmetin causes birth defects.
		This is especially important when you are taking indomethacin, mefenamic acid, phenylbutazone, or piroxicam, which should always be taken with food or an antacid.
	www.drugs.com /cons/Mefenamic_acid.html (7756 words)

	Salicylic acid - Wikipedia, the free encyclopedia
		This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone.
		Salicylic acid is toxic if ingested in large quantities, but in small quantities is used as a food preservative and antiseptic in toothpaste.
		Salicylates: Aspirin (Acetylsalicylic Acid), Diflunisal, Ethenzamide -- Arylalkanoic acids: Diclofenac, Indometacin, Sulindac
	en.wikipedia.org /wiki/Salicylate (566 words)

	Ponstel Online, Description, Chemistry, Ingredients - Mefenamic Acid - RxList Monographs
		(mefenamic acid) is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs).
		Each blue-banded, ivory capsule contains 250 mg of mefenamic acid for oral administration.
		Mefenamic acid is a white to greyish-white, odorless, microcrystalline powder with a melting point of 230
	www.rxlist.com /cgi/generic3/mefenamic.htm (259 words)

	Multiple IgA Autoantibodies Associated with Mefenamic Acid -- Gerbig et al. 129 (7): 588 -- Annals of Internal Medicine
		of treatment with mefenamic acid (0.5 to 1.0 g daily).
		acid therapy was stopped, and dapsone treatment was continued.
		Isaacs PE, Sladen GE, Filipe I. Mefenamic acid enteropathy.
	www.annals.org /cgi/content/full/129/7/588-a (421 words)

	Uses and side effects of Mefenamic Acid (via CobWeb/3.1 planetlab2.tamu.edu) (Site not responding. Last check: 2007-10-08)
		Mefenamic acid is used to treat pain and inflammation
		tell your doctor and pharmacist if you are allergic to mefenamic acid, aspirin or other medications for pain or arthritis, or any other drugs.
		Although side effects from mefenamic acid are not common, they can occur.
	arthritis-symptom.com.cob-web.org:8888 /arthritis-drugs/mefenamic-acid.htm (418 words)

	Healthopedia.com - Mefenamic Acid (Oral) (Ponstel) - Drugs Information, Side Effects, & Interactions
		You should not use this medicine if you have had an allergic reaction to mefenamic acid, aspirin, or other pain and arthritis medicines, such as Motrin®, Aleve® or Naprosyn®, Indocin®, or Clinoril®.
		Talk with your doctor before taking this medicine if you are pregnant, breastfeeding, or have heart disease, high blood pressure, liver or kidney disease, blood disorders, or ulcers or other stomach problems.
		You should not use mefenamic acid for more than 7 days unless your doctor tells you to.
	www.healthopedia.com /drugs/quick/mefenamic-acid (554 words)

	Consumer Reports Medical Guide - Mefenamic Acid
		NSAIDs such as mefenamic acid may cause ulcers, bleeding, or holes in the stomach or intestine.
		If you experience any of the following symptoms, stop taking mefenamic acid and call your doctor: stomach pain, heartburn, vomiting a substance that is bloody or looks like coffee grounds, blood in the stool, or fl and tarry stools.
		Be sure to tell your doctor how you are feeling so that your doctor can prescribe the right amount of medication to treat your condition with the lowest risk of serious side effects.
	www.consumerreports.org /mg/drug-reports/mefenamic-acid.htm (1247 words)

	Mefenamic Acid Shows Neuroprotective Effects and Improves Cognitive Impairment in in Vitro and in Vivo Alzheimer's ... (Site not responding. Last check: 2007-10-08)
		Mefenamic Acid Shows Neuroprotective Effects and Improves Cognitive Impairment in in Vitro and in Vivo Alzheimer's Disease Models -- Joo et al.
		Alzheimer's disease of mefenamic acid, a commonly used NSAID
		that mefenamic acid could be used as a therapeutic agent in
	molpharm.aspetjournals.org /cgi/content/abstract/69/1/76 (305 words)

	eMedicine - Toxicity, Nonsteroidal Anti-inflammatory Agents : Article by Neesha Suresh Desai, MD, MPH (Site not responding. Last check: 2007-10-08)
		Acetic acid derivatives - Diclofenac sodium (Voltaren), indomethacin (Indocin), sulindac (Clinoril), etodolac (Lodine), ketorolac (Toradol), nabumetone (Relafen), and tolmetin sodium (Tolectin)
		Lactic acid levels, as well as ketones, should be obtained in patients with acidosis.
		Consider admission for all significant ingestions of phenylbutazone, mefenamic acid, and meclofenamate, whether symptomatic or not.
	www.emedicine.com /emerg/topic341.htm (4002 words)

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