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Topic: Megaloblastic anemia

Related Topics

Schilling test

Anemia

Hemolysis

Malabsorption

Intrinsic factor

Red blood cell

Vitamin

Vitamin B12

Jaundice

Primary biliary cirrhosis

Spleen

Methotrexate

Bile

Xanthelasma

Skolem normal form

	Anemia - Wikipedia, the free encyclopedia
		In older patients, iron deficiency anemia is often due to bleeding lesions of the gastrointestinal tract; fecal occult blood testing, upper endoscopy and lower endoscopy are often performed to identify bleeding lesions, which can be malignant.
		Megaloblastic anemia due to a deficiency of either vitamin B12 or folic acid (or both) due either to inadequate intake or insufficient absorption.
		The cause of megaloblastic anemia is primarily a failure of DNA synthesis with preserved RNA synthesis, which result in restricted cell division of the progenitor cells.
	en.wikipedia.org /wiki/Anemia (2292 words)

	Diagnose-Me: Condition: Megaloblastic Anemia / Pernicious Anemia
		Megaloblastic anemias are somewhat rare blood disorders characterized by the presence of large, structurally and visually abnormal, immature red blood cells (megaloblasts).
		Megaloblastic anemias are usually caused by a deficiency or defective absorption of either vitamin B12 (cobalamin) or folic acid.
		Pernicious anemia usually does not appear before the age of 30, although a juvenile form of the disease can occur in children and is evident before the child is 3 years old.
	www.diagnose-me.com /cond/C364379.html (3587 words)

	OHSU Health - Megaloblastic (Pernicious) Anemia (Site not responding. Last check: 2007-10-29)
		Megaloblastic anemia, also called pernicious anemia, is a type of anemia characterized by very large red blood cells.
		Megaloblastic (pernicious) anemia results from a lack of intrinsic factor in gastric secretions (a substance needed to absorb vitamin B12 from the gastrointestinal tract).
		Megaloblastic (pernicious) anemia may also be associated with type 1 diabetes, thyroid disease, and a family history of the disease.
	www.ohsuhealth.com /htaz/blood/blooddis/anemia/megaloblastic_pernicious_anemia.cfm (349 words)

	Lancaster General Hospital - Megaloblastic (Pernicious) Anemia (Site not responding. Last check: 2007-10-29)
		Pernicious anemia is a type of megaloblastic anemia caused by an inability to absorb Vitamin B-12 due to a lack of intrinsic factor in gastric (stomach) secretions.
		Megaloblastic anemia may be suspected from general findings from a complete medical history and physical examination of your child.
		If the megaloblastic anemia is thought to be caused from a problem in the digestive tract, a barium study of the digestive system may be performed.
	www.lancastergeneral.org /content/greystone_22520.asp (461 words)

	Loyola Univ. Health Sys. - Blood Disorders - Megaloblastic (Pernicious) (Site not responding. Last check: 2007-10-29)
		Megaloblastic (pernicious) anemia is a rare disorder in which the body does not absorb enough vitamin B12 from the digestive tract, resulting in an inadequate amount of red blood cells (RBCs) produced.
		Anemia is a common blood disorder, which is caused when there is a drop in hemoglobin or hematocrit in the blood.
		Because anemia is often a symptom associated with another disease, it is important for your physician to be aware of symptoms you may be experiencing.
	www.luhs.org /health/topics/blood/aneper.htm (487 words)

	Megaloblastic anemia - Wikipedia, the free encyclopedia
		Megaloblastic anemia is anemia resulting from a deficiency of vitamin B12 and folic acid.
		Bone marrow (not normally checked in a patient suspected of megaloblastic anemia) shows megaloblastic hyperplasia.
		The Schilling test is often performed to determine the nature of the vitamin B12 deficiency.
	en.wikipedia.org /wiki/Megaloblastic_anemia (182 words)

	Frankford Hospitals - Megaloblastic (Pernicious) Anemia
		Megaloblastic anemia is a type of anemia characterized by very large red blood cells.
		Other types of megaloblastic anemia may be associated with type 1 diabetes, thyroid disease, and a family history of the disease.
		Megaloblastic anemia is usually discovered during a medical examination through a routine blood test.
	www.frankfordhospitals.org /healthinfo/adult/blood/aneper.html (459 words)

	s021002a - Megaloblastic Anemia
		Serum lactate dehydrogenase in diagnosis of megaloblastic anaemia.
		Six of the eight episodes of anemia were complicated by illnesses of an inflammatory or infectious nature, two patients had iron deficiency, two appeared to have a thalassemia trait, and one had severe renal failure.
		Abstract: The diagnosis of megaloblastic anemia and the differentiation of folate and vitamin B12 deficiency require, in addition to careful attention to the history and physical findings, the use of laboratory tests.
	www.emory.edu /WHSCL/grady/amreport/litsrch02/s021002a.html (1254 words)

	Understanding Anemia -- the Basics
		Anemia is a condition that develops when your blood is deficient in healthy red blood cells, which are the main transporter of oxygen to organs.
		Women in the childbearing years are particularly susceptible to a form of anemia called iron-deficiency anemia because of the blood loss from menstruation and the increased blood supply demands during pregnancy.
		Iron deficiency anemia occurs because of a lack of the mineral iron in the body.
	www.webmd.com /content/article/8/1680_54569.htm (1215 words)

	MedlinePlus Medical Encyclopedia: Megaloblastic anemia
		Megaloblastic anemia is a blood disorder characterized by anemia, with red blood cells that are larger than normal, usually resulting from a deficiency of folic acid or of vitamin B-12.
		Deficiencies of vitamin B-12 and folic acid are the most common causes of megaloblastic anemia.
		The objective of treatment is to determine the cause of the anemia, and the treatment depends upon the cause.
	www.nlm.nih.gov /medlineplus/ency/article/000567.htm (363 words)

	The Analyst - Internet Health Report: Condition: Anemia, Megaloblastic
		Megaloblastic anemia is a blood disorder characterized by red blood cells that are larger than normal resulting from certain nutritional deficiencies, absorption problems or other conditions.
		Decreased MCH is associated with microcytic anemia and increased MCH is associated with macrocytic anemia.
		Megaloblastic anemia is usually caused by a B12 deficiency, and only secondarily by a folic acid deficiency.
	www.digitalnaturopath.com /cond/C363969.html (4555 words)

	MedlinePlus Medical Encyclopedia: Anemia
		Anemia is a lower than normal number of red blood cells (erythrocytes) in the blood, usually measured by a decrease in the amount of hemoglobin.
		Anemia can be confirmed by a red blood count or hemoglobin level.
		Severe anemia can cause low oxygen levels in vital organs such as the heart and can lead to heart attack.
	www.nlm.nih.gov /medlineplus/ency/article/000560.htm (397 words)

	eMedicine - Megaloblastic Anemia : Article by Paul Schick, MD
		The development of megaloblastic anemia is usually insidious; therefore, patients are often relatively asymptomatic because they have had time to adjust to the marked fall in hemoglobin (Hgb) levels.
		Pernicious anemia: This is the best-known cause of cobalamin deficiency.
		In a typical clinical presentation of megaloblastic anemia, a low serum cobalamin level and a full response to cobalamin may be sufficient to establish a diagnosis.
	www.emedicine.com /MED/topic1420.htm (6580 words)

	Anemia (Site not responding. Last check: 2007-10-29)
		Anemia of chronic disease (ACD) is generally a condition that is triggered by a persistent inflammatory process that is, in turn, a by-product of the disease-fighting immune system.
		Maternal iron deficiency anemia is associated with increased weight or size of the placenta, a condition that may pose a risk for later high blood pressure in the offspring.
		People with pernicious anemia, which results in an inability to absorb the vitamin, are not only at risk for neurologic damage, but also have a higher risk for stomach cancer and possibly cancer of the throat and mouth.
	www.reutershealth.com /wellconnected/doc57.html (10022 words)

	eMedicine - Anemia, Megaloblastic : Article by James L Harper, MD (Site not responding. Last check: 2007-10-29)
		The megaloblastic effect is characterized by an aregenerative macrocytic anemia with nuclear dysmaturity, where the nucleus appears immature relative to the cytoplasm because of impaired DNA synthesis.
		Megaloblastic anemia is caused by deficiency of THF.
		Clinically, this is apparent as a resolution of megaloblastic anemia, with progressive dementia and long-tract neurologic deficits.
	www.emedicine.com /PED/topic2575.htm (3533 words)

	eMedicine - Pernicious Anemia : Article by Marcel E Conrad, MD
		Patients with pernicious anemia have a 2- to 3-fold increased incidence of gastric carcinoma.
		Anemia: The anemia often is well tolerated in pernicious anemia, and many patients are ambulatory with hematocrit levels in the mid teens.
		Outpatient follow-up of patients with pernicious anemia is required to ensure that they have responded to therapy with Cbl and that they continue to receive Cbl on a regular basis for the remainder of their life.
	www.emedicine.com /med/topic1799.htm (5747 words)

	Anemia, Megaloblastic
		An anemia is a condition in which the number of red blood cells (RBC) or the amount of hemoglobin (the protein in red blood cells that carries oxygen throughout the body) is below normal.
		Megaloblastic Anemias (MGA) are rare blood disorders characterized by the presence of large, structurally and visually abnormal, immature red blood cells (megaloblasts).
		In most cases, the fundamental flaws leading to the several forms of MGA caused by vitamin deficiencies are present at the time of birth and exist as a result of a genetic defect.
	www.webmd.com /hw/anemia/nord423.asp (476 words)

	Health Topic Library (Site not responding. Last check: 2007-10-29)
		Megaloblastic anemia is more common in individuals of northern European descent.
		The symptoms of megaloblastic anemia may resemble other blood conditions or medical problems.
		In addition to a complete medical history and physical examination, diagnostic procedures for megaloblastic anemia may include additional blood tests and other evaluation procedures, including the Schilling test.
	www.muschealth.com /health_info/health_atoz/atoz.htm?pageid=P00080 (378 words)

	Bioline International Official Site (site up-dated regularly)
		The biologic basis of elevated MPXI in patients with megaloblastic anemia is the presence of increased number of MPXI- laden granules in the neutrophils due to skipped cellular divisions during maturation.
		Fifty cases of megaloblastic (35 males and 15 females) and 46 patients with aplastic anemia (31 males and 15 females) met the study criteria.
		Differentiation of megaloblastic anemia from the other causes of macrocytosis requires the use of laboratory tests such as complete blood count, peripheral smear examination, and bone marrow specimen.
	www.bioline.org.br /request?ms04061 (1103 words)

	AccessMedicine - Harrison's Internal Medicine: Clinical Disorders
		In temperate zones, folate deficiency in alcoholics and cobalamin deficiency due to pernicious anemia or achlorhydria are the common types of megaloblastic anemias.
		In certain areas close to the equator, tropical sprue is endemic and an important cause of megaloblastic anemia, while in Scandinavia, infestations by the fish tapeworm, Diphyllobothrium latum, may be a cause.
		Cobalamin in food is tightly bound to enzymes in meat and is split from these enzymes by hydrochloric acid and pepsin in the stomach.
	www.accessmedicine.com /content.aspx?aID=64438 (272 words)

	Anemia Profile, Megaloblastic, Serum
		In the clinical assessment of patients with megaloblastic anemias, a cutoff of +3 SD provides greater specificity in the diagnosis of the vitamin deficiency states, despite the sacrifice of some sensitivity.
		The megaloblastic anemia profile monitors four compounds: methylmalonic acid, 2-methylcitric acid, homocysteine, and cystathionine.
		deficiency (megaloblastic anemia, cobalamin deficiency) and that homocysteine and cystathionine are elevated if there is a folic acid deficiency.
	www.labcorp.com /datasets/labcorp/html/chapter/mono/tx008700.htm (546 words)

	ENLmedical.com: Conditions And Concerns: Medical Encyclopedia: Megaloblastic anemia
		This picture shows large, dense, oversized, red blood cells (RBCs) that are seen in megaloblastic anemia.
		Megaloblastic anemia can occur when there is a deficiency of vitamin B-12.
		Glossitis: Glossitis is an inflammatory condition of the tongue which results in reddening, loss of papilla (giving the tongue a smooth glossy appearance), and irritation.
	www.enlmedical.com /article/000567.htm (227 words)

	Hematology and Blood Disorders - Megaloblastic Anemia
		There are many causes of megaloblastic anemia, but a cause in some children occurs from a vitamin deficiency of folic acid or vitamin B12.
		The deficiency of folic acid or vitamin B12 causing megaloblastic anemia may include the following:
		Megaloblastic anemia may be suspected from general findings from a medical history and physical examination of your child.
	www.chkd.org /Hematology/megalob.asp (643 words)

	Megaloblastic Anemia - otherhealth.com
		If you treated (or can treat) a person suffering from Megaloblastic Anemia - please describe anything that can be helpful to me, as I am trying to treat one person, but lack any experience.
		'Deficiencies or malabsorption of Vitamin B-12 and folic acid are the most common causes of megaloblastic anemia.
		If all of the above does not apply, and the cause is idiopathic, then you could consider using the larger anemia rubric and see if one of those remedies fits the constitutional picture.
	www.otherhealth.com /showthread.php?t=2545 (393 words)

	Megaloblastic (Pernicious) Anemia - My Child Has - Children's Hospital Boston
		Megaloblastic (Pernicious) Anemia - My Child Has - Children's Hospital Boston
		This Health Topic is not associated with any programs or procedures.
		What are the symptoms of megaloblastic (pernicious) anemia?
	www.childrenshospital.org /az/Site1287/mainpageS1287P0.html (472 words)

	Anemia, Megaloblastic
		It is possible that the main title of the report Anemia, Megaloblastic is not the name you expected.
		This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD).
		Healthwise disclaims any liability for the decisions you make based on this information.
	www.bchealthguide.org /kbase/nord/nord423.htm (435 words)

	MEGALOBLASTIC ANEMIA (Site not responding. Last check: 2007-10-29)
		2. distinguish the important morphologic features of the megaloblastic anemias
		3. diagnose pernicious anemia by use of the appropriate laboratory tests
		4. describe and explain the major clinical features of pernicious anemia and anemia of folic acid deficiency
	www.med.unr.edu /medlib/pathsyl/meganem.html (539 words)

	Hemic and Lymphatic Diseases
		A small set of FAQs answered by the Aplastic Anemia and MDS Int'l Foundation, Inc.
		The Fanconi Anemia Research Fund, including Fanconi Anemia Handbook [3rd ed., 2000 L and D Frohnmayer]
		About Haemolytic Anemia [P Schick] - emedicine Some brief notes about Anemia, Hemolytic - Jeffrey Hull's Prod.
	www.mic.ki.se /Diseases/C15.html (2117 words)

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