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Topic: Mesangial cell

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	Gene expression profiling reveals role for EGF-family ligands in mesangial cell proliferation -- Mishra et al. 283 ...
		of cells in trypsinized monolayers was quantified using a hemocytometer.
		An important challenge in renal cell biology is to understand gene regulatory pathways that control mesangial cell growth.
		Role of mesangial cell in glomerular response to volume and angiotensin II.
	ajprenal.physiology.org /cgi/content/full/283/5/F1151 (4264 words)

	A Protective Role for Kidney Apolipoprotein E. REGULATION OF MESANGIAL CELL PROLIFERATION AND MATRIX EXPANSION -- Chen ...
		Mesangial Cell Is a Source of ApoE in Kidney-- To correlate apoE expression to mesangial expansion, we determined apoE expression in kidney and kidney cell types.
		Confluent mesangial cells were incubated in medium containing 50 µg/ml OxLDL with or without 10 µg/ml apoE and incubated for 48 h.
		Cells were washed with PBS, and apoptotic cells were determined by using a modified TUNEL assay and examined under microscope.
	www.jbc.org /cgi/content/full/276/52/49142 (4229 words)

	Mesangial Cell Hypertrophy by High Glucose Is Mediated by Downregulation of the Tumor Suppressor PTEN -- Mahimainathan ...
		Mesangial Cell Hypertrophy by High Glucose Is Mediated by Downregulation of the Tumor Suppressor PTEN -- Mahimainathan et al.
		A: Serum-deprived mesangial cells were incubated with nonspecific IgG or TGF-ß antibody (5 µg/ml) for 1 h before incubation with glucose as described in Fig.
		D: Mesangial cells were infected with Smad7 adenovirus or green fluorescent protein adenovirus (moi 50) for 24 h before incubation with glucose as described in Fig.
	diabetes.diabetesjournals.org /cgi/content/full/55/7/2115 (5447 words)

	High glucose-enhanced activation of mesangial cell p38 MAPK by ET-1, ANG II, and platelet-derived growth factor -- ...
		Growth-arrested mesangial cells in 5.6 mM glucose were treated with 100 nM ET-1 for 10 min, 1 µM ANG II for 5 min, or 50 ng/ml PDGF for 10 min.
		Mesangial cells were growth arrested for 3 days in 5.6 (NG) or 30 mM (HG) glucose-containing media followed by acute stimulation with 10 nM ET-1 for 10 min, 100 nM ANG II for 5 min, or 5 ng/ml PDGF for 10 min.
		Mesangial cell apoptosis was examined using an in vitro cell death detection assay.
	ajpendo.physiology.org /cgi/content/full/282/1/E161 (5770 words)

	The Role of ADAM 15 in Glomerular Mesangial Cell Migration -- Martin et al. 277 (37): 33683 -- Journal of Biological ...
		Mesangial cells (MC) occupy the core of the renal glomerulus and are surrounded by a mesangial matrix.
		Human Mesangial Cell (HMC) Culture and Identification-- Human glomeruli were obtained by the serial sieving of normal human kidney cortex recovered at nephrectomy.
		A third method of studying cell migration was used in experiments to analyze the effect of antisense ADAM 15 oligonucleotides.
	www.jbc.org /cgi/content/full/277/37/33683 (5230 words)

	Hematopoietic origin of glomerular mesangial cells -- Masuya et al. 101 (6): 2215 -- Blood
		Mesangial cells constitute a population of cells residing in the glomerular mesangium between the capillary endothelial cells
		mesangial cells in the kidney of lethally irradiated mice.
		Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists.
	www.bloodjournal.org /cgi/content/full/101/6/2215 (3433 words)

	Interleukin-10 Is a Mesangial Cell Growth Factor In Vitro and In Vivo (Site not responding. Last check: 2007-10-09)
		As macrophages are known to produce interleukin-10 (IL-10), we investigated the effect of recombinant murine IL-10 (rIL-10) on mesangial cell growth.
		These cells exhibited a dose-dependent proliferative response to rIL-10 (23 % to 70 % at 80 ng/mL; p < 0.01), as assessed by both 3H thymidine uptake and cell count.
		Rat mesangial cells were also shown to express IL-10 mRNA and protein, as determined by Northern blotting and immunostaining, thereby suggesting a role for IL-10 in autocrine mesangial cell growth.
	info.med.yale.edu /labinvest/abstracts/97months/9705may/7653.html (393 words)

	Angiogenic Protein Cyr61 is Expressed by Podocytes in Anti-Thy-1 Glomerulonephritis -- Sawai et al. 14 (5): 1154 -- ...
		Inhibition of PDGF-Induced Mesangial Cell Migration by Supernatant of Cyr61-Overexpressing Cells
		Mesangial cells plated in modified Boyden chambers were incubated for 3 h with supernatant of Cyr61-transfected or mock-transfected COS-7 cells, which was supplemented with or without PDGF-BB.
		Mesangial cells were incubated with media containing supernatant of Cyr61-transfected or mock-transfected COS-7 cells, together with or without 10 ng/ml PDGF-BB.
	jasn.asnjournals.org /cgi/content/full/14/5/1154 (5068 words)

	Glucose Induces Clonal Selection and Reversible Dinucleotide Repeat Expansion in Mesangial Cells Isolated from ...
		Mesangial cells cultured in 6 mmol/l glucose were exposed to 25 mmol/l glucose for 35 days.
		Mesangial cell clones from ROP mice had either 20 or 24 d(CA) repeats.
		was observed in 20 of the 100 mesangial cell subclones (Fig.
	diabetes.diabetesjournals.org /cgi/content/full/52/10/2594 (5398 words)

	Acute glomerular upregulation of ornithine decarboxylase is not essential for mesangial cell proliferation and matrix ...
		with the onset of mesangial cell proliferation and growth-factor
		A significant decrease in mesangial matrix deposition was observed at 6 h due to anti-Thy1-antibody-induced mesangial cell lysis, while a significant increase in glomerular matrix expansion is observed on day 7 reflecting a characteristic feature in this model.
		Inhibition of immediate-early-gene induction in renal mesangial cells by depletion of intracellular polyamines.
	ndt.oxfordjournals.org /cgi/content/full/15/1/16 (3142 words)

	The Glomerulosclerosis of Aging in Females: Contribution of the Proinflammatory Mesangial Cell Phenotype to Macrophage ...
		Mesangial cells were isolated from TNFR1 and from TNFR2 knockout mice.
		The ratio of RANTES or VCAM-1 to GAPDH in mesangial cells lacking TNFR1 (R1) at baseline was arbitrarily defined as 100%.
		and expression of this mesangial cell phenotype in vivo and
	ajp.amjpathol.org /cgi/content/full/165/5/1789 (5142 words)

	Inhibition of Mesangial Cell Nitric Oxide in MRL/lpr Mice by Prostaglandin J2 and Proliferator Activation ...
		Inhibition of Mesangial Cell Nitric Oxide in MRL/lpr Mice by Prostaglandin J2 and Proliferator Activation Receptor-{gamma} Agonists -- Reilly et al.
		Cells were cultured for 1, 4, 8, or 24 h with LPS (1 µg/ml) and IFN-
		Nitric oxide: an inflammatory mediator of glomerular mesangial cells.
	www.jimmunol.org /cgi/content/full/164/3/1498 (4420 words)

	Pressure Oscillation Regulates Human Mesangial Cell Growth and Collagen Synthesis -- Mertens et al. 32 (5): 945 -- ... (Site not responding. Last check: 2007-10-09)
		Pressure Oscillation Regulates Human Mesangial Cell Growth and Collagen Synthesis -- Mertens et al.
		Cell cultures were grown under atmospheric pressure (AP)
		cell growth and collagen synthesis are influenced by hyperbaric
	hyper.ahajournals.org /cgi/content/abstract/32/5/945 (366 words)

	Transmembrane signalling in human monocyte/mesangial cell co-cultures: role of cytosolic Ca2+ -- Menè et al. 17 ...
		Intercellular adhesion molecules and vascular cell adhesion molecule-1 and the kidney.
		Chemoattractants provoke monocyte adhesion to human mesangial cells and mesangial cell injury.
		Menè P, Pugliese F, Cinotti GA. Regulation of capacitative calcium influx in cultured human mesangial cells: roles of protein kinase C and calmodulin.
	ndt.oxfordjournals.org /cgi/content/full/17/1/42 (4055 words)

	Effect of vitamin D and matrix metalloproteinases on mesangial cell phenotype
		Recent data suggests that 1,25-(OH)2D3 blocks dendritic cell maturation influencing the development of regulatory T cells.
		Further, we hypothesize that 1,25-(OH)2D3 may alter the balance of matrix deposition and removal in mesangial cells by altering MMP expression.
		Primary rat masangial cells will be isolated, placed in culture in the presence or absence of 1,25-(OH)2D3 and subjected to mechanical stretch (stress).
	www.surgery.wisc.edu /transplant/research/grant_dah_nkf.shtml (559 words)

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