| | CiteULike: Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in ... (Site not responding. Last check: 2007-10-30) |
 | | Classical tissue transplant experiments in the chick and recent studies in the mouse indicated that interactions with the cardiogenic mesoderm are necessary and sufficient to induce the liver in the ventral foregut endoderm. |
 | | Using molecular markers and functional assays, we now show that septum transversum mesenchyme cells, a distinct mesoderm cell type, are closely apposed to the ventral endoderm and contribute to hepatic induction. |
 | | Specifically, using a mouse Bmp4 null mutation and an inhibitor of BMPs, we find that BMP signaling from the septum transversum mesenchyme is necessary to induce liver genes in the endoderm and to exclude a pancreatic fate. |
| www.citeulike.org /user/Schmidtc/article/774412 (411 words) |