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Topic: Methcathinone

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Cathinone

Phenethylamines

Amphetamine

Catha edulis

Crystal meth

Methamphetamine

Ephedrine

Desoxyn

Methylphenidate

Salvia divinorum

Intravenous infusion

Stimulant

Pseudoephedrine

Substance abuse

Clandestine chemistry

	Methcathinone
		Methcathinone, known on the streets as "Cat," is a structural analogue of methamphetamine and cathinone.
		Clandestinely manufactured, methcathinone is almost exclusively sold in the stable and highly water soluble hydrochloride salt form.
		Methcathinone has an abuse potential equivalent to methamphetamine and produces amphetamine-like activity.
	www.streetdrugs.org /methcathinone.htm (79 words)

	Methcathinone - Wikipedia, the free encyclopedia
		Methcathinone hydrochloride increases spontaneous rodent locomotor activity, potentiates the release of dopamine from dopaminergic nerve terminals in the brain, and causes appetite suppression.
		Methcathinone is usually sold in quantities of one fourth of a gram, 1 gram, 3.5 grams ("8-ball") or an ounce (28.35 grams).
		Racemic methcathinone hydrochloride is intravenously self-administered by baboons, thus indicating that methcathinone produces reinforcing effects in this laboratory animal, and suggesting that the drug has a potential for abuse in the human population.
	en.wikipedia.org /wiki/Methcathinone (1522 words)

	[No title]
		Methcathinone hydrochloride increases spontaneous rodent locomotor activity, potentiates the release of radio-labelled dopamine from dopaminergic nerve terminals in the brain, and causes appetite suppression.
		The principal form of methcathinone distributed and abused is the hydrochloride salt of the l-enantiomer, which exists as a chunky powdered material, white to off-white in colour.
		Methcathinone abusers with experience in the abuse of other stimulants have reported that the effects produced by methcathinone are qualitatively similar to those produced by methamphetamine and/or cocaine.
	paranoia.lycaeum.org /stimulants/59.FR.31639 (3937 words)

	South Coast Recovery Centre (Site not responding. Last check: 2007-10-18)
		Methcathinone is a derivative of a naturally-occurring stimulant drug, cathinone, which is found in the "khat" plant, Cathula edulis, which is native to the horn of Africa and southern Arabian peninsula.
		Methcathinone reemerged in this country in 1989, when a University of Michigan student who was interning at Parke Davis stumbled across and stole samples of the drug and documentation of the manufacturing process.
		Methcathinone was classified a a schedule I controlled substance under the federal Controlled Substances Act on May 1, 1992, under the emergency scheduling procedure.
	www.scrc.co.za /cat/history.htm (262 words)

	Erowid Cathinone Vault : Methcathinone FAQ
		The methcathinone produced by this proceedure is no doubt not as pure as that which may be produced using a typical acid-base solvent extraction, but certainly rivals it nicely.
		Methcathinone was used as an antidepressant in the former soviet union.
		Methcathinone was considered by one company for marketing in the United States as an antidepressant in the 1950's, but was shelved due to "severe side effects".
	www.erowid.org /chemicals/cathinone/methcathinone_faq.shtml (4763 words)

	Methcathinone \| Methcathinone Facts \| Effects of Methcathinone
		Methcathinone - Methcathinone Facts - Effects of Methcathinone
		Methcathinone : Get Methcathinone Facts and learn about the Effects of Methcathinone.
		Little scientific research is available on the long-term effects of methcathinone.
	www.drugfree.org /Portal/drug_guide/Methcathinone (128 words)

	Methcathinone: Fast Facts
		Methcathinone or "cat" is a synthetic stimulant similar to the natural drug plant khat, which has been used for centuries in east Africa.
		First synthesized in 1928 and tested as both a diet drug and antidepressant, methcathinone's dangers were thought to outweigh its potential value and it was never distributed commercially in the United States.
		Still largely a regional phenomenon, methcathinone has expanded beyond its Midwestern base in recent years, mostly due to ease of manufacture and the continuing high demand for stimulant drugs.
	www.doitnow.org /pages/521.html (325 words)

	Drug Free Workplace - Drugs of Abuse - METHCATHINONE
		Methcathinone is one of the more recent drugs of abuse in the United States and was placed into Schedule I of the CSA in 1993.
		Known on the streets as "Cat," it is a structural analogue of methamphetamine and cathinone.
		Methcathinone has an abuse potential equivalent to methamphetamine, and produces amphetamine-like activity including superabundant energy, hyperactivity, extended wakefulness and loss of appetite.
	www.drugfreeworkplace.com /drugsofabuse/METHCATHINONE.htm (314 words)

	eMedicine - Stimulants : Article by Krishna Divadeenam, MD
		Methcathinone, isolated in 1957, was initially produced for use as an appetite suppressant.
		Methcathinone was not marketed because of the recognized addictive potential, but it emerged as a common drug of abuse in the former Soviet Union during the 1970s.
		Methcathinone was made a schedule I drug in 1992, and its use has not spread widely in the United States beyond the northern Midwest region.
	www.emedicine.com /med/topic3094.htm (4389 words)

	Drug Free Pennsylvania - Drugs of Abuse - Methcathinone
		Methcathinone is a stimulant that is a structural analogue of methamphetamine and cathinone.
		Short-term effects of methcathinone include: stimulation of heart rate and respiration, feeling of euphoria, loss of appetite, increased alertness, dilated pupils, and temperature may be slightly elevated.
		Acute intoxication at higher doses may also result in insomnia, tremors and muscle twitching, fever, headaches, convulsions, irregular heart rate and respirations, anxiety, restlessness, paranoia, hallucinations and delusions.
	www.drugfreepa.org /drugs/methcathinone.asp (205 words)

	Togdheer Online - Khat
		Physical dependence means a drug has altered the chemical composition of the body and the drug is needed to maintain the chemical functioning with the body.
		Some of the chemicals in methcathinone are the same chemicals used in over-the-counter asthma and cold medicines, paint solvent, auto battery acid, Drano, and paint thinner.
		Methcathinone is a highly addictive drug, similar to crack cocaine.
	www.togdheer.com /khat/cathinone.shtml (331 words)

	Methcathinone (Site not responding. Last check: 2007-10-18)
		Effects of Methcathinone Intoxication The most common means of taking methcathinone is snorting.
		Methcathinone is often used in binges lasting from two to six days, during which methcathinone is used repeatedly.
		Effects of short term intoxication are similar to those produced by crack cocaine or methamphetamine: stimulation of heart rate and respiration; feeling of euphoria; loss of appetite; increased alertness; pupils may be dilated; body temperature may be slightly elevated.
	www.angelfire.com /mn3/tiptop/Meth.html (161 words)

	Methcathinone
		Methcathinone is a lot like methamphetamine--someone makes it in a chemistry lab somewhere.
		Usually people snort it, but sometimes they smoke it or swallow it, too.
		Methcathinone keeps users awake, and sometimes makes them feel high as well.
	www.coalitionpathways.com /methcathinone.html (64 words)

	Methcathinone and Methylone
		The benzylic ketone moiety of methcathinone and methylone had a large (tenfold) negative impact on the abilities of these drugs to inhibit the vesicular monoamine transporter (VMAT2) compared to MA and MDMA.
		H]5-HT uptake were 103 ± 15 mM for methcathinone and 125 ± 16 mM for methylone.
		These results indicate that methcathinone and methylone are potent and selective inhibitors of plasma membrane catecholamine reuptake transporters, with more modest effects at the serotonin reuptake transporter.
	www.neurophys.wisc.edu /~cozzi/sfnabs24.html (277 words)

	[No title]
		Methcathinone is related to cathinone as methamphetamine is related to amphetamine, i.e.
		This would make it more potent than cocaine by six times in the rat and suggests the human figure of ten times cocaine potency in the human reported on USENET as been given on Belgium television is not unrealistic.
		Methcathinone Preparing the ephedrine/pseudoephedrine solution: Method A: Add enough water to completely dissolve pure ephedrine or pseudoephedrine.
	www.textfiles.com /drugs/ALT.DRUGS/syncat.txt (1559 words)

	[No title] (Site not responding. Last check: 2007-10-18)
		This substance is remarkably similar to the active ingredient found in the leaves of the khat tree which the loyal drug warriors on the network news blame for turning peace loving Somalis into murderous psychopaths.
		The active ingredient in the khat leaves is cathinone, which has the same structural relationship to methcathinone that amphetamine has to methamphetamine.
		The high produced by methcathinone is in many ways similar to methamphetamine.
	www.angelfire.com /creep/parazite/paraziteorg/p48-03.txt (2204 words)

	California Bar Journal - August, 1997
		Methcathinone was patented in the 1950s by the Parke-Davis Company, but it was never marketed.
		Methcathinone in its purest form is whitish and powdery-to-chunky in appearance.
		Ingestion of Methcathinone is usually by nasal inhalation or injection.
	www.calbar.ca.gov /calbar/2cbj/97aug/art-m2.htm (2523 words)

	RaveSafe Information on Qat (Kat) (Site not responding. Last check: 2007-10-18)
		Cathinone is a natural occurring amphetamine and ephedrine-like substance, Methcathinone is a much more potent form.
		The Methcathinone powder form is much quicker and stronger; the effects are much more condensed and heightened.
		This dependency is psychological and similar to cocaine dependency in some ways because one often one feels the urge to do another line soon after the first.
	www.ravesafe.org /drugz/kat.htm (755 words)

	The Benevolent & Protective Order of Elks of the USA
		Methcathinone is a highly addictive illegal drug with the street name "CAT." It is usually homemade from ingredients, including dangerous acids, obtained with little difficulty in most communities.
		People who manufacture methcathinone or assist others in doing so, perhaps by serving as go-betweens to buy ingredients, are being prosecuted under a number of federal statutes.
		Manufacturing or possession with intent to distribute, for instance, is a violation of Section 841(a)(1) of Title 21 of the United States Code and is punishable by a prison term of up to 20 years and a fine of up to $1 million.
	elks.org /drugs/da_cat.cfm (652 words)

	Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from ...
		Methamphetamine and methcathinone are psychostimulant drugs with high potential for abuse.
		Characteristics of drug use in methamphetamine and methcathinone users are summarized in Table 2.
		Hirata H, Cadet J (1997) p53-Knockout mice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies.
	www.jneurosci.org /cgi/content/full/18/20/8417 (4853 words)

	South Coast Recovery Centre (Site not responding. Last check: 2007-10-18)
		While research on the long-term effects of methcathinone use is just beginning in the United States, anecdotal reports from users in treatment in this country, and from published research in Russia, paint a similar picture.
		Anecdotal reports from patients in treatment facilities in Michigan and Wisconsin suggest that methcathinone is highly addictive, similar to crack cocaine, and some users report developing tolerance and withdrawal symptoms after just one incident of binging (six to ten days) on methcathinone.
		Addiction to methcathinone appears to be as difficult to treat as addiction to crack cocaine.
	www.scrc.co.za /cat/use.htm (190 words)

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