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| | Methenamine Elixir, chemical structure, molecular formula, Reference Standards (Site not responding. Last check: 2007-11-06) |
 | | Identification Heat a volume of Elixir,equivalent to about 1g of methenamine,with 10mLof 2Nsulfuric acid:formaldehyde is liberated,recognizable by its odor and by its darkening of paper moistened with silver ammonium nitrate TS.On the subsequent addition of an excess of 1Nsodium hydroxide to the solution,ammonia is evolved. |
 | | Standard preparation Transfer about 50mg of USP Methenamine RS,accurately weighed,to a 1000-mLvolumetric flask,dissolve in and dilute with water to volume,and mix.Proceed as directed under Assay preparation,beginning with Transfer a 2.0-mLportion of this stock solution to a 100-mLvolumetric flask.The concentration of USP Methenamine RSin the Standard preparationis about 1µg per mL. |
 | | in which Cis the concentration,in µg per mL,of USP Methenamine RSin theStandard preparation;Vis the volume,in mL,of Elixir taken;AUand ASare the absorbances of the Assay preparationand the Standard preparation,respectively;and BUand BSare the absorbances of the blanks from the Assay preparationand the Standard preparation,respectively. |
| www.newdruginfo.com /pharmacopeia/usp28/v28230/usp28nf23s0_m50770.htm (300 words) |
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