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Topic: Methylisothiazolinone

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Methylchloroisothiazolinone

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	Methylisothiazolinone - Wikipedia, the free encyclopedia
		Methylisothiazolinone or MIT, sometimes erroneously called methylisothiazoline, is a powerful biocide and preservative.
		Methylisothiazolinone is an antimicrobial used to control slime-forming bacteria, fungi, and algae in cooling water systems, fuel storage tanks, pulp and paper mill water systems, oil extraction systems, and other industrial settings.
		In 2002, there was an in vitro study of the neurotoxicity of MIT in the department of Neurobiology at the University of Pittsburgh.
	en.wikipedia.org /wiki/Methylisothiazolinone (272 words)

	Common ingredient in some shampoos (methylisothiazolinone) stunts developing neurons of rats (Site not responding. Last check: 2007-10-25)
		An antimicrobial agent found in some shampoos and hand creams and widely used in industrial settings inhibits the development of particular neuron structures that are essential for transmitting signals between cells, according to a University of Pittsburgh study presented today at Cell Biology 2004, the 44th annual meeting of the American Society for Cell Biology.
		Prolonged exposure to low levels of methylisothiazolinone (MIT) restricted growth of axons and dendrites of immature rat nerve cells in culture, apparently by disengaging the machinery of a key enzyme that is activated in response to cell-to-cell contact, and may have potentially damaging consequences to a developing nervous system, the researchers report.
		Senior author Elias Aizenman, Ph.D., professor of neurobiology at the University of Pittsburgh School of Medicine, became interested in MIT as an offshoot to his primary area of research on the mechanisms of neuronal cell death.
	www.news-medical.net /?id=6699 (889 words)

	Methylchloroisothiazolinone - Wikipedia, the free encyclopedia
		It is also used in glue production, detergents, paints, fuels and other industrial processes.
		Methylchloroisothiazolinone is known by the registered tradename Kathon CG when used in combination with methylisothiazolinone.
		It can be used in combination with alcohols and other long-chain organics in compounds such as methylchloroisothiazolinone ethylparaben benzalkonium chloride or methylchloroisothiazolinone 2-bromo-2-nitropropane-1,3-diol benzalkonium chloride.
	en.wikipedia.org /wiki/Methylchloroisothiazolinone (221 words)

	Welcome to VB Cosmetics (Site not responding. Last check: 2007-10-25)
		The third chakra, the Solar Plexus manipura chakra, is a warm color that is believed to stimulate the nervous system and affect the emotional mind.
		The calming effect of the blue chakra color, representing the throat or fifth chakra Vissudha, is a cool color that is believed to bring lightness, peace and calm that can help with sleep.
		The deep, rich color of indigo is associated with the sixth sense chakra, Ajna, the third eye, and is thought to build a positive outlook and bring inner strength.
	www.vbcosmetics.com /pages/chakraMasques.html (1190 words)

	Creative Collection
		Ingredients: Aqua (water) Sodium laurite sulfate, Lauramidopropyl betaine, Magnesium laurite sulfate, Sodium chloride, Glycol stearate, MIPA C12-15 pareth sulfate, Disodium laurite sulfosuccinate, Hydrolyzed soy protein, Polyquatermium-10, Polyquaterium-7, Cocamide DEA, Glycerin, Propylene glycol, Perfume, Tetra sodium EDTA, Imidazolidinyl urea, Benzyl alcohol, Methylchloroisothiazolinenone, Methylisothiazolinone.
		Ingredients: Aqua (water) Sodium laurite sulfate, Lauramidopropyl betaine, Magnesium laurite sulfate, Sodium chloride, Glycol stearate, MIPA C12-15 pareth sulfate, Disodium laurite sulfosuccinate, Vanilla planifolia, Polyquaterium-7, Cocamide DEA, Glycerin, Propylene glycol, Perfume, Tetra sodium EDTA, Imidazolidinyl urea, Benzyl alcohol, Methylchloroisothiazolinenone, Methylisothiazolinone, CI 19140.
		Disodium laurite sulfosuccinate, Hydrolyzed wheat protein, Polyquaterium-7, Cocamide DEA, Glycerin, Propylene glycol, Perfume, Tetra sodium EDTA, Imidazolidinyl urea, Benzyl alcohol, Methylchloroisothiazolinenone, Methylisothiazolinone, CI 19140, CI 14720..
	www.helenseward.us /creative_collection.htm (989 words)

	EWG in the News \|\| Story Content (Site not responding. Last check: 2007-10-25)
		Your revitalizing daily shampoo might have been formulated to add volume and shine, but consumer watchdogs say the scads of chemicals used in cosmetics aren't adequately assessed for safety by either the federal government or the manufacturers.
		Methylisothiazolinone -- shortened to MIT for obvious reasons -- is often added to water-based shampoos and hand lotions to prevent bacteria growth, said Pitt neurobiologist Elias Aizenman, the study's senior author.
		There is mounting evidence that neurodegenerative diseases such as Parkinson's or Alzheimer's could be exacerbated by exposure to chemicals in the environment, but there is little evidence about the potential effect on the brain of many commonly used substances, Aizenman said.
	www.ewg.org /news/story.php?print_version=1&id=3392 (1243 words)

	Methylisothiazolinone. (Site not responding. Last check: 2007-10-25)
		For information on the "classification" and "use", please click here, and for more information on preservatives as used in cosmetic skin care products, please click here.
		Methylisothiazolinone is used in the following of our products
		Statements made on the products, ingredients and general information have not been evaluated by the FDA and should not be seen as health claims.
	www.dermaxime.com /methylisothiazolinone.htm (116 words)

	philosophy: birthday party, the
		strawberry ice cream: water (aqua), tea-lauryl sulfate, cocamidopropyl betaine, glycol stearate, tea-peg-3 cocamide sulfate, disodium laureth sulfosuccinate, sodium chloride, glycerin, fragrance (parfum), polyquaternium-7, peg-150 distearate, tocopheryl acetate, citric acid, methylchloroisothiazolinone, methylisothiazolinone, red 33 (ci 17200).
		chocolate frosting: water (aqua), tea-lauryl sulfate, ppg-2 hydroxyethyl cocamide, cocamidopropyl betaine, glycol stearate, caramel, disodium laureth sulfosuccinate, sodium chloride, glycerin, glyceryl polymethacrylate, fragrance (parfum), polyquaternium-7, peg-150 distearate, tocopheryl acetate, citric acid, sodium benzotriazolyl butylphenol sulfonate, buteth-3, tributyl citrate, propylene glycol, methylchloroisothiazolinone, methylisothiazolinone, red 33 (ci 17200).
		vanilla birthday cake: water (aqua), tea-lauryl sulfate, ppg-2 hydroxyethyl cocamide, cocamidopropyl betaine, glycol stearate, disodium laureth sulfosuccinate, sodium chloride, glycerin, glyceryl polymethacrylate, fragrance (parfum), polyquaternium-7, peg-150 distearate, tocopheryl acetate, citric acid, sodium benzotriazolyl butylphenol sulfonate, buteth-3, tributyl citrate, propylene glycol, methylchloroisothiazolinone, methylisothiazolinone, yellow 5 (ci 19140), red 40 (ci 16035)
	www.philosophy.com /web/store/product_10001_10001_-1_43529_ (291 words)

	philosophy: bridal party, the
		bridal bouquet: water (aqua), tea-lauryl sulfate, ppg-2 hydroxyethyl cocamide, cocamidopropyl betaine, glycol stearate, disodium laureth sulfosuccinate, sodium chloride, glycerin, glyceryl polymethacrylate, fragrance (parfum), polyquaternium-7, peg-150 distearate, tocopheryl acetate, citric acid, sodium benzotriazolyl butylphenol sulfonate, buteth-3, tributyl citrate, propylene glycol, tetrasodium edta, methylchloroisothiazolinone, methylisothiazolinone.
		bubbly: water (aqua), sodium laureth sulfate, ppg-2 hydroxyethyl cocamide, lauryl betaine, disodium laureth sulfosuccinate, glycerin, fragrance (parfum), polyquaternium-7, peg-7 glyceryl cocoate, polyquaternium-10, isostearamidopropyl morpholine lactate, tocopheryl acetate, sodium benzotriazolyl butylphenol sulfonate, buteth-3, tributyl citrate, sodium chloride, citric acid, tetrasodium edta, methylchloroisothiazolinone, methylisothiazolinone, yellow 5 (ci 19140), red 40 (ci 16035).
		wedding cake: water (aqua), tea-lauryl sulfate, ppg-2 hydroxyethyl cocamide, cocamidopropyl betaine, glycol stearate, disodium laureth sulfosuccinate, sodium chloride, glycerin, glyceryl polymethacrylate, fragrance (parfum), polyquaternium-7, peg-150 distearate, tocopheryl acetate, citric acid, sodium benzotriazolyl butylphenol sulfonate, buteth-3, tributyl citrate, propylene glycol, methylchloroisothiazolinone, methylisothiazolinone, yellow 5 (ci 19140), red 40 (ci 16035)
	www.philosophy.com /web/store/product_10001_10001_-1_43533_30029 (256 words)

	Pre de Provence French Bath Soap - Pre de Provence (Site not responding. Last check: 2007-10-25)
		LAVENDER - palm and coconut base, lavender flowers, fragrance, phenoxyethanol, bht, methylchloroisothiazolinone and methylisothiazolinone solution.
		SAGE - palm and coconut base, perfume, sage, CI 77288, phenoxyethanol, methylchloroisothiazolinone and methylisothiazolinone.
		In the South of France, near the foothills of the Alps, Provence is a land where herbs and flowers abound.
	www.vickerey.com /i19sp01.html (131 words)

	philosophy: health bar, the (Site not responding. Last check: 2007-10-25)
		melon daiquiri: water (aqua), tea lauryl sulfate, ppg-2 hydroxyethyl cocamide, cocamidopropyl betaine, glycol stearate, sodium chloride, disodium laureth sulfosuccinate, glycerin, glyceryl polymethacrylate, propylene glycol, fragrance, polyquaternium-7, peg-150 disterate, tocopheryl acetate, citric acid, sodium benzotriazolyl butylphenol sulfonate, buteth-3, tributyl citrate, methylchloroisothiazolinone, methylisothiazolinone, red 4, yellow 5, red 33.
		mimosa: water (aqua), tea-lauryl sulfate, ppg-2 hydroxyethyl cocamide, cocamidopropyl betaine, glycol stearate, disodium laureth sulfosuccinate, sodium chloride, glycerin, fragrance (parfum), glyceryl polymethacrylate, polyquaternium-7, peg-150 distearate, tocopheryl acetate, citric acid, sodium benzotriazolyl butylphenol sulfonate, buteth-3, tributyl citrate, methylchloroisothiazolinone, methylisothiazolinone, propylene glycol, yellow 5 (ci 19140), red 4 (ci 14700).
		margarita: ter (aqua), tea lauryl sulfate, ppg-2 hydroxyethyl cocamide, cocamidopropyl betaine, glycol stearate, disodium laureth sulfosuccinate, glycerin, glyceryl polymethacrylate, propylene glycol, fragrance, polyquaternium-7, peg-150 disterate, tocopheryl acetate, citric acid, sodium benzotriazolyl butylphenol sulfonate, buteth-3, tributyl citrate, sodium chloride, methylchloroisothiazolinone, methylisothiazolinone, yellow 5, blue 1.
	www.philosophy.com /webapp/wcs/stores/servlet/ProductDisplay?catalogId=10001&storeId=10001&productId=42503&langId=-1&parentCategoryId=30028 (365 words)

	Study on methylisothiazolinone in shampoo lacks a credible scientific basis (Site not responding. Last check: 2007-10-25)
		Study on methylisothiazolinone in shampoo lacks a credible scientific basis
		The abstract on Methylisothiazolinone (MI), presented at the Cell Biology 2004 meeting of the American Society for Cell Biology, lacks a credible scientific basis in suggesting that MI could be a safety issue for consumers using personal care products.
		In determining the safety of any ingredient, a major factor is exposure.
	www.news-medical.net /?id=6719 (533 words)

	Preservative Causes Cell Death
		The preservative, methylisothiazolinone, is a biocide used to prevent bacteria from developing.
		According to Aizenman, lead researcher on the study, the chemical caused neurons to die in experiments with rats' brain cells.
		But in the case of methylisothiazolinone, we see that the cosmetic industry's review board knew there were risks associated with it, but declared it safe for use."
	www.nfm-online.com /ASP/articleDisplay.asp?strArticleId=1270&strSite=NFMSITE&Screen=CURRENTISSUE (357 words)

	ROHM AND HAAS COMPANY RECEIVES JAPANESE APPROVAL FOR ITS NEOLONEâ¢ PRESERVATIVE IN COSMETIC PRODUCTS
		Neoloneâ¢ PE is a broad spectrum preservative based on methylisothiazolinone and phenoxyethanol.
		Neoloneâ¢ MxP is a broad spectrum preservative based on methylisothiazolinone, methylparaben, propylparaben and phenoxyethanol.
		Neoloneâ¢ 950 is a broad spectrum bactericide ofÂ 9.5% methylisothiazolinone
	vocuspr.vocus.com /vocuspr30/DotNet/Newsroom/Query.aspx?SiteName=RohmHaas&Entity=PRAsset&SF_PRAsset_PRAssetID_EQ=93686&XSL=PressRelease&Cache= (148 words)

	In Vitro Neurotoxicity of Methylisothiazolinone, a Commonly Used Industrial and Household Biocide, Proceeds via a Zinc ...
		In Vitro Neurotoxicity of Methylisothiazolinone, a Commonly Used Industrial and Household Biocide, Proceeds via a Zinc and Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase-Dependent Pathway -- Du et al.
		Neurodegenerative disorders in humans may be triggered or exacerbated by exposure to occupational or environmental agents.
		Methylisothiazolinone, A Neurotoxic Biocide, Disrupts the Association of Src Family Tyrosine Kinases with Focal Adhesion Kinase in Developing Cortical Neurons
	www.jneurosci.org /cgi/content/full/22/17/7408 (5951 words)

	Hot Topics
		Methylisothiazolinone and Methylchloroisothiazolinone (MI and MCI, respectively) are organic compounds that are effective preservatives in a variety of cosmetic products like shampoos, conditioners, and eye makeup removers.
		These compounds offer antimicrobial benefits, preventing the growth and reproduction of bacteria, mold, and fungi.
		Having reviewed the latest research performed by the cosmetic industry, the FDA, and other qualified sources, we can assure our customers that methylisothiazolinone and methylchloroisothiazolinone are safe and effective as preservatives in Nu Skin products.
	www.nuskin.com /corp/science/hottopics/methylisothiazolinone.shtml (585 words)

	Read your shampoo's label: Study finds common ingredient stunts developing neurons of rats
		The meeting is being held Dec. 4 — 8 at the Washington Convention Center.
		Clearly, more study is needed, with both scientists and government regulators equally engaged," added Dr. Aizenman.
		NOTE TO EDITORS: This abstract, Lack of Phosphorylation of Tyrosine 576 of Focal Adhesion Kinase Correlates to Neurite Outgrowth Deficiency Following Methylisothiazolinone Treatment in Cultured Cortical Neurons (Poster Presentation 300), is being presented at 1:30 p.m., Sunday, Dec. 5 in Session 123 Focal Adhesions.
	www.eurekalert.org /pub_releases/2004-12/uopm-rys113004.php (966 words)

	JAPAN APPROVES USE OF NEOLONE PRESERVATIVE IN COSMETICS
		About Us 05 November 2004 - Rohm & Haas Co Rohm and Haas Co has announced that methylisothiazolinone, the key ingredient in its Neolone preservative has been approved by the Japanese Ministry of Health, Labour and Welfare (MHLW)/Pharmaceutical Affairs Bureau.
		Rohm and Haas Co has announced that methylisothiazolinone, the key ingredient in its Neolone preservative has been approved by the Japanese Ministry of Health, Labour and Welfare (MHLW)/Pharmaceutical Affairs Bureau.
		The MHLW has added methylisothiazolinone to the positive list of preservatives approved for use in leave-on and rinse-off cosmetic products at a maximum dosage of 100 ppm.
	www.newmaterials.com /news/724.asp (321 words)

	Methylchloroisothiazolinone (and) methylisothiazolinone (Site not responding. Last check: 2007-10-25)
		New systems may be introduced that are stabilised with other salts (copper) or contain the less allergenic fraction methylisothiazolinone.
		Methylchloroisothiazolinone (and) methylisothiazolinone is the INCI name for the preservative and this is the name that must appear on cosmetic ingredient listing in the European and USA markets if a product contains it.
		Therefore, it is easy to determine consumer exposure (qualitative) to the preservative from use of cosmetic products.
	orgs.dermis.net /content/e05eecdrg/e05news/e686/e706/index_ger.html (368 words)

	Shower & Bath Gels Ingredients
		Methylisothiazolinone, May contain Blue 1, Red 33, Red 4,
		Scthiazolinone, D and C Red 33, FD and C Blue 1.
		methylisothiazolinone, DandC Red 4 (CI 14700), FDandC Blue 1
	www.sugarpinebeauty.com /showerbathgeling.html (128 words)

	New Page 1
		The results from your patch testing showed a positive reaction (contact allergy) to Methylchloroisothiazoline/Methylisothiazolinone.
		Your immune system reacts with its defense mechanisms with each exposure of Methylchloroisothiazoline/ Methylisothiazolinone to your skin.
		It is unknown why certain individuals develop allergic sensitivities.
	www.orlandoskindoc.com /test.methycloroisothiazolinone.htm (243 words)

	Eucerin Original Moisturizing Creme - 16 oz ZUCKERMANPHARMACY.COM
		Can be used safely to help relieve dry skin associated with certain prescribed medications.
		Water, Petrolatum, Mineral Oil, Ceresin, Lanolin Alcohol, Methylchloroisothiazolinone, Methylisothiazolinone.
		Apply liberally as needed or as directed by a physician.
	www.zuckermanpharmacy.com /product.cfm/hurl/31914.html (62 words)

	Candles~Bath & Body~ Shower Gel~Wellington Oils at Kayloma's (Site not responding. Last check: 2007-10-25)
		This creamy conditioner is perfect for daily use with all types of hair.
		It is recommended for customers who wish to maintain normal, healthy, manageability of the hair.
		This all natural formula combines a superior blend of imported sea salt with nourishing sweet almond oil and sunflower oil.
	www.kaylomafarm.com /BathandBody.html (722 words)

	AromaCare Pet Shampoo and Spray
		Infused with natural essential oils of lavender, ylang ylang, jasmine and sandalwood, this shampoo leaves the skin soft and the haircoat supple and tangle free.
		Lavender Freshening Spray for Dogs and Puppies is infused with natural essential oils to calm and soothe.
		Eucalyptus Freshening Spray for Dogs and Puppies is infused with natural essential oils to cool and invigorate both inside and out.
	www.drsfostersmith.com /product/add_info.cfm?pCatId=12729 (478 words)

	ALLERGY - Pet Medications (Site not responding. Last check: 2007-10-25)
		Combines humectants, emollients, emulsifiers, and Omega-6 Fatty Acids for skin hydration.
		Water, quaternium-18, cetearyl alcohol and polysorbate 60, stearamidopropyl dimethylamine lactate, sodium lactate, safflower oil, hydrolyzed collagen, PEG-8 stearate, glycerin, polyquaternium-7, fragrance, methylochloroisothiazolinone and methylisothiazolinone.
		After bath creme rinse for improved luster and sheen of hair coat.
	www.pet-medication.bz /detail.asp?catid=7&id=10785 (133 words)

	[No title]
		70 Classification of chemical products containing methylchloroisothiazolinone/ methylisothiazolinone (MCI/MI) Since the first reports on hypersensitivity to Kathon CG (1984 - 1985) there have been many reports on contact allergy, mainly from European countries but also from USA and Japan.
		Contact Dermatitis 1986: 15: 211-214 Tosti A. Prevalence and sources of Kathon CG sensitization in Italy.
		Contact Dermatitis 1988: 18: 179-180 Bruze M, Gruvberger B, Hradil E. Occupational allergic contact dermatitis due to methylisothiazolinones in a cleansing cream.
	ecb.jrc.it /classlab/4695a70-I.doc (1587 words)

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