
	Where results make sense

Topic: MicroRNA

Related Topics

MiRNA

Markeaton

Osmaston

	RNA interference - Wikipedia, the free encyclopedia
		The native cellular purpose of the RNA interference machinery is not well characterized, but it is known to be involved in microRNA (miRNAs) processing and the resulting translational repression.
		MicroRNAs, which are encoded in the genome and have a role in gene regulation, typically have incomplete base pairing and only inhibit the translation of the target mRNA; by contrast, RNA interference as used in the laboratory typically involves perfectly base-paired dsRNA molecules that induce mRNA cleavage.
		In plants, this mechanism was first shown in the "JAW microRNA" of Arabidopsis; it is involved in the regulation of several genes that control the plant's shape.
	en.wikipedia.org /wiki/RNA_interference (1804 words)

	Current Research Focusing on Euchromatin Within the Cell Nucleus.
		Esquela-Kerscher A, and Slack FJ, "Oncomirs — microRNAs with a role in cancer".
		Chen C-Z, "MicroRNAs as Oncogenes and Tumor Suppressors".
		Houbaviy HB, Murray MF, and Sharp PA, "Embryonic Stem Cell-Specific MicroRNAs".
	www.euchromatin.net /current1.html (11122 words)

	News & Features: Bioinformatics reveals unique characteristics of Human microRNA-mRNA interactions
		Several microRNA targets have been identified in lower organisms, but only one mammalian microRNA target has yet been validated experimentally.
		And, the stretches of perfect complementarity within microRNA hits onto outlier mRNAs were not biased near the 5'-end of the microRNA.
		The analysis supports the notion that sequence complementarity is the basis by which microRNAs recognize their biological targets, but raises the possibility that human microRNA-mRNA target interactions follow different rules than have been previously characterized in Drosophila and C. elegans.
	www.iscid.org /boards/ubb-get_topic-f-1-t-000184.html (412 words)

	Christopher Burge Lab
		A major current effort is to develop computational methods to identify splicing enhancer and repressor motifs and to test the function of these motifs using in vivo splicing assays.
		We are also using a combination of computational and experimental methods to study alternative splicing, a common mechanism of gene regulation in vertebrates.
		In collaboration with the David Bartel lab (Whitehead/MIT), we are developing computational methods to identify genes encoding "microRNAs" - a large class of 21-24-nt non-coding RNAs that have probable regulatory roles in animals and plants - and to predict their functions.
	genes.mit.edu /chris (1705 words)

	work
		A quarterly printed publication which caters to those who build SciFi Fantasy Vehicular and Figure Models.
		Provide scientific and technical support information on microRNA and small interfering RNA application in gene expression research.
		A comprehensive for people interested in practical weight management information including healthy eating sensible dieting tips nutrition and weight loss maintenance.
	www.afterpublication.com /lateone/sbw.htm (616 words)

Try your search on: Qwika (all wikis)