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Topic: Microtome


In the News (Thu 31 Dec 09)

  
  Microtome - Patent 5535654
Microtome in accordance with claim 4, characterized in that the electronic control (44) is connected to at least one sensor means (58,59) for detecting a reversal position of the sample holder.
Microtome in accordance with claim 5, characterized in that said reversal position is a position of said sample holder at the beginning of said cutting movement (arrow 54).
Microtome in accordance with claim 5, characterized in that said reversal position is a position of said sample holder at the end of said cutting movement (arrow 54).
www.freepatentsonline.com /5535654.html   (2919 words)

  
 Microtome - Patent 5752425
A microtome as defined in claim 1, wherein said first feed means of said micro-feed mechanism is constituted by a first fixed member securely fixed on said machine base and a first movable member mounted movably on top of said first fixed member for movements in a direction at an angle of +.theta.
In the case of the microtome of the arrangements just described, the first and second linear motor stages are displaced in two intersecting directions crossing at an intersection angle of 2.theta., and the specimen holder support arm is located in an upper lifted position in an initial state in the direction of Z-axis.
The microtome 1' of the arrangements just described operates substantially in the same manner as the microtome 1 of the foregoing first embodiment except that the cutting knife 6' is finely fed by the micro-feed mechanism 7.
www.freepatentsonline.com /5752425.html   (5364 words)

  
 Microtome - Wikipedia, the free encyclopedia
Cryosections can also be used in immunohistochemistry as freezing tissue does not alter or mask its chemical composition as much as preserving it with a fixative.
Electron microscopy: after embedding tissues in epoxy resin, a microtome equipped with a glass or diamond knife is used to cut very thin sections (typically 60 to 100 nanometers).
A recent development is the laser microtome, which cuts with a femtosecond laser instead of a mechanical knife.
en.wikipedia.org /wiki/Microtome   (350 words)

  
 EDUCATION SCIENCE - Microscope
The Microtome is equipped with a ball and flange type object holder to get exact centring of specimen, knife holder with lateral movement permitting use of complete knife edge and has a feed range from 1-25 microns in steps of one micron each.
The knife supplied with the Microtome is forged from fine grain tool steel, tested for micro-structures and it is also heat treated for optimum rigidity and sharpness.
The knife supplied with the microtome is fabricated from fine grain steel tested for micro-structure, heat treated for optimum rigidity and sharpness.
www.educationscience.com /microscope/microtomes.htm   (703 words)

  
 The microtome: function and design © Woods and Ellis 2000
The distance moved is pre-selected using a scale setting on the microtome body and usually extends between 0.5 and 50 microns on microtomes cutting thin sections and from less than 60 nm to over 500 nm on machines cutting ultra thin sections.
The microtome operation is based upon the rotary action of a hand wheel activating the advancement of a block towards a rigidly held knife.
Microtome knives of hardened steel are made to four different profiles for cutting various materials (Fig 7).
home.primus.com.au /royellis/microt/microt.htm   (7686 words)

  
 Neurogenetics at UT Health Science Center
Estimations of the numbers of nuclei in microtome sections are frequently made in some branches of histology, particularly in the study of endocrine glands, hemopoietic organs and the central nervous system.
Since microtome sections are commonly roughly the same thickness as the nuclear length, the error in extrapolating from A to the number of nuclei per unit volume of tissue may often reach 100%.
The error in comparing on the basis of counts in sections two tissues whose nuclear size is different is much less serious, since it follows from equation (1) that a given change in L produces a disproportionately smaller change in A when P is held constant [RW2].
www.nervenet.org /papers/AberFP.html   (3734 words)

  
 Cutting It Fine
Microtomes are devices for cutting very thin slices to be examined under the microscope.
The largest microtome in the collection, shown in Figure 5, is also by the Cambridge Instrument Co. It is a lever-operated sledge microtome of a design introduced in 1909 which could cut specimens such as bones in sections up to 40 square cm.
The Museum holds two microtomes of Japanese manufacture, a rotary instrument by Y. Takahashi and a radial instrument by J. Oiso and Co. Both were made in the Hongo district of Tokyo (where the University of Tokyo is located) and possibly date from the 1920s.
members.optusnet.com.au /jph8524/JHmicrotomes.htm   (1205 words)

  
 Microtome Knife Sharpener
The goal of this holder design is to minimize the operator skill needed to sharpen a microtome knife, necessary since I had never seen a microtome knife prior to sharpening this one.
In use, the upper end of the hone or strop is kept in contact with the upper block while the abrasive section of the tool is in contact with the knife, thus ensuring that the angle built into the holder is transferred to the knife.
In my microtome the knife can only be moved a short distance sideways before it cannot be clamped, so only the central 3 inches or so of the knife could possibly be used.
webpages.charter.net /balplanman/Sharpener/Sharpener.html   (2983 words)

  
 Laboratory Equipments,Laboratory Supplies,Laboratory Instruments and Products,Glassware ...
This is a portable, handy and simple microtome recommended for laboratories, field work etc. For sectioning of fresh tissues.
This is a sturdy and well designed microtome (Cambridge type) which can cut sections of tissues from 2-24 microns in steps of 2 microns each.
The microtome is equipped with a ball and flange type object holder to get exact centering of specimen, knife holder with lateral movement permitting use of complete knife edge and has feed range from 1-25 microns in steps of 1 micron each.
www.narang.com /laboratory_equipments/microtomes.php   (382 words)

  
 Microtome Publishing
With open access print archiving, an open access journal prepares annually a copy of all articles it has published during the year; copies are then printed on acid-free paper, bound to library standards, and distributed to a set of libraries to serve not as access copies but as archival copies for long-term deposit.
Microtome Publishing was founded by Stuart Shieber, Welch Professor of Computer Science at Harvard University, to provide just such innovative services in support of open access.
Microtome Publishing was founded in 2002 by Stuart M. Shieber, Harvard College Professor and James O. Welch, Jr.
www.mtome.com /News/jmlr-release.html   (788 words)

  
 Microtome Depot - High Quality Microtomes for Biological Microscope Slide Preparation
Microtome Depot is the brand for high quality microtomes for biological microscope slide preparation.
Our full line of microtomes are able to meet the needs of microscopists and clinical laboratory technicians.
A microtome is a precision instrument capable of taking a thin slice of biological tissue material.
www.microtomedepot.com   (181 words)

  
 SDR - Microtomes
The new SureCut M3500 Radial Microtome has a look that is revolutionary, a feel that is marvelous, and a range of functions and capabilities that will please the most demanding of users.
The popular 5040 microtome is of rotary retracting, self-lubricating design and has a heavy cast alloy base and cutting arm.
The 8000 microtome is well suited to cutting a wide range of materials including bone, plastics, resins and wood as well as large area soft tissues and is the first of its kind to incorporate retraction on the return stroke.
www.sdr.com.au /microtomes.html   (676 words)

  
 Hacker Instruments & Industries, Inc. - Microtomes
From routine histology to research applications and materials R and D, H/I Microtomes will provide you with the quality and performance you need.
The 5040 microtome series is suitable for routine pathology, teaching laboratories and research.
Freezing stage available in two sizes for standard rotary, sliding and freezing microtomes or for large sliding microtomes.
www.hackerinstruments.com /microtomes.htm   (287 words)

  
 Rajesh Scientific Works
Microtome has a feed range of 1-25 microns in steps of 1 micron each.
The feed indicator, located in front of Microtome is operated by the latest "CAM DRIVE SYSTEM" for accurate feed setting from 1-50 microns in steps of 1micron.
A portable and very precise automatic knives sharpening equipment for sharpening of all Microtome knives upto 180 mm in length and equipped with automatic timer to adjust sharpening time.
www.rajeshlab.com /Microtome.php   (359 words)

  
 Atlas Surgical - Rotary Microtome
When the limit of the feed is reached at the end, a safely device automatically disengages the feed mechanism to prevent jamming and damage to the feed screws.
The feed indicator is located in the front and feed settings controlled by a knurled knob at the back of the Microtome, to adjust section thickness from 1 to 50 microns in steps of one microns each.
The knife supplied with the Microtome is fabricated from high carbon fine grain tool steel which is heat-treated for proper temper and tested for Micro Structures.
www.sahaj.com /rotarymicrotome.html   (286 words)

  
 Microtome,Microtome Parts,Blades,Rotary Microtome,Razor, NET Brand Microtomes-High Quality Microtomes   (Site not responding. Last check: 2007-10-20)
The feed indicator, located in front of microtome is operated by the latest 'CAM DRIVE SYSTEM' for accurate feed setting from 1 - 50 micron in steps of 1 micron.
The salient features include independent feed mechanism with automatic safety device, universal knife holder with lateral movements permitting use of the entire knife edge, universal vice type object holder for accurate centering of the specimen.
Microtome Razors: Rotary Microtome Razors fabricated from imported fine grain tool steel, heat treated and tested for micro-structure.
www.laboratory-supply.com /microtome.html   (546 words)

  
 TBS - Triangle Biomedical Sciences - Microtomes
Use this microtome to section paraffin embedded biological specimens or industrial materials.
Use this microtome to section paraffin or plastic embedded specimens or industrial materials.
Use this microtome to section paraffin or plastic embedded specimens, hard specimens such as mineralized bone, or industrial materials.
www.trianglebiomedical.com /products/Microtome_details.html   (630 words)

  
 Microtome Workshop
Colin then described the main features of three types of microtome blade in common use, which were; the 'classical' rocker microtome blade made by John Heiffor, the German-made 'Jung' wedge or 'C' profile blade, and the knife made by Cambridge Instruments specifically for their Cambridge Rocker.
Colin suggested that a sheet of 6mm thick plate glass, cut to a width appropriate for the particular length of knife, could be usefully employed as a knife-sharpening surface.
were invited to practice section cutting with their own microtomes Colin demonstrated how to attach wax blocks to the block-holder (also known as the 'chuck') of the microtome, using a heated spatula.
www.nhm.ac.uk /hosted_sites/quekett/Reports/Microtome-ws.html   (988 words)

  
 MicroTome, Deconvolution, digital microscopy, medical imaging, scientific software, VayTek, vaytek
MicroTome is deconvolution software from VayTek, Inc. For researchers who need the highest quality output from their digital imaging system, MicroTome has been the software of choice for removing out-of-focus haze for more than fifteen years.
To increase MicroTome's flexibility for users, the new version works as standalone software, or it can be used in conjunction with Image Pro from Media Cybernetics.
MicroTome makes 100 million calculations in about 4 seconds, the number required to clean up a single 512 x 512 image using the nearest neighbor algorithm.
www.vaytek.com /MicroTomeWin.html   (719 words)

  
 RM2125 Microtome
The Leica RM2125 microtome comes in two different versions - the Leica RM2125 and Leica RM2125 RT (with specimen retraction, trimming and slot cover as additional features).
designed for the routine histopathology laboratory where the manual use of a rotary microtome is preferred.
For those users preferring a manual rotary microtome, the Leica RM2125 is the ideal solution.
www.mcbaininstruments.com /RM2125.htm   (139 words)

  
 BD Biosciences Bioimaging: MicroTome Deconvolution Software   (Site not responding. Last check: 2007-10-20)
BD Biosciences Bioimaging provides the MicroTome for Macintosh package for correcting optical blurring and remove out-of-focus haze from 3D images.
MicroTome includes the constrained-iterative program, MicroTome CI, and the nearest-neighbor software, HazeBuster, and can deconvolve both fluorescence and bright-field images.
MicroTome uses constrained iterative algorithms by Agard and Sedat (UCSF) to deconvolve the blurred image of the sample.
www.scanalytics.com /product/microtome   (302 words)

  
 SEPS Safety Handbook - Microtomes and Surgical Blades
A guard must be provided to protect the operator from the knife which may project from the microtome In addition, a power interlock must be fitted to prevent unexpected operation.
The utmost care is required in the handling of microtome knives.
Always carry the knife, in its case, to the microtome.
www.gla.ac.uk /seps/publications/safetyhandbook/microtomes.html   (335 words)

  
 Microtomes
Mechanical rotary microtomes for paraffin sectioning in routine and research laboratories.
A unique sliding Microtome with automatic micro/macro feed system, specimen retraction during return travel, caged and maintenance-free precision cross roller bearings.
Sliding Microtome with caged, maintenance-free precision cross roller bearings for paraffin sectioning techniques.
www.mikronet.com /microtomes.htm   (145 words)

  
 Larry Legg's Microscopy Projects - Project 2
The surface of the microtome consists of a coating that's likely to snag a cutting tool.
Ideally, the microtome would be greatly improved (but so would the cost) by having a round glass plate surface.
In later sections of this project, I will be using a modified bench microtome, just like this, to show you the rest of the process.
www.microscopy-uk.org.uk /larry/project3/proj3_2b.html   (593 words)

  
 Microtome
That is why Microtome has always made its #1 priority providing the best possible reticle protection.
Microtome has been supplying SMIF-based reticle handling solutions for over fifteen years.
The experience base of our staff includes several years of direct responsibility for reticle handling in one of the world's premier lithography companies.
www.microtome.com   (308 words)

  
 Microtomes - New Surplus Refurbished Used Equipment
This Olympus 4060 E microtome is in immaculate condition and fully refurbished ensuring o...
The Microm 335 E microtome is an electronic microtome featuring motor driven coarse feed, trim feed and section advance.
The Reichert / Leica RM2030 microtome is a widely popular, reliable instrument that has been considered a standard in histology and pathology labs throughout the worl...
www.labx.com /atlabx/allcats/Microtomes.cfm   (632 words)

  
 Jencons Scientific, Inc. : Liquid Handling Products / Laboratory Equipment & Supplies
Bright Instrument Company Limited has been manufacturing cryostats, microtomes, freezing units and accessories for pathology, histopathology, immunology, life sciences, research and industrial testing and quality control laboratories world-wide for over 30 years.
Recent tests have shown that excellent quality sections are obtained with very rapid turning of the operating handle, thus enabling busy pathology laboratories to produce quality sections even quicker than before.
The M3500 is available as a basic microtome with hand operation or as a semi automatic microtome with motorised advance/rewind facilities.
www.jenconsusa.com /products_specs_1.cfm?id=114   (355 words)

  
 LabScientific, Inc.
This microtome offers a highly precise engineering that guaranteees accurate and reliable sections day in and day out.
This competitively designed microtome is made to meet the needs of most low volume histology and pathology laboratories.
The microtome is built with high quality control standard to give your laboratory a reliable precise and smooth microtome.
www.labscientific.com /cytology_microtomes.asp   (254 words)

  
 Leica, Tissue-Tek Accu-Edge, Disposable Microtome Blades, Cryostat Disposable Blade Holders, Microtome Lubrication
The adapter can be used with most microtomes, and it is designed to accept Tissue-Tek® embedding rings, process/embedding cassettes or Uni-Cassettes®.
This device is designed to hold paraffin blocks securely in the microtome during sectioning, and quickly release the block after it is done sectioning or exchanged to another block.
High and low profile disposable blades for use with all Leica microtomes as well as the Cryocut and Cryostat.
www.emsdiasum.com /microscopy/products/histology/sectioning.aspx   (1189 words)

  
 Microtome disposable blade apparatus (US4700600)
A microtome apparatus includes a disposable blade holder adapted to receive both thick and thin blades and for cutting frozen sections to mount an anti-roll plate assembly utilizing a magnet as the holding mechanism.
(b) a knife clamp adapted to clamp a conventional non-disposable microtome knife, said clamp being movable laterally and tiltable with respect to the specimen for appropriate precision positioning of the knife cutting edge;
(c) a substantially rectangular disposable blade of a selected uniform width and thickness, having one longitudinal edge precision sharpened to microtome knife quality for cutting and the opposed edge free of the conventional guard member, being of substantially less flexibility than the conventional double edge wafer blade while being held clamped; and
www.delphion.com /details?pn10=US04700600   (272 words)

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