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| | Special: DNA unraveled |
 | | Ernster and Luft implicated a defect in mitochondrial energy metabolism and showed that this patient's muscle mitochondria could make only a fraction of the energy they should normally produce; the unconverted fuel was diverted into heat production. |
 | | Nevertheless, many symptoms of mitochondrial diseases, such as muscle weakness, diabetes, vision loss, hearing loss, and dementia, are also the hallmarks of aging. |
 | | One well-known result of such investigations has been the identification of the "mitochondrial Eve," a hypothetical woman (or, more accurately, group of women) who lived about 200,000 years ago in Africa: the mothers of us all, as everyone today carries the progeny of their mitochondrial DNA. |
| www.columbia.edu /cu/21stC/issue-1.3/dna-mitoch.html (1202 words) |
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