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Topic: Mitochondrial genome


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  The mitochondrial genome
The human mitochondrial genome is a small circular DNA molecule 16 568 bp in length containing 37 genes.
Mitochondrial diseases include Leber's hereditary optic neuropathy, in which there is loss of vision often combined with cardiac arrhythmia, and Kearns-Sayre syndrome, which involves paralysis of the eye muscles, dementia and seizures.
Interestingly, all mitochondrial diseases are maternally inherited, i.e.
genome.wellcome.ac.uk /doc_wtd020740.html   (395 words)

  
 BioMed Central | Full text | The complete mitochondrial genome of the stomatopod crustacean Squilla mantis
Annotation of the mitochondrial genome of Squilla mantis.
The mitochondrial genome of Cherax destructor is considerably rearranged and evidences at least seven translocation events compared to the ancestral pancrustacean arrangement [20].
Negrisolo E, Minelli A, Valle G: The mitochondrial genome of the house centipede Scutigera and the monophyly versus paraphyly of myriapods.
www.biomedcentral.com /1471-2164/6/105   (3776 words)

  
 Mitochondrial genome - Wikipedia, the free encyclopedia
The mitochondrial genome is the genetic material of the mitochondria.
The genetic material forming the mitochondrial genome is similar in structure to that of the prokaryotic genetic material.
The mitochondrial chromosome is a circular DNA molecule, but unlike prokaryotes it is much smaller and several copies are present.
en.wikipedia.org /wiki/Mitochondrial_genome   (304 words)

  
 Mitochondrial genome definition - Medical Dictionary definitions of popular medical terms
Mitochondrial genome: All of the genetic information contained in the chromosome of the mitochondrion, a structure located in the cytoplasm outside the nucleus of the cell.
The mitochondrial genome consists of mitochondrial DNA (abbreviation: mtDNA).
Together, the mitochondrial genome and the nuclear chromosomal genome constitute the entire human genome.
www.medterms.com /script/main/art.asp?articlekey=4401   (0 words)

  
 Mitochondrion - Wikipedia, the free encyclopedia
This nonchromosomal DNA encodes a small number of mitochondrial peptides (13 in humans) that are integrated into the inner mitochondrial membrane, along with proteins encoded by genes that reside in the host cell's nucleus.
The enzymes of the citric acid cycle are located in the mitochondrial matrix with the exception of succinate dehydrogenase, which is bound to the inner mitochondrial membrane.
Mitochondrial ribosomes are the 70S (bacterial) type, in contrast to the 80S ribosomes found elsewhere in the cell.
en.wikipedia.org /wiki/Mitochondrion   (0 words)

  
 Plant Genome Organization and Structure : Mitochondrial Genome Organization
In comparison to the chloroplast genome, the size of the mitochondrial genome is quite variable.
Further, in comparison to the mitochondrial genomes of other species the size is quite large and variable.
The mitochondrial genome of corn undergoes the same type of recombination, but the events are more complex.
www.ndsu.nodak.edu /instruct/mcclean/plsc731/genome/genome8.htm   (513 words)

  
 Mitochondrial DNA Clarifies Human Evolution by Max Ingman
One possible reason for this is because these studies have focussed mainly on the polymorphisms in a small section of the mitochondrial genome called the D-loop, which comprises around 7% of the mitochondrial genome.
Although the mitochondrial genome is one of the first genomes to be sequenced in its entirety, it was not until recently that the progression of technology allowed sequences of that length to be obtained with relative ease and a study of any appreciable size using whole genomes was undertaken.
By determining the substitution rate of the genomic sequences, it is possible to derive dates for points on the tree and build a chronology of events in the evolution and migration of our species.
www.actionbioscience.org /evolution/ingman.html   (1599 words)

  
 The mitochondrial genome
The remaining mitochondrial OXPHOS proteins, the metabolic enzymes, the DNA and RNA polymerases, the ribosomal proteins and the mtDNA regulatory factors are all encoded by nuclear genes, synthesized in the cytosol and then imported into the organelle (Shoffner & Wallace 1995, Wallace
The human mitochondrial genome encodes 13 subunits of respiratory chain complexes: seven subunits (ND 1–6 and 4L) of complex I, cytochrome b (Cyt b) of complex III, the COX I–III subunits of cytochrome oxidase or complex IV, and the ATPase 6 and 8 subunits of F
At cell division, the mitochondria and their genomes are randomly distributed to the daughter cells, a process known as replicative segregation.
herkules.oulu.fi /isbn9514255674/html/x287.html   (1528 words)

  
 Endosymbiosis and The Origin of Eukaryotes
Both mitochondria and chloroplasts have their own genome and it resembles that of bacteria not that of the nuclear genome.
The genome of the chloroplasts found in Marchantia polymorpha (a liverwort, one of the Bryophyta) contains 121,024 base pairs in a closed circle.
The nucleomorph genome has given up all (but one) of its genes encoding enzymes for general metabolic functions; the endosymbiont now depends on those encoded by the host nucleus.
users.rcn.com /jkimball.ma.ultranet/BiologyPages/E/Endosymbiosis.html   (1388 words)

  
 UCSC Genome Browser: Best Links
The collection is primarily oriented toward human and mouse genomes.
To be included on this page, a tool must be web-oriented, allow free access with no registration barriers, be usable without installation or scripts, and be bioinformatic in nature.
Flybase -- database of drosophila genomics at Indiana
genome.ucsc.edu /bestlinks.html   (1391 words)

  
 Mitomap
A compendium of polymorphisms and mutations of the human mitochondrial DNA
Mitochondrial References (A-Z) or view only authors A-L or authors M-Z
If you have problems with the Mitomap website, please contact the webmaster:.
www.mitomap.org   (105 words)

  
 B. Franz Lang | FMGP
Longcore has further contributed organismal and ultrastructural information for these webpages.
The goals of FMGP are to (i) sequence complete mitochondrial genomes from all major fungal lineages, (ii) infer a robust fungal phylogeny, (iii) define the origin of the fungi, their protistan ancestors, and their specific phylogenetic link to the animals, (iv) investigate mitochondrial gene expression, introns, RNAse P RNA structures, mobile elements...
This project has been supported by the Medical Research Council of Canada (MRC)
megasun.bch.umontreal.ca /People/lang/FMGP/FMGP.html   (111 words)

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