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| | The mitochondrial genome |
 | | The remaining mitochondrial OXPHOS proteins, the metabolic enzymes, the DNA and RNA polymerases, the ribosomal proteins and the mtDNA regulatory factors are all encoded by nuclear genes, synthesized in the cytosol and then imported into the organelle (Shoffner & Wallace 1995, Wallace |
 | | The human mitochondrial genome encodes 13 subunits of respiratory chain complexes: seven subunits (ND 1–6 and 4L) of complex I, cytochrome b (Cyt b) of complex III, the COX I–III subunits of cytochrome oxidase or complex IV, and the ATPase 6 and 8 subunits of F |
 | | At cell division, the mitochondria and their genomes are randomly distributed to the daughter cells, a process known as replicative segregation. |
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