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Intra-operative Mitomycin C for glaucoma surgery Mitomycin C is a drug used during the initial stages of surgery to prevent the conjunctiva healing onto the sclera. Mitomycin C (MMC) is an antimetabolite used during the initial stages of a trabeculectomy to prevent excessive postoperative scarring and thus reduce the risk of failure. Mitomycin C appears to reduce the relative risk of failure of trabeculectomy both in eyes at high risk of failure (relative risk 0.32, 95% confidence interval 0.20 to 0.53) and those undergoing surgery for the first time (relative risk 0.29, 95% confidence interval 0.16 to 0.53). www.cochrane.org /reviews/en/ab002897.html   (484 words)

ACS :: Cancer Drug Guide: mitomycin Mitomycin belongs to a general group of chemotherapy drugs known as antibiotics but acts as an alkylating agent. Mitomycin blocks DNA synthesis in the cell, which results in cell death. Mitomycin is given by an injection in a vein over 20 minutes once every 6 to 8 weeks. www.cancer.org /docroot/CDG/content/CDG_mitomycin.asp   (797 words)

CIGNA - Mitomycin Mitomycin is an antitumor antibiotic used specifically in the treatment of cancer. Mitomycin slows or stops the growth and spread of cancer cells in the body. Mitomycin is administered only under the supervision of a doctor who is experienced in its use, such as a urologist or medical oncologist. www.cigna.com /healthinfo/tv6633.html   (551 words)

Mitomycin : Cancerbackup Mitomycin (pronounced my-toe-my-sin) is a chemotherapy drug that is given as a treatment for several different types of cancer, including breast, stomach, gullet (oesophagus) and bladder cancers. Mitomycin is a purple fluid after being dissolved from powder. When mitomycin is given into the bladder the side effects may be different to those mentioned here. www.cancerbackup.org.uk /Treatments/Chemotherapy/Individualdrugs/Mitomycin   (1157 words)

Mitomycin Facts Sheet Mitomycin is one of the older chemotherapy drugs, which has been around and in use for decades. Mitomycin is chemotherapy that is given as a treatment for some types of cancer (http://www.cancerbacup.org.uk/info/mitomycin.htm) Mitomycin is an Inhibitor of DNA synthesis and nuclear division. mitomycin.4mg.com   (274 words)

Complete Mitomycin information from Drugs.com Reconstitute 5 mg vial of mitomycin with 10 mL sterile water for injection for a concentration of 0.5 mg/mL. Diluted in various IV fluids at room temperature to a concentration of 20 to 40 mcg/mL, stability is as follows: 5% Dextrose Injection, 3 h; 0.9% NaCl Injection, 12 h; Sodium Lactate Injection, 24 h. The combination of mitomycin (5 to 15 mg) and heparin (1,000 to 10,000 units) in 30 mL of 0.9% NaCl Injection is stable for 48 h at room temperature. www.drugs.com /ppa/mitomycin.html   (942 words)

Consumer Reports Health - Mitomycin Mitomycin can cause a decrease in the number of blood cells in your bone marrow. Mitomycin is a type of antibiotic that is only used in cancer chemotherapy. Mitomycin is also used to treat adenocarcinoma of the colon and rectum; squamous cell carcinoma of the head and neck, lungs, and cervix; adenocarcinoma and duct cell carcinoma of the breast; and bladder cancer. www.consumerreports.org /mg/drug-reports/mitomycin.htm   (564 words)

Mitomycin – Mutamycin, Mitomycin-C, MTC – Chemotherapy Drugs - Chemo The mitomycin solution is injected into the catheter, which is then removed. The amount of mitomycin that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. The side effects of mitomycin and their severity depend on how much of the drug is given, and how it is given. www.chemocare.com /bio/mitomycin.asp   (1659 words)

RxMed: Pharmaceutical Information - MITOMYCIN FOR INJECTION USP Mitomycin is contraindicated for intravesical administration in patients who have demonstrated a hypersensitive or idiosyncratic reaction to it in the past. Mitomycin must be discontinued or dosage reduced upon evidence of abnormal depression of the bone marrow or the development of significant renal or pulmonary toxicity. Mitomycin has known teratogenic properties in animals, therefore, the benefits derived from the use of mitomycin in pregnancy must be weighed against the hazards involved. www.rxmed.com /b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20(General%20Monographs-%20M)/MITOMYCIN%20FOR%20INJECTION%20USP.html   (2092 words)

Mitomycin C   (Site not responding. Last check: ) Mitomycin has been used in a number of procedures to prevent scar formation in areas of ophthalmology (eye surgery). Mitomycin C is an antibiotic used in chemotherapy for certain cancer treatments. However, Mitomycin C is known to reduce collagen synthesis, which is the basis for scar formation. www.tracheostomy.com /surgery/mitomycin.htm   (267 words)

Mitomycin - Drugs & Vitamins - Drug Library - DrugDigest MITOMYCIN (Mutamycin®, Mitozytrex™) is a chemotherapy agent used for treating various types cancer, including stomach, pancreas, bladder, breast, or lung cancer. Mitomycin interferes with the growth of rapidly dividing cells, like cancer cells, and eventually causes these cells to die. Mitomycin may be used alone or with other chemotherapy agents or radiation therapy. www.drugdigest.org /DD/DVH/Uses/0,3915,460|Mitomycin,00.html   (852 words)

CiteULike: Trabeculectomy With Mitomycin C in Pseudophakic Patients With Open-angle Glaucoma: Outcomes and Risk Factors ... Trabeculectomy With Mitomycin C in Pseudophakic Patients With Open-angle Glaucoma: Outcomes and Risk Factors For Failure PurposeTo evaluate tonometric outcomes of trabeculectomy with mitomycin C in pseudophakic patients with open-angle glaucoma and associated risk factors for failure.DesignRetrospective cohort study.MethodsSeventy-three pseudophakic patients (89 eyes) with primary open-angle, normal-tension, exfoliative, or pigmentary glaucoma were recruited. Present findings indicate that trabeculectomy with mitomycin C provides acceptable long-term success rates in pseudophakic patients, with a low incidence of complications. www.citeulike.org /user/univ0509/article/888496   (289 words)

mitomycin Mitomycin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents. Mitomycin interferes with the growth of cancer cells and slows their growth and spread in the body. Mitomycin is used to treat cancer of the stomach and pancreas. www.ghc.org /kbase/topic.jhtml?docId=d00305a1&secId=d00305a1-Header   (1062 words)

Mitomycin Mitomycin is one of the older chemotherapy drugs, which has been around and in use for decades. Mitomycin is a purple color powder, or liquid, and is given by intravenous route only. Mitomycin is given by intravenous route once every six to eight weeks. www.tirgan.com /mitomyci.htm   (142 words)

Mutamycin (Mitomycin) drug description - prescription drugs and medications at RxList Mitomycin should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Mitomycin (also know as mitomycin-C) is an antibiotic isolated from the broth of Streptomyces caespitosus which has been shown to have antitumor activity. Mitomycin for Injection is a sterile dry mixture of mitomycin and mannitol, which when reconstituted with Sterile Water for Injection provides a solution for intravenous administration. www.rxlist.com /cgi/generic3/mitomycin.htm   (337 words)

Mitomycin Mitomycin is an antitumor antibiotic used specifically in the treatment of cancer. Mitomycin slows or stops the growth and spread of cancer cells in the body. Mitomycin is administered only under the supervision of a doctor who is experienced in its use, such as a urologist or medical oncologist. www.webmd.com /cancer/Mitomycin   (617 words)

mitomycin side effects   (Site not responding. Last check: ) Mitomycin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents. Mitomycin interferes with the growth of cancer cells and slows their growth and spread in the body. Mitomycin is used to treat cancer of the stomach and pancreas. www.medicationadvisor.com /side_effects/mitomycin.htm   (1199 words)

Mitomycin C Mitomycin C is a very old and established chemotherapy drug. Mitomycin C may have a harmful effect on a developing baby in the womb. While you are actually having the chemotherapy infusion mitomycin C may leak into the body tissue around the infusion vein and cause damage. www.cancerhelp.org.uk /help/default.asp?page=4012   (1245 words)

MITOMYCIN - INJECTION (Mutamycin) side effects, medical uses, and drug interactions. MITOMYCIN - INJECTION (Mutamycin) side effects, medical uses, and drug interactions. Notify your doctor immediately if you develop symptoms of an infection (such as persistent sore throat or fever), fatigue, easy bleeding or bruising, dark urine, or change in amount of urine. USES: Mitomycin is used to treat various types of cancer. www.medicinenet.com /mitomycin-injection/article.htm   (332 words)

BioMed Central | Full text | The optimal starting time of postoperative intraperitoneal mitomycin-C therapy with ... Noh SH, Yoo CH, Chung HC, Roh JK, Shin DW, Min JS: Early postoperative intraperitoneal chemotherapy with mitomycin C, 5-fluorouracil and cisplatin for advanced gastric cancer. Jansen M, Jansen PL, Fass J, Langejurgen E, Forsch S, Tietze L, Schumpelick V: Influence of intraperitoneal therapy with mitomycin C adsorbed on activated carbon on anastomotic and wound healing in rats. Wiznitzer T, Orda R, Bawnik JB, Rippin A, Griffel B, Herzberg M: Mitomycin and the healing of intestinal anastomosis. www.biomedcentral.com /1471-2407/5/31   (2832 words)

Mitomycin Mitomycin can decrease the number of white blood cells in your body, cells that usually help you fight infections. If mitomycin leaks out of the vein it is injected into, it can damage the tissue and cause scarring. Mitomycin may cause side effects that do not occur for months or years after you finish chemotherapy, including leukemia or decreased ability to have children. www.hci.utah.edu /patientdocs/hci/drugs/mitomycin.htm   (353 words)

UroToday - European Urology - Effect of Mitomycin C on Anterior Urethral Stricture Recurrence after Internal Urethrotomy Mitomycin C has antifibroblast and anticollagen properties and in sporadic reports of animal and clinical studies it has increased the success rate of trabeculectomy and myringotomy. This study evaluated the efficacy of mitomycin C in the prevention of anterior urethral stricture recurrence after internal urethrotomy. Mitomycin C (0.1mg) was injected submucosally at the urethrotomy site in 20 patients. www.urotoday.com /53/browse_categories/prostate_cancer/european_urology__effect_of_mitomycin_c_on_anterior_urethral_stricture_recurrence_after_internal_urethrotomy.html   (334 words)

Mitomycin (Systemic) - MayoClinic.com   (Site not responding. Last check: ) Although there is no specific information comparing use of mitomycin in children with use in other age groups, it is not expected to cause different side effects or problems in children than it does in adults. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. The dose of mitomycin will be different for different patients. www.mayoclinic.com /health/drug-information/DR202376   (1671 words)

Amazon.com: mitomycin   (Site not responding. Last check: ) Modulation of mitomycin C-induced sister chromatid exchanges and cell cycle delay by buthionine sulfoximine and reduced glutathione in mouse bone marrow... Intraoperative use of mitomycin C in fibrous atresia of the external auditory canal. Suppressing effects of S-methyl methanethiosulfonate and diphenyl disulfide on mitomycin C-induced somatic mutation and recombination in Drosophila melanogaster... www.amazon.com /s?ie=UTF8&keywords=mitomycin&index=blended&page=1   (527 words)

Mitomycin C aids corneal healing after photoablation - Ophthalmology Times Mitomycin C was applied during PRK/PTK to patients who developed haze after PRK and regression of the refractive effect. Six months after treatment with mitomycin C, grades 0 to 0.5 haze were seen in eight patients, and only one eye had grade 2 haze. Application of topical mitomycin C in patients who had undergone PRK prevents the development of corneal haze and improves the visual acuity without the occurrence of side effects. www.ophthalmologytimes.com /ophthalmologytimes/article/articleDetail.jsp?id=180495   (294 words)

Newswise Mitomycin C is a common chemotherapy agent that inhibits cell growth. Mitomycin C (MMC) is a common chemotherapy agent that inhibits cell growth. The authors of the study, “The Effects of Intradermal and Topical Mitomycin C on Wound Healing,” are Glen T. Porter, MD, and Swarupa Gadre, MD, of the University of Texas Medical Branch in Galveston, TX, and Karen Calhoun, MD Chair of University of Missouri Medical School. www.newswise.com /articles/view/507094   (948 words)

Formelsammlung Mitomycin   (Site not responding. Last check: ) Mitomycin ist ein Antibiotikum und wurde 1958 aus Streptomyces caesipitorus isoliert. Mitomycin Interkalation (Chemie) zwischen zwei Strängen der DNA. Nach intravenöser Gabe finden sich hohe Konzentrationen von Mitomycin in Niere, Muskel, Herz, Lunge, Zunge, Galle und Urin. www.formel-sammlung.de /wiki_Mitomycin.html   (227 words)

Methodist Healthcare - Cancer Information   (Site not responding. Last check: ) The overall response rate for the mitomycin regimen was 40% compared to 39% for the epirubicin regimen. These doctors concluded that a regimen of mitomycin, fluorouracil and cisplatin was as effective as a regimen of epirubicin, fluorouracil and cisplatin for the palliative treatment of patients with cancer of the esophagus or stomach but was associated with a reduction in hair loss. They thought that mitomycin cisplatin and fluorouracil should now be a standard treatment for patients with advanced cancer of the esophagus and stomach. www.methodisthealth.org /portal/site/methodist/menuitem.53adc36fdffffefe735f123111b18a0c/?&TierID=754&DocumentId=17632   (384 words)

Clinical Trial: Study With Mitomycin c/5-FU/FA in Pretreated Gastrointestinal Cancer Patients With Metastases (>= ... The aim of this study was to define the maximum tolerated dose (MTD) of bolus mitomycin C (MMC) in combination with 24 h-continuous infusion of 5-fluorouracil (FU) plus folinic acid, and to assess the toxicity and activity in patients with previously treated colorectal and gastric cancer. Escalating doses of MMC starting from 6 mg m(-2) in 2 mg m(-2)-steps to a maximum of 10 mg m(-2) were applied on days 1 and 22, given to fixed doses of 5-FU (2.600 mg m(-2)) as 24 h infusion and folinic acid 500 mg m(-2) prior to 5-FU weekly for 6 weeks Primary Outcomes: maximum tolerated dose (MTD) of bolus mitomycin C (MMC) in combination with 24 h-continuous infusion of 5-fluorouracil (FU) plus folinic acid; toxicity; activity www.clinicaltrials.gov /show/NCT00289445   (407 words)

Mitomycin C Kyowa - Mitomycin - Cancer Drug   (Site not responding. Last check: ) Mitomycin is used in the palliative management of cancers of head and neck, breast, lung (non-small cell carcinoma), stomach, pancreas, liver, colon, cervix, and bladder. Mitomycin should be administered intravenously (into a vein) to treat tumours other than bladder tumours. If disease progression continues to occur after two courses of Mitomycin C Kyowa, the medication should be discontinued, as further doses are unlikely to be beneficial. www.virtualcancercentre.com /drugs.asp?drugid=1734   (601 words)

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