| | International Union of Pure and Applied Chemistry |
 | | In spite of the ample use of Size Exclusion Chromatography (SEC) for measuring the molar mass distribution (MMD) of polymers, there are huge variations in the results obtained by different laboratories, when analyzing the same polymer sample. |
 | | Due to BB, the polydispersity is overestimated when calculated from a mass signal and a calibration curve, but is generally underestimated when obtained from the combined mass and "molar mass" signals. |
 | | Many approximate solutions have been proposed to overcome the classical deconvolution approach, e.g.: a) to assume simple analytical functions for the kernel and the mass chromatogram; b) to propose semi-empirical corrections based on the chromatogram shapes; and c) to modify the molar mass calibration rather than correcting the raw chromatograms. |
| www.iupac.org /projects/2003/2003-023-2-400.html (700 words) |