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Topic: Mononegavirales

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	Mononegavirales - Biocrawler (Site not responding. Last check: 2007-11-02)
		The Mononegavirales are an order of viruses comprising species that have a non-segmented, negative sense RNA genome.
		A number of important human diseases, both established (mumps, measles, rabies) and emerging (ebola haemorrahgic fever, borna disease, Hendra virus, Nipah virus), are caused by viruses from this order.
		RNA editing is a mechanism used by some members of Mononegavirales to produce multiple proteins gene.
	www.biocrawler.com /encyclopedia/Mononegavirales (562 words)

	Patent 6,777,220
		Since the Mononegavirales have not been observed to undergo homologous recombination, gene rearrangement is predicted to be irreversible, and therefore, the present invention provides a rational, alternative method for developing stably attenuated live vaccines against the non-segmented negative strand RNA viruses.
		For the mumps and parainfluenza viruses, the distal gene that encodes a surface glycoprotein is referred to as the HN (hemagglutinin/neuraminidase) gene.
		Representative examples of viruses of the order Mononegavirales are a Rhabdovirus, such as rabies virus or vesicular stomatitis virus, a Paramyxovirus, such as measles, mumps, parainfluenza virus or respiratory syncytial virus (human and bovine), or a Filovirus, such as Ebola virus or Marburg virus.
	www.pharmcast.com /Patents100/Yr2004/Aug2004/081704/6777220_RNA081704.htm (1586 words)

	MONONEGAVIRALES
		Specialty definitions using "MONONEGAVIRALES": Filoviridae &diams; Mononegavirales Infections &diams; Paramyxoviridae &diams; Rhabdoviridae.
		Raccoons continue to be the most frequently reported rabid wildlife species, and involved 37.7% of all animal-transmitted cases during the year 2000.
		Rabies virus belongs to the order Mononegavirales, viruses with a nonsegmented, negative-stranded RNA genome.
	www.websters-online-dictionary.org /definition/english/Mo/Mononegavirales.html (270 words)

	CRORA : RESUME DES PUBLICATIONS (Site not responding. Last check: 2007-11-02)
		We present a 8904-nt sequence of the central part of the RNA genome of a novel virus with a filovirus-like, nonidentical morphology named Taastrup Virus (TV) detected in the leafhopper Psammotettix alienus.
		Highly conserved domains were identified in the RNA-dependent RNA polymerase (L) between TV and other viruses within the order of Mononegavirales, and homology was found in particular with members of the Rhabdoviridae.
		The sequence similarities and the unique filovirus-like but nonidentical morphology unambiguously refer this newly identified virus to the order of Mononegavirales but to no family more than any to other within the order.
	www.pasteur.fr /recherche/banques/CRORA/res11/re6580.htm (206 words)

	Mononegavirales Terms and Definitions at www.MedicalGlossary.org
		Bornaviridae - A family in the order MONONEGAVIRALES comprising one genus Bornavirus.
		Paramyxoviridae - A family of spherical viruses, of the order MONONEGAVIRALES, somewhat larger than the orthomyxoviruses, and containing single-stranded RNA.
		Rhabdoviridae - A family of bullet-shaped viruses of the order MONONEGAVIRALES, infecting vertebrates, arthropods, protozoa, and plants.
	www.medicalglossary.org /rna_viruses_mononegavirales_definitions.html (243 words)

	Prof. Martin Billeter
		The basic features of the virion architecture, entry into host cells, replication and virion formation of all Mononegavirales, as far as elucidated on the molecular level, appear to be variations of a main strategy.
		Several general aspects of Mononegavirales replication transcription, such as promoter functions, intergenic transcription stop/restart signals, nature of the tight protein association to the genomic RNA in replicating and transcribing RNPs can now be tackled.
		On the other hand it might be possible to use MV and other Mononegavirales as small nonintegrating RNA vectors for cytotoxic gene therapy to eliminate cancerous or infected cells.
	www.molbio.unizh.ch /groups/previous/billeter/index.shtml (1431 words)

	ARS \| Publication request: OPEN READING FRAME III OF BORNA DISEASE VIRUS ENCODES A NONGLYCOSYLATED MATRIX PROTEIN (Site not responding. Last check: 2007-11-02)
		The etiological agent of BD, the Borna Disease Virus (BDV), is an enveloped virus characterized by a non-segmented negative strand RNA genome ethat belongs to the new family Bornaviridae within the order Mononegavirales.
		We examined the biochemical properties of BDV-M and found that it is a typical non-glycosylated matrix protein associated with the inner surface of the viral membrane, as is true for homologous proteins of other members of the Mononegavirales order.
		Our experimental data strongly suggest that p16 is a typical nonglycosylated matrix protein associated at the inner surface of the viral membrane, as is true for homologous proteins of other members of the Mononegavirales order.
	www.ars.usda.gov /research/publications/publications.htm?SEQ_NO_115=129417&pf=1 (394 words)

	BioMed Central \| Full text \| Evidence of recombination among early-vaccination era measles virus strains
		Recombination can allow variants of a population to escape from the current fitness peak (escape from Muller's ratchet) and re-appear with a new phenotypic make-up and/or even re-establish in a new host-relationship [7,8].
		However, recombination has never convincingly been documented in species of the Mononegavirales, and it is speculated whether this reflects an inability of these viruses to recombine.
		Yet, the order of Mononegavirales comprises groups of viruses with an apparently large evolutionary potential with frequent shifts of host species.
	www.biomedcentral.com /1471-2148/5/52 (4107 words)

	The Virus \| CDC Rabies
		Rabies virus belongs to the order Mononegavirales, viruses with a nonsegmented, negative-stranded RNA genomes.
		Within this group, viruses with a distinct "bullet" shape are classified in the Rhabdoviridae family, which includes at least three genera of animal viruses, Lyssavirus, Ephemerovirus, and Vesiculovirus.
		All information presented in these pages and all items available for download are for public use.
	www.cdc.gov /ncidod/dvrd/rabies/the_virus/virus.htm (752 words)

	[No title]
		The first is analytical and concentrated in, but not limited to, two distinct areas of sequence information, that of all Retroid agents, (the genetic agents that replicate or transpose themselves via an RNA intermediate (e.g., HIV); and the viral order Mononegavirales, (e.g., Ebola, Measles, Rabies).
		A subset of our collection of sequences from the viral order Mononegavirales, was recently used to address the evolution of single genes that encode multiple functions via RNA-editing and frame-shifting found among various lineages of the rhabdo- and paramyxo families (see Jordan, Sutter and McClure).
		We are also constructing HMMs representing the three proteins of the replication/transcription complex of the order Mononegavirales.
	www.homepage.montana.edu /~mmcclure/Research.html (953 words)

	RNA Polymerase II-Controlled Expression of Antigenomic RNA Enhances the Rescue Efficacies of Two Different Members of ...
		RNP of BDV is composed of viral full-length RNA associated with
		BDV is the only member of the Mononegavirales with a nuclear
		Functional hammerhead sequences are not required for the recovery of BDV and MV.
	jvi.asm.org /cgi/pmidlookup?view=long&pmid=16731909 (6007 words)

	Nebraska Center for Virology (Site not responding. Last check: 2007-11-02)
		Research in our laboratory is directed at understanding of the mechanisms of transcription and replication of RNA virus genomes.
		As models, we use vesicular stomatitis virus (VSV), a non-segmented negative-strand RNA virus in the order Mononegavirales, and the porcine reproductive and respiratory syndrome virus (PRRSV), in the order Nidovirales.
		For both of these viruses, we have established reverse genetic systems that are being used to address the role of sequences in the viral genome as well as the viral proteins encoded in the genome that regulate gene expression in these viruses.
	www.unl.edu /virologycenter/research/Pattnaik_Research.html (118 words)

	Sendai virus C proteins are categorically nonessential gene products but silencing their expression severely impairs ...
		It has not even been established whether or not the C proteins are essential for viral replication.
		Many other viruses in Mononegavirales encode C-like proteins, but their roles also remain to be defined.
		This study represents the first comprehensive functional assessment of the accessary C protein for Mononegavirales.
	www.genestocellsonline.org /cgi/content/abstract/3/2/111 (818 words)

	RNA Polymerase II-Controlled Expression of Antigenomic RNA Enhances the Rescue Efficacies of Two Different Members of ...
		RNA Polymerase II-Controlled Expression of Antigenomic RNA Enhances the Rescue Efficacies of Two Different Members of the Mononegavirales Independently of the Site of Viral Genome Replication -- Martin et al.
		RNA Polymerase II-Controlled Expression of Antigenomic RNA Enhances the Rescue Efficacies of Two Different Members of the Mononegavirales Independently of the Site of Viral Genome Replication
		measles virus (MV), a member of the Mononegavirales with a cytoplasmic
	jvi.asm.org /cgi/doi/10.1128/JVI.02389-05 (397 words)

	Health Virus Information \| Health > Mononegavirales > News (Site not responding. Last check: 2007-11-02)
		Health Virus and news and up to date information.
		Webmasters: Add this Health > Mononegavirales News to your web page for free using cut and paste RSS to JavaScript.
		We have no Health Mononegavirales News Stories at this time.
	www.healthvirusnews.com /health/mononegavirales/news/rss (48 words)

	Infections à Mononegavirales : sites et documents francophones
		Infections à Mononegavirales : sites et documents francophones
		Arborescence(s) du thesaurus MeSH contenant le mot-clé infections à Mononegavirales [mononegavirales infections] :
		Toute utilisation partielle ou totale de ce document doit mentionner la source.
	www.chu-rouen.fr /ssf/pathol/infectionsamononegavirales.html (41 words)

	Bornavirus
		Bornavirus, or Borna disease virus (BDV), infects a wide variety of vertebrates and belongs to the family Bornaviridae, part of the order Mononegavirales.
		Bornavirus particles are enveloped, spherical structures with a diameter of 100-130 nm.
		Search MEDLINE for the latest publications on this topic
	www-micro.msb.le.ac.uk /3035/Bornavirus.html (1250 words)

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