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| | EPA - Endocrine | Morbillivirus Infection In Bottlenose Dolphins |
 | | It has been postulated that anunderlying cause of these mass mortalities may be decreased levels of resistance toinfection, as a consequence of exposure to immunosuppressive environmental pollutants(e.g., PCB's, dioxins and furans, polyaromatic hydrocarbons and certain heavy metals). |
 | | Several approaches will be evaluated for estimation of pollutant levels, centeringon the ability of the most immunotoxic of these chemicals to bind to the aryl hydrocarbonreceptor (AhR). |
 | | References: de Swart, R.L., Harder, T.C., Ross, P.S., Vos, H.W. and Osterhaus, A.D.M.E. Morbilliviruses and Morbillivirus diseases of marine R.S., Kuehl, D.W., Stewart, J.L., Rhinehart, H.L. and Via, C.S. Decreased lymphocyte responses in free-ranging bottlenose dolphins (Tursiops truncatus)are associated with increased concentrations of PCBs and DDT in peripheral blood. |
| www.epa.gov /edrlupvx/inventory/ETD-LUB1.html (431 words) |
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