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Topic: Morris water maze


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In the News (Wed 23 Dec 09)

  
  WHFoods: Blueberries
Spanish researchers at the University of Barcelona found that after 8 weeks of feeding lab rats various blueberries, they saw a reversal of age-related declines in the rats' ability to find their way through the Morris water maze, a measure of the animals spatial learning ability and memory.
They gave old rats (aged 19 months) either a control or 2% blueberry diet for 8-10 weeks, tested them in the Morris water maze to check their spatial learning and memory, and then analyzed different brain regions for the presence of anthocyanins.
In the rats given the blueberry-containing diet, several anthocyanins were found in the cerebellum, cortex, hippocampus or striatum, but not in the controls— findings that are the first to show that blueberry's polyphenols can cross the blood brain barrier and localize in various brain regions important for learning and memory.
www.whfoods.com /genpage.php?tname=foodspice&dbid=8   (3177 words)

  
 Nat' Academies Press, New Horizons in Health: An Integrative Approach (2001)
Gülmezouglu M, de Onis M, Villar J. 1997 “Effectiveness of interventions to prevent or treat impaired fetal growth” Obstetric Gynecology Survey 52 : 139-149.
Kaminski N, Allard JD, Pittet JF, Zuo F, Griffiths MJD, Morris D, Huang X, Sheppard D, Heller RA.
Zaharia MD, Shanks N, Meaney MJ, Anisman H. 1996 “The effects of early postnatal stimulation on Morris water-maze acquisition in adult mice: Genetic and maternal factors” Psychopharmacology 128 :.
fermat.nap.edu /books/0309072964/html/63.html   (4369 words)

  
 McGill Centre for Studies in Aging
Champagne D., Rochford J. and Poirier J. (2000) ApoE and LDL receptor knockout mice display acquisition deficits in the Morris water maze.
(2002) Detailed analysis of learning strategies in three versions of the morris water maze task that differentially promote the use of allocentric and egocentric navigation in apolipoprotein E knockout mice.
R., Henderson, V., Panisset, M., Crystal H, Morris JC, Fillenbaum G, Heyman A and the CERAD Collaborators.) The relationship between extra-pyramidal signs and cognitive performance in patients with Alzheimer's disease enrolled in the CERAD Study.
www.aging.mcgill.ca /pub.htm   (8154 words)

  
 current graduate students
These include a Morris water maze, video tracking system for open field, automated radial arm mazes, swim stress apparatus, chambers for olfactory discrimination and memory, rodent operant chambers for training DM and DNM with retractable levers, avian operant chambers with video displays and touchscreens, serial reaction task chambers, and shuttle boxes.
We have tested the effects of stress and coping in this new paradigm on standard shuttle-escape learning as well as navigational learning and memory in a Morris water maze task.
Drugan, R. (2005) Intermittent cold water swim stress increases immobility and interferes with escape performance in rat.
www.unh.edu /psychology/grad_pro.htm   (10224 words)

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