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morula |
 | | The Drosophila morula (mr) gene, coding for APC2 subunit of the anaphase promoting complex/cyclosome, regulates variant cell cycles, because in addition to disrupting the archetypal cycle (G1-S-G2-M), mr mutations affect the rapid embryonic (S-M) divisions as well as the endo cycle (S-G) that produces polyploid cells. |
 | | The Drosophila morula (mr) gene is critical for the inactivation of mitotic functions throughout development in a variety of developmentally-modified cell cycles (Reed, 1997). |
 | | Morula protein is closely related to the APC2 subunit of the APC/C. APC2 contains a cullin domain, but Mr shows sequence conservation throughout the protein sequence, not solely within the cullin domain. |
| www.sdbonline.org /fly/newgene/morula1.htm (2437 words) |
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