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Topic: Mycoplasma genitalium

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Mycoplasma

Mycoplasma pneumoniae

Ureaplasma urealyticum

Saccharomyces cerevisiae

Nanobe

Pelagibacter ubique

Mimivirus

Urethritis

Model organism

Caenorhabditis elegans

Biological cell

Trichomonas vaginalis

Nanobacterium

Candida albicans

Nanoarchaeum

	Mycoplasma genitalium background (Site not responding. Last check: 2007-09-06)
		Mycoplasmas are members of the class Mollicutes and comprise a large group of bacteria which lack a cell wall, have small genomes, and a characteristically low G+ C content.
		Aside from their role as pathogens, mycoplasmas are of interest because they are believed to represent a minimal life form, having yielded to selective pressure to reduce genome size.
		genitalium genome is hindered by the difficulty in applying classical genetics to the study of this and other mycoplasmas, and the lack of available auxotrophic mutants due to the requirement of this organism for complex media for growth in culture.
	www.tigr.org /tdb/CMR/gmg/htmls/Background.html (377 words)

	Mycoplasma genitalium infections
		Mycoplasmas are difficult to study by classical genetic tools, both because of their fastidious growth requirements, and as a consequence of the absence of selectable markers.
		genitalium counterpart MgPa (ORF-2 or mgpB of the MgPa operon).
		genitalium was detected in nine (35%) of 26 specimens from the temporomandibular joint (188).
	www.danmedbul.dk /Dmb_2006/0106/0106-disputatser/DMB3770.htm (16719 words)

	Mycoplasma
		Cross-reactive anti-galactocerebroside antibodies and Mycoplasma pneumoniae infections in Guillain-Barre syndrome.
		Neurologic manifestations of Mycoplasma pneumoniae infections: diverse spectrum of diseases.
		Mycoplasma pneumoniae is a frequent cause of community-acquired respiratory infections in children and adults.
	www.thedoctorsdoctor.com /diseases/mycoplasma.htm (3561 words)

	mycoplasma (Site not responding. Last check: 2007-09-06)
		Mycoplasma genitalium is thought to have the smallest genome of any self-replicating organism, measuring only 580,070 bp long with just 470 open reading frames.
		Because it is essential for Mycoplasma to be able to bind to their host cells they have developed special tip organelles for this purpose, with a significant percentage of genes in their genome devoted to this important function.
		Mycoplasma may cause these various diseases, or it may be an opportunistic pathogen that colonizes a host with a weak immune system, and causes a secondary infection.
	biology.kenyon.edu /Microbial_Biorealm/bacteria/gram-positive/mycoplasma/mycoplasma.htm (1287 words)

	Azithromycin Failure in Mycoplasma genitalium Urethritis \| CDC EID
		Mycoplasma genitalium has been well described as a pathogen in men with acute and chronic nongonococcal urethritis (NGU) and has been associated with cervicitis in women (1).
		genitalium (13), herpes simplex viruses (HSV-1 and -2), Trichomonas vaginalis, Ureaplasma urealyticum and parvum, Gardnerella vaginalis, and adenoviruses (12).
		Association of Mycoplasma genitalium persistence in the urethra with recurrence of nongonococcal urethritis.
	www.cdc.gov /ncidod/eid/vol12no07/05-1558.htm (1996 words)

	Mycoplasma - MicrobeWiki
		Mycoplasma genitalium is thought to have the smallest genome of any self-replicating organism, measuring only 580,070 bp long with just 470 open reading frames.
		Because it is essential for Mycoplasma to be able to bind to their host cells they have developed special tip organelles for this purpose, with a significant percentage of genes in their genome devoted to this important function.
		Mycoplasma may cause these various diseases, or it may be an opportunistic pathogen that colonizes a host with a weak immune system, and causes a secondary infection.
	microbewiki.kenyon.edu /index.php/Mycoplasma (1336 words)

	IMMUNOSCIENCES LAB., INC. - News (Mycoplasma)
		Mycoplasma fermentans, M. pirum, M. hominis, and M. penetrans have been proposed as human pathogens and possible cofactors in HIV infection.
		Mycoplasma fermentans is considered to be a commensal in the human mucosal tissues and has often been found in saliva and oropharyngeal of 45% of healthy adults.
		In one study, it was suggested that pathogenic mycoplasma genomes were genetically manipulated, and part of the HIV genome was inserted into M. fermentans causing a large number of disease cases among veterans.
	www.immuno-sci-lab.com /mycoplas.html (1757 words)

	A novel polymerase chain reaction assay to detect Mycoplasma genitalium -- Eastick et al. 56 (1): 25 -- Molecular ...
		Use of the polymerase chain reaction for detection of Mycoplasma fermentans and Mycoplasma genitalium in the urogenital tract and amniotic fluid.
		Detection and discrimination of Mycoplasma pneumoniae and Mycoplasma genitalium by the in vitro DNA amplification.
		Mycoplasma pneumoniae and Mycoplasma genitalium mixture in synovial fluid isolate.
	mp.bmjjournals.com /cgi/content/full/56/1/25 (2349 words)

	Mycoplasma
		Although mycoplasmas are recognized primarily as extracellular parasites or pathogens of mucosal surfaces, recent evidence suggests that certain species may invade the host cells.
		Mycoplasma fermentans is capable of fusing with lymphocytes and changing their immunological characteristics.
		We believe that such long-term study about the efficacy of minocycline should be conducted on patients who are positive for mycoplasma and chlamydia genome (since we detect the chlamydia trachomatis genome in blood and joint fluid of 20% of patients with rheumatoid arthritis) and not by random selection of arthritis patients.
	www.immuno-sci-lab.com /html/mycoplasma.html (1706 words)

	More Information about Mycoplasma
		However, current explanations for the evolution of mycoplasmas argue for "degenerative" evolution from walled bacteria; thus the induction of L forms may be a present-day recapitulation of one step in mycoplasma evolution.
		If indeed mycoplasmas and the Lactobacillus group share a common ancestor, then it is likely that mycoplasma genomes evolved by "attrition" or "degenerative evolution" from an organism with a genome of about 2,200 to 2,500 kb (current sizes of genomes in the Lactobacillus group) (Maniloff, 1992).
		Mycoplasma pneumoniae is the leading cause of pneumonia in older children and young adults (Krause and Taylor-Robinson, 1992).
	globin.cse.psu.edu /globin/html/pip/more_myco.html (1903 words)

	Mycoplasma and Ureaplasma
		Due to the slow growth of mycoplasmas, the colonies may take up to 3 weeks to develop and are usually very small.
		Adherence factors - The mycoplasmas are extracellular pathogens that adhere to epithelial cell surfaces.
		Furthermore, the mycoplasmas have been shown to inhibit host cell catalase, thereby increasing the peroxide concentrations.
	pathmicro.med.sc.edu /mayer/myco.htm (1381 words)

	eMedicine - Ureaplasma Infection : Article by Ken B Waites, MD
		Mycoplasma hominis and Ureaplasma species, known collectively as the genital mycoplasmal organisms, are generally considered opportunists that cause invasive infections in susceptible populations.
		M genitalium is found in the lower urogenital tracts of men with urethritis and women with cervicitis and pelvic inflammatory disease.
		M genitalium is susceptible to macrolides, tetracyclines, and fluoroquinolones, but limited results from clinical studies suggest it may be very difficult to eradicate from the lower urogenital tract and no specific therapeutic recommendations are possible for this mycoplasmal species.
	www.emedicine.com /med/topic2340.htm (5440 words)

	Summary Mena et al. Mycoplasma genitalium infections in..Articles for review.Literature review.Sexually Transmitted ...
		Mycoplasma genitalium infections in asymptomatic men and men with urethritis attending a sexually transmitted diseases clinic in New Orleans.
		genitalium infection was defined as a positive test result for either the swab or the urine specimen.
		genitalium was detected in 8 (25%) of 32 men with urethritis and in 10 (7%) of 142 asymptomatic men (P =.006).
	www.who.int /std_diagnostics/literature_reviews/Issue_3/issue3_sum_Mena_16.htm (725 words)

	Mycoplasmas
		A good example of this is that a common mycoplasma found in the urogenital tract, Mycoplasma genitalium, was recently found in the lung and upper repiratory tract of patients suffering from a range of upper respiratory diseases including chronic asthma.
		Mycoplasma's tiny viral-like size and pleomorphism (The variation in the appearance of the nuclei of the same cell type.) facilitates their cell penetration but limits their synthetic capacity, thus requiring preformed maco moleules from another host cell for growth and reproduction.
		Mycoplasma pneumoniae is a frequent cause of exacerbation of bronchial asthma in adults.
	www.rain-tree.com /mycoresearch.htm (3635 words)

	Mycoplasma Testing
		Mycoplasma genitalium was also found and a very small percentage tested positive for Mycoplasma pneumoniae.
		In the case of Mycoplasma fermentans (incognitus), antibodies are not produced until the patient is near death.
		Mycoplasmas can become dormant from time to time, so if a patient is feeling well it might not be the best time to test.
	www.thepowerhour.com /news/mycoplasma_testing.htm (1510 words)

	The Subunit b of the F0F1-type ATPase of the Bacterium Mycoplasma pneumoniae Is a Lipoprotein -- Pyrowolakis et al. 273 ...
		The Subunit b of the F0F1-type ATPase of the Bacterium Mycoplasma pneumoniae Is a Lipoprotein -- Pyrowolakis et al.
		Mycoplasmas are not able to synthesize long-chain fatty acids by themselves (2, 12, 19).
		Mycoplasmas were grown for 12 h in the presence of 50 µg/ml globomycin; the proteins were separated by 12.5% SDS-PAGE, transferred onto a nitrocellulose membrane, and immunostained with subunit b-specific antiserum.
	www.jbc.org /cgi/content/full/273/38/24792 (2837 words)

	Disruption of gene mg218 of Mycoplasma genitalium through homologous recombination leads to an adherence-deficient ...
		the genomes of Mycoplasma genitalium (580 kb) and Mycoplasma pneumoniae
		the occurrence of homologous recombination in pathogenic mycoplasmas.
		genitalium, was unaffected by mutations in the hmw2 or crl locus
	www.pnas.org /cgi/content/full/96/9/5227 (5339 words)

	Antibiotic Susceptibility Testing of Mycoplasma genitalium by TaqMan 5' Nuclease Real-Time PCR -- Hamasuna et al. 49 ...
		genitalium DNA load was determined at 1, 2, and 3 weeks of incubation from the supernatant and from a mixture of supernatant and Vero cells scraped from the bottom of the same tubes.
		Mycoplasma genitalium in males with nongonococcal urethritis: prevalence and clinical efficacy of eradication.
		Mycoplasma pneumoniae and Mycoplasma genitalium mixture in synovial fluid isolate.
	aac.asm.org /cgi/content/full/49/12/4993 (3523 words)

	Characterization of MGC2, a Mycoplasma gallisepticum Cytadhesin with Homology to the Mycoplasma pneumoniae ...
		Characterization of MGC2, a Mycoplasma gallisepticum Cytadhesin with Homology to the Mycoplasma pneumoniae 30-Kilodalton Protein P30 and Mycoplasma genitalium P32
		Cross-hybridization between the cytadhesin genes of Mycoplasma pneumoniae and Mycoplasma genitalium and genomic DNA of Mycoplasma gallisepticum.
		Inhibition of Mycoplasma pneumoniae hemadsorption and adherence to respiratory epithelium by antibodies to a membrane protein.
	iai.asm.org /cgi/content/full/66/7/3436 (4015 words)

	Mycoplasma genitalium as a sexually transmitted infection: implications for screening, testing, and treatment -- Ross ...
		Use of TaqMan 5' nuclease real-time PCR for quantitative detection of Mycoplasma genitalium DNA in males with and without urethritis who were attendees at a sexually transmitted disease clinic.
		Detection of Mycoplasma genitalium in vaginal, cervical and urine specimens by TMA and PCR.
		Mycoplasma genitalium, herspes simplex viruses and adenoviruses in non-gonococcal urethritis.
	sti.bmj.com /cgi/content/full/82/4/269 (1783 words)

	GeneQuiz - Analysis of Mycoplasma genitalium genome (Site not responding. Last check: 2007-09-06)
		Mycoplasmas are the smallest known organisms capable of growth and reproduction outside living host cells.
		Like all mycoplasmas, M. genitalium lacks a cell wall, has a very small genome (M.
		genitalium in particular has the smallest genome of known cellular organisms capable of independent replication) and a low G+C content (32%).
	jura.ebi.ac.uk:8765 /ext-genequiz/genomes/mg (301 words)

	ipedia.com: Mycoplasma genitalium Article (Site not responding. Last check: 2007-09-06)
		Mycoplasma genitalium G-37 Scientific classification Kingdom : Bacteria Division: Firmicutes Class: Mollicutes Family: Mycoplasmataceae Genus : Mycoplasma Species : M. genitalium Strain: G-37 Mycoplas...
		Mycoplasm genitalium is a parasitic bacterium which lives in the primate genital and respiratory tracts.
		The genome of Mycoplasma genitalium consists of 580 kbp (kilo base pairs).
	www.ipedia.com /mycoplasma_genitalium.html (114 words)

	Defining the mycoplasma 'cytoskeleton': the protein composition of the Triton X-100 insoluble fraction of the bacterium ...
		Defining the mycoplasma 'cytoskeleton': the protein composition of the Triton X-100 insoluble fraction of the bacterium Mycoplasma pneumoniae determined by 2-D gel electrophoresis and mass spectrometry -- Regula et al.
		Neimark, H. Extraction of an actin-like protein from the prokaryote Mycoplasma pneumoniae.
		Proft, T., Hilbert, H., Layh-Schmitt, G. and Herrmann, R. The proline-rich P65 protein of Mycoplasma pneumoniae is a component of the Triton X-100-insoluble fraction and exhibits size polymorphism in the strains M129 and FH.
	mic.sgmjournals.org /cgi/content/full/147/4/1045 (5340 words)

	The Minimal Gene Complement of Mycoplasma genitalium -- Fraser et al. 270 (5235): 397 -- Science
		Mycoplasma genitalium P140 and P110 Cytadhesins Are Reciprocally Stabilized and Required for Cell Adhesion and Terminal-Organelle Development.
		Mycoplasma hyopneumoniae p65 Surface Lipoprotein Is a Lipolytic Enzyme with a Preference for Shorter-Chain Fatty Acids.
		Adhesion and inhibition assay of Mycoplasma genitalium and M. pneumoniae by immunofluorescence microscopy.
	www.sciencemag.org /cgi/content/abstract/270/5235/397 (2505 words)

	Interaction of Mycoplasmas With Host Cells -- Rottem 83 (2): 417 -- Physiological Reviews
		Mycoplasmas (class Mollicutes) are the smallest and simplest self-replicating bacteria (82).
		During the fusion process, mycoplasma components are delivered into the host cell and affect the normal functions of the cell.
		Mycoplasma nucleases able to induce internucleosomal DNA degradation in cultured cells possess many characteristics of eukaryotic apoptotic nucleases.
	physrev.physiology.org /cgi/content/full/83/2/417 (7754 words)

	Molecular cloning and characterization of an adherence-related operon of Mycoplasma genitalium -- Reddy et al. 177 ...
		Molecular cloning and characterization of an adherence-related operon of Mycoplasma genitalium -- Reddy et al.
		SVENSTRUP, H. Adhesion and inhibition assay of Mycoplasma genitalium and M. pneumoniae by immunofluorescence microscopy.
		Hnatow, L. L., Keeler, C. Jr., Tessmer, L. ymmek, K., Dohms, J. Characterization of MGC2, a Mycoplasma gallisepticum Cytadhesin with Homology to the Mycoplasma pneumoniae 30-Kilodalton Protein P30 and Mycoplasma genitalium P32.
	jb.asm.org /cgi/lookup?vol=177&fp=5943&view=abstract (465 words)

	Detection of Mycoplasma genitalium in urogenital specimens by real-time PCR and by conventional PCR assay -- Jurstrand ...
		Detection of Mycoplasma genitalium in urogenital specimens by real-time PCR and by conventional PCR assay -- Jurstrand et al.
		Detection of Mycoplasma genitalium in urogenital specimens by real-time PCR and by conventional PCR assay
		SSI-PCR is the conventional PCR at the Mycoplasma Laboratory at the Statens Serum Institut, Copenhagen, Denmark.
	jmm.sgmjournals.org /cgi/content/full/54/1/23 (3842 words)

	GeneQuiz - Analysis of Mycoplasma genitalium genome (Site not responding. Last check: 2007-09-06)
		Mycoplasmas are the smallest known organisms capable of growth and reproduction outside living host cells.
		Like all mycoplasmas, M. genitalium lacks a cell wall, has a very small genome (M.
		genitalium in particular has the smallest genome of known cellular organisms capable of independent replication) and a low G+C content (32%).
	columba.ebi.ac.uk:8765 /ext-genequiz/genomes/mg (301 words)

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