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	Transverse Myelitis: Symptoms, Causes and Diagnosis
		Joanne Lynn, M.D. Transverse myelitis (TM) is a neurologic syndrome caused by inflammation of the spinal cord.
		The term myelitis is a nonspecific term for inflammation of the spinal cord; transverse refers to involvement across one level of the spinal cord.
		"Acute transverse myelitis: incidence and etiological considerations." Neurology, 1981; 31:966.
	www.myelitis.org /tm.htm (1942 words)

	Transverse myelitis - Wikipedia, the free encyclopedia
		Transverse myelitis is a neurologic disorder caused by a loss of the myelin encasing the spinal cord, also known as demyelination.
		A major differentiation or distinction to be made is a similar condition due to compression of the spinal cord in the spinal canal, due to disease of the surrounding vertebral column.
		Unfortunately, the prognosis for significant recovery from acute transverse myelitis is poor in approximately 80% of the cases; that is, significant long-term disabilities will remain.
	en.wikipedia.org /wiki/Transverse_myelitis (932 words)

	MYELITIS - LoveToKnow Article on MYELITIS
		In the acute variety the nerve elements in the affected part become disintegrated and softened, but repair may take place; in the chronic form the change is slower, and the diseased area tends to become denser (sclerosed), the nerve-substance being replaced by connective tissue.
		Myelitis may affect any portion of the spinal cord, and its symptoms and progress will vary accordingly.
		The treatment for myelitis in its acute stage is similar to that for spinal meningitis.
	www.1911encyclopedia.org /M/MY/MYELITIS.htm (334 words)

	Myelitis
		Myelitis is a disorder of the spine marked by inflammation of the spinal cord.
		Myelitis is characterized by inflammation of segments of the spinal cord which can cause local back pain, usually followed by gradual spinal cord dysfunction.
		In Transverse Myelitis, congestion or obstruction of blood vessels, swelling, cellular infiltration or loss, and loss of the fatty tissue around the nerves (demyelination) may be seen on examining the involved segment of the spinal cord.
	hw.healthdialog.com /kbase/nord/nord462.htm (959 words)

	Myelitis - Wikipedia, the free encyclopedia
		Myelitis is a human disease involving swelling of the spinal cord, which disrupts central nervous system functions linking the brain and limbs.
		Symptoms include tingling, pain or loss of feeling, and may extend to weakness of the limbs and loss of bladder control.
		Untreated myelitis may rapidly lead to a permanently damaged spinal cord.
	en.wikipedia.org /wiki/Myelitis (80 words)

	Student Research Paper: Transverse Myelitis
		Transverse myelitis is a neurological disorder characterized by inflammation across both sides of one level, or segment, of the spinal cord.
		Myelitis in this respect refers to inflammation of the myelin of the spinal cord; transverse simply describes the position of the inflammation, that is, across the width of the spinal cord (Tabor 1999).
		From this wide array of symptoms, four classic features of transverse myelitis emerge that are essentially the symptoms used for diagnosis (particularly for idiopathic cases): (1) weakness of the legs and arms, (2) pain, (3) sensory alteration (dysaethesia), and (4) bowel and bladder dysfunction.
	www.is.wayne.edu /mnissani/SE/RossiTM.htm (20628 words)

	Genesis Health System - Detailed Disease Info - Transverse Myelitis (Site not responding. Last check: 2007-10-22)
		Transverse myelitis (TM) is an uncommon neurological syndrome caused by inflammation (a protective response which includes swelling, pain, heat, and redness) of the spinal cord, characterized by weakness, back pain, and bowel and bladder problems.
		Transverse myelitis has many different causes, often triggered by a variety of viral and bacterial infections (especially those associated with a rash such as measles or chickenpox).
		Other types of myelitis can be caused by poliovirus; herpes zoster; rabies, smallpox or polio vaccination; or parasitic and fungal infections.
	www.genesishealth.com /micromedex/detaileddisease/00068840.aspx (773 words)

	Transverse Myelitis Fact Sheet
		Transverse myelitis is a neurological disorder caused by inflammation across both sides of one level, or segment, of the spinal cord.
		The term myelitis refers to inflammation of the spinal cord; transverse simply describes the position of the inflammation, that is, across the width of the spinal cord.
		In patients with transverse myelitis, demyelination usually occurs at the thoracic level, causing problems with leg movement and bowel and bladder control, which require signals from the lower segments of the spinal cord.
	www.neuroanatomy.wisc.edu /selflearn/TransMyel.htm (2873 words)

	Baylor Neurology Case of the Month
		A rheumatologic cause of the patient's myelitis was strongly considered, as the patient had a highly elevated antinuclear antibody (ANA) titer, both on this presentation and at previous presentations.
		Myelitis is a rare complication, most commonly occurring in the immunocompromised patient (3).
		Devinsky et al, in their series of 13 patients with herpes zoster myelitis, found that the symptoms usually began unilaterally, or if bilateral, were asymmetric, with the motor and dorsal column functions altered to a greater degree on the side of the rash and spinothalamic functions altered contralaterally.
	www.bcm.edu /neurol/challeng/pat69/summary.html (2022 words)

	Transverse Myelitis Association
		Transverse Myelitis is a rare neurological disorder that is part of a spectrum of neuroimmunologic diseases of the central nervous system.
		The Transverse Myelitis Association was established in 1994 as an organization dedicated to advocacy for those who have these rare neuroimmunologic diseases.
		The Transverse Myelitis Association facilitates support and networking opportunities amongst families; provides educational information; functions as a clearinghouse for articles and research literature; and investigates, advocates for and supports research and innovative treatment efforts.
	www.myelitis.org (272 words)

	THE MERCK MANUAL--SECOND HOME EDITION, Acute Transverse Myelitis in Ch. 93, Spinal Cord Disorders
		The cause of acute transverse myelitis is unknown, but it may result from an autoimmune reaction (in which the immune system misinterprets the body's tissues as foreign and attacks them).
		Acute transverse myelitis must be distinguished from other disorders that cause similar symptoms, such as Guillain-Barré syndrome, spinal cord compression, or blockage of the blood supply to the spinal cord.
		In people with acute transverse myelitis, the number of certain types of white blood cells and the protein level in the spinal fluid are usually increased, but these findings are not conclusive.
	www.merck.com /mmhe/sec06/ch093/ch093h.html (398 words)

	Rapid onset transverse myelitis in adolescence: implications for pathogenesis and prognosis -- Wilmshurst et al. 80 ...
		Rapid onset transverse myelitis in adolescence: implications for pathogenesis and prognosis
		Transverse myelitis is a condition involving a spectrum of disease; the cause of paralysis should be questioned.
		myelitis is not a diagnosis, it is a condition of cord inflammation
	adc.bmjjournals.com /cgi/content/full/80/2/137 (2793 words)

	Transverse myelitis definition - Allergies: allergy symptoms, treatment, and medications by MedicineNet.com
		Transverse myelitis: A disease of the spinal cord in which there is demyelination (erosion of the myelin sheath that normally protects nerve fibers).
		Transverse myelitis can cause low back pain, spinal cord dysfunction, muscle spasms, a general feeling of discomfort, headache, loss of appetite, and numbness or tingling in the legs.
		Transverse myelitis may be caused by viral infections, spinal cord injuries, immune disorders (including systemic lupus erythematosus, Sjogren's syndrome, sarcoidosis and multiple sclerosis) or insufficient blood flow through the blood vessels in the spinal cord.
	www.medterms.com /script/main/art.asp?articlekey=11604 (486 words)

	Transverse myelitis & vaccines
		Fescharek R, et al (1995) Transverse myelitis unlikely to be due to measles, mumps, and rubella vaccine.
		Subsequent to a booster shot of anti-HBV recombinant vaccine, she developed regressive acute cervical transverse myelitis with intrathecal oligochonal IgG secretion and a hypersignal on the MRI T2 sequences of the cord.
		In the acute stage the appearance was an isolated myelitis of the conus medullaris with contrast enhancement.
	www.whale.to /vaccines/transverse.html (565 words)

	Transverse Myelitis
		Transverse myelitis is a demyelinating (loss of the fatty tissue around the nerves) disorder of the spinal cord.
		Transverse myelitis may be caused by viral infections, spinal cord injuries, immune reactions, or insufficient blood flow through the blood vessels in the spinal cord.
		It may also occur as a complication of such disorders as optic neuromyelitis, multiple sclerosis, smallpox, and measles, or as a complication of chickenpox vaccinations.
	healthlink.mcw.edu /article/921990579.html (222 words)

	Transverse Myelitis related information \| 180medical.com (Site not responding. Last check: 2007-10-22)
		Acute transverse myelitis (ATM) is a group of disorders characterized by focal inflammation of the spinal cord and resultant neural injury.
		It was proposed, therefore, that the myelitis was an "allergic" response to a virus rather than the virus itself that caused the spinal cord damage.
		It was in 1948 that the term "acute transverse myelitis" was utilized in reporting a case of fulminant inflammatory myelopathy complicating pneumonia [5].
	180medical.com /case_tm.asp (968 words)

	THE MERCK MANUAL, Sec. 14, Ch. 182, Spinal Cord Disorders
		Acute transverse myelitis must be differentiated from Guillain-Barré syndrome, anterior spinal artery occlusion, and acute cord compression, particularly that due to an epidural abscess, hematoma, or tumor.
		Treatable causes of acute transverse myelitis that should be considered are acute meningovascular syphilis, mycoplasmal infections, and multiple sclerosis.
		Corticosteroids have no proven benefit, except in myelitis secondary to multiple sclerosis, in which ACTH or corticosteroids may lead to regression of symptoms.
	www.merck.com /pubs/mmanual/section14/chapter182/182g.htm (305 words)

	Transverse Myelitis \| aHealthyAdvantage (Site not responding. Last check: 2007-10-22)
		Some toxic substances, such as carbon monoxide, lead, or arsenic, can cause a type of myelitis characterized by inflammation followed by hemorrhage or bleeding that destroys the entire circumference of the spinal cord.
		Medical history, physical examination, brain and spinal cord scans, myelogram, spinal tap, and blood tests are used to rule out other neurological causes of symptoms, such as a tumor.
		There is no effective treatment for transverse myelitis, but any underlying infection must be treated.
	www.ahealthyadvantage.com /topic/topic100587596 (828 words)

	IL-6 linked to transverse myelitis and multiple sclerosis
		Although the majority of transverse myelitis patients suffer a single attack, 15 percent to 30 percent of patients go on to develop full-blown multiple sclerosis.
		Transverse myelitis evolves rapidly and without warning and usually results in permanent impairment, including weakness of the legs and arms, bowel and bladder dysfunction, pain and paralysis.
		The benefit is, therefore, not only to those who are paralyzed by transverse myelitis, but to those who have disabilities due to a variety of autoimmune disorders.
	www.xagena.it /news/medicinenews_net_news/78f41579c50b633ec3c475380260fb61.html (597 words)

	Herpes zoster cervical myelitis in an immunocompetent subject. Mehndiratta MM, Bansal J, Gupta M, Puri V Neurol India
		Although HZ is characteristically benign, however, neurological complications are common and may range from transient pain and paraesthesias associated with the acute rash to post-herpetic neuralgia, segmental sensory loss or motor paresis, encephalitis, myelitis or cerebrovascular manifestations.
		In a large series,[2] the incidence of HZ myelopathy in individuals with compromised immunity has been reported to be around 0.8%.
		The average latent period between onset of rash and the appearance of myelitis is 8.5 days with a range of 5-10 days.
	www.neurologyindia.com /article.asp?issn=0028-3886;year=2000;volume=48;issue=2;spage=189;epage=90;aulast=Mehndiratta (854 words)

	Myelitis due to varicella-zoster virus in two patients with AIDS: successful treatment with acyclovir.
		Myelitis due to varicella-zoster virus in two patients with AIDS: successful treatment with acyclovir.
		Only a few cases of varicella-zoster virus (VZV) myelitis have been described, and nearly all have been diagnosed post-mortem.
		We conclude that (1) VZV should be considered a curable cause of myelitis in patients with AIDS, (2) PCR assay of CSF will assist in early diagnosis, and (3) early treatment with acyclovir should aid in recovery.
	www.aegis.com /aidsline/1997/jan/m9711064.html (402 words)

	Transverse Myelitis
		Transverse myelitis is a neurological disorder of the spine caused by inflammation across the spinal cord.
		However, transverse myelitis is a more specific term for inflammation (myelitis) across the width of the spinal cord (transverse) that results in changed function below this level while function remains normal above.
		Transverse myelitis is sometimes associated with other diseases, including systemic autoimmune diseases like systemic lupus erythematosis and sarcoidosis.
	www.webmd.com /hw/health_guide_atoz/nord462.asp (542 words)

	Search: Myelitis - Info.co.uk (Site not responding. Last check: 2007-10-22)
		myelitis (TM) is a neurologic syndrome caused by inflammation of the spinal...
		myelitis is a neurological disorder caused by inflammation across both sides of one level...
		myelitis is a neurological disorder of the spine caused by...
	dpxml.infospace.com /infocom.uk/results?otmpl=dog/webresults.htm&qkw=Myelitis&CMP=KNC-3LS480536328&infoad=1 (429 words)

	Johns Hopkins researchers discover key protein linked to transverse myelitis and multiple sclerosis
		Hopkins researchers have discovered a single molecule that is a cause of an autoimmune disease in the central nervous system, called transverse myelitis (TM), that is related to multiple sclerosis.
		Although the majority of TM patients suffer a single attack, 15 percent to 30 percent of patients go on to develop full-blown MS.
		We are actively using these findings to aid in developing future diagnostic, prognostic and therapeutic advancements," said Kerr, director of the Johns Hopkins Transverse Myelitis Center, the only center devoted to TM in the world.
	www.eurekalert.org /pub_releases/2005-09/jhmi-jhr092205.php (599 words)

	Bladder dysfunction in acute transverse myelitis: magnetic resonance imaging and neurophysiological and urodynamic ...
		Bladder dysfunction in acute transverse myelitis: magnetic resonance imaging and neurophysiological and urodynamic correlations -- Kalita et al.
		Bladder dysfunction in acute transverse myelitis: magnetic resonance imaging and neurophysiological and urodynamic correlations
		myelitis, whereas multiple sclerosis is a disease of white matter.
	jnnp.bmjjournals.com /cgi/content/full/73/2/154 (3152 words)

	Acute Schistosomiasis with Transverse Myelitis in American Students Returning from Kenya
		A diagnosis of transverse myelitis secondary to schistosomiasis was made when stool examinations showed ova of S. mansoni.
		Schistosomal transverse myelitis is rare and has been observed most frequently in infections with S. mansoni (3).
		Because of the potential benefit of the recommended therapy, presumptive treatment of patients with diagnoses of transverse myelitis and histories of water exposure in endemic areas should be initiated while awaiting results of parasitologic or serologic tests.
	www.cdc.gov /mmwr/preview/mmwrhtml/00000385.htm (1400 words)

	Partial Transverse Myelitis
		Usually with transverse myelitis, the symptoms are acute, meaning that they occur rapidly.
		To have one arm and leg would be very, very unlikely as the lesion would have to travel down only one side of the cord for several vertebrae.
		The CSF study would be telling, in ADEM inducing transverse myelitis I don't think you would see oligoclonal bands with increased MBP or Kappa chains.
	www.medhelp.org /perl6/neuro/messages/30226a.html (1163 words)

	Directory - Health: Conditions and Diseases: Neurological Disorders: Infections: Myelitis (Site not responding. Last check: 2007-10-22)
		Transverse Myelitis Association · iweb · cached · an organization dedicated to providing mutual support to families affected by Transverse Myelitis.
		Transverse Myelitis is an acute spinal cord inflammation involving both sides of the spinal cord.
		NINDS: Transverse Myelitis · cached · Information sheet compiled by the National Institute of Neurological Disorders and Stroke.
	www.incywincy.com /default?p=58565 (118 words)

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