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Myocyte calcification in acute MI In view of the deleterious effects of calcium on myocyte energy metabolism (13,14), we have postulated that the increase in myocardial calcium is a critical determinant of the deleterious effect of magnesium-deficient diets (15-17). AMI was defined as acute myocyte necrosis evidenced by loss of cross striations and nuclei, with or without the presence of contraction bands, and with or without an inflammatory reaction. That is, necrotic cardiac myocytes may become calcified, especially in patients who have a high serum calcium level or who are in uremia.(21,22). www.mgwater.com /geograph.shtml   (4096 words)

bcl-2 overexpression promotes myocyte proliferation -- Limana et al. 99 (9): 6257 -- Proceedings of the National ... It is noteworthy that connexin 43 was absent in the Myocyte volume of each cell class was similar in TG and WT at 24 days, but it increased in both groups at 2 months. Myocyte regeneration is a phenomenon that accompanies the normal development of the heart (8). www.pnas.org /cgi/content/full/99/9/6257   (4585 words)

Myocyte Death, Growth, and Regeneration in Cardiac Hypertrophy and Failure -- Nadal-Ginard et al. 92 (2): 139 -- ...   (Site not responding. Last check: 2007-10-21) Myocyte Death, Growth, and Regeneration in Cardiac Hypertrophy and Failure -- Nadal-Ginard et al. Myocyte nucleus in mitosis shows metaphase chromosomes visualized by the blue fluorescence of PI (B; arrowhead) and the cytoplasm by the red fluorescence of cardiac myosin antibody staining. The magnitude of myocyte replication that occurs in the overloaded circres.ahajournals.org /cgi/content/full/92/2/139   (7562 words)

Cardiac myocyte apoptosis provokes adverse cardiac remodeling in transgenic mice with targeted TNF overexpression -- ... prevalences of cardiac myocyte apoptosis in the MHCsTNF and Prevalence of cardiac myocyte apoptosis in the MHCsTNF mice within the endocardium, mid-wall, and epicardium at 4, 8, and 12 wk of age is indicated (J). myocyte apoptosis in the MHCsTNF mice from 4 to 12 wk, whereas ajpheart.physiology.org /cgi/content/full/287/3/H1303   (6221 words)

Direct Effects of Protamine Sulfate on Myocyte Contractile Processes : Cellular and Molecular Mechanisms -- Hird et al. ...   (Site not responding. Last check: 2007-10-21) Myocyte percent shortening (top), velocity of shortening (middle), and velocity of lengthening (bottom) significantly decreased from control values in the presence of both concentrations of protamine. Moreover, abundant fluorescein staining was readily observed throughout the interstitium and surrounding fascicles of myocytes. Specifically, myocytes maintained a rod shape, they were tolerant of extracellular Ca, the sarcomeres remained in register, and no alterations in sarcolemmal structure were observed. circ.ahajournals.org /cgi/content/full/92/9/433   (7378 words)

Reovirus Induction of and Sensitivity to Beta Interferon in Cardiac Myocyte Cultures Correlate with Induction of ... Primary cardiac myocyte cultures were infected at an MOI of 5 PFU per cell, and supernatants were removed at 10 and 20 h postinfection. Primary cardiac myocyte cultures were infected with three nonmyocarditic reoviruses or mock infected, and at 20 h postinfection RNA was harvested. Primary cardiac myocyte cultures were infected under three different conditions (duplicate wells for each data point) and lysed at the indicated times, and viral titers were determined by plaque assay. jvi.asm.org /cgi/content/full/72/2/1314   (5955 words)

A matter of life and death: cardiac myocyte apoptosis and regeneration -- Nadal-Ginard et al. 111 (10): 1457 -- Journal ... myocyte death and in the absence of myocyte hypertrophy, cardiac A thin layer of myocyte cytoplasm is recognized by the red fluorescence of cardiac myosin heavy chain. Myocyte death in the failing human heart is gender dependent. www.jci.org /cgi/content/full/111/10/1457   (2017 words)

Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility -- Kumar et al. ... and peak velocity of cardiac myocyte shortening and an increase Nitric oxide synthesis in rat cardiac myocytes and fibroblasts. Contractile responsiveness of ventricular myocytes to isoproterenol is regulated by induction of nitric oxide synthase activity in cardiac microvascular endothelial cells in heterotypic primary culture. ajpregu.physiology.org /cgi/content/full/276/1/R265   (5444 words)

Measuring Single Cardiac Myocyte Contractile Force via Moving a Magnetic Bead -- Yin et al. 88 (2): 1489 -- Biophysical ... In the numerical analysis, a cardiac myocyte is modeled as a was attached on one end of myocyte, as shown in Fig. Isolated myocyte contractile function is normal in postinfarction remodeled rat heart with systolic dysfunction. www.biophysj.org /cgi/content/full/88/2/1489   (2758 words)

Changes in myocardial cytoskeletal intermediate filaments and myocyte contractile dysfunction in dilated ... Changes in myocardial cytoskeletal intermediate filaments and myocyte contractile dysfunction in dilated cardiomyopathy: an in vivo study in humans -- Di Somma et al. Myocyte diameter was increased by 37% in the cardiomyopathy group compared with the controls (p < 0.002) (table 2). Improvement in cardiac myocyte function by biological effects of medical therapy: a new concept in the treatment of heart failure. heart.bmj.com /cgi/content/full/84/6/659   (5133 words)

Measuring Single Cardiac Myocyte Contractile Force via Moving a Magnetic Bead Biophysical Journal - Find Articles One of the biggest problems of heart failure is the heart's inability to effectively pump blood to meet the body's demands, which may be caused by disease-induced alterations in contraction properties (such as contractile force and Young's modulus). Thus, it is very important to measure contractile properties at single cardiac myocyte level that can lay the foundation for quantitatively understanding the mechanism of heart failure and understanding molecular alterations in diseased heart cells. In addition, attaching myocytes to the force transducer is also a challenging job (Tarr et al., 1983). www.findarticles.com /p/articles/mi_qa3938/is_200502/ai_n10298691   (692 words)

Myocyte Remodeling During the Progression to Failure in Rats With Hypertension -- Gerdes et al. 28 (4): 609 -- ...   (Site not responding. Last check: 2007-10-21) with a 23% increase in myocyte length and 18% increase in myocyte a proportional increase in myocyte dimensions because myocyte of a proportional increase in myocyte length and diameter. hyper.ahajournals.org /cgi/content/full/28/4/609   (4046 words)

The Cardiac Myocyte Page: the WorldWide Intensivist is released from the sarcoplasmic reticulum of the myocyte, and then re-absorbed to terminate contraction of the myocyte. Cardiac myocytes are packed with mitochondria, to provide the energy for the perhaps two billion heartbeats that will occur during a human lifespan. The ferocious utilization of energy by the myocyte is also reflected in the abundant capillaries coursing through the myocardium, and the large amount of myoglobin within heart muscle. www.anaesthetist.com /icu/organs/heart/myocyte.htm   (2376 words)

Poly(ADP-ribose) Polymerase-1-dependent Cardiac Myocyte Cell Death during Heart Failure Is Mediated by NAD+ Depletion ... Poly(ADP-ribose) Polymerase-1-dependent Cardiac Myocyte Cell Death during Heart Failure Is Mediated by NAD+ Depletion and Reduced Sir2{alpha} Deacetylase Activity -- Pillai et al. A, cardiac myocytes were treated overnight with MNNG either alone or together with NAD, and cell death was determined as described under "Materials and Methods." Values are means ± S.E. of four experiments. B, cardiac myocytes were transfected with different combination of plasmids (1.0 µg unless indicated otherwise) and/or treated with NAD as indicated. www.jbc.org /cgi/content/full/280/52/43121   (6359 words)

The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling -- Pare ... to mediate the induction of myocyte hypertrophy by the leukemia The nuclei of transfected, GFP-expressing myocytes (green) are indicated with arrowheads on the mAKAP panels. The nuclei of transfected, GFP-expressing myocytes (green) are marked with arrowheads on the mAKAP and myc panels. jcs.biologists.org /cgi/content/full/118/23/5637   (4735 words)

Ventricular Nonmyocytes Inhibit Doxorubicin-Induced Myocyte Apoptosis: Involvement of Endogenous Endothelin-1 as a ... Ventricular Nonmyocytes Inhibit Doxorubicin-Induced Myocyte Apoptosis: Involvement of Endogenous Endothelin-1 as a Paracrine Factor -- Tokudome et al. Ventricular Nonmyocytes Inhibit Doxorubicin-Induced Myocyte Apoptosis: Involvement of Endogenous Endothelin-1 as a Paracrine Factor -sarcomeric actin antibody as a marker for cardiac myocytes. endo.endojournals.org /cgi/content/full/145/5/2458   (4008 words)

CiteULike: Tag myocyte   (Site not responding. Last check: 2007-10-21) Spark-to-wave transition: saltatory transmission of calcium waves in cardiac myocytes. Mechanisms of sex differences in rat cardiac myocyte response to beta-adrenergic stimulation. ATP-sensitive K+ channels in rat ventricular myocytes are blocked and inactivated by internal divalent cations. www.citeulike.org /tag/myocyte   (285 words)

Inhibition of fibroblast proliferation in cardiac myocyte cultures by surface microtopography -- Boateng et al. 285 ... Inhibition of fibroblast proliferation in cardiac myocyte cultures by surface microtopography -- Boateng et al. in the proportion of myocytes on the pegged surfaces. A: Western blot of connexin43 (Cx43) from primary myocyte cultures grown on flat (lanes 1–3) or pegged membranes (lanes 4–6). ajpcell.physiology.org /cgi/content/full/285/1/C171   (5300 words)

Myocyte: The Beating Heart Cell You can dissolve an embryonic heart into its individual cell types with trypsin, an enzyme that destroys the protein glue between the cells. As long as the beating cells do not touch one another, their beats are independent - some are faster, some are slower. But after two or three days, the myocytes form interconnected sheets of cells (monolayers, shown right) that beat in unison. www.cellsalive.com /myocyte.htm   (257 words)

Biochemical markers of myocyte injury in heart failure -- Sato et al. 90 (10): 1110 -- Heart Biochemical markers of myocyte injury in heart failure -- Sato et al. of markers of myocyte injury may be a manifestation of ischaemic myocyte injury in patients with heart failure are few. heart.bmjjournals.com /cgi/content/full/90/10/1110   (3108 words)

Myocyte definition - Medical Dictionary definitions of popular medical terms Myocyte definition - Medical Dictionary definitions of popular medical terms Unbeknown to us, however, myocyte regeneration may accomplish just that." (Nature 415, 240, 2003) MedicineNet does not provide medical advice, diagnosis or treatment. www.medterms.com /script/main/art.asp?articlekey=19882   (81 words)

Medical Dictionary: Cardiac myocyte - WrongDiagnosis.com Cardiac myocyte : striated muscle cells found in the heart; derived from cardiac myoblasts and function in contracting the heart. Terms that may be interchangeable with Cardiac myocyte: Other terms that may be related to Cardiac myocyte: www.wrongdiagnosis.com /medical/cardiac_myocyte.htm   (192 words)

Cardiac myocyte definition - Medical Dictionary definitions of popular medical terms Cardiac myocyte definition - Medical Dictionary definitions of popular medical terms MedicineNet Home > MedTerms medical dictionary A-Z List > Cardiac myocyte Sometimes called a myocyte when it is understood that it is in the heart. www.medterms.com /script/main/art.asp?articlekey=23582   (64 words)

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