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Topic: NPM


  
  NPM - General Information
NPM was founded by a group of Salem, Oregon area physicians from a committee of the Marion-Polk County Medical Society.
NPM is controlled by a Board of Directors comprised of nine physician policyholders representing a broad base of medical specialties and geographical areas.
NPM insures over 2,300 physicians in Oregon, Idaho and Washington; it is the largest insurer of physicians in Oregon.
www.npmic.com /html/generalinformation.asp   (566 words)

  
 NPM statement   (Site not responding. Last check: 2007-10-24)
In 2000, NPM became a key participant and the largest contributor to a coalition to promote the passage of Ballot Measure 81.
In addition, the Company’s expense ratio was 26.7% for the year, which gave NPM a combined ratio of 221.0 for the year.
NPM’s CEO, Jim Dorigan is serving as a member of the Governor’s Task Force.
pages.zdnet.com /normcastillo/tortreform/id2.html   (1524 words)

  
 BLG 01-13 -Baylor Licensing Group - Baylor College of Medicine - Houston, Texas   (Site not responding. Last check: 2007-10-24)
NPM (nucleophosmin/B23, NO38 or Numatrin) is a major nucleolar phosphoprotein which is 20 times more abundant in cancer cells than in normal cells.
The human NPM gene was cloned and characterized recently, and it was found that the NPM gene is located on chromosome 5.
NPM serves as a cellular nucleolar marker and it aids in the determination of anti-cancer drug effect, apoptosis and detection of drug-resistant cells with the NPM-translocation assay.
www.bcm.edu /blg/techs/tech-01-13.html   (344 words)

  
 Wolfgang Drechsler, "The Rise and Demise of the New Public Management", Post-Autistic Economics Review, issue ...
NPM is the transfer of business and market principles and management techniques from the private into the public sector, symbiotic with and based on a neo-liberal understanding of state and economy.
NPM comes from Anglo-America, and it was strongly pushed by most of the International Finance Institutions (IFI’s) such as the World Bank and the IMF.
The economics-based problems of NPM were in fact quite predictable, partially because it is not based on genuine economics, so that, for example, quasi-markets were created within administrative organizations in order to create market behavior.
www.paecon.net /PAEReview/issue33/Drechsler33.htm   (4894 words)

  
 ARF Impedes NPM/B23 Shuttling in an Mdm2-Sensitive Tumor Suppressor Pathway -- Brady et al. 24 (21): 9327 -- Molecular ...
NPM and ARF proteins were immunoprecipitated with NRS, normal mouse serum (NMS), monoclonal antibody to NPM, or a rabbit polyclonal antibody directed to the ARF C terminus (ARF).
ARF colocalizes with NPM in the granular region of the nucleolus.
NPM and ARF proteins were immunoprecipitated (IP) with NRS, monoclonal antibody to NPM, or a polyclonal antibody directed to the ARF C terminus (ARF).
mcb.asm.org /cgi/content/full/24/21/9327   (6914 words)

  
 NPM: an entrepreneurial approach to government -DAWN - Business; October 1, 2001
The NPM has dominated public sector reforms in many OECD nations, requiring public organizations to shift their focus from “process towards purpose, reorganise their structures around programmes and strategy, adopt the financial and human resources management approaches of the private sector, and the de-bureaucratised forms of organization emerging there”.
Managerialism can be said to embrace an elevation of, and reliance on, the role of management where values of leadership, entrepreneurialism, strategy development and output orientation are practised within a frame-work of explicit goals and constraints set by the government which form the contractual obligations of the new public manager.
The NPM emphasises the need for new ways of solving governmental problems or creating opportunities, not as public activities in themselves, but by way of cooperation between public and private actors in concrete problems or situations presenting opportunities.
www.dawn.com /2001/10/01/ebr5.htm   (1687 words)

  
 Organic Cotton Beats Bt Cotton in India
A total of 121 NPM cotton farmers farming on 193 acres and using no synthetic pesticide were compared with 117 Bt cotton farmers using proprietary pesticides and farming 151 acres.
A majority of NPM farmers reported a medium incidence of pink bollworm, as did their Bt counterparts (47.1% against 57.3%), but greater numbers of NPM farmers also reported a low incidence of this pest compared to Bt farmers (31.4% against 24.8%).
The main strategy of NPM farmers' pest control on their crops is through beneficial insects that are, by definition, predators of cotton pests; they also use natural organic pesticides.
www.i-sis.org.uk /OCBBCI.php   (2141 words)

  
 BCM Pharmacology
NPM (Nucleophosmin/B23) is a major nucleolar protein that shuttles between nucleoli and cytoplasm.
However, dissociation of NPM from nucleoli to nucleoplasm and cytoplasm is observed after treatment with camptothecin (B).
Finch RA and Chan PK: (1996) ATP depletion affects NPM translocation and exportation of rRNA from nuclei.
www.bcm.edu /pharmacology/ch-p.htm   (815 words)

  
 NPM - Medical Professional Liability Insurance
NPM IS GOVERNED BY a board of actively practicing physicians.
NPM is a Physician owned company committed to providing a broad range of services to the medical community.
NPM has built its reputation on superior service and creative insurance solutions.
www.npmic.com /html/products/medmal.asp   (280 words)

  
 Bioreagents.com: Nucleophosmin
Nucleophosmin (NPM) also called B23, nutramin and NO38 is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53.
NPM continuously shuttles between the nucleus and cytoplasm.
Due to the NPM gene interaction with several tumor-associated chromosome translocations, NPM is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1.
www.bioreagents.com /index.cfm/fuseaction/products.detail/CatNbr/PA1-029   (271 words)

  
 NPM - CASA
The National Association of Pastoral Musicians (NPM) is a membership organization primarily composed of musicians, musician-liturgists, clergy, and other leaders of prayer devoted to serving the life and mission of the Church through fostering the art of musical liturgy in Roman Catholic worshipping communities in the United States of America.
National NPM members may apply their members' discount and receive considerable reductions in registration fees for all NPM schools, workshops and conventions.
One does NOT have to be a member of NPM to belong to NPM-CASA, although membership in NPM is encouraged.
www.sfasat.org /NPMCASA   (440 words)

  
 Nucleophosmin Is Required for DNA Integrity and p19Arf Protein Stability -- Colombo et al. 25 (20): 8874 -- Molecular ...
NPM is critical for the nucleolar localization and stability of Arf protein.
NPM binds histones and favors nucleosome assembly in vitro (26).
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma.
mcb.asm.org /cgi/content/full/25/20/8874   (5670 words)

  
 NissanPerformanceMag.com
NPM: Can you tell us a little about the import car scene in your home town.
NPM: Living in Japan must be like a kid in a candy store for a Japanese sports car lover, can you share some of your experiences as a Skyline owner in Japan?
I recall almost running a red light a few years back when I was passed by what appeared to be a lady in her mid 60's cruising along in a very nice R32 GTR!!!
www.nissanperformancemag.com /may03/skyline_gtv   (1371 words)

  
 Nucleophosmin (B23) Targets ARF to Nucleoli and Inhibits Its Function -- Korgaonkar et al. 25 (4): 1258 -- Molecular ...
Coincident detection of ARF (indicated by @) and associated human Mdm2 (Hdm2; #), NPM (**), and nucleolin (*) is denoted by symbols on the autoradiogram and Western blots.
P-labeled Narf6 cells by immunoprecipitation with ARF and NPM antibodies followed by Western blotting for nucleolin, as described for panel A. (C) Colocalization of ARF and NPM in Narf6 cells, indicated by their overlapping staining patterns (merge), was examined by confocal microscopy after immunofluorescent staining with antibodies to ARF and NPM.
Complexes between endogenous ARF and NPM in proliferating 10-1 cells (A) or in mouse NIH 3T3 fibroblasts infected with retroviruses encoding vector (lanes V) or ARF (lanes A) (B) were detected by reciprocal immunoprecipitation-Western blotting with ARF and NPM antibodies, as denoted.
mcb.asm.org /cgi/content/full/25/4/1258   (8401 words)

  
 UM-SSW: 6.0155: Nonprofit and Public Management (NPM) Center   (Site not responding. Last check: 2007-10-24)
The NPM Center is a collaboration of the University of Michigan Schools of Business, Public Policy, and Social Work.
NPM's research mission is to create a stimulating and supportive environment for faculty and graduate students with interests and expertise in the nonprofit and public sectors, through such vehicles as seminars, speakers, and conferences.
NPM is directed and was co-founded by Diane Kaplan Vinokur, Associate Professor of Social Work.
www.ssw.umich.edu /studentguide/2005/page.html?id=6.0155   (335 words)

  
 NPM Development in Taiwan—Bureaucracy and Democracy
Underlying NPM, the Central Government as well as local governments focus on "results" and "performance" in order to satisfy customers.
The NPM development in Taiwan can be obviously indicated from three aspects: contracting out services; electronic government; BOT (Build, Operate, Transfer) programs.
One of the important tensions discussed in NPM is the tension between bureaucracy and democracy.
www.inpuma.net /research/papers/sydney/yuyingkuo.html   (1659 words)

  
 Lymphomas Expressing ALK Fusion Protein(s) Other Than NPM-ALK -- Falini et al. 94 (10): 3509 -- Blood
was restricted to the cytoplasm and the N-terminus of NPM to the
The N-terminus of NPM (N-NPM) shows nucleus-restricted expression both in tumor cells (arrowhead) and in a normal endothelial cell (arrow), reflecting immunostaining of wild-type NPM (original magnification × 1,000).
Schematic illustration of the staining patterns for ALK and the N- and C-terminal portions of NPM in lymphomas carrying NPM-ALK or variant ALK fusion protein(s).
www.bloodjournal.org /cgi/content/full/94/10/3509   (4969 words)

  
 The Retinoic Acid Receptor {alpha} (RAR{alpha}) Chimeric Proteins PML-, PLZF-, NPM-, and NuMA-RAR{alpha} Have Distinct ...
(arrows), NPM was microspeckled in the nucleus and concentrated in large nucleolar bodies.
NPM localized normally to three to five nucleoli.
Chan P., Chan F. Nucleophosmin/B23 (NPM) oligomer is a major and stable entity in HeLa cells.
cgd.aacrjournals.org /cgi/content/full/13/4/173   (5534 words)

  
 The Academy of American Poets - National Poetry Month
Official NPM Logo: Download the official NPM logo and use it on your event programs, press releases, and websites.
Poster Gallery: Visit the NPM Gallery to view and buy copies of posters from previous years.
T-Shirt: With its David Sipress cartoon from The New Yorker, this t-shirt is perfect to wear during April.
www.poets.org /page.php/prmID/41   (540 words)

  
 China Outsourcing Services - Importing from China
NPM are the UK's leading China Outsourcing Company - We take the hassle out of importing goods from China
NPM are a UK based product and component part China outsourcing specialist.
NPM + SINOPH are here to make importing and outsourcing from China seem as straight forward as purchasing from a local supplier but with the added advantage of greatly increased profits.
www.networkproductmarketing.com   (268 words)

  
 Physical and Functional Interactions of the Arf Tumor Suppressor Protein with Nucleophosmin/B23 -- Bertwistle et al. 24 ...
NPM acidic and oligomerization domains are required for Arf binding in vivo.
Lower levels of p53 were detected in cells expressing NPM mutants C1 and C2 (lanes 20 and 22 versus 16), and this may explain the observed modest attenuation of Arf-induced proliferative arrest (Fig.
NIH 3T3 and MT-Arf cells transfected with NPM and mutants C1 and C2 were pulsed for 1 h with bromodeoxyuridine (BrdU), and incorporation of bromodeoxyuridine into S-phase cells was determined by immunofluorescence.
mcb.asm.org /cgi/content/full/24/3/985   (7705 words)

  
 NPM Bathrooms   (Site not responding. Last check: 2007-10-24)
With over 23 years experience specializing in bathrooms, we, the NPM team are committed to providing bathroom solutions.
From luxury steam cabins to the latest whirlpool bath technology, our showroom boasts a broad range of products designed to make your bathroom beautiful, as well as functional.
We at NPM pride ourselves on our impeccable customer service and superb efficiency, so come to us and make your ideal bathroom a reality.
www.npmbathrooms.com   (158 words)

  
 NationalPreludeMeet.com
SPS the Official Decal Sponsor of NPM 06!
NPM 2006 - Track Day by Erik Anderson Photography.
We'll be building on the strengths from the past 3 NPMs and create an event you won't soon forget.
www.nationalpreludemeet.com   (212 words)

  
 Retrovirus-Mediated Gene Transfer of NPM-ALK Causes Lymphoid Malignancy in Mice -- Kuefer et al. 90 (8): 2901 -- Blood
NPM is a highly conserved, ubiquitously expressed RNA-binding nucleolar phosphoprotein that includes among its functions the shuttling of ribonucleoproteins between the nucleolus and the cytoplasm to the ribosomes,
Analysis of various molecularly engineered NPM-ALK mutants using these in vitro transformation assays has shown that an intact NPM segment is absolutely required for NPM-ALK-mediated oncogenesis, because the NPM portion of the fusion protein provides an oligomerization motif that mediates NPM-ALK homodimerization, leading to intermolecular cross-phosphorylation and constitutive activation of the ALK phosphotransferase activity.
The 2; 5 translocation fuses the amino-terminal portion of NPM to the entire intracellular region of ALK, which includes the tyrosine kinase domain.
www.bloodjournal.org /cgi/content/full/90/8/2901   (7582 words)

  
 The Academy of American Poets - National Poetry Month FAQ
Posters: Each year the Academy creates and distributes nearly 200,000 official NPM posters, which are mailed for free to teachers, librarians, and booksellers nationwide.
Inspiration and Guidance: The Academy offers a plethora of practical resources for celebrating NPM, including tips for teaching poetry during April, creating a poetry book display in your bookstore or library, presenting a poetry reading or contest, and much more.
Please submit an event listing for your NPM program, and we will include it in our national events calendar.
www.poets.org /page.php/prmID/47   (1051 words)

  
 NPM SERVICES - Predictive Maintenance Specialist - Vibration Analysis
Vibration analysis in used to determine the operating condition of rotating equipment and to identify developing problems before they cause serious failures and unscheduled downtime.
By monitoring the wear cycle, machine components can be replaced before they fail during production runs.
The photo above shown an NPM Services technician taking a monthly reading from an electric motor at a Bowling Green, Kentucky manufacturer.
www.npm-services.com /wst_page4.html   (304 words)

  
 Molecular Biology of Anaplastic Lymphoma Kinase-Positive Anaplastic Large-Cell Lymphoma -- Kutok and Aster 20 (17): ...
A recombination event occurring with intron 4 of NPM and intron 16 of ALK gives rise to a NPM/ALK fusion gene, which is under the control of the ubiquitously active NPM promoter.
The N-terminal NPM domain mediates self-association, which dramatically increases autophosphorylation of multiple tyrosine residues within the ALK-derived portion of the fusion protein.
Ladanyi M, Cavalchire G: Detection of the NPM-ALK genomic rearrangement of Ki-1 lymphoma and isolation of the involved NPM and ALK introns.
www.jco.org /cgi/content/full/20/17/3691   (6383 words)

  
 A New Variant Anaplastic Lymphoma Kinase (ALK)-Fusion Protein (ATIC-ALK) in a Case of ALK-positive Anaplastic Large ...
in the NPM and ALK genes (10, 11).
Expression of ALK and NPM proteins in the patient’s lymph node biopsy.
An identical staining pattern (not shown) was observed for the COOH terminus of NPM (monoclonal antibody NPMc).
cancerres.aacrjournals.org /cgi/content/full/60/4/793   (4192 words)

  
 IBM Redbooks | Using Tivoli NetView Performance Monitor (NPM)
These additional new features and the existing management functions of NPM make it an outstanding management tool for today's heterogeneous network environment.
The focus of the redbook is to show how to efficiently implement and maintain this latest version of NPM with an emphasis on the new functions.
This redbook is intended to be used by OS/390 networking specialists who want to implement NPM 2.5.
www.redbooks.ibm.com /abstracts/sg245509.html   (165 words)

  
 Model of Inhibition of the NPM-ALK Kinase Activity by Herbimycin A -- Turturro et al. 8 (1): 240 -- Clinical Cancer ...
the NH terminus of the NPM fused to the cytoplasmic region
by NPM results in dysregulation of the kinase domain.
Bischoff D., Pulford K., Mason D. Y., Morris S. Role of the nucleophosmin (NPM) portion of the non-Hodgkin’s lymphoma associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis.
clincancerres.aacrjournals.org /cgi/content/full/8/1/240   (3778 words)

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