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Topic: NaKATPase

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Cell potential

Active transport

Cell (biology)

Action potential

Node of Ranvier

Synapse

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Ion channel

Jens Christian Skou

Electrochemical potential

Phosphorylation

Diffusion

Adenosine triphosphate

Adenosine diphosphate

Saltatory conduction

	847. Patulin (WHO Food Additives Series 35)
		injection of 5.0 or 7.5 mg/kg bw of patulin in male ICR mice, NaKATPase and MgATPase of liver, kidney and brain preparations were significantly inhibited.
		Patulin inhibited acetylcholinesterase and NaKATPase in cerebral hemisphere, cerebellum and medulla oblongata in rats treated for 1 month with i.p.
		Patulin inhibited acetylcholinesterase and NaKATPase in the cerebral hemisphere, cerebellum and medulla oblongata.
	www.inchem.org /documents/jecfa/jecmono/v35je16.htm (7948 words)

	Membrane potential - Wikipedia, the free encyclopedia
		Solar energy → converted to sugar by plants → converted by glycolysis to ATP → converted to concentration gradient by NaKATPase (sodium/potassium pump) → converted to voltage by passive K
		In most quantitative treatments of membrane potential, such as the derivation of Goldman equation, electroneutrality is assumed; that is, that there is no measurable charge excess in any side of the membrane.
		In a more formal notation, the membrane potential is the weighted average of each contributing ion's equilibrium potential.
	en.wikipedia.org /wiki/Membrane_potential (3136 words)

	NaKATPase Information Center - NaKATPase
		Another important task of the Na-K pump is to provide a Na gradient that is used by certain carrier processes.
		In the gut, for example, sodium is transported out of the resorbing cell on the blood side via the Na-K pump, whereas, on the resorbing side, the Na-Glucose co-transporter uses the created Na gradient as a source of energy to import both Na and Glucose, which is far more efficient NaKATPase than simple diffusion.
		Similar processes are located in the renal tubular system.
	www.scipeeps.com /Sci-Biochemistry_Topics_N_-_O/NaKATPase.html (588 words)

	Dalhousie Graduate Student Research Day (Site not responding. Last check: 2007-10-12)
		This increase was not reproduced by treatment with progesterone (10 nM, 24 hrs).
		We are currently examining the effects of estrogen on the expression of KCNQ1, KCNMA1, KCNH1, ENaC, CFTR and NaKATPase.
		Conclusions: Increases in KCNN4 mRNA expression may lead to increases in transepithelial potassium conductance, which may in turn be responsible for the higher level of potassium observed in milk compared to blood.
	research.medicine.dal.ca /graduate/posters/67.htm (253 words)

	689. Patulin (WHO Food Additives Series 26)
		The authors attributed this effect to reduced total ATPase, NaK ATPase, and alkaline phosphatase activities which were studied in a satellite group of rats (Devaraj et al., 1982a).
		injection of 5.0 or 7.5 mg/kg bw of patulin into male ICR mice, NaKATPase and MgATPase of liver, kidney and brain preparations were significantly inhibited.
		Patulin inhibited acetylcholinesterase and NaKATPase in cerebral hemisphere, cerebellum and medulla oblongata in rats treated for 1 month with approximately 1.6 mg/kg bw/day of patulin injected intraperitoneally.
	www.inchem.org /documents/jecfa/jecmono/v26je10.htm (4814 words)

	Study of the Electric Field Sensitivity of Yeast H+ ATPase - Research Information on the EMFRAPID Program (1994 -1998)
		While ultimately, we are interested in the effects of 60 Hz fields at amplitudes below a few mV/cm, it is essential to investigate the mechanism of interaction over a wide range of frequencies and amplitudes to establish a baseline understanding of how electric fields and cells may interact.
		Our specific hypothesis isthat the proton ATPase that we are studying will have similar field dependence to the related protein Sodium-Potassium ATPase (NaKATPase) for which both frequency and amplitude optima have been observed.
		The proton ATPase is a simpler system, and so a more exhaustive study than is possible with NaKATPase can be accomplished.
	www.niehs.nih.gov /emfrapid/extrmurabs/astumian.html (1280 words)

	art 13 (Site not responding. Last check: 2007-10-12)
		Hyperglycemia is an important oxidative stress that contributes to the elevated ROS in diabetes through increased polyol pathway activity.
		This in turn decreases NADPH, which results in alteration of the glutathione enzymatic system decreasing the NaKATPase leading to impairment of cellular function and endoneural hypoxia12.
		In non-diabetic rats, pro oxidant treatment caused a reduction in nerve blood flow, diminished endoneural oxygen tension, and abnormalities in nerve conduction velocity.
	www.aau-journal.net /art_13.htm (4140 words)

	MIchael Surace (Site not responding. Last check: 2007-10-12)
		He has taken responsibility for maintaining and preserving dozens human and animal of cell lines.
		He has spent time in development of a NaKATPase assay using para-Nitro Phenyl Phosphate.
		Recently, he has begun to support the NIH Program Project Grant under which he is employed as the cyclic AMP core for research labs at both UVA and Georgetown.
	marc.med.virginia.edu /people_michael.html (213 words)

	Ion pump Information - ion pump
		Such ion pumps, sometimes also known as ion transporters, can use energy from a variety of sources, including ATP or the concentration gradient of another ion (sometimes called an "ion exchanger").
		For a more detailed description of one particular kind of ion pump, see NaKATPase
		The field of electronics is the study and use of systems that operate by controlling the flow of electrons or other electrically charged particles in devices such as thermionic valves and semiconductors.
	www.inanot.com /Ina-Electronics_Topics_I_-_K-/Ion_pump.html (354 words)

	Acute Lung Injury and the Acute Respiratory Distress Syndrome: Four Decades of Inquiry into Pathogenesis and Rational ...
		The insert refers to ENaC, the epithelial sodium channel, which is a major pathway for the uptake of sodium on the apical surface of alveolar epithelial type I and II cells as well as distal airway epithelia.
		NaKATPase refers to the sodium pump located in the basolateral surface of alveolar and airway epithelia that actively pumps sodium into the interstitial space, thus creating a mini–osmotic gradient for the absorption of edema fluid from the alveolar.
		Both ENaC and NaKATPase can be upregulated by several catecholamine dependent and independent mechanisms.
	ajrcmb.atsjournals.org /cgi/content/full/33/4/319 (6598 words)

	Result Content View (Site not responding. Last check: 2007-10-12)
		In separate experiments O2 consumption by tubules was measured in a closed chamber.
		consumption paralleled the changes in NaKATPase activity indicated by
		increased oxidative phosphorylation, ATP concentration and NaKATPase activity at low pO
	www.abstracts2view.com /era/view.php?nu=ERA3L_383 (263 words)

	Cystinosis. A clinicopathological conference. 'From toddlers to twenties and beyond' Adult-Paediatric Nephrology ...
		Salmon RF, Baum M. Intracellular cystine loading inhibits transport in the rabbit proximal convoluted tubule.
		Coor C, Salmon RF, Quigley R, Marver D, Baum M. Role of adenosine triphosphate (ATP) and NaKATPase in the inhibition of proximal tubule transport with intracellular cystine loading.
		Effect of cystine loading and cystine dimethyl ester on renal brush border membrane transport.
	ndt.oxfordjournals.org /cgi/content/full/18/12/2492 (2274 words)

	FLUID AND ELECTROLYTE THERAPY (Site not responding. Last check: 2007-10-12)
		K diffuse out passively from cells, down the [K
		] gradient, and are pumped into cells by NaKATPase.
		During hypokalemia or hyperkalemia, the change in ECF[K
	myhome.hanafos.com /~ny2082/folder1/f&e.html (3164 words)

	[No title]
		List State Variables in order of appearance in IC.
		// //NaKATPase model adapted from code sent by J. Mailen Kootsey in Nov 2002 // Original description provided is: //"TITLE Guidotti 6-step scheme for Na,K transport //: Kootsey @ National Biomedical Simulation Resource, 12-29-89 //: Reference - J.B. Chapman, E.A. Johnson, and J.M. Kootsey, //: J. Memb.
		Note that this model is //: studied in steady-state only.
	nsr.bioeng.washington.edu /Courses/BIOEN589/06/lab/lab07/NaKpump3A589.proj (507 words)

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