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Topic: Narcolepsy

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	Narcolepsy - Wikipedia, the free encyclopedia
		Narcolepsy is a neurological condition most characterized by Excessive Daytime Sleepiness (EDS), episodes of sleep and disorder of REM or rapid eye movement sleep.
		Narcolepsy is strongly associated with HLA DQB1*0602 genotype.
		Narcolepsy is often mistaken for depression, epilepsy, or the side effects of medications.
	en.wikipedia.org /wiki/Narcolepsy (2539 words)

	Narcolepsy Fact Sheet: National Institute of Neurological Disorders and Stroke (NINDS)
		Narcolepsy is a chronic neurological disorder caused by the brain's inability to regulate sleep-wake cycles normally.
		Scientists studying narcolepsy in dogs have identified a mutation in a gene on chromosome 12 that appears to contribute to the disorder.
		Except in rare cases, narcolepsy in humans is not associated with mutations of the hypocretin gene.
	www.ninds.nih.gov /disorders/narcolepsy/detail_narcolepsy.htm (4086 words)

	Narcolepsy
		Narcolepsy is a sleep disorder associated with uncontrollable sleepiness and frequent daytime sleeping.
		Narcolepsy is characterized by episodes of frequent, uncontrollable daytime sleeping, usually preceded by drowsiness.
		Narcolepsy may also be associated with cataplexy, a brief episode of severe loss of tone of various muscles.
	www.umm.edu /ency/article/000802.htm (359 words)

	National Sleep Foundation
		Narcolepsy is a neurological disorder caused by the brain's inability to regulate sleep-wake cycles normally.
		Narcolepsy affects both sexes equally and develops with age; symptoms usually first develop in adolescence or young adulthood and may remain unrecognized as they gradually develop.
		Narcolepsy patients typically endure many years of daytime sleepiness before seeking treatment because sleepiness is not indicative of disease to most people.
	www.sleepfoundation.org /sleeptionary/index.php?id=12 (480 words)

	Home \| aHealthyme.com
		Narcolepsy is a disorder marked by excessive daytime sleepiness, uncontrollable sleep attacks, and cataplexy (a sudden loss of muscle tone, usually lasting up to half an hour).
		Narcolepsy is related to the deep, dreaming part of sleep known as rapid eye movement (REM) sleep.
		Narcolepsy is a complex disorder, and it is often misdiagnosed.
	www.ahealthyme.com /article/gale/100083745 (1004 words)

	[No title]
		Narcolepsy is a chronic, incurable central nervous system disorder characterized by excessive and overwhelming daytime sleepiness, frequent sleep attacks, cataplexy, and abnormal REM (rapid eye movement, a sleeping state in which dreaming occurs) latency.
		Narcolepsy can be difficult to diagnose since many of its symptoms often overlap or are very similar with clinical features of other disorders.
		Neurochemical and electrophysiological studies have shown that narcolepsy is associated with an abnormal cholinergic supersensitivity and a monoaminergic (dopamine and norepinephrine) hypoactivity.
	sulcus.berkeley.edu /mcb/165_001/papers/manuscripts/_267.html (2263 words)

	Narcolepsy
		Narcolepsy is a genetic disorder, but what causes narcolepsy is not yet known.
		A person with narcolepsy is likely to become drowsy or to fall asleep at inappropriate times and places, and sleep attacks may occur with or without warning.
		The goal of treatment of narcolepsy is for the patient to remain as alert as possible during the day and to minimize any recurring episodes of cataplexy, while using a minimal amount of medication.
	www.healthsystem.virginia.edu /uvahealth/adult_respire/narcolep.cfm (419 words)

	Scientific American: Feature Article: Narcolepsy: January 2000
		The overall incidence of narcolepsy in the U.S. is about 10 times that of amyotrophic lateral sclerosis (Lou Gehrig's disease), half that of multiple sclerosis, five times that of cystic fibrosis and about one quarter that of Parkinson's disease.
		For some reason, in narcolepsy a group of neurons that is supposed to be active only during REM sleep to suppress muscle tone and protect us from the elaborate motor programs that accompany our dreams is being triggered during waking [see box].
		The degeneration in the dogs was most pronounced in the amygdala, a brain structure known to be involved in emotion and in inducing sleep, and adjacent regions at the bottom of the forebrain.
	www.npi.ucla.edu /sleepresearch/sciam.htm (3596 words)

	Narcolepsy - Overview- SleepChannel
		Three additional symptoms are typically associated with narcolepsy: cataplexy (short-lived intermittent muscle weakness), hypnogogic and hypnopompic hallucinations (hallucinations while falling asleep or waking), and sleep paralysis (paralysis while falling asleep or waking).
		Narcolepsy usually begins when a person is in their teens or early twenties.
		Narcolepsy usually begins in the teens or early twenties (10 to 20 years old), but this varies; both young children and the elderly experience sleep attacks as well.
	www.sleepdisorderchannel.com /narcolepsy (223 words)

	Sleep Disorders: Narcolepsy from WebMD
		Narcolepsy is a neurological disorder that affects the control of sleep and wakefulness.
		Narcolepsy usually begins between the ages of 15 and 25, but it can become apparent at any age.
		The cause of narcolepsy is not known; however, scientists have made progress toward identifying genes strongly associated with the disorder.
	www.webmd.com /content/article/105/107670.htm (784 words)

	Narcolepsy, Sleep Paralysis, Hallucinations: Sleep Disorders: Merck Manual Home Edition
		Narcolepsy is a sleep disorder marked by recurring, uncontrollable episodes of sleep during normal waking hours, as well as by sudden episodes of muscle weakness (cataplexy), sleep paralysis, and hallucinations.
		Although narcolepsy has no serious medical consequences, it can be disabling and may increase the risk of motor vehicle and other accidents.
		People with narcolepsy are overcome by sudden episodes of uncontrollable sleepiness that can occur at any time.
	www.merck.com /mmhe/sec06/ch081/ch081d.html (496 words)

	Center for Narcolepsy - Stanford University School of Medicine
		Narcolepsy is a serious medical disorder and a key to understanding other sleep disorders.
		The Stanford Center for Narcolepsy was established in the 1980s as part of the Department of Psychiatry and Behavioral Sciences.
		The Stanford Center for Narcolepsy was the first to report that narcolepsy-cataplexy is caused by hypocretin (orexin) abnormalities in both animal models and humans (see FAQ and publications).
	med.stanford.edu /school/Psychiatry/narcolepsy/index.html (422 words)

	Narcolepsy
		Narcolepsy is chronic, which means signs and symptoms may vary in severity, but they never go away entirely.
		These low levels of hypocretin may even lead to the development of a diagnostic test for narcolepsy because hypocretin is normally present in spinal fluid of people without the disorder, but often isn't found in the spinal fluid of people with narcolepsy.
		Narcolepsy affects males and females equally and occurs in all racial and ethnic groups.
	www.cnn.com /HEALTH/library/DS/00345.html (2015 words)

	Narcolepsy Information Page: National Institute of Neurological Disorders and Stroke (NINDS)
		In addition to excessive daytime sleepiness (EDS), three other major symptoms frequently characterize narcolepsy: cataplexy, or the sudden loss of voluntary muscle tone; vivid hallucinations during sleep onset or upon awakening; and brief episodes of total paralysis at the beginning or end of sleep.
		It is likely that narcolepsy involves multiple factors interacting to cause neurological dysfunction and sleep disturbances.
		Among the most important common-sense measures people with narcolepsy can take to enhance sleep quality are actions such as maintaining a regular sleep schedule, and avoiding alcohol and caffeine-containing beverages before bedtime.
	www.ninds.nih.gov /health_and_medical/disorders/narcolep_doc.htm (640 words)

	eMedicine - Narcolepsy : Article by Matthew J Baker, MD (Site not responding. Last check: 2007-11-02)
		The term "narcolepsy" is derived from Greek, "seized by somnolence." Gelineau was the first to delineate the syndrome in 1880.
		Narcolepsy frequently is unrecognized, with a typical delay of 10 years between onset and diagnosis.
		Lin L, Faraco J, Li R, et al: The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene.
	www.emedicine.com /neuro/topic522.htm (3978 words)

	Facts About Narcolepsy - Frequently Asked Questions
		Narcolepsy is a chronic sleep disorder with no known cause.
		The symptoms of narcolepsy, especially the excessive daytime sleepiness and cataplexy, often become severe enough to cause serious disruptions in a person's social, personal, and professional lives and severely limit activities.
		Although it is estimated that narcolepsy afflicts as many as 200,000 Americans, fewer than 50,000 are diagnosed.
	www.talkaboutsleep.com /sleep-disorders/archives/Narcolepsy_FAQS.htm (1537 words)

	Narcolepsy - MayoClinic.com
		Narcolepsy is a chronic sleep disorder characterized by overwhelming daytime drowsiness and sudden attacks of sleep.
		People with narcolepsy often find it difficult to stay awake for long periods of time, regardless of the circumstances.
		Narcolepsy is a chronic condition that doesn't go away completely.
	www.mayoclinic.com /health/narcolepsy/DS00345 (213 words)

	Narcolepsy - WrongDiagnosis.com
		Narcolepsy is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Narcolepsy, or a subtype of Narcolepsy, affects less than 200,000 people in the US population.
		With a diagnosis of Narcolepsy, it is also important to consider whether there is an underlying condition causing Narcolepsy.
	www.wrongdiagnosis.com /n/narcolepsy/intro.htm (841 words)

	Narcolepsy
		Many patients with narcolepsy experience periodic limb movement disorder, also called PLMD (formerly known as nocturnal myoclonus), in which the leg muscles involuntarily contract every 20 to 40 seconds during sleep, occasionally arousing the patient, who, however, is usually unaware of the cause of the interruption.
		Narcolepsy patients with this genetic type tend to have a specific syndrome of symptoms that include cataplexy and periodic limb movement disorder.
		Certainly, patients with narcolepsy have emotional difficulties because of the condition and it is often difficult, particularly for a nonspecialist, to detect the physical problem.
	www.mercydesmoines.org /ADAM/WellConnected/articles/000098.asp (5547 words)

	Narcolepsy
		The symptoms of narcolepsy, especially the excessive daytime sleepiness and cataplexy, often become severe enough to cause serious disruptions in a person's social, personal, and professional life and can severely limit activities.
		Narcolepsy is an incurable life-long condition that requires continuous medication to reduce its symptoms.
		People with narcolepsy can lead productive lives if they are provided with proper medical care, avoiding when possible.
	www.planetpsych.com /zPsychology_101/Disorders/narcolepsy.htm (1345 words)

	Narcolepsy (Site not responding. Last check: 2007-11-02)
		The main characteristic of narcolepsy is excessive and overwhelming daytime sleepiness, even after adequate nighttime sleep.
		Although there is no cure for narcolepsy, treatment options are available to help reduce the various symptoms.
		Although there is not a cure for narcolepsy at present, several medications can help reduce its symptoms.
	www.stmarysmaine.com /other_health/diagnostics/narcolepsy.html (1432 words)

	Narcolepsy definition - Medical Dictionary definitions of popular medical terms
		Narcolepsy: A neurological disorder marked by a sudden recurrent uncontrollable compulsion to sleep.
		Narcolepsy is not a fatal disorder in itself but it can lead to fatalities.
		Narcolepsy is usually treated with a medication to improve alertness and an anti-depressant that helps control cataplexy.
	www.medterms.com /script/main/art.asp?articlekey=10471 (358 words)

	MedlinePlus Medical Encyclopedia: Narcolepsy
		The episodes usually occur after meals, but sudden onset of sleep may occur while working or driving a vehicle, having a conversation, or being in any sedentary or nonstimulating situation.
		Recently, patients with narcolepsy have been found to have low levels of hypocretin (a protein made by the brain) in their spinal fluid.
		It is not a fatal illness, but it may be dangerous if episodes occur during driving, operating machinery or similar activities.
	www.nlm.nih.gov /medlineplus/ency/article/000802.htm (807 words)

	Narcolepsy
		Narcolepsy is not a fatal disorder in itself.
		The registry's ultimate goal is to develop a better understanding of narcolepsy and to improve treatment by identifying the gene or genes associated with it.
		The Center staff are interested in helping all people with narcolepsy, particularly people who are newly diagnosed, so they can find better ways to cope with this disorder during the early stages of their treatment.
	www.stanford.edu /~dement/narco.html (1464 words)

	Narcolepsy Network, Inc.
		We are proud to have actor Isaiah Washington from the award-winning TV show “Grey’s Anatomy” serve as the spokesperson of our first-ever national campaign to raise awareness of narcolepsy.
		Washington lent his support to our cause after learning that a good friend and business colleague suffered from narcolepsy.
		Isaiah Washington, is featured in a series of three public service announcements aimed at raising awareness of narcolepsy.
	www.narcolepsynetwork.org (97 words)

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