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Topic: Nasal release

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nasal consonant

nasal cavities

bilabial nasal

velar nasal

alveolar nasal

dental nasal

palatal nasal

nasal vowel

labiodental nasal

inferior nasal concha

retroflex nasal

nasal bone

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		The early allergic response (2 to 5 minutes after antigen exposure) results from the release of these mediators and is characterized by sneezing, itching, and rhinorrhea.
		Nasal secretions appear to be primarily mediated by acetylcholine, whereas vasodilation is controlled by VIP.
		Reduction of edema at the osteomeatal complex is the goal of topical corticosteroid use in sinusitis but inhibition of the body's natural immune response to infection should preclude their use during an acute infection.
	www.utmb.edu /oto/Grand_Rounds_Earlier.dir/Nasal_Medications_1994.txt (3382 words)

	Effect of Organogel Components on In Vitro Nasal Delivery of Propranolol Hydrochloride
		The in vitro nasal release retardant effect of SMS and Tween 20 was investigated using factorial design.
		The nasal administration of nitroglycerin and melatonin as drops and sprays elicits the desired pharmacological response.
		The rectal release of salicylates, procaine, and ketoprofen from Eudragit-based organogels showed initial burst of drug release due to surface-deposited fraction of drug, and further release was governed by Eudragit concentration.
	www.aapspharmscitech.org /view.asp?art=pt050463&pdf=yes (3932 words)

	Nasal Spray
		Nasal spray is commonly used to alleviate nasal congestion, sinus infection, allergies, and other nasal problems.
		Xlear™ Nasal Wash is a patented, non-addictive nasal spray designed to aid in the relief and management of sinus infection caused by pollutants, allergens and infections of the nasal passages.
		It is the ONLY nasal wash that combines the unique properties of the natural substance, Xylitol, and the health-promoting practice of a saline nasal spray to help wash, hydrate and moisturize the nasal passages.
	www.xlear.com /articles/nasal-spray.aspx (521 words)

	eMedicine - Nonallergic Rhinitis : Article by Vijay R Ramakrishnan, MD (Site not responding. Last check: 2007-10-13)
		Nasal congestion and rhinorrhea are the chief manifesting symptoms of hormonal rhinitis.
		Nasal corticosteroids follow the same pathway of reducing inflammation as that of medications taken systemically, but their anti-inflammatory activity is localized to the upper airway.
		Nasal corticosteroids are believed to permit smooth-muscle relaxation, reduce airway hyperresponsiveness, and reduce the quantity and activity of inflammatory mediators.
	www.emedicine.com /ent/topic402.htm (5341 words)

	Nasals
		Some languages such as French and Portuguese have nasalized vowels as phonemes; although such vowels do exists in English as allophones of vowel phonemes in the presence of nasal consonants, the three nasals listed above are consonants which involve complete obstruction of the oral cavity.
		The location of the obstruction determines the place of articulation of the nasal: the lips for /m/, the tip or blade of the tongue at the alveolar ridge for /n/, and the back of the tongue at the velum for /N/.
		In addition to the resonances or poles which characterize the other sonorants, nasal sounds also have antiresonances or zeroes which affect the appearance of the formants in nasal phonemes.
	cslu.cse.ogi.edu /tutordemos/SpectrogramReading/cse551html/cse551/node35.html (548 words)

	Stop consonant at AllExperts
		In many languages, such as Malay and Vietnamese, final stops lack a release burst, or have a nasal release.
		Nasal stops are acoustically sonorants, as they have a non-turbulent airflow and are nearly always voiced, but they are articulatorily obstruents, as there is complete blockage of the oral cavity.
		This causes an audible nasal release, as in English sudden.
	en.allexperts.com /e/s/st/stop_consonant.htm (1054 words)

	Nasal Corticosteroids - Drug Comparisons - Compare Drugs - DrugDigest
		Nasal corticosteroids reduce swelling and secretions by decreasing the number of mediators (histamine and prostaglandins) in the nose.
		Nasal corticosteroids have been shown to improve symptoms of sneezing, itching of the nose, runny nose, and congestion.
		Nasal cytology in patients with allergic rhinitis: effects of intranasal fluticasone propionate.
	www.drugdigest.org /DD/Comparison/NewComparison/0,10621,51-1,00.html (1561 words)

	Cancer Information, Research, and Treatment for all Types of Cancer \| OncoLink
		An impaired sense of smell is a common complaint in patients with nasal polyposis, and hyposmia is usually attributed to obstruction of the nasal airways.
		Nasal lavages were performed prior to and after the last treatment and over 4 weeks, endoscopy and subjective scores at each weekly visit, and correspondent CT scans 4 weeks after the treatment.
		The primary nasal natural killer cell (NK/T cell) lymphoma is histologically characterized by angiocentricity with invasion of blood vessels and blockage of blood vessels by lymphoma cells, resulting in marked ischemic necrosis of the normal and neoplastic tissues.
	www.oncolink.upenn.edu /types/article.cfm?c=7&s=23&ss=184&id=7888 (6296 words)

	Sinusitis and Nasal Allergy
		Nasal saline may also be recommended to wash mucus from the nose.
		Decongestant or steroid nasal sprays may also be prescribed.
		Although the symptoms of sinusitis and nasal allergy may occur with a common cold, in general, cold-related symptoms subside within 1 week.
	www.clevelandclinic.org /health/health-info/docs/0700/0755.asp?index=6174 (573 words)

	NeilMed Products - Sinus Rinse, Nasal Rinse, Sinusitis, Rhinitis, Allergies - Francais
		Isotonic saline and HS (27 and 45 g x L(-1)), with and without concomitant histamine challenges, and with and without preceding methacholine challenges, were administered onto the nasal mucosa in 16 healthy subjects.
		The authors concluded that hypertonic saline alone evokes mucinous secretion in human nasal airways in vivo and that it also enhances the exudative and secretory effects of histamine and methacholine, respectively.
		It has been suggested that the mediator release observed on breathing cold and dry air is due to increased osmolality of airway secretions; the present data confirm that osmotic variations at the airway surface can provide an adequate stimulus for cell activation.
	www.nasalrinse.com /Fra/hypertonicirrigation.shtml (1229 words)

	Triamcinolone nasal Information on Healthline
		Triamcinolone nasal is used to treat the nasal symptoms of allergies and other seasonal reactions.
		The Nasacort brand of triamcinolone nasal is not approved for use by children younger than 6 years of age.
		The Tri-Nasal Spray brand of triamcinolone nasal is not approved for use by children younger than 12 years of age.
	www.healthline.com /multumcontent/triamcinolone-nasal (1223 words)

	fluticasone nasal
		Fluticasone nasal is used to treat the nasal symptoms of allergies and other seasonal reactions.
		Fluticasone nasal is not approved for use by children younger than 4 years of age.
		To prime the pump, hold the bottle with the nasal applicator pointing away from you and with your forefinger and middle finger on either side of the nasal applicator and your thumb underneath the bottle.
	hw.healthdialog.com /kbase/multum/d04283a1.htm (1425 words)

	The Dispatch - Serving the Lexington, NC - News
		Many use the term nasal continuant rather than nasal stop to refer to sounds like [1] and [2].
		Nasal stops are differentiated from oral stops only by a lowered velum that allows the air to escape through the nose during the occlusion.
		The duration between the release of the stop and the voice onset is called voice onset time (VOT).
	www.the-dispatch.com /apps/pbcs.dll/section?category=NEWS&template=wiki&text=plosive (1050 words)

	FDA Approves New Treatment for Allergies
		The Food and Drug Administration (FDA) announced today the approval of Omnaris (ciclesonide) nasal spray, a new drug for the treatment of nasal symptoms associated with seasonal and perennial allergic rhinitis, commonly known as hay fever, in adults and children 12 years of age and older.
		The ailment’s classic symptoms are watery nasal discharge, and fits of sneezing, and itching that can affect not just the nose but the roof of the mouth, throat and the Eustachian tubes which connect the middle ear to the back of the throat.
		The safety and efficacy of Omnaris nasal spray were studied in four randomized placebo controlled clinical trials ranging in duration from two weeks to a year.
	www.fda.gov /bbs/topics/NEWS/2006/NEW01495.html (279 words)

	RedOrbit - Health - Allergic Rhinitis: Proper Management Benefits Concomitant Diseases
		For example, in nonasthmatic individuals with seasonal AR, nasal allergen challenge caused an influx of eosinophils in both nasal and bronchial epithelium and lamina propria, demonstrating that nasal allergens produced a generalized airway inflammation that extended well beyond the nose.8 The reverse was also true.
		Nasal endoscopy can be used when needed to find nasal and sinus pathology, which might be missed by routine speculum and nasopharyngeal examination.1 Other components of examination in AR are eyes, oropharynx, ears, skin, and chest.
		Histamine is released within minutes of allergen exposure, mostly by mast cells, and mediates the early symptoms of AR: sneezing, itching, rhinorrhea, and to a lesser extent, congestion (see Table: "Mediators of the Early- and LatePhase Reactions in Allergic Rhinitis").
	www.redorbit.com /news/display/?id=117957 (4384 words)

	Leukotrienes in Rhinitis -- HOWARTH 161 (2): 133 -- American Journal of Respiratory and Critical Care Medicine
		It is thus evident that leukotrienes, released in concert with mucosal inflammation, contribute to rhinitis.
		The expression of leucocyte- endothelial adhesion molecules is increased in perennial allergic rhinitis.
		Indirect evidence of nasal inflammation assessed by titration of inflammatory mediators and enumeration of cells in nasal secretions of patients with chronic rhinitis.
	ajrccm.atsjournals.org /cgi/content/full/161/2/S1/S133 (2628 words)

	NeLH Medicine in the News Project; Nasal spray for obesity (Site not responding. Last check: 2007-10-13)
		As it was not possible to obtain the original research study and only limited data from the study were reported in the press release, it is not possible to comment on the quality of the research or the reliability of the findings.
		The objectives of this Phase 1 trial were to assess the safety, nasal tolerance and pharmacokinetics of PYY3-36 nasal spray as well as its effect on caloric reduction and initial indications of weight change.
		Participants were then randomised to receive one of six daily treatment schedules for the next six days, which included: three doses of nasal spray; two doses of nasal spray and one dose of placebo; and one dose of nasal spray and two doses of placebo.
	www.nelh.nhs.uk /hth/nasalspray.asp (673 words)

	Steroid-Induced Reduction of Histamine Release Does Not Alter the Clinical Nasal Response to Cold, Dry Air (CDA)
		Pre-treating nasal membranes with a nasal steroid for one week prior to a CDA challenge did not alter the nasal membrane response.
		Nasal lavages, to collect nasal secretions, were performed seven times at one minute intervals prior to the challenge and then twice, at ten and twenty minutes, post the CDA challenge.
		The significant reduction of histamine release by nasal steroids points towards an effect of these agents on the source of histamine, the mast cells.
	www.talkaboutsleep.com /sleep-disorders/archives/Snoring_apnea_humid_study10.htm (682 words)

	Nasal - Not another scripting language (Site not responding. Last check: 2007-10-13)
		Nasal is a language that I wrote for use in a personal project.
		Nasal 1.0, which fixed a long standing bug with break/continue inside foreach/forindex and a continue issue when used with multi-level labels, introduced a nasty regression with the regular old break statement.
		Nasal itself is now available as part of the SimGear package which provides utility code for the core simulator.
	www.plausible.org /nasal (827 words)

	Chitosan salts as nasal sustained delivery systems for peptidic drugs
		Vancomycin hydrochloride was used as a model peptidic drug, the nasal sustained release of which should avoid first-pass metabolism in the liver.
		This in-vitro study evaluated the influence of chitosan salts on the release behaviour of vancomycin hydrochloride from the physical mixtures at pH 5.5 and 7.4.
		In-vitro release of vancomycin was retarded by chitosan salts and, in particular, chitosan hydrochloride provided the lowest release of vancomycin.
	www.aapspharmaceutica.com /search/view.asp?ID=49655&size=small (172 words)

	Index of Balloon Peer Review Articles
		Patients with prior nasal or facial bone surgery, especially withmodification of the turbinates are not good candidates for nasal specificbecause the integrity of the structures is unpredictable.
		However, to my knowledge,the bilateral nasal specific technique, although not be any means the onlymethod of adjusting or manipulating cranial bones, is by far the most impactful.Indeed, due to the lack of research studies, this places it in the clinicalresearch field at best, and anecdotal research at least.
		The articlesuggests that nasal specific is one of the procedures that can help preventfuture episodes of otitis media, facilitate the healing process, decreasethe virulence of the pathogen, or increase the resistance of the patienthost.
	www.soto-usa.org /SOTLiterature/NCRT/AboutBACA.htm (2558 words)

	ENDO 99: Novartis Questions Relevance Of Merck's Osteoporosis Study (Site not responding. Last check: 2007-10-13)
		The results of the study sponsored by Merck were released at the annual meeting of The Endocrine Society in San Diego.
		According to the press release, Miacalcin Nasal Spray’s BMD results have been well documented and are included in the package insert.
		Since Miacalcin Nasal Spray has shown a significant impact on spinal fracture reduction with a relatively modest increase in BMD, a study to define the effects of Miacalcin Nasal Spray on bone quality and bone architecture and thereby determine Miacalcin Nasal Spray’s mechanism of action is underway.
	www.pslgroup.com /dg/107bb2.htm (1031 words)

	Institute of Phonetic Sciences,
		This is not because obstruents are specified as [–nasal] in these languages, but because they are specified for the perceptual feature [plosive] or [fricative], which means that a release burst or friction noise should be audible during these segments.
		This is relatively natural: under nasalization, a glide is still a glide, and a vowel is still a vowel, so that their main perceptual specifications are honoured in the output.
		Analogously to the situation in most other languages, where nasality can be seen as superposed on an oral string and implemented with a [lowered velum] gesture, these harmony systems may consider orality (in half of their morphemes) as being superposed on a nasal string and implemented with a [raised velum] gesture, i.e.
	www.fon.hum.uva.nl /Proceedings/Proceedings22/PaulBoersmaA/PaulBoersma1998a.html (6275 words)

	DelSite, News and Information, Press Release
		IVW 2006 is an international forum for world renowned experts in the field of influenza vaccines to report the latest data and trends associated with current and new influenza vaccines and their availability/delivery worldwide.
		Upon hydration by nasal fluid, the GelVac powder formulation changes from dry powder particles to wet gel particles, resulting in the formation of a gel that adheres to nasal mucus, thus maximizing antigen exposure through prolonged nasal residence time and sustained antigen release.
		GelVac is a proprietary nasal powder vaccine delivery system based on the GelSite® polymer, the primary functional ingredient that confers its unique in situ gelling property.
	www.delsite.com /newfiles/pr_061023.html (518 words)

	APStracts 6:0265A, 1999. (Site not responding. Last check: 2007-10-13)
		Temperature conditioning of nasal air: effects of vasoactive agents and involvement of nitric oxide.
		We hypothesized that nasal vascular tone and/or flow influences temperature conditioning of nasal air, and that NO participates in this process.
		We measured nasal air temperature (via a thermocouple) and exhaled nasal NO release (by chemilluminescence) in 5 humans and examined the effects of an aerosolized vasoconstrictor (oxymetazoline), a vasodilator (papaverine), NG -nitro-L-arginine methyl ester (L-NAME), an inhibitor of NO synthase, or saline (control).
	www.uth.tmc.edu /apstracts/1999/jap/June/265a.html (232 words)

	Schering-Plough - News and Media - News Releases
		CLARINEX-D 12 HOUR Extended Release Tablets should be administered when the antihistaminic properties of desloratadine and the nasal decongestant properties of pseudoephedrine are desired.
		CLARINEX Syrup (desloratadine) 0.5 mg per 1 mL, available in a bubblegum flavor, is approved for the relief of symptoms of outdoor allergies in children 2 years and older, and indoor allergies and hives of unknown cause in children as young as 6 months.
		Due to its pseudoephedrine component, CLARINEX-D 12 Hour Extended Release Tablets should not be taken by patients with narrow-angle glaucoma (abnormally high eye pressure), difficulty urinating, severe high blood pressure, or severe heart disease, or by patients who have taken a monoamine oxidase (MAO) inhibitor within the past fourteen (14) days.
	www.schering-plough.com /schering_plough/news/release.jsp?releaseID=811666 (1109 words)

	Nasal nitric oxide in man -- Lundberg and Weitzberg 54 (10): 947 -- Thorax
		Nasally derived NO has been shown to increase arterial oxygen tension and reduce pulmonary vascular resistance, thereby acting as an airborne messenger.
		Nasal nitric oxide is increased in patients with asthma and allergic rhinitis and may be modulated by nasal glucocorticosteroids.
		Nasal nitric oxide is increased in allergic rhinitis.
	thorax.bmj.com /cgi/content/full/54/10/947 (4356 words)

	Quercetin, Bromelain and Vitamin C: Natural Antihistamines for Allergy Support Article
		In allergic rhinitis, mast cells in the nasal area increase in number and are thought to play an important role in the nasal symptoms that occur during seasonal allergies.
		In one study, researchers triggered histamine release in nasal scrapings from seasonal allergy patients exposed to mite antigen.
		When the nasal scrapings were exposed to quercetin, histamine release was inhibited 46 percent to 96 percent.[1] In another study of rat mast cells exposed to an allergen, quercetin inhibited histamine release by 95 percent and 97 percent.[2]
	www.vrp.com /art/1704.asp (591 words)

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