| | IHC: Zomig (Zolmitriptan) Nasal Spray Offers Effective, Convenient Alternative For Migraine |
 | | Positron emission tomography (PET) imaging and pharmacokinetic profiling data suggest that up to 30 per cent of the administered dose of zolmitriptan nasal spray is absorbed directly across the nasal mucosa, with the remainder of the dose passing down the oesophagus and absorbed from the gastrointestinal tract. |
 | | A total of 1547 patients were randomized to one of four doses of zolmitriptan nasal spray (0.5 mg, 1.0 mg, 2.5 mg or 5.0 mg), zolmitriptan 2.5 mg oral tablet or placebo for the treatment of up to three moderate or severe migraine attacks. |
 | | All doses of zolmitriptan nasal spray were well tolerated with the majority of adverse events being of short duration, of mild or moderate intensity and resolved without medical intervention. |
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