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Topic: Natriuresis


In the News (Mon 6 Oct 08)

  
  Prevention of reflex natriuresis after acute unilateral nephrectomy by melanocortin receptor antagonists -- Ni et al. ...
The natriuresis was accompanied by an increase in
or oxytocin, is the mediator of the postnephrectomy natriuresis,
Intrathecal injection of an oxytocin-receptor antagonist attenuated postnephrectomy natriuresis in the male rat.
ajpregu.physiology.org /cgi/content/full/274/4/R931   (4399 words)

  
 CIPLADOC - Cardiology Update - Cardiology Publications - DytorHorizons
The lack of pronounced kaliuresis with torsemide is of potential clinical importance because the increased blood ammonia concentration induced by a diuretic in hepatic cirrhosis is related to the serum potassium concentration.
Natriuresis was also higher with torsemide than with frusemide and kaliuresis was similar in both groups.
Torsemide causes significantly greater diuresis, natriuresis, lesser kaliuresis, greater reduction in bodyweight and improvement in edema and ascites as compared to frusemide.
www.cipladoc.com /html/cardiology/publications/Dytor/DytorHorizons5.htm   (3165 words)

  
 Mechanism of vasopressin natriuresis in the dog: role of vasopressin receptors and prostaglandins -- ...
A possible PG mediation of AVP natriuresis in the dog was first suggested by Fejes-Toth and co-workers (17).
Natriuresis in conscious dogs caused by increased carotid [Na ] during angiotensin II and aldosterone blockade.
Vasopressin-induced natriuresis in the conscious rat: role of blood pressure, renal prostaglandin synthesis and the peptide ANF.
ajpregu.physiology.org /cgi/content/full/274/6/R1619   (3401 words)

  
 CNS-induced natriuresis, neurohypophyseal peptides and renal dopamine and noradrenaline excretion in prehypertensive ...
CNS-induced natriuresis, neurohypophyseal peptides and renal dopamine and noradrenaline excretion in prehypertensive salt-sensitive Dahl rats
The effect of dopamine receptor blockade on natriuresis is dependent on the degree of hypervolemia.
CNS-induce natriuresis is not mediated by the atrial natriuretic factor.
ep.physoc.org /cgi/content/full/90/6/847   (3605 words)

  
 Bradykinin may be involved in neuropeptide Y-induced diuresis, natriuresis, and calciuresis -- Bischoff et al. 275 (4): ...
NPY-induced elevations of diuresis, natriuresis, and calciuresis were similar in innervated and denervated kidneys.
natriuresis on intrarenal infusion in conscious and anesthetized
Neuropeptide Y-enhanced diuresis and natriuresis in anaesthetized rats is independent from renal blood flow reduction.
ajprenal.physiology.org /cgi/content/full/275/4/F502   (3562 words)

  
 PLASMA SODIUM CONCENTRATION PLAYS A SIGNIFICANT ROLE IN THE NATRIURESIS OF SODIUM LOADING IN NORMAL MAN. (via ...   (Site not responding. Last check: 2007-09-11)
The hypothesis that increases in the plasma concentration of sodium may induce natriuresis by a mechanism independent of changes in body fluid volume was tested in 6 seated subjects on a dietary sodium intake of 150 mmol NaCl/day.
The excess natriuresis following hypertonic saline infusion was not mediated by changes in arterial pressure since this parameter actually decreased slightly but significantly in the hypertonic series and remained unchanged following isotonic saline.
The mechanism of such osmostimulated natriuresis remains to be determined but appears independent of changes in arterial blood pressure and plasma concentrations of atrial natriuretic peptide.
www.lf2.cuni.cz.cob-web.org:8888 /physiolres/feps/andersen.htm   (334 words)

  
 The Meducator - Schemes for Problem Sovling - Hypertension
Such tumors are uncommon, but should be considered in patients with orthostatic blood pressure fall, present in about 60% of patients (vasculature is already maximally vasoconstricted, and volume status is low due to pressure natriuresis [see Note 1]), headaches, about 60% of patients, sweating, about 60% of patients, and palpitations, about 60% of patients.
If the contralateral kidney is normal, the systemic hypertension will cause "pressure natriuresis" in the unaffected kidney, thus compensating for the sodium retension in the affected kidney, and maintaining the volume status of the patient close to normal (or minimally expanded).
However, if the second kidney also has renal artery stenosis or the second kidney is missing, natriuresis does not occur, and renal sodium retention either in both kidneys or in the single existing kidney leads to volume expansion and evential suppression of renin and angiotensin II.
www.meducational.com /journal/april01issue/handbook/page12.html   (845 words)

  
 RemedyFind: patient ratings of Catapres etc. (Clonidine) for Hypertension (High Blood Pressure)   (Site not responding. Last check: 2007-09-11)
The maximal decrease in BP was seen 6 to 8 hours after drug administration and was similar to clonidine and nitroglycerin (-29+/-9 and -30+/-10 mm Hg, respectively), as was the average fall in BP throughout the night.
However, only clonidine effectively reduced nocturnal natriuresis (-0.09 mmol/mg Cr; 95% CI, -0.13 to -0.04; P=0.004), but this was not associated with improvement in morning orthostatic hypotension because of a residual hypotensive effect.
The decrease in BP induced by clonidine was modestly but significantly correlated with the magnitude of residual sympathetic tone determined in 10 subjects by the fall in BP induced by ganglionic blockade (r=0.66; P=0.043).
www.remedyfind.com /treatments/131/188   (1028 words)

  
 Treatment of heart failure till date has at best been symptomatic, with very little effort...   (Site not responding. Last check: 2007-09-11)
ANP is a 28 amino acid peptide stored predominantly in the right atrium and is believed to be released coupled to mechanoreceptors, which are stimulated on atrial distension, as observed in cardiac failure.
While a greater decrease in systolic blood pressure was documented with NEP inhibitors, the heart rate, diastolic blood pressure, and the functional class of the patients remained similar to baseline studies.
While the salutary effect of ACE-inhibitors in heart failure in general, and NEP inhibitors in changing adverse neurohormonal milieu per se remains unquestioned, efforts are in progress to develop a chimeric molecule combining both these properties23.
www.indegene.com /Car/FeatArt/indCarFeatArt22.html   (2606 words)

  
 Health News : Body Fat Reduces Ability to Control Blood Pressure   (Site not responding. Last check: 2007-09-11)
One key way that blood pressure is regulated is through the release of salt, or sodium chloride, in the urine, a process called natriuresis.
The findings, which appear in the American Journal of Hypertension, are based on a study of body composition and natriuresis in 127 African American and white subjects with an average age of 16 years.
As expected, stress was associated with an increase in blood pressure and natriuresis, the authors note.
www.keralanext.com /news/?id=910312   (288 words)

  
 British Journal of Pharmacology - Eukaliuric diuresis and natriuresis in response to the KATP channel blocker U37883A: ...   (Site not responding. Last check: 2007-09-11)
The observed eukaliuric diuresis and natriuresis in response to U37883A at 15 mg kg
In comparison, systemic application of furosemide elicited a diuresis and natriuresis which was accompanied by a substantial kaliuresis (see Figure 1c).
Confirming the observation that systemic application of U37883A elicits a diuresis and natriuresis, the present study further revealed that effects on water-permeable segments upstream to the distal tubule such as the proximal convoluted tubule contribute to this response.
www.nature.com /bjp/journal/v127/n8/full/0702742a.html   (5397 words)

  
 CIPLADOC - Cardiology Update - New Introductions - cipla
In liver cirrhosis, torsemide plus spironolactone combination causes significantly greater diuresis, natriuresis and free water clearance, with lesser patients requiring upward dose titration as compared to frusemide plus spironolactone combination.
Diurem (Metolazone) is a potent, long-acting thiazide-type diuretic indicated in edema associated with chronic renal disease, congestive heart failure (CHF) and in hypertension.
Metolazone causes significant diuresis and natriuresis primarily by inhibiting
www.cipladoc.com /html/cardiology/newintrocipla.htm   (2253 words)

  
 Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP -- Soares et al. 96 (1): 278 -- ...
the increasing OT-induced natriuresis preceded by 20 min the increasing
Because the natriuresis induced by the 10-fold higher dose of OT (10 µg) was only partially blocked by NAME and this dose
The natriuretic action of bradykinin also is caused by its release of NO followed by generation of cGMP (29).
www.pnas.org /cgi/content/full/96/1/278   (4681 words)

  
 Evaluated MEDLINE Multiple Records
These results indicate that the hypouricemia and hyperuricosuria of insulin-dependent diabetes mellitus is corrected by an adequate glycemic control, suggesting that these alterations are of a functional origin and due to a defective metabolic control.
L-NAME at 0.5 mg/kg caused a similar decrease in diuresis and natriuresis in control and hypothyroid rats, whereas no changes were seen in the hyperthyroid group.
These results indicate that pressure diuresis and natriuresis is accompanied by changes in RIHP and the response is modulated by the basal level of RIHP.
www.um.es /grupo-cirrosis/jgelphys.htm   (4682 words)

  
 Diuretic effect of hypoxia, hypocapnia, and hyperpnea in humans: relation to hormones and O2 chemosensitivity -- ...
Hypoxia itself appears to be the main stimulus of HDR, as demonstrated by Honig (13).
and natriuresis caused by 6 h of normobaric hypoxia are related
natriuresis induced by 3-6 h of hypoxia (9, 41).
jap.physiology.org /cgi/content/full/88/2/599   (6082 words)

  
 natriuresis - General Practice Notebook   (Site not responding. Last check: 2007-09-11)
Natriuresis is the excretion of sodium in urine, usually in excessive amounts.
The information provided herein should not be used for diagnosis or treatment of any medical condition.
Oxbridge Solutions Ltd® is an independent company owned by the authors which does not receive income from any other organisation or individual.
www.gpnotebook.co.uk /cache/-1939144645.htm   (79 words)

  
 APStracts 5:0120F, 1998.   (Site not responding. Last check: 2007-09-11)
Since this is seen upon systemic but not intrarenal NPY infusion, we have investigated the possible mediator of tubular NPY effects in anaesthetized rats.
The bradykinin B2 receptor antagonist, icatibant, accelerated the decline of the renovascular NPY effects with time; concomitantly it attenuated NPY-induced diuresis and natriuresis and abolished NPY -induced calciuresis.
We conclude that bradykinin may be involved in NPY -induced diuresis, natriuresis and in particular calciuresis.
www.uth.tmc.edu /apstracts/1998/renal/July/120F.html   (241 words)

  
 20-HETE and Furosemide-Induced Natriuresis in Salt-Sensitive Essential Hypertension -- Laffer et al. 41 (3): 703 -- ...
Furosemide significantly increased the natriuresis of both SS and SR patients, above that of the salt-replete period.
natriuresis in the intact SS animal or human, because the hypertensive
excretion during natriuresis produced by a salt load in SS patients.
hyper.ahajournals.org /cgi/content/full/41/3/703   (3358 words)

  
 Personal practice: Management of hyponatraemia in patients with acute cerebral insults -- Albanese et al. 85 (3): 246 ...
In patients with coexistent DI and CSW, it should be considered that natriuresis contributes to the increased urine output
Volume depletion and natriuresis in patients with a ruptured intracranial aneurysm.
CNS-induced natriuresis is not mediated by the atrial natriuretic factor.
adc.bmj.com /cgi/content/full/85/3/246   (2654 words)

  
 Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP -- Soares et al. 96 (1): 278 -- ...
Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP -- Soares et al.
Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP
Our hypothesis is that oxytocin (OT) causes natriuresis by activation of renal NO synthase that releases NO followed by cGMP
www.pnas.org /cgi/content/abstract/96/1/278   (501 words)

  
 Impairment of pressure-natriuresis and renal autoregulation in ANG II-infused hypertensive rats -- Wang et al. 279 (2): ...
Pressure natriuresis in salt-sensitive and salt-resistant sabra rats.
Influence of angiotensin II on pressure natriuresis and renal hemodynamics in volume-expanded rats.
Altered pressure natriuresis in chronic angiotensin II hypertension in rats.
ajprenal.physiology.org /cgi/content/full/279/2/F319   (4698 words)

  
 News & Reviews - DrugDigest
In a study of 276 healthy young adults, fl youths showed higher levels of microalbumin and lower levels of sodium in urine -- signs of possible kidney damage and high stress levels.
Researchers at the Medical College of Georgia in Augusta studied the link between "stress-induced pressure natriuresis" (SIPN) and levels of microalbumin (a marker of kidney function) in the urine between both white and fl adolescents.
"Stress-induced pressure natriuresis is related to microalbumin in African American youth," study author Dr. Coral Hanevold, associate professor of pediatrics, said in a prepared statement.
www.drugdigest.org /DD/Articles/News/0,10141,533455,00.html   (370 words)

  
 Renal Venous Doppler Sonography in Preeclampsia -- Bateman et al. 23 (12): 1607 -- Journal of Ultrasound in Medicine
a change in the pressure natriuresis response of the renal parenchyma.
It may be that a shift in the pressure natriuresis curve caused
with a shift in the pressure natriuresis curve.
www.jultrasoundmed.org /cgi/content/full/23/12/1607   (2039 words)

  
 IngentaConnect CNS-induced natriuresis, neurohypophyseal peptides and renal dopa...   (Site not responding. Last check: 2007-09-11)
To identify defects in the salt-sensitive Dahl rat (Dahl-S), the natriuretic, catecholaminergic and pressor responses to 60-min elevation of the cerebroventricular sodium concentration (CNS-induced natriuresis) were compared between prehypertensive salt-sensitive Dahl-S and salt-resistant Dahl rats (Dahl-R).
The plasma concentrations of the rat natriuretic hormone oxytocin, which has implications for the development of hypertension, and vasopressin (AVP) were also measured.
Dopamine is not a mediator of CNS-induced natriuresis in neither strain.
www.ingentaconnect.com /content/bsc/eph/2005/00000090/00000006/art00007   (282 words)

  
 Pharmacy Times: Excess Body Fat Hinders Blood Pressure Control
In the current study, reported recently in the American Journal of Hypertension, the amount of salt released in the urine fell as body fat rose.
The research involved an analysis of body composition and natriuresis in 127 African Americans and Caucasians with an average age of 16 years.
The results of the study showed that stress was connected with an increase in blood pressure and natriuresis.
www.pharmacytimes.com /article.cfm?ID=1986   (156 words)

  
 Role of Nitric Oxide on Papillary Blood Flow and Pressure Natriuresis -- Fenoy et al. 25 (3): 408 -- Hypertension
Role of Nitric Oxide on Papillary Blood Flow and Pressure Natriuresis -- Fenoy et al.
Blockade of pressure natriuresis induced by inhibition of renal synthesis of nitric oxide in dogs.
Role of renal interstitial pressure as a mediator of sodium retention during systemic blockade of nitric oxide.
hyper.ahajournals.org /cgi/content/full/25/3/408   (4903 words)

  
 Huang et al. 1996   (Site not responding. Last check: 2007-09-11)
Dehydration natriuresis in male rats is mediated by oxytocin.
of natriuresis induced by hypernatremia but not of that induced by
mmol/l) and natriuresis accompanied by an approximately 30%
www.hi.is /~ssa/rannsoknir/rottuheimildir/huang96.htm   (172 words)

  
 Chromosome 1 blood pressure QTL region influences renal function curve and salt sensitivity in SHR -- LO et al. 8 (1): ...
The pressure-diuresis and natriuresis curves were shifted to
and natriuresis were significantly lower than in WKY rats.
natriuresis together with a lower tubular sodium reabsorption.
physiolgenomics.physiology.org /cgi/content/full/8/1/15   (3446 words)

  
 Pressure Natriuresis in AT2 Receptor Deficient Mice with L-NAME Hypertension (via CobWeb/3.1 planetlab2.cs.unc.edu)   (Site not responding. Last check: 2007-09-11)
Pressure Natriuresis in AT2 Receptor Deficient Mice with L-NAME Hypertension
We previously reported that in AT2 receptor deficient mice pressure diuresis and natriuresis response (PDN) are blunted (Kidney Int 2000; 57:191-202).
In the present study, we examined the influence of L-NAME on blood pressure response and renal function in AT2 receptor deficient mice (AT2-/-) and controls (AT2+/+).
farm.rzpd.de.cob-web.org:8888 /ngfn/poster/model_orga/38gross3.html   (279 words)

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