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Topic: Neisseria gonorrhoeae


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In the News (Fri 27 Nov 09)

  
  Neisseria   (Site not responding. Last check: 2007-10-21)
Neisseria animalis; Neisseria bacilliformis; Neisseria canis; Neisseria cinerea; Neisseria dentrificans; Neisseria dentiae; Neisseria elongata; Neisseria flava; Neisseria flavescens; Neisseria gonorrhoeae; Neisseria iguanae; Neisseria lactamica; Neisseria macacae; Neisseria meningitidis; Neisseria mucosa; Neisseria perflava; Neisseria pharyngis; Neisseria polysaccharea; Neisseria sicca; Neisseria subflava; Neisseria weaveri; Neisseria sp.
Neisseria menigitidis is responsible for a large amount morbidity and mortality throughout the world with septicemia and meningitis cases estimated to be between 500,000 and 1 million every year (Dietrich et al.
Neisseria bacteria are responsible for the diseases meningitis and gonorrhoeae.
biology.kenyon.edu /Microbial_Biorealm/bacteria/proteobacteria/Neisseria/Neisseria.htm   (871 words)

  
 Neissera
Neisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues.
The bacterium Neisseria meningitidis, the meningococcus, is identical in its staining and morphological characteristics to Neisseria gonorrhoeae.
Neisseria meningitidis is usually cultivated in a peptone-blood base medium in a moist chamber containing 5-10% CO All media must be warmed to 37 degrees prior to inoculation as the organism is extremely susceptible to temperatures above or below 37 degrees.
textbookofbacteriology.net /neisseria.html   (5666 words)

  
 Neisseria gonorrhoeae Genome Sequencing - Strain FA 1090
Neisseria gonorrhoeae Genome Sequencing - Strain FA 1090
Because over 15% of the Neisseria gonorrhoeae genome contains dispursed repeated sequences, assembly by Phred/Phrap under high stringency requires that the unique sequences on either side of each repeat be determined independently by primer walking off large (4-8Kb) insert sub-clones and by binning the contigs based on known markers.
The GenBank accession number for the completed Neisseria Gonorrhoeae genome is AE004969 and this link gives the GenBank sequence file containing the sequence as deposited into GenBank.
www.genome.ou.edu /gono.html   (614 words)

  
 Neisseria gonorrhoeae   (Site not responding. Last check: 2007-10-21)
gonorrhoeae and will include not only traditional tests for the identification of this species but also discussions of rapid tests, problems associated with the tests, and the additional tests should be performed to identify a gram-negative, oxidase-positive diplococcal strain.
gonorrhoeae isolated" may ONLY be made when an isolate has been identified to the species level with sufficient tests to ensure the accuracy of the identification i.e., compensating for the problems associated with rapid tests.
gonorrhoeae are not, in themselves, sufficient for medicolegal purposes; isolates presumptively identified as N.
www.cdc.gov /ncidod/dastlr/gcdir/NeIdent/Ngon.html   (1332 words)

  
 Neisseria gonorrhoeae   (Site not responding. Last check: 2007-10-21)
Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of toll-like receptor 4-mediated signaling.
Intracellular survival of Neisseria gonorrhoeae in male urethral epithelial cells: importance of a hexaacyl lipid A. Infect Immun.
Accumulation of manganese in Neisseria gonorrhoeae correlates with resistance tooxidative killing by superoxide anion and is independent of superoxide dismutase activity.
hpv-web.lanl.gov /stdgen/bacteria/ngon/references.html   (2329 words)

  
 NEISSERIA   (Site not responding. Last check: 2007-10-21)
The Neisseria genus consists of aerobic, non-spore-forming Gram-negative coccobacilli which inhabit the mucous membranes of many animals (and humans).
An important means of identification of Neisseria species is the oxidase test, for which all members test positive.
gonorrhoeae is referred to as a gonococcal infection.
medic.med.uth.tmc.edu /path/00001510.htm   (417 words)

  
 Detection of neisseria gonorrhoeae - Patent 4332890
Lysates of the suspect organism are tested by reverse passive hemagglutination with particles sensitized with antibodies to eleven N. gonorrhoeae strains, ATCC 31397, 31398, 31399, 31400, 31401, 31402, 31403, 31404, 31405, 31406, and 31407.
An alternative commercial screening procedure involves the use of fluorescent antibodies and, while the procedure is relatively rapid and specific for all N. gonorrhoeae strains, the use of a rather expensive fluorescence microscope by a highly skilled technician is required for the determination.
Organisms suspected to be N. gonorrhoeae are removed from their growth medium and a suspension of organisms is prepared in water to a standard turbidity (as measured by optical density) and subsequently treated to develop a lysate test material.
www.freepatentsonline.com /4332890.html   (3541 words)

  
 Drug Resistant Strains Of Neisseria gonorrhoeae In Missouri And Hawaii
This report summarizes investigations of an increase in fluoroquinolone-resistant Neisseria gonorrhoeae in Hawaii and of a cluster of N.
gonorrhoeae infections with decreased susceptibility to azithromycin in Missouri.
gonorrhoeae to ciprofloxacin is used to assess susceptibility to all equivalent fluoroquinolone antimicrobials.
www.vidyya.com /archives/0922_3.htm   (1731 words)

  
 AEGiS-MMWR: Screening Tests To Detect Chlamydia trachomatis and Neisseria gonorrhoeae Infections --- 2002
gonorrhoeae isolation include a base medium supplemented with chocolatized equine or bovine blood to support the growth of the gonococcus; selective media differ from routine culture media in that they contain antimicrobial agents (i.e., vancomycin, colistin, and an antifungal agent), which inhibit the growth of other bacteria and fungi.
gonorrhoeae with urine or vaginal swab specimens is suboptimal.
gonorrhoeae at a local laboratory, the isolate should be sent to a reference laboratory (e.g., a city, county, or state public health laboratory) for confirmation, chiefly in cases of alleged sexual assault or rape.
www.aegis.com /pubs/MMWR/2002/RR5115-1.html   (15600 words)

  
 Molecular Epidemiology of Neisseria gonorrhoeae: Sequence Analysis of the porB Gene Confirms Presence of Two ...
Genetic diversity and mosaicism at the por locus of Neisseria gonorrhoeae.
Serological classification of Neisseria gonorrhoeae with monoclonal antibodies.
Topology of outer membrane porins in pathogenic Neisseria spp.
jcm.asm.org /cgi/content/full/40/10/3741   (4806 words)

  
 The Emergence of Neisseria gonorrhoeae with Decreased Susceptibility to Ciprofloxacin in Cleveland, Ohio: Epidemiology ...
The Emergence of Neisseria gonorrhoeae with Decreased Susceptibility to Ciprofloxacin in Cleveland, Ohio
Incidence rates of urethral isolates of Neisseria gonorrhoeae with decreased susceptibility to ciprofloxacin among men treated at one sexually transmitted disease clinic in Cleveland, Ohio, between January 1991 and September 1995.
Characterization of Neisseria gonorrhoeae Strains with Decreased Susceptibility to Fluoroquinolones Isolated in Greece from 1996 to 1999
www.annals.org /cgi/content/full/125/6/465   (3178 words)

  
 Morbidity and Mortality Weekly Report: Plasmid-mediated antimicrobial resistance in Neisseria gonorrhoeae - United ...
Because the prevalence of antimicrobial resistance in Neisseria gonorrhoeae increased during the early 1980s (1), in 1986 CDC implemented the Gonococcal Isolate Surveillance Project (GISP) to monitor antimicrobial susceptibilities at 21 collaborating sexually transmitted disease clinics in 21 cities (Figure 1) (2).
In 1985, based on previously described resistance caused by chromosomal mutations, CDC recommended that tetracycline not be used as sole therapy for gonorrhea (6); the subsequent emergence of TRNG has further emphasized the importance of this recommendation.
Neisseria gonorrhoeae is due to the acquisition of the streptococcal tetM determinant.
www.findarticles.com /p/articles/mi_m0906/is_n17_v39/ai_9035769   (1197 words)

  
 Neisseria gonorrhoeae, DNA Probe
Neisseria gonorrhoeae by DNA Probe (With Confirmation) is available at an additional charge; order test 164210.
gonorrhoeae is the culture of the microorganism; however, this organism is especially fastidious.
McCormack WM, "Clinical Spectrum of Infection With Neisseria gonorrhoeae," Sex Transm Dis, 1981, 8(4 Suppl):305-7.
www.labcorp.com /datasets/labcorp/html/chapter/mono/se036600.htm   (551 words)

  
 NGC - NGC Summary
gonorrhoeae infections are subdivided into those that are designed for 1) batch testing in a laboratory or 2) point-of-care testing as single tests or a limited number of tests performed while patients await results.
gonorrhoeae in urogenital, pharyngeal, or rectal swab specimens.
gonorrhoeae are not sufficiently sensitive and specific for them to be used among either victims or alleged assailants implicated in sexual assaults.
www.guideline.gov /summary/summary.aspx?doc_id=3483   (3239 words)

  
 Multi-level Antimicrobial Susceptibility Testing Resources (MASTER)
Urethral specimens were collected for detection of Neisseria gonorrhoeae and Chlamydia trachomatis using nucleic acid amplification tests (NAATs) and the patient was empirically given a single 500-mg dose of ciprofloxacin orally and a single 1-g dose of azithromycin.
gonorrhoeae are useful for the majority of specimens received in the clinical laboratory.
Multidrug-resistant Neisseria gonorrhoeae with decreased susceptibility to cefixime-Hawaii, 2001.
www.phppo.cdc.gov /DLS/master/select_documents.aspx?type=1&cat=17   (1460 words)

  
 AEGiS-MMWR: Current Trends Disk Diffusion Antimicrobial Susceptibility Testing of Neisseria gonorrhoeae
Antimicrobial resistance in Neisseria gonorrhoeae has developed to each of the agents that have been recommended for gonorrhea therapy (1).
Strains of N. gonorrhoeae that have chromosomally mediated resistance to antimicrobial agents or plasmid-mediated resistance to penicillin and/or tetracycline may be detected by measuring their susceptibilities by disk diffusion tests.
High-level tetracycline resistance in Neisseria gonorrhoeae is the result of the acquisition of the streptococcal tetM determinant.
www.aegis.com /pubs/MMWR/1990/MM3910-167.html   (1576 words)

  
 Susceptibilities of Neisseria gonorrhoeae to fluoroquinolones and other antimicrobial agents in Hyogo and Osaka, Japan ...
Evolution in the trends of antimicrobial resistance in Neisseria gonorrhoeae isolated in Durban over a 5 year period: impact of the introduction of syndromic management.
Plasmid analysis of Neisseria gonorrhoeae isolates and dissemination of tetM genes in southern Africa 1993–1995.
A remarkable reduction in the susceptibility of Neisseria gonorrhoeae isolates to cephems and the selection of antibiotic regimen for the single-dose treatment of gonococcal infection in Japan.
sti.bmjjournals.com /cgi/content/full/80/2/105   (1287 words)

  
 Fluoroquinolone-Resistant Neisseria gonorrhoeae -- San Diego, California, 1997
Decreased susceptibility of Neisseria gonorrhoeae to fluoroquinolones -- Ohio and Hawaii, 1992-1993.
Antimicrobial resistance in Neisseria gonorrhoeae in the United States, 1988-1994: the emergence of decreased susceptibility to the fluoroquinolones.
Proposed criteria for interpretation of susceptibilities of strains of Neisseria gonorrhoeae to ciprofloxacin, ofloxacin, enoxacin, lomefloxacin, and norfloxacin.
wonder.cdc.gov /wonder/prevguid/m0053026/m0053026.asp   (1719 words)

  
 Expression of AniA, the Major Anaerobically Induced Outer Membrane Protein of Neisseria gonorrhoeae, Provides ...
gonorrhoeae RUG7035 (ani[Con]) (squares) and F62 (circles) were grown aerobically in broth until mid-log phase, after which they were assayed for resistance to killing by normal human serum as described in the text.
Neisseria gonorrhoeae from the bactericidal action of normal human serum.
Binding of complement factor H to loop 5 of porin protein 1A: a molecular mechanism of serum resistance of nonsialylated Neisseria gonorrhoeae.
iai.asm.org /cgi/content/full/68/7/4368   (1389 words)

  
 Binding and accumulation of hemin in Neisseria gonorrhoeae -- Desai et al. 63 (12): 4634 -- Infection and Immunity
Binding and accumulation of hemin in Neisseria gonorrhoeae -- Desai et al.
Binding and accumulation of hemin in Neisseria gonorrhoeae
Although [14C]hemin was found to support the growth of N. gonorrhoeae, we did not detect the uptake of 14C from radiolabeled hemin.
iai.asm.org /cgi/content/abstract/63/12/4634   (547 words)

  
 Morbidity and Mortality Weekly Report: Decreased susceptibility of Neisseria gonorrhoeae to fluoroquinolones - Ohio and ...
Decreased susceptibility of Neisseria gonorrhoeae to fluoroquinolones - Ohio and Hawaii, 1992-1994
Agar dilution and disk-diffusion susceptibilities to ciprofloxacin and ofloxacin of strains of Neisseria gonorrhoeae with decreased susceptibilities to ciprofloxacin-- Ohio and Hawaii
CDC will continue to monitor the susceptibilities of N. gonorrhoeae strains to fluoroquinolones and other antimicrobial agents through GISP and other surveillance systems and is reassessing the appropriateness of fluoroquinolones in gonorrhea therapy in the United States.
www.findarticles.com /p/articles/mi_m0906/is_n18_v43/ai_15282473   (1223 words)

  
 Morbidity and Mortality Weekly Report: Fluoroqulnolone-Resistnt Neisseria gonorrhoeae - San Diego, California, 1997
The culture grew N. gonorrhoeae and was sent to the GISP laboratory for susceptibility testing.
Among the 26 clinics participating in GISP, the overall prevalence of N. gonorrhoeae with decreased susceptibility to ciprofloxacin was 0.3% in 1991 (5) and 0.4% in January-June 1997 (CDC, unpublished data).
The spread of fluoroquinolone-resistant N. gonorrhoeae locally may be limited by the frequent use of cephalosporins for treating gonorrhea.
www.findarticles.com /p/articles/mi_m0906/is_n20_v47/ai_20781819   (1296 words)

  
 What is Neisseria gonorrhoeae?
The prevalence of gonorrhea (Neisseria gonorrheae) in the United States and abroad, especially under-developed and developing countries, has decreased in the last two decades.
In 1963, the first quinolone antibiotic, nalidixic acid, was approved by the Food and Drug Administration for the treatment of urinary tract infections; however, it had several limitations, such as it had a narrow spectrum of activity, and bacteria quickly developed resistance to it (CTR, 1997).
gonorrhoeae strains, the CDC has instituted the Gonococcal Isolate Surveillance Project (GISP), which is a cooperative group of twenty-six sexually transmitted disease clinics across the United States that collect gonorrhea specimens and send them to regional offices for resistance diagnosis (CDC Update, 2000).
biology.kenyon.edu /slonc/bio38/stancikd_02/What_is_Neisseria_gonorrhoeae.html   (609 words)

  
 American Family Physician: Increases in fluoroquinolone-resistant neisseria gonorrhoeae
Fluoroquinolones are used frequently to treat gonorrhea in the United States because they are inexpensive and easy to administer and their continued use might decrease the use of cephalosporins and delay the development of cephalosporin resistance.
However, local and national data suggest that the prevalence of fluoroquinolone-resistant N. gonorrhoeae (QRNG) among men who have sex with men infected with gonorrhea is close to or exceeds 5 percent.
While this level of resistance often is used as the level at which a therapeutic regimen should be changed, other factors, including prevalence of gonorrhea, availability of antimicrobial susceptibility data, and cost of various diagnostic and treatment options, might result in higher or lower thresholds for change.
www.findarticles.com /p/articles/mi_m3225/is_3_70/ai_n6159439   (878 words)

  
 Emergence and Spread of Neisseria gonorrhoeae Clinical Isolates Harboring Mosaic-Like Structure of Penicillin-Binding ...
Quinolone-resistant Neisseria gonorrhoeae: correlation of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV with antimicrobial susceptibility profiles.
Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones, central Japan, 2001-2002.
Recruitment of a penicillin-binding protein gene from Neisseria flavescens during the emergence of penicillin resistance in Neisseria meningitidis.
aac.asm.org /cgi/content/full/49/1/137   (3204 words)

  
 The membrane phospholipids of Neisseria meningitidis and Neisseria gonorrhoeae as characterized by fast atom ...
The phospholipids of Neisseria meningitidis and Neisseria gonorrhoeae
The absence of a FabA homologue in Neisseria
Karow, M., Fayet, O. and Georgopoulos, C. The lethal phenotype caused by null mutations in the Escherichia coli htrB gene is suppressed by mutations in the accBC operon, encoding two subunits of acetyl coenzyme A carboxylase.
mic.sgmjournals.org /cgi/content/full/146/8/1901   (4579 words)

  
 Neisseria gonorrhoeae   (Site not responding. Last check: 2007-10-21)
The Neisseria gonorrhoeae strain FA1090 genome was sequenced by the University of Oklahoma and is available at GenBank (accession: AE004969).
The project was a joint effort between Dr.Dave Dyer of the Department of Microbiology and Immunology at the University of Oklahoma Health Sciences Center and Dr. Bruce Roe of the Advanced Center for Genome Technology, in the Department of Chemistry at Oklahoma University.
The analysis of the Neisseria gonorrhoeae genome is work in progress (e.g.
hpv-web.lanl.gov /stdgen/bacteria/ngon   (350 words)

  
 Neisseria gonorrhoeae, DNA Probe With Confirmation
It is very important to control the spread of this disease between sexual partners; consequently, the use of a quick, reliable test is essential.
Lind I, "Epidemiology of Antibiotic Resistant Neisseria gonorrhoeae in Industrialized and Developing Countries," Scand J Infect Dis, 1990, 69:77-82 (review).
Panke ES, Yang LI, Leist PA, et al, "Comparison of Gen-Probe® DNA Probe Test and Culture for the Detection of Neisseria gonorrhoeae in Endocervical Specimen," J Clin Microbiol, 1991, 29:883-8.
www.labcorp.com /datasets/labcorp/html/chapter/mono/mb024500.htm   (565 words)

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