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| | eMedicine - Nephrotic Syndrome : Article by Mahendra Agraharkar, MD, FACP |
 | | The histological classifications of glomerular lesions associated with primary and secondary nephrotic syndrome are minimal-lesion nephrotic syndrome, diffuse mesangial hypercellularity, focal glomerulosclerosis, membranous glomerulonephritis, fibrillary glomerulosclerosis, and membranoproliferative glomerulonephritis. |
 | | In persons with nephrotic syndrome, the concentration of heparan sulfate mucopolysaccharide in the basement membrane is lower, and large amounts of protein cross the barrier and are excreted. |
 | | Adult nephrotic syndrome: Note that a renal biopsy is not indicated in adults when the nephrotic syndrome is due to an obvious cause such as diabetes mellitus, ie, when the patient has other diabetes-related overt complications. |
| www.emedicine.com /MED/topic1612.htm (6309 words) |
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