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	Neupogen (Site not responding. Last check: 2007-10-22)
		Neupogen is similar to a naturally occurring protein which stimulates the colonies of white stem cells within the bone marrow causing the level of neutrophils in the blood to rise (Granulocyte Colony Stimulating Factor - GCSF).
		Neupogen is given as an injection under the skin (subcutaneous) containing 30 or 48 million units of filgrastim in a pre-filled syringe.
		Neupogen is generally well tolerated and it is often difficult to separate the mild side effects from those caused by the chemotherapy.
	www.cancernet.co.uk /neupogen.htm (944 words)

	CDC Radiation Emergencies \| Facts About Neupogen®
		Filgrastim (trade name Neupogen®), is a drug that was approved for use by the FDA in 1991 for cancer patients with bone marrow damage due to chemotherapy or radiotherapy.
		Neupogen may also be useful for patients who have bone marrow damage from accidental exposures to high doses of radiation and it is expected to provide similar benefits.
		Neupogen® is a specific type of cytokine that stimulates the growth of white blood cells.
	www.bt.cdc.gov /radiation/neupogenfacts.asp (676 words)

	Data Sheet
		Treatment with Neupogen in patients undergoing cytotoxic chemotherapy or myeloablative therapy followed by bone marrow transplantation leads to a significant reduction in the incidence, severity and duration of neutropenia and febrile neutropenia, and consequently, fewer admissions to the hospital, shorter duration of hospitalisation and less antibiotics as compared to patients on cytotoxic chemotherapy alone.
		Neupogen is indicated for the mobilisation of autologous peripheral blood progenitor cells alone, or following myelosuppressive chemotherapy and the mobilisation of peripheral blood progenitor cells in normal donors (allogeneic PBPC).
		Neupogen should not be administered to patients with known hypersensitivity to filgrastim or to any of the excipients.
	www.medsafe.govt.nz /profs/Datasheet/n/Neupogeninj.htm (5335 words)

	Neupogen news articles
		NEUPOGEN is indicated for reducing the time to neutrophil recovery and the duration of fever, following induction or consolidation hemotherapy treatment of adults with AML.
		NEUPOGEN is indicated to decrease the incidence of infection as manifested by febrile neutropenia in patients with nonmyeloid malignancies receiving myelosuppressive anticancer drugs associated with a significant incidence of severe neutropenia with fever.
		NEUPOGEN is indicated to reduce the duration of neutropenia and neutropenia-related clinical sequelae, eg, febrile neutropenia, in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by marrow transplantation.
	www.onconews.org /medications/Neupogen.html (952 words)

	Neupogen / Filgrastim : Article (Site not responding. Last check: 2007-10-22)
		Neupogen is manufactured by Amgen Pharmaceuticals and is used to stimulate white blood cell development in cancer patients undergoing chemotherapy.
		Neupogen is known as a "colony stimulating factor" as it prompts a cancer patient's bone marrow to create white blood cells.
		Additionally, during the summer of 2001, a Kansas City pharmacist was arrested for diluting Neupogen doses that were later given to cancer patients.
	www.injuryissues.com /find/topic-763.html (315 words)

	LCD : Neupogen (Filgrastim) and Neulasta (Pegfilgrastim) (L13239) (Site not responding. Last check: 2007-10-22)
		Therapy with Neupogen and Neulasta is recommended in conditions in which worsening of the course is predicted, there is an expected long delay in recovery of the marrow, patients remain severely neutropenic and have documented infections that do not respond to appropriate antimicrobial therapy.
		Neupogen is indicated to decrease the incidence of infection, manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia.
		Neupogen is indicated to reduce the duration of neutropenia and neutropenia-related clinical sequelae (e.g.
	www.riverbendgba.com /vlmrp/13239.html (2500 words)

	[No title]
		However, by late 96, Epogen and Neupogen were increasingly viewed as "maturing" drugs and the investment community was concerned that the strong growth rates of Epogen and Neupogen were going to slow dramatically and that this would adversely impact Amgen's EPS growth.
		Neupogen, which boosts white blood cell count and helps alleviate the side effects of chemotherapy, showed a five percent increase in worldwide sales in the first quarter, down from a 10 percent growth rate in the fourth quarter of 1996.
		Neupogen growth stronger for cancer, weaker for AIDS Sales of Neupogen increased 6.8% for the quarter, to $272.0 million from $254.7 million in the same quarter of 1996.
	securities.stanford.edu /1011/AMGN98/civ183029.txt (14827 words)

	Product Label
		NEUPOGEN therapy was adjusted to maintain the median ANC between 1500 and 10‚000/mm3.
		NEUPOGEN dosing requirements were generally higher for patients with congenital neutropenia (2.3 to 40 mcg/kg/day) than for patients with idiopathic (0.6 to 11.5 mcg/kg/day) or cyclic (0.5 to 6 mcg/kg/day) neutropenia.
		NEUPOGEN diluted to concentrations between 5 and 15 mcg/mL should be protected from adsorption to plastic materials by the addition of Albumin (Human) to a final concentration of 2 mg/mL.
	www.accessdata.fda.gov /scripts/cder/onctools/labels.cfm?GN=Filgrastim (4875 words)

	Neupogen (Site not responding. Last check: 2007-10-22)
		Neupogen is an injectable prescription treatment that stimulates the bone marrow to make more infection-fighting white blood cells called neutrophils—exactly as your own body does when you're healthy.
		Neupogen does not eliminate the risk of infection entirely, but it does minimize your risk, day by day.
		Once your doctor has prescribed Neupogen, continuing Neupogen throughout your chemotherapy will help guard against future infections, as patients experiencing low white blood cell counts after one cycle are more likely to experience low counts with future cycles.
	www.bymyside.com /neupogen.html (466 words)

	Neupogen
		Neupogen is a rather new addition to the armaments of medical oncologists.
		In cases of severe lowering of the blood cells, Neupogen could be given at higher doses and even intravenously.
		Neupogen stimulates the bone marrow cells to produce more white blood cells.
	www.tirgan.com /neupogen.htm (131 words)

	Neupogen Information from Drugs.com
		Neupogen is used to increase white blood cells, and to decrease the risk of infection, in conditions such as cancer; bone marrow transplant; pre-chemotherapy blood cell collection; and severe chronic neutropenia including congenital neutropenia, cyclic neutropenia, and idiopathic neutropenia.
		Neupogen is in the FDA pregnancy category C. This means that it is not known whether Neupogen will be harmful to an unborn baby.
		Symptoms of a Neupogen overdose are not known.
	www.drugs.com /neupogen.html (1492 words)

	Neupogen and Neupogen Side Effects - Chemotherapy Drugs
		Neupogen is used to stimulate the production of granulocytes (a type of white blood cell) in patients undergoing therapy that will cause low white blood cell counts.
		Neupogen is used to prevent infection and neutropenic (low white blood cells) fevers caused by chemotherapy.
		Neupogen may be given by subcutaneous (the layer between the skin and muscle) injection or infused into a vein (intravenous, IV).
	www.chemocare.com /BIO/neupogen.asp (1156 words)

	Neupogen
		I had 4 sequential shots of neupogen my 3rd round of AC and did not have this amount of pain.
		Dear valpal, Usually aches and pains associated with neupogen happen within a day or two of injection and subside after a day or two.
		Neupogen was prescribed as a preventive only because I changed regimens and the new chemo regimen is very aggressive.
	www.medhelp.org /forums/BreastCancer/messages/2132.html (471 words)

	Consumer Medicine Information
		Although NEUPOGEN is not a treatment for cancer, it does help the body to make new neutrophils, and this will reduce your chance of developing infections that might require treatment with antibiotics and/or hospital stays.
		NEUPOGEN helps the body to make and maintain the right number of infection-fighting neutrophils, decreasing the risk of infection and the need for antibiotics and/or hospital stays.
		NEUPOGEN is sometimes given by injection into a vein - this is called an intravenous injection and is normally given by a doctor or nurse.
	www.medsafe.govt.nz /Consumers/cmi/n/Neupogen.htm (3180 words)

	Neupogen (Site not responding. Last check: 2007-10-22)
		Neupogen is copied from a naturally occurring human protein that acts to stimulate the production and release of particular white blood cells known as neutrophils.
		Neupogen (300mcg in 1ml vials or 0.5ml PFS) is a funded medicine under section H of the Pharmaceutical Schedule.
		Neupogen is a Prescription Medicine used in the treatment of cancer, bone marrow or stem cell transplants or donation, and treatment in advanced HIV infection.
	cancernz.co.nz /product.asp?id={E975057B-B30B-46EB-977B-B0D37D036E3E} (345 words)

	NEUPOGEN® Filgrastim - Product Information
		The detection of antibody formation is highly dependent on the sensitivity and specificity of the assay, and the observed incidence of antibody positivity in an assay may be influenced by several factors including timing of sampling, sample handling, concomitant medications, and underlying disease.
		Generally adverse events observed in nonrandomized studies were similar to those seen in randomized studies occurred in a minority of patients, and were of mild-to-moderate severity.
		Doses may be increased in increments of 5 mcg/kg for each chemotherapy cycle according to the duration and severity of the ANC nadir.
	www.neupogen.com /pi.html (7860 words)

	afebrile neutropenia and neupogen
		My limited research finds, however, that prophylactic neupogen administration is not recommended in practice guidelines because outcomes are not improved (even though neutrophil recovery is improved).
		Dear mora224: The primary reason for using growth factors such as neupogen or neulasta is to be able to maintain the full dose and schedule of the chemotherapy regimen.
		In these cases, if your white count were ever to drop low enough that the chemo would be dose reduced or delayed, the use of neupogen would likely be commenced with the next dose and continued throughout treatment.
	www.medhelp.org /forums/BreastCancer/messages/1918.html (595 words)

	Neupogen - Talk Medical
		· Neupogen is used to increase white blood cells, and to decrease the risk of infection, in conditions such as cancer; bone marrow transplant; pre-chemotherapy blood cell collection; and severe chronic neutropenia including congenital neutropenia, cyclic neutropenia, and idiopathic neutropenia.
		Neupogen can remain at room temperature for up to 24 hours.
		Continue to use Neupogen and talk to your doctor if you experience: ·bone pain; ·nausea; or ·swelling, redness, or pain at the injection site.
	www.talkmedical.com /medications/4250/Neupogen (917 words)

	Neupogen (Site not responding. Last check: 2007-10-22)
		Neupogen is used to boost the white blood cells after chemotherapy
		Neupogen is used to stimulate the growth of white blood cells after you have received your chemotherapy.
		The company that makes Neupogen has now developed a new drug called Neulasta, which means that instead of having to give yourself an injection every day, you now only need to get the one injection, that will work over a period of time.
	homepage.ntlworld.com /lawrence.wray1/neupogen (297 words)

	neupogen drug information, neupogen side effects
		NEUPOGEN® is a 175 amino acid protein manufactured by recombinant DNA technology.1 NEUPOGEN® is produced by Escherichia coli...
		Filgrastim (trade name Neupogen®), is a drug that was approved for use by the FDA in 1991 for...
		Offers comprehensive cancer treatment guide, drugs such as Neupogen or Neulasta, chemotherapy side effects, chemo treatment, infection risk management, cancer treatment support and resources that may help your cancer treatment to be successful.
	www.drugs.com /drug/neupogen (563 words)

	Long-Term Study Shows Safety of Neupogen® in AML Treatment
		Acute myeloid leukemia (AML) is a cancer of the bone marrow and blood characterized by the rapid, uncontrolled growth of immature white blood cells known as myelocytes.
		Agents such as Neupogen or Neulasta® (pegfilgastrim) are available to stimulate the body to produce more immune cells.
		The researchers concluded that the use of Neupogen does not increase the long-term risk of death when used to treat patients with AML.
	patient.cancerconsultants.com /news.aspx?id=36516 (460 words)

	Neupogen
		Neupogen costs about $200 per shot and is often covered by your health insurance ONLY when your white blood cell count is low enough to make it fit within the "rationing program" of the insurance company.
		You must be alert and look for some of the common signs of infection, such as fever, chills, rash, sore throat, diarrhea, or redness, swelling, or pain around a cut or sore.
		Permission is granted to download, copy, distribute and use as long as the copyright notice remains attached to such use and the intended meaning is not altered.
	www.oxygentimerelease.com /B/Bonnie/p17.htm (787 words)

	Long-Term Study Shows Safety of Neupogen® Support in AML Treatment
		Short-term observations have demonstrated that the administration of Neupogen to support induction and consolidation chemotherapy in patients with AML hastens recovery of neutrophils and does not have an adverse impact on relapses.
		Neupogen hastened neutrophil recovery by 5 days compared to placebo.
		There were no differences in the number of deaths in the Neupogen group compared to placebo.
	professional.cancerconsultants.com /oncology_main_news.aspx?id=36511 (518 words)

	095-03 Neupogen and Neulasta (Site not responding. Last check: 2007-10-22)
		Neupogen and Neulasta are not routinely used in every instance of febrile neutropenia.
		At your request this document is appended to the policy and is referenced in the indications.
		Neupogen or Neulasta with the very first course of chemotherapy.
	www.riverbendgba.com /vlmrp/095-03FAQ.html (2190 words)

	neupogen booster (Site not responding. Last check: 2007-10-22)
		Otherwise both Neupogen and Neulasta work in the same way) in a pre-emptive fashion reduced febrile neutropenia by 94%, hospitalizations by 93% and need for intravenous antibiotics for opportunistic infections by 80%.
		In this case the monoclonal antibody that is being helped by Neupogen goosed neutrophils is Nd2, effective in pancreatic cancer.
		Most times, the Neupogen shots are needed any way, it is just that giving them up-front makes so much more sense, rather than on an ad-hoc basis after the problems of neutropenia have set in.
	www.clltopics.org /RituxanEnhancements/neupogen_as_booster.htm (5199 words)

	Neupogen
		Neupogen injection contains the active ingredient filgrastim, which is a type of medicine called a recombinant human granulocyte-colony stimulating factor (G-CSF).
		G-CSF is a substance produced naturally by the body that stimulates the bone marrow to produce white blood cells known as neutrophils.
		Neupogen should be stored in the refrigerator at 2 to 8°C. You will need to have regular blood tests to monitor the numbers of blood cells in your blood while you are receiving treatment with this medicine.
	www.netdoctor.co.uk /medicines/100001828.html (1015 words)

	Remission.org - Diary (Treatment)
		Neupogen Shots - Doctor is surprised at how well my WBC has held up.
		May be able to go back to three Neupogen shots a treatment.
		In fact, WBC was so high that the doctor volunteered that three Neupogen injections would probably be enough this time.
	www.remission.org /diary/diary1.shtml (4989 words)

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