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Topic: Neuroblastoma


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In the News (Thu 31 Dec 09)

  
  MedlinePlus Medical Encyclopedia: Neuroblastoma
Neuroblastoma is a malignant (cancerous) tumor that develops from nerve tissue.
Neuroblastoma most commonly begins in the abdomen in the tissues of the adrenal gland, but it may also occur in other areas.
In very young children with neuroblastoma, the tumor may go away on its own, without any treatment, or the tissues of the tumor may mature and develop into a benign ganglioneuroma that can be surgically removed.
www.nlm.nih.gov /medlineplus/ency/article/001408.htm   (571 words)

  
  Neuroblastoma Treatment - National Cancer Institute
Neuroblastoma is a disease in which malignant (cancer) cells form in nerve tissue of the adrenal gland, neck, chest, or spinal cord.
Neuroblastoma often begins in the nerve tissue of the adrenal glands.
Neuroblastoma may also begin in the chest, in nerve tissue near the spine in the neck, or in the spinal cord.
www.cancer.gov /cancerinfo/pdq/treatment/neuroblastoma/patient   (967 words)

  
 Children's Neuroblastoma Cancer Foundation - Home
Through our experience with neuroblastoma and network of families and medical professionals, we are committed to use our experience as a tool in supporting the needs of the children and their families and provide funding to the medical community for new and advanced research studies.
Neuroblastoma is a solid tumor cancer that begins in the nerve tissue in the neck, chest, abdomen, or pelvis but usually originates in the abdomen in the tissue of the adrenal gland.
Prognosis for neuroblastoma is dependent on age, stage of disease, and the molecular biologic and cytogenetic characteristics of the tumor.
www.cncf-childcancer.org   (703 words)

  
 Neuroblastoma Information on Healthline
Neuroblastoma is a type of cancer that usually originates either in the tissues of the adrenal gland or in the ganglia of the abdomen or in the ganglia of the nervous system.
The first symptom of a neuroblastoma is usually an unusual growth or lump, found in most cases in the abdomen of the child, causing discomfort or a sensation of fullness and pain.
In general, the prognosis for a young child with neuroblastoma is good: the predicted five-year survival rate is approximately 85% for children who had the onset of the disease in infancy, and 35% for those whose disease developed later.
www.healthline.com /galecontent/neuroblastoma   (1150 words)

  
 Neuroblastoma definition - Medical Dictionary definitions of popular medical terms easily defined on MedTerms
Neuroblastoma: A leading childhood form of cancer that arises in the adrenal gland or in tissue in the nervous system that is related to the adrenal gland.
Neuroblastoma is predominantly a tumor of early childhood; two thirds of children with neuroblastoma are diagnosed when they are younger than 5 years of age.
The prognosis for patients with neuroblastoma is related to their age at diagnosis (the younger, the better the prognosis), clinical stage of their disease, and (in patients older than 1 year of age) whether they do or do not have regional lymph node involvement by the tumor.
www.medterms.com /script/main/art.asp?articlekey=4550   (762 words)

  
 Neuroblastoma
Neuroblastoma is a cancerous tumor that begins in nerve tissue of infants and very young children.
Neuroblastoma is rare in children older than 10 years of age, however, it does occur occasionally in adults.
Most neuroblastoma cells have genetic abnormalities involving chromosome #1, where a deletion or rearrangement is found on the short arm of this chromosome.
www.healthsystem.virginia.edu /uvahealth/peds_oncology/nbt.cfm   (1457 words)

  
 eMedicine - Neuroblastoma : Article by Norman J Lacayo
MYCN is an overexpressed oncogene in neuroblastoma with the amplification of the distal arm of chromosome 2.
Most patients with neuroblastoma present with disseminated disease, which confers a poor prognosis and is associated with a high mortality rate.
Primary cervical neuroblastoma is rare but should be considered in the differential diagnosis of masses of the neck, especially in infants younger than 1 year with feeding or respiratory difficulties.
www.emedicine.com /ped/topic1570.htm   (9006 words)

  
 APSA :: Resources for Parents : Neuroblastoma   (Site not responding. Last check: )
Neuroblastoma is a tumor that may arise at any site in the sympathetic nervous system, including the brain, neck (3%), chest next to the spine (20%), abdomen on either side of the aorta (24%), pelvis (3%), and adrenal gland (50%) (Figure 1).
Neuroblastoma cells secrete many products, including hormones (e.g., vasoactive substances (substances that affect the blood vessels), including catecholamines (the “fight or flight” hormones that raise our heart rate and blood pressure when we are scared) and their byproducts (homovanillic acid [HVA], vanillylmandelic acid [VMA], 3-methoxytyramine, metanephrines, and dopamine).
During removal of neuroblastomas in the chest, it is often impossible to avoid leaving small amounts of tumor along the nerves as they emerge from the spine.
www.eapsa.org /parents/neuroblastoma.cfm   (4132 words)

  
 Cancer Information, Research, and Treatment for all Types of Cancer | OncoLink
Neuroblastoma is a tumor of nerve tissue that most commonly comes from the abdomen (the adrenal glands, which sit on top of the kidneys), but can also start in the neck, chest, or pelvis.
Neuroblastoma is mainly a tumor of infancy and early childhood.
Neuroblastoma cells with increased amounts of DNA are termed hyperdiploid, and in infants, hyperdiploid cells are associated with earlier stages of disease, better response to therapy, and thus a generally better outcome than diploid cells.
www.oncolink.com /types/section.cfm?c=14&s=51   (1749 words)

  
 Neuroblastoma   (Site not responding. Last check: )
Neuroblastoma is a relatively rare childhood cancer that occurs in one out of every 100,000 children.
Neuroblastoma is a cancer of the nerve cells.
Neuroblastoma is most common in infants and children five-years-old and younger, and is more common in boys than girls.
www.hopkinskimmelcancercenter.org /scout/types/neuroblastoma.cfm   (572 words)

  
 Neuroblastoma - My Child Has - Children's Hospital Boston
Neuroblastoma is a cancerous tumor that begins in nerve tissue of infants and very young children.
Neuroblastoma is rare in children older than 10 years of age, however, it does occur occasionally in adults.
About one-third of neuroblastomas may begin in the adrenal glands, but many others begin in the ganglia, clusters of nerve cells found throughout the body that are part of the nervous system.
www.childrenshospital.org /az/Site1084/mainpageS1084P0.html   (3036 words)

  
 Neuroblastoma
Neuroblastoma is predominantly a tumor of early childhood, with two thirds of the cases presenting in children younger than 5 years of age.
The prognosis for patients with neuroblastoma is related to their age at diagnosis, clinical stage of disease, and (in patients older than 1 year of age) regional lymph node involvement.
Children of any age with localized neuroblastoma and infants younger than 1 year of age with advanced disease and favorable disease characteristics have a high likelihood of long-term, disease-free survival.[8,11] Older children with advanced-stage disease, however, have a significantly decreased chance for cure despite intensive therapy.
www.meds.com /pdq/neurob_pro.html   (5380 words)

  
 Neuroblastoma
Neuroblastoma is a childhood cancer that grows in parts of the nervous system.
Neuroblastoma can also spread to the skin, producing small bumps, or nodules, and to the spinal cord, which can cause weakness in the arms or legs and even paralysis.
Neuroblastoma that is diagnosed as recurrent continues to spread after treatment, or comes back at a later time.
www.hmc.psu.edu /childrens/healthinfo/n/neuroblastoma.htm   (861 words)

  
 Neuroblastoma - MayoClinic.com
Neuroblastoma is a cancer that develops from nerve cells found in several areas of the body.
Neuroblastoma most commonly affects children age 5 or younger, though it may rarely occur in older children and adults.
Neuroblastoma develops in tissue that makes up the sympathetic nervous system — the system of nerves that automatically regulates your heart rate, blood pressure and digestion.
www.mayoclinic.com /health/neuroblastoma/DS00780   (263 words)

  
 Neuroblastoma
Neuroblastoma is predominantly a tumor of early childhood, with two thirds of the cases presenting in children younger than 5 years.
The prognosis for patients with neuroblastoma is related to their age at diagnosis, clinical stage of disease, and, in patients older than 1 year, regional lymph node involvement.
European studies suggest that the inclusion of chromosome 1p status of neuroblastoma cells may improve risk grouping [8] and the clinical significance of additional tumor genetic characteristics including 17q gain, 1p deletion, and 11q deletion are under study.
imsdd.meb.uni-bonn.de /cancer.gov/CDR0000062786.html   (10336 words)

  
 Neuroblastoma in children : Cancerbackup   (Site not responding. Last check: )
The treatment of neuroblastoma depends on the age of the child, the size and position of the tumour, the tumour biology, and whether the neuroblastoma has spread.
If the neuroblastoma has spread to several parts of the body, or is high risk, high-dose chemotherapy with stem cell rescue is used (after the initial courses of chemotherapy).
If the neuroblastoma has spread to several parts of the body or is high risk, external radiotherapy may be given.
www.cancerbackup.org.uk /Cancertype/Childrenscancers/Typesofchildrenscancers/Neuroblastoma   (1769 words)

  
 ENLmedical.com: Conditions And Concerns: Medical Encyclopedia: Neuroblastoma
Neuroblastoma most commonly begins in the abdomen in the tissues of the adrenal gland but may occur in other areas.
Pepper's syndrome is a neuroblastoma that originates in the adrenal gland and usually metastasizes to the liver.
Some children with neuroblastoma experience spontaneous regression of the tumor, where the tissues of the tumor mature and develop into a benign ganglioneuroma that can be surgically removed.
www.enlmedical.com /article/001408.htm   (508 words)

  
 Causes of Neuroblastoma: New Warnings about Where You Live
Neuroblastoma is one of the most common cancers affecting children today, forming 8%-10% of the total seen from birth through age 14 years.
Neuroblastoma typically begins in the abdominal area either in the adrenal gland (located just above the kidney) or around the spinal cord in the neck, chest, or pelvis.
Because of the strong links of neuroblastoma and chlordane, it is very important that patient’s with neuroblastoma who are living in a home built before 1988 have their home tested for chlordane.
www.chem-tox.com /neuroblastoma/default.htm   (2705 words)

  
 Sloan-Kettering - Neuroblastoma
Mainly affecting children, neuroblastoma is a relatively rare cancer of the sympathetic nervous system -- a nerve network that carries messages from the brain throughout the body.
The cause of neuroblastoma is unknown, though most physicians believe that it is an accidental cell growth that occurs during normal development of the adrenal glands.
Neuroblastoma's first symptoms are often vague and may include fatigue and loss of appetite.
www.mskcc.org /mskcc/html/2868.cfm   (502 words)

  
 Neuroblastoma
The diagnosis of the neuroblastoma is defined as stage 3 with spinal epidural compression (the aspirations and the bone marrow biopsies carried out during the operation give negative results, as does the skeletral radiogram carried out a couple of days later).
This substance is connected to radioactive iodine and becomes caught specifically by the neuroblastoma cells, identifying the presence of either the tumour or its metastases.
It is also necessary to give a suitable explanation, according to their age, of neuroblastoma - if possible, one which is similar to that given to the ill child; the ill child, himself, if he is old enough, could even explain his illness, the therapy and the new routine to his brother or sister.
www.joeytubo.com /neuroblastoma.htm   (17429 words)

  
 Neuroblastoma - WrongDiagnosis.com
Neuroblastoma is a specific type of neuroblastic tumor which is characterized by the presense of neuroblastic cells forming groups or nests separated by delicate stromal septa without prominent Schwannian stroma.
Neuroblastoma is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
The prognosis of Neuroblastoma may include the duration of Neuroblastoma, chances of complications of Neuroblastoma, probable outcomes, prospects for recovery, recovery period for Neuroblastoma, survival rates, death rates, and other outcome possibilities in the overall prognosis of Neuroblastoma.
www.wrongdiagnosis.com /n/neuroblastoma/intro.htm   (684 words)

  
 Neuroblastoma
Neuroblastoma is one of the most common solid tumours of early childhood usually found in babies or young children.
Neuroblastoma Children's Cancer Society (USA) The NCCS is a non-profit organization dedicated to fund-raising, support, research, and advocacy for children with neuroblastoma and families.
Neuroblastoma Hope Foundation (ACOR) Information about diagnosis, treatment, genetics, survivorship and a broad range of issues, FAQ, bibliography, glossary etc. The site is by Honna Janes-Hodder who is an active patient advocate having lost her son to neuroblastoma.
www.cancerindex.org /ccw/guide2n.htm   (1837 words)

  
 Neuroblastoma Children's Cancer Society advocates for children who suffer from Neuroblastoma
Neuroblastoma is a children’s cancer diagnosed in approximately 500 to 1,000 children per year in the USA.
Neuroblastoma is a complex tumor of the sympathetic nervous system, a condition that has been known for 35 years.
The two most important factors in the prognosis for a child with neuroblastoma are the stage of the disease and the age of the child at the time of diagnosis.
www.neuroblastomacancer.org /scripts/content.cgi?template=default&args=main,education   (459 words)

  
 Neuroblastoma
Neuroblastoma is often present at birth, but is most often diagnosed much later when the child begins to show symptoms of the disease.
In about 90% of cases of neuroblastoma, elevated levels of catecholamines or its metabolites are found in the urine or blood.
If a child is diagnosed with neuroblastoma, more tests are performed to determine if the cancer has spread from where it started to other parts of the body, or "staged".
www.acor.org /ped-onc/diseases/neuro.html   (1917 words)

  
 The Neuroblastoma Society - Fighting Childhood Cancer
Neuroblastoma is a rare and aggressive childhood cancer.
About 100 children in the UK are diagnosed each year.
The Society works exclusively for these children in raising funds for British research into the disease and offering information and support for anyone affected by neuroblastoma.
www.nsoc.co.uk   (65 words)

  
 uhrad.com - Neuroradiology Imaging Teaching Files
Neuroblastoma is the 3rd most common malignancy of childhood behind leukemia and primary brain tumor.
Neuroblastoma often arise from the adrenal medulla but can also form anywhere along the sympathetic ganglion.
Pathologically, the neuroblastoma is in the spectrum with ganglioneuroma, a benign tumor, and ganglioneuroblastoma which is of intermediate malignant potential.
rd.business.com /index.asp?epm=s.1&bdcq=Neuroblastoma&bdcr=1&bdcu=http://www.uhrad.com/mriarc/mri031.htm&bdcp=&partner=2662601&bdcs=nwuuid-2662601-FC571EF1-319D-05B9-0132-57CD9A75BB1F-ym   (185 words)

  
 ACS :: What Is Neuroblastoma?
Neuroblastoma is a form of cancer that occurs in infants and young children.
About one third of neuroblastomas start in the adrenal glands and another third begin in the sympathetic nervous system ganglia of the abdomen.
Rarely, a neuroblastoma may have spread so extensively by the time it is found that doctors are unable to determine exactly where it started.
www.cancer.org /docroot/cri/content/cri_2_4_1x_what_is_neuroblastoma_31.asp   (541 words)

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