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Topic: Neurochemical

	neurochemical studies of pyritinol
		Neurochemical studies on the mechanism of action of
		In investigations carried out in young and old rats with pyritinol (pyrithioxin), a substance that is frequently applied in cognitive function disturbances, besides effects on general cerebral functions, possible interactions with cholinergic transmission were determined.
		Our results are in accordance with the recently described (Martin, 1987) elevation of cortical acetylcholine levels and facilitation of acetylcholine release under pyritinol and extend the functional relevance of these findings to the postsynaptic, cholinergically innervated cortical neurons.
	www.pyritinol.org /Pyritinol/Pyritinol-neurochemical-14.htm (241 words)

	[No title] (Site not responding. Last check: 2007-10-03)
		Neurochemical findings will be presented that reveal the chemical changes that take place due to regular caffeine use.
		The neurochemical effect of caffeine results in a suppression of adenosine receptor activity.
		The fatigue observed in caffeine deprived subjects could be due to the decrease in catecholamine release that is facilitated by the caffeine mediated upregulation of adenosine receptors.
	sulcus.berkeley.edu /mcb/165_001/papers/manuscripts/_861.html (3254 words)

	MAPS - Volume 5 Number 3 Winter 1994-95 - neurochemical markers and mdma neurotoxicity
		The neurochemical changes induced by MDMA would presumably result from a decrease in TPH (tryptophan hydroxylase) activity[17] occuring in otherwise intact 5-HT neurons.
		To what extent the neurochemical changes induced by MDMA are responsible for therapeutic or pathological changes in psychology also needs to be determined.
		Neurochemical and Neurohistological Alterations in the Rat and Monkey Produced by Orally Administered 3,4-Methylene-dioxymethamphetamine (MDMA).
	www.maps.org /news-letters/v05n3/05310neu.html (2576 words)

	Neurochemical Markers of Degenerative Nervous Diseases and Drug Addiction
		Establishing a primary role for neurochemical markers in any neurodegenerative disorder or in drug addiction is an important strategy in the design of new therapeutic agents for effective management of these clinical conditions in the future.
		The question is, however, whether these neurochemical markers reflect a primary neurophysiological or neurochemical event in the disease process or whether it reflects secondary events which appeared at the time of disease diagnosis.
		The aim of this book is to present as much detailed information as possible that is currently available on various neurochemical markers and their metabolic pathways, which may form the basis for future diagnostic support in various neurodegenerative disorders as well as in the tackling of the huge problem of drug addiction.
	www.vsppub.com /books/lifes/bk-NeuMarDegNerDisDruAdd.html (244 words)

	ipedia.com: Synaptic plasticity Article (Site not responding. Last check: 2007-10-03)
		Synaptic plasticity is part of the Hebbian theory about the neurochemical foundations...
		Synaptic plasticity is part of the Hebbian theory about the neurochemical foundations of memory and learning.
		Two known molecular mechanisms for synaptic plasticity were revealed by research in laboratories such as that of Eric Kandel.
	www.ipedia.com /synaptic_plasticity.html (203 words)

	Environmental Health Perspectives: Differential effects of two lots of Aroclor 125... @ HighBeam Research (Site not responding. Last check: 2007-10-03)
		In general, the data from neurochemical end points indicate that the effects of two lots of Aroclor 1254 on intracellular [Ca.sup.2+] buffering is comparable, but lot 124-191 was more effective on PKC translocation than was lot 6024.
		The differential effects of two lots of Aroclor 1254 on the selected neurochemical end points could not be clearly explained by the differences in their TEQ values.
		These effects also could not be attributed to the interactions among the congeners and contaminants because our previous studies indicated that inactive congeners did not interfere with the activity of active congeners, and the interactions between two active congeners seem to follow additivity (52).
	www.highbeam.com /library/doc0.asp?DOCID=1G1:82288609&refid=holomed_1 (4599 words)

	Neurochemical
		For this purpose, we will determine the neurochemical, neurobehavioral, and endocrine effects of in utero and lactational exposure of the laboratory rat to individual PCB congeners.
		These congeners were selected because they alter neurochemical and second messenger systems and the development of key endocrine systems including thyroid and estrogens- all of which are important for normal brain development.
		Animals will also be exposed to pharmacological agents during development to determine whether neurochemical and endocrine changes, seen after congener exposure, are due to selective alterations in these specific systems.
	www.albany.edu /sph/superfund/seegal.html (489 words)

	[No title]
		In this context the study of drug effects and the study of the neurochemical basis of brain function converge.
		However drugs have many effects, not all of which are explained by their actions on the brain, or on particular neurochemical systems - these we call side effects, but it must be remembered that they are just as genuine effects as the one we are primarily interested in.
		The problem of pharmacological specificity is to determine whether a given drug effect is mediated by the particular neurochemical system under study, and whether it depends on the appropriate pharmacological mechanism.
	www.psych.mcgill.ca /courses/522/UNIT2.htm (2824 words)

	BCS 243: Neurochemical Foundations of Behavior (Site not responding. Last check: 2007-10-03)
		The discipline of behavioral neurochemistry includes topics that range from study of the neurochemical mechanisms that underlie normal behavior to behavioral sequellae that result from severe neurochemical abnormalities.
		These issues will be considered in the final quarter of the course in a unit designated as functional neurochemistry.
		However, throughout the course, the function aspects of all neurochemical mechanisms will be discussed.
	www.bcs.rochester.edu /courses/243.index.html (170 words)

	Article: Breastfeeding: Brain Nutrients In Brain Development For Human Love And Peace
		These sensory deprivation processes that involve the emotional senses of body touch, movement and smell have been well described in failed affectional bonding in the mother-infant/child relationship that results in behavioral abnormalities of depression, impulse dyscontrol, violence and substance abuse; and in impaired immunological functioning in mother deprived infants.
		One of the brain neurochemical transmitter substances–serotonin–has been shown to be significantly reduced under conditions of failed mother-infant affectional bonding.
		This error of interpretation is compounded by the failure to realize that there is another neurobiological mechanism involved in the development of brain serotonin–tryptophan–a precursor amino acid essential for the development of brain serotonin which is richly present in colostrum and breastmilk but absent in formula milk.
	www.violence.de /prescott/ttf/article.html (2058 words)

	Specific Genetic Deficiencies of the A and B Isoenzymes of Monoamine Oxidase Are Characterized by Distinct ...
		Specific Genetic Deficiencies of the A and B Isoenzymes of Monoamine Oxidase Are Characterized by Distinct Neurochemical and Clinical Phenotypes -- Lenders et al.
		Specific Genetic Deficiencies of the A and B Isoenzymes of Monoamine Oxidase Are Characterized by Distinct Neurochemical and Clinical Phenotypes
		Neurochemical phenotyping may provide a sensitive tool for detection of the MAO-A deficiency state.
	www.jci.org /cgi/content/full/97/4/1010 (5174 words)

	ScienceDaily: Drug Abuse Behavior Driven By Neurochemical Changes In Brain
		The neurochemical changes in the brain that occur directly after cocaine use include a sharp increase in dopamine levels.
		This increase is believed responsible for cocaine's euphoric effects because dopamine is the most important neurochemical in the brain's "reward system," which is involved in normal pleasurable activities like eating and sex.
		Scientists have known for several years that cocaine binds to a molecule called the dopamine transporter, thus preventing it from performing its usual job -- which is to remove dopamine from its site of action after initial release.
	www.sciencedaily.com /releases/1998/11/981112075517.htm (1465 words)

	- SHOP.COM
		Neurochemical, neuroprotective and neurorescue effects of aliphatic N-methylpropargylamine: new MAO-B inhibitors without amphetamine-like properties.
		Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: Clinical presentation, cognitive testing, pathology and response to l-deprenyl therapy.
		Monoamines, cytoskeletal elements and psychiatric disorders; a neurochemical fugue.
	www.shop.com /op/aprod-p20749763 (561 words)

	Neurochemical aspects and approaches for neurological diseases
		Symposium on "Neurochemical aspects and approaches for neurological diseases" Neuro 2004
		It is important for the development of therapeutic strategies against the neurological diseases to clarify the detailed mechanisms of onset of the diseases.
		In this symposium, the speakers showed their current works about neurochemical approaches to analyze whole aspects of the neurological diseases.
	www.neurochemistry.org /newsletter/Dec2004/Neurochemicalneurologicaldiseases.htm (1641 words)

	Which Drug & Why: An Update on Psychopharmacology (Site not responding. Last check: 2007-10-03)
		The application of psychopharmacology in the management of behavioral conditions is based on the ability of psychotropic medications to modulate neurochemical function.
		The selection and appropriate use of psychotropics in veterinary patients must be based on the clinician’s assessment of the underlying motivational and neurochemical state for the behavioral disorder.
		To develop an approach to the rational selection and use of psychotropics to behavioral practice, it is critical that the practitioner consider what is known about neurochemical function in relation to the patient’s behavioral signs.
	www.vetsoftware.com /acvc2002-virga6.htm (1824 words)

	Neurochemical Substance P is Key to Understanding Pain Process (Site not responding. Last check: 2007-10-03)
		Neurochemical Substance P is Key to Understanding Pain Process
		In a lecture given to the National Fibromyalgia Partnership, Inc. Dr Russell clearly defined the mechanisms involved in the pain process, and identified the neurochemical Substance P as the key transmitter of pain to the brain.
		In response, the brain dispatches its own batch of neurochemicals, and directs them toward the area of the spinal cord where Substance P had been released.
	www.alzheimersupport.com /library/showarticle.cfm/id/3097/T/Both (661 words)

	BrainTalk Communities - Neurochemical markers for schizophrenia, bipolar disorder, and major depression
		Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brains.
		METHODS: One hundred RNA, protein, and other neurochemical markers were assessed in a single set of 60 postmortem brains (15 each with schizophrenia, bipolar disorder, major depression without psychosis, and unaffected control subjects) in relation to seven neurochemical systems.
		Quantitative measures of continuous variables for prefrontal, hippocampus, anterior cingulate, superior temporal cortex, or a combination of these were analyzed from published and unpublished studies by 56 research groups.
	brain.hastypastry.net /forums/showthread.php?t=65685 (447 words)

	[No title]
		Research in the section is focused on the neuropharmacology of psychosis (emphasizing schizophrenia).
		I was at the hub of a team investigating limbic dopamine D2 receptors, 5HT2a and GABA receptors in schizophrenia, alcohol dependence and depression.
		I head the Section of Neurochemical Imaging and Psychiatry at the IOP and with charitable industrial sponsorship from AstraZeneca, Novartis, Janssen and Sanofi-Synthelabo, have expanded our research portfolio to the mechanisms of antipsychotic induced weight gain, functional magnetic resonance imaging studies of cortical function in first episode schizophrenia, and the neuropsychology of negative symptoms.
	www.iop.kcl.ac.uk /iopweb/departments/home/default.aspx?locator=317 (654 words)

	NEUROCHEMICAL MARKERS OF ALCOHOLISM VULNERABILITY IN HUMANS -- Ratsma et al. 37 (6): 522 -- Alcohol and Alcoholism
		NEUROCHEMICAL MARKERS OF ALCOHOLISM VULNERABILITY IN HUMANS -- Ratsma et al.
		in certain neurochemical indices, as assessed in alcoholics
		Trait marker criteria for neurochemical baseline activities and responses to challenges
	alcalc.oxfordjournals.org /cgi/content/full/37/6/522 (6945 words)

	Human Neurochemical Pathology Laboratory 2003-CAMH (Site not responding. Last check: 2007-10-03)
		Human Neurochemical Pathology Laboratory: Research Annual Report 2003
		The mandate of the Human Neurochemical Pathology Laboratory is to understand the causes of neuropsychiatric disorders by examining the human brain.
		We continue to focus on studies of brain monoamine neurotransmitter systems in people who use amphetamine derivatives (including ecstasy) and in people with Parkinson's disease.
	www.camh.net /Research/Research_publications/Research_AR_2003/human_neurochempath_rar2003.html (480 words)

	Psychologist Says Neurochemical Processes Explain Romantic Attraction » Netscape.com
		Psychologist Says Neurochemical Processes Explain Romantic Attraction » Netscape.com
		Science – "There are several types of chemistry required in romantic relationships," according to Mark B. Kristal, professor of psychology in the UB College of Arts and Sciences.
		"It seems like a variety of different neurochemical processes and external stimuli have to click in the right complex and the right sequence for someone to fall in lo
	science.netscape.com /story/2007/02/14/psychologist-says-neurochemical-processes-explain-romantic-attraction (112 words)

	Serotonergic Attenuation of the Reinforcing and Neurochemical Effects of Cocaine in Squirrel Monkeys -- Czoty et al. ...
		Serotonergic Attenuation of the Reinforcing and Neurochemical Effects of Cocaine in Squirrel Monkeys -- Czoty et al.
		Microdialysis studies were used to investigate the neurochemical mechanism of the observed serotonergic attenuation of the
		One limitation of the present study is that the neurochemical effects were characterized after noncontingent administration
	jpet.aspetjournals.org /cgi/content/full/300/3/831 (5071 words)

	Neurochemical aspects and approaches for neurological diseases
		Symposium on "Neurochemical aspects and approaches for neurological diseases" Neuro 2004
		It is important for the development of therapeutic strategies against the neurological diseases to clarify the detailed mechanisms of onset of the diseases.
		In this symposium, the speakers showed their current works about neurochemical approaches to analyze whole aspects of the neurological diseases.
	neurochem.org /newsletter/Dec2004/Neurochemicalneurologicaldiseases.htm (1641 words)

	[No title] (Site not responding. Last check: 2007-10-03)
		The Section of Neurochemical Imaging is involved in research in the development and use of radioligands for the investigation of psychiatric disorders (with a particular interest in psychosis).
		I have received a unique training in all aspects of neurochemical imaging research.
		This includes data acquisition and large database management, principles and application of parametric image analysis and mathematical modelling of in vivo time activity curves, issues in novel tracer development (for example: precursor labelling, purification, yield optimisation, quality control and metabolite analysis), research team supervision and managerial problem solving.
	www.iop.kcl.ac.uk /iopweb/departments/research/default.aspx?locator=317 (2797 words)

	CAMH: Human Neurochemical Pathology Laboratory 2003 (Site not responding. Last check: 2007-10-03)
		You are here: Home > Research > Research publications > CAMH Research Annual Report 2003 > Neuroscience Research Department 2003 > Human Neurochemical Pathology Laboratory 2003
		The mandate of the Human Neurochemical Pathology Laboratory is to understand the causes of neuropsychiatric disorders by examining the human brain.
		We continue to focus on studies of brain monoamine neurotransmitter systems in people who use amphetamine derivatives (including ecstasy) and in people with Parkinson's disease.
	couragetocomeback.net /research/human_neurochempath_rar2003.html (508 words)

	American Radiolabeled Chemicals, Inc. - Radiolabeled Chemicals, Nucleotides and Radionuclides
		ARC is one of the top three suppliers of radiolabeled chemicals in the world.
		Its 2007 catalog (the biggest in the industry) lists more than 3,500 radiolabeled and unlabeled neurochemicals and biochemicals for life science research.
		Its customers include the major pharmaceutical industries, universities and research institutions in the world.
	www.arc-inc.com /c-12-select-neurochemical-ligands.aspx (215 words)

	A Z Psychiatry
		F00.2 Dementia In Alzheimer's Disease, Atypical Or Mixed Type
		Alzheimer's disease is a primary degenerative cerebral disease of unknown etiology, with characteristic neuropathological and neurochemical features.
		Neurochemical changes have also been found, including a marked reduction in the enzyme choline acetyltransferase, in acetylcholine itself, and in other neurotransmitters and neuromodulators.
	www.azpsychiatry.info /icd/cognitive/alzheimersdementia.htm (779 words)

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