
	Where results make sense

Topic: Neuroleptics

Related Topics

Neuroleptic malignant syndrome

Tardive dyskinesia

Rhabdomyolysis

Hyperthermia

Myocarditis

Creatine kinase

June and Jennifer Gibbons

Myocardial infarction

Injury

Elective mutism

List of neurological disorders

	BioMed Central \| Full text \| Use of neuroleptics in a general hospital
		Neuroleptic drugs are commonly prescribed in acutely ill-hospitalised patients [1-3].
		Neuroleptic drugs are commonly prescribed to treat agitation or delirious states in acutely ill hospitalised patients [1,3].
		As neuroleptics are not innocuous drugs,[28] physicians must recognize that these drugs can promote important side effects, and prior investigators have demonstrated than physicians often lack sufficient knowledge about the therapeutic use and pharmacokinetis of these medications.
	www.biomedcentral.com /1471-2318/2/2 (3206 words)

	WE MOVE - Treatment of Pediatric Movement Disorders - Medication: Neuroleptics
		Neuroleptics are a class of medications that were originally developed to treat psychosis.
		In particular, all neuroleptics, with the exception (thus far) of clozapine have been reported to induce parkinsonism and tardive symptoms, including tardive dyskinesia and tardive dystonia.
		Neuroleptic malignant syndrome, characterized by confusion, stiffening of the muscles, high temperature, and elevated muscle enzymes in the blood, is a rare, potentially life-threatening complication of neuroleptic treatment.
	www.wemove.org /pediatric_treatment/medication_neuroleptics.html (438 words)

	p000216b - Neuroleptic Malignant Syndrome - Treatment
		The neuroleptic malignant syndrome was initially described as a disorder specifically related to neuroleptic usage with frequent fatal outcome.
		The observations of variant or mild cases of this syndrome as well as case reports on neuroleptic-malignant-like syndromes in the absence of neuroleptics raises the issue of the usefulness of this terminology and highlights the potential for inappropriate management of this "malignant" syndrome.
		Out treatment strategy is based on the pharmacology of neuroleptics and empirical data, verified in our own clinical practice and considers that it is often difficult to determine whether certain physiologic states are a consequence to or specific triggering factors.
	www.emory.edu /WHSCL/grady/amreport/litsrch99/p000216b.html (521 words)

	Neuroleptics, psychiatric drug hazards and tardive dyskinesia by Peter R. Breggin, MD
		The neuroleptics are supposedly most effective in treating the acute phase of schizophrenia, but a recent definitive review of controlled studies showed that they perform no better than sedatives or narcotics and even no better than placebo (Keck et al., 1989).
		That the neuroleptics emptied the U.S. mental hospitals is a myth.
		Beyond the specific issue of the neuroleptics, there is a much broader one— how are we to understand and to show care for people who undergo emotional pain and anguish (Breggin, 1991,1992; Mosher and Burti, 1989).
	www.breggin.com /neuroleptics.html (2413 words)

	neuroleptics/antipsychotics
		Neuroleptics have been used on mentally disturbed patients to suppress their emotions and render them passive and docile.
		Neuroleptics have dramatic side effects that are not explicitely mentionned in drug prospectuses nor are they clearly pointed out to patients or family's patients at the time they are prescribed.
		Neuroleptics (antipsychotics) inhibit dopamine nerve transmission in the frontal lobes and in the emotion-regulating limbic system of the brain.
	www.dsuper.net /~styan/neurolep.htm (513 words)

	Bipolar Disorder: Encyclopedia of Medicine
		Because the drug takes four to ten days to reach a therapeutic level in the bloodstream, it is sometimes prescribed in conjunction with neuroleptics and/or benzodiazepines to provide more immediate relief of a manic episode.
		Neuroleptics such as chlorpromazine (Thorazine) and haloperidol (Haldol) are also used to control mania while a mood stabilizer such as lithium or valproate takes effect.
		Because neuroleptic side effects can be severe (difficulty in speaking or swallowing, paralysis of the eyes, loss of balance control, muscle spasms, severe restlessness, stiffness of arms and legs, tremors in fingers and hands, twisting movements of body, and weakness of arms and legs), benzodiazepines are generally preferred over neuroleptics.
	health.enotes.com /medicine-encyclopedia/bipolar-disorder (2925 words)

	[No title]
		The term neuroleptic refers to the theory that these medications “take control of the neuron,” which is supported by their positive affects on psychotic disorders and their extrapyramidal side effects.
		In early treatment with neuroleptics, it was thought that their infrequent or intermittent use as an episodic cure (to be used when the psychosis “flared up”) would be effective in treating the psychosis and minimize the risk of acquiring TD.
		TD suppression by neuroleptics works extraordinarily well in the short term and as a relief from withdrawal-emergent TD, but both Jeste and Egan caution that it is unsound to use the same substance that is causing TD to treat it.
	sulcus.berkeley.edu /mcb/165_001/papers/manuscripts/_741.html (2843 words)

	Thorazine - A Chemical Lobotomy - Permanent Brain Damage and Uses To Control People
		The neuroleptics are synonymous with tranquilizers and antipsychotics.
		The neuroleptics are also used in tranquilizing darts for subduing wild animals and in injections to permit the handling of domestic animals who become viscous.
		Neuroleptic lobotomy, for example, is not a side effect, but the sought-after clinical effect.
	www.sntp.net /drugs/thorazine.htm (1926 words)

	BioMed Central \| Full text \| Effects of two atypical neuroleptics, olanzapine and risperidone, on the function of the ...
		These novel neuroleptics display a complex pharmacological profile with affinities for several receptor systems but are generally characterized by a greater affinity for the 5-HT2A receptor than for the target of the traditional neuroleptics, the D2 receptor [4,5].
		Both neuroleptics decreased the EMG during phase 2, where high frequency oscillations occur in the bladder pressure along with bursting in the EUS, with the highest dose of olanzapine (1.0 mg/kg) abolishing the HFO and the bursting pattern.
		Finally, neither neuroleptic decreased the amplitude of the individual bursts of EMG recorded during phase 2, except for the largest dose of olanzapine (1 mg/kg) that abolished the bursting pattern.
	www.biomedcentral.com /1471-2210/1/4 (5926 words)

	C:\FILES\ARTICLES\sr556nov93.htm
		Neuroleptics are used mainly to treat psychosis but are prescribed, often inappropriately, to treat agitated behavior in demented or mentally retarded patients, who are particularly susceptible to neuroleptic side-effects.
		Highpotency neuroleptics, such as haloperiidol and fluphenazine, are most likely to cause extrapyramidal side-effects, but are less sedating, have less anticholinergic side-effects and cause less orthostatic hypotension than low-potency neuroleptics such as chlorpromazine or thioridazine, which have side-effect profiles that are the inverse of the high-potency neuroleptics.
		Every patient who is prescribed a neuroleptic should have a formal examination for TD, such as the AIMS scale, before initiation of the neuroleptic and every 3 months thereafter that the patient remains on the drug.
	www.brown.edu /Departments/Clinical_Neurosciences/articles/sr55693.html (3221 words)

	Anti-psychiatry - Wikipedia, the free encyclopedia
		In the United States antidepressants and tranquilizers are now the top selling class of prescription drugs, and neuroleptics and other psychiatric drugs also rank near the top, all with expanding sales [18].
		While the insanity defense is the subject of controversy as a viable excuse for wrong-doing, other critics contend that being committed in a psychiatric hospital is often much worse than criminal imprisonment, since it involves the risk of compulsory medication with neuroleptics or the use of electroshock treatment [25].
		Psychiatry is at the forefront of the practice of mental health care in hospital wards, or other medical settings, using legally-sanctioned force to admit individuals against their will.
	en.wikipedia.org /wiki/Anti-psychiatry (3608 words)

	Antipsychotic Medications (Site not responding. Last check: 2007-10-30)
		Loxapine is a medium potency typical neuroleptic with a potency of 10.
		Perphenazine is a medium potency typical neuroleptic with a potency of 10.
		Prochlorperazine is a medium potency typical neuroleptic with a potency of 10.
	members.aol.com /leonardjk/drugs.htm (1975 words)

	A Short Practical Guide to Psychotropic Medications for Dementia Patients (Site not responding. Last check: 2007-10-30)
		Neuroleptic medications diminish psychotic symptoms, including hallucinations, delusions, and disorganization of thought in most patients.
		Neuroleptic dose reductions should proceed in an orderly fashion with frequent monitoring of symptoms.
		Neuroleptic-induced side effects can be managed by switching neuroleptics or adding medication to reverse the side effect; for example, patients who develop muscular stiffness, i.e., drug-induced parkinsonism, on Haldol or risperidone can receive low doses of Cogentin (0.5-1.0 mg BID) to reverse the drug-induced parkinsonism.
	www.alzbrain.org /quicklinks/practguide/neurolepticSimple.htm (1357 words)

	Psychiatric Drugs: Neuroleptics, The Effects of Haldol, Prolixin, Thorazine, Mellaril, and Other Antipsychotic Drugs
		Neuroleptic was coined by jean Delay and Pierre Deniker, who first used the drug in psychiatry, and means "attaching to the neuron." Delay and Deniker intended the term to underscore the toxic impact of the drug on nerve cells (see chapter 4).
		The neuroleptics are the most frequently prescribed drugs in mental hospitals, and they are widely used as well in board-and-care homes, nursing homes, institutions for people with mental retardation, children's facilities, and prisons.
		The neuroleptics also are used in tranquilizer darts for subduing wild animals and in injections to permit the handling of domestic animals who become vicious.
	www.sntp.net /drugs/tranquilizers.htm (5643 words)

	Neuroleptics and Neurotoxicity
		I think that when people seems to respond to neuroleptics, that maybe their brains are sensitive to excess dopamine and the neuroleptics produce a paradoxical effect and suppress dopamine, thus covering up symptoms.
		It has occurred to me that these neuroleptics may be causing the "mental illnesses" in patients by disrupting the neurotransmitter system, and that maybe Dilantin and Centrax in a cocktail dose could help them the way it helped me. Also the SSRI's can cause the same neuroleptic effects, as I found to my detriment.
		Neuroleptics and stigmatization as well as psychosocial causes produce distress that is mistaken for "insanity."
	www.namiscc.org /Editorial/2002/Neuroleptics.htm (599 words)

	Neuroleptics and Brain Damage: An Annotated Bibliography \| 100777.com
		This was a longitudinal study of patients, some schizophrenic, some not, from the beginning of their treatment with neuroleptics until 5 years later.
		Using MRI imaging, this study monitored changes in the size of the basal ganglia and thalamic regions of the brain as patients were treated with neuroleptic drugs.
		For typical neuroleptics, a higher dose was associated with a size increase in multiple areas, while atypcal neuroleptics increased the volume only of the thalamic portion.
	100777.com /node/1341 (1152 words)

	Antipsychotic - Wikipedia, the free encyclopedia
		Antipsychotics are also referred to as neuroleptic drugs, or simply neuroleptics.
		Users typically take smaller doses during the day for the neuroleptic properties and larger dose at bedtime for the sedative effects, or divided in two equally high doses every 12 hours (75-400mg bid).
		Another serious side effect is neuroleptic malignant syndrome, in which the drugs appear to cause the temperature regulation centers to fail, resulting in a medical emergency as the patient's temperature suddenly increases to dangerous levels.
	en.wikipedia.org /wiki/Neuroleptics (1754 words)

	American Experience \| A Brilliant Madness \| Special Features
		In 1963, the NIMH reported that neuroleptics were better than placebo over a six-week period in reducing psychosis, a study that is still cited today as showing the drugs' efficacy.
		As the Canadian investigators concluded: "Some patients who seem to require lifelong neuroleptics may actually do so because of this therapy." This finding has particular relevance for the sub-group of patients, 40% or more, who had done well in the trials in which they were treated with psychosocial care.
		They may not have naturally needed neuroleptics, but once they were exposed to the drugs, they would likely find it difficult to get off them, and thus would be pushed along a path that involved lifelong medication, with all its associated problems.
	www.pbs.org /wgbh/amex/nash/sfeature/sf_forum_0430f.html (1122 words)

	Alzbrain.org Alabama's Alzheimer's Resource (Site not responding. Last check: 2007-10-30)
		Neuroleptics are major tranquilizers that reduce psychotic symptoms, e.g., hallucinations, delusions, and paranoia.
		Neuroleptics do not significantly impair respiratory function, except in high dosages or in combination with other sedating medications, e.g., narcotics, benzodiazepines.
		Neuroleptic Malignant Syndrome (NMS) is a rare but sometimes fatal complication of neuroleptic usage.
	www.alzbrain.org /quicklinks/practguide/sideeffects.htm (1653 words)

	Neuroleptics (Site not responding. Last check: 2007-10-30)
		Tardive dyskinesia is the term used to characterize a neurological disorder caused by long-term treatments with classical neuroleptics.
		Neuroleptics are often utilized in emergency room settings to produce a rapid sedation of psychotic patients.
		Atypical neuroleptics are generally effective in treating both the positive and negative symptoms of schizophrenia.
	www.neurosci.pharm.utoledo.edu /MBC3320/neuroleptics.htm (813 words)

	Neuroleptics from the Law Project for Psychiatric Rights
		Schizophrenia, neuroleptic medication and mortality, by Matti Joukamaa, Markku Helovaara, Paul Knekt, Helio Vaara, Arpo Aromaa, Raimo Ratasalo and Ville Lehtinen, British Journal of Psychiatry (2006), 188, 122-127 found that that in a given time period the relative risk of dying was 2.50 times per increment of one neuroleptic.
		This study documents how the suicide rate went from one half of one percent before the advent of neuroleptics (and deinstitutionalization) to four percent in the modern era where neuroleptics are the standard treatment.
		A Critique of the Use of Neuroleptic Drugs by David Cohen, Ph.D., in From Placebo to Panacea, edited by Seymour Fisher and Roger Greenburg, John Wiley and Sons, 1997 (3.5 mb file).
	psychrights.org /Research/Digest/NLPs/neuroleptics.htm (1747 words)

	The Effects of Neuroleptics on Plasma Homovanillic Acid
		Neuroleptics are potent D2 antagonists, blocking signal transduction to postsynaptic D2 receptors, and interfering with the sensing function of presynaptic D2 receptors (for review, see ref.
		The high concentration of dopamine impinging on the blocked postsynaptic receptors competes with the neuroleptic for the binding site; however, the neuroleptic antagonist has a much higher affinity than dopamine for the postsynaptic D2 receptor and thus is probably only minimally displaced.
		Neuroleptic drugs, which are D2 antagonists, increase tremor amplitude and slow its frequency.
	www.acnp.org /g4/GN401000118/CH116.html (2818 words)

	NEL, Hormonal evaluation in schizophrenic patients treated with neuroleptics
		The aim of this study was to hormonally evaluate schizophrenic patients on long-term treatment with neuroleptics.
		In addition, clinical signs and symptoms of the neuroleptic side effects were evaluated.
		We conclude that PRL levels in schizophrenic patients on long-term therapy with neuroleptics are elevated in about 50% of the women and in 10-20% of the men.
	www.nel.edu /20_34/nel20_34orig6_Hulting.htm (255 words)

	Western Medicine
		Neuroleptics can decrease or eliminate symptoms in about 90% of patients, allowing them to become more functional.
		Typical neuroleptics are the traditional mainstay of antipsychotic treatment.
		Numerous randomized controlled trials have demonstrated efficacy of neuroleptics compared to placebo in reducing symptoms, such that now traditional neuroleptics are considered the "gold standard" and newer treatments must be compared to them in studies (Lieberman et al.)
	altmed.creighton.edu /psychosis/western.htm (300 words)

	Neuroleptic reduction and/or cessation and neuroleptics as specific treatments for tardive dyskinesia
		Neuroleptic medications are effective for the control or reduction of some of the symptoms associated with this illness, but benefits are often accompanied by unwanted adverse effects, including the movement disorder tardive dyskinesia.
		To determine whether a reduction or cessation of neuroleptic drugs is associated with a reduction in TD, for people with schizophrenia (or other chronic mental illnesses) who have existing TD.
		Dyskinesia was found to be not significantly different (n=32, RR 0.62 CI 0.3 to 1.26) between quetiapine and haloperidol when these neuroleptics were used as specific treatments for TD, although the need for additional neuroleptics was significantly lower in the quetiapine group (n=47, RR 0.49 CI 0.2 to 1.0) than in those given haloperidol.
	www.cochrane.org /reviews/en/ab000459.html (750 words)

	Neuroleptics and Chronic Mental Illness
		This was the first large scale study of hospital release rates in the 1950s for schizophrenia patients treated with and without neuroleptics, and it concluded that "drug-treated patients tend to have longer periods of hospitalization." P. Nina Schooler, "One year after discharge: community adjustment of schizophrenic patients," American Journal of Psychiatry, 123 (1967), 986-995.
		This NIMH study looked at one-year outcomes for 299 patients who had been treated either with neuroleptics or placebo upon their admission to a hospital, and was the first long-term study conducted by the NIMH.
		Note that only 45 of the patients in the experimental group were on neuroleptics at 3-year followup, and those on it were on 62 milligrams of Thorazine a day (a very low dose) and that this experimental group had much lower hospital use than those treated conventionally over a three-year followup.
	psychrights.org /Research/Digest/Chronicity/NeurolepticResearch.htm (2868 words)

Try your search on: Qwika (all wikis)